1,851,434 research outputs found
Muir-Torre syndrome - Treatment with isotretinoin and interferon alpha-2a can prevent tumour development
Full text linkMuir-Torre syndrome is a genodermatosis in which multiple internal malignancies are associated with cutaneous sebaceous tumours and kerato-acanthomas. A 57-year-old man presented with multiple sebaceous tumours, kerato-acanthomas, verrucous carcinoma of the nose, renal cell and transitional cell carcinomas of the left kidney, adenoma of the colon and a positive family history of colon carcinoma. He was treated with interferon (IFN-alpha Pa) s.c. 3 x 10(6) U three times a week along with 50 mg isotretinoin daily as well as topical isotretinoin gel. During a follow-up of 29 months, only 1 sebaceous skin tumour developed and was removed, whereas more than 30 such skin tumours had been surgically removed during the last 3 years. No evidence of internal tumour development or recurrence was found. The combination of IFN with retinoids seems to be of promise to prevent tumour development in Muir-Torre syndrome. Copyright (C) 2000 S. Karger AG, Basel
99. Common Law. Protagonisti e Idee nella storia di un sistema giuridico (studi in memoria di Francesco de Franchis)
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La torre inclinada
No full textEsta experiencia muestra cómo construir una torre inclinada que no cae y aborda el concepto de equilibrio y de centro de la gravidade.Para realizar este experimento necesitarás palitos de madera y cartónComponente Curricular::Ensino Médio::Físic
Verifying concurrent programs by memory unwinding
Full text linkWe describe a new sequentialization-based approach to the symbolic verification of multi-threaded programs with shared memory and dynamic thread creation. Its main novelty is the idea of memory unwinding, i.e., an explicit representation of the sequence of write operations into the shared memory. For the verification, we nondeterministically guess this unwinding and then simulate the behavior of the program according to any scheduling that respects this guess. This approach is complementary to other sequentializations and explores an orthogonal dimension, i.e., the number of write operations. It also simplifies the implementation of several important optimizations, in particular the targeted exposure of individual writes. We implemented this approach as code-to-code transformation from multi-threaded into nondeterministic sequential programs, which allows the reuse of sequential verification tools. Experiments show that our approach is very promising: it found all errors in the concurrency category of SV-COMP15
Storia costituzionale del Regno Unito attraverso i Primi ministri
No full textWhat is the job of a British Prime Minister? The elusive response of the Liberal prime minister Herbert Asquith was succinct. «The office of prime minister is what its holder chooses and is able of make of it» (2). Personality, for Asquith, was key to defining the role. Yet individual prime ministers have exercised power over the past 300 years in shifting institutional contexts. Altered relations between the monarch, the cabinet, parliament, political parties and the electorate have framed the aspirations, successes, failures and legacies of those elevated to the political leadership of the country. While the character of the prime minister is key, the levers of power available to them have changed
La torre inclinada
No full textEsta experiencia muestra cómo construir una torre inclinada que no cae y aborda el concepto de equilibrio y de centro de la gravidade.Para realizar este experimento necesitarás palitos de madera y cartónComponente Curricular::Ensino Médio::Físic
La torre inclinada
No full textEsta experiencia muestra cómo construir una torre inclinada que no cae y aborda el concepto de equilibrio y de centro de la gravidade.Para realizar este experimento necesitarás palitos de madera y cartónComponente Curricular::Ensino Médio::Físic
Economia e societa' a Torre del Greco
No full textIlriscatto baronale di Torre del Grco si ebbe grazie allla pesca del corall
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