97,564 research outputs found
Joshua Davis: Author of Spare Parts
No full textCitation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University
Tribute to Professor Grethe Rytter Hasle
No full textGrethe Berit Rytter Hasle was born on January 3, 1920 and passed away peacefully in
her sleep on November 9, 2013 aged 93
Steven Johnson Author Talk Poster
No full textK-State Book NetworkA poster advertising an author talk by Steven Johnson at Kansas State University on September 3, 2014. Steven Johnson's book "The Ghost Map" was the 2014-2015 common book
Lib. IV. Descriptionis imperij Sveo-Gothici. De genio et moribus pop: Sveo-Gothici & Fen[n]ici candidorum ac cordatorum censurae in Regiâ Fennorum Universitate expositus praeside ... m. Michaele VVexionio, juris, polit: & hist: p. p. Respondente Petro And. Wangstelio Wessmanno. [!] Ad diem [ ] Aprilis 1650. Horis locisq[ue] consvetis.
No full textArkit: 1 arkintunnukseton lehti, K-L8, 1 arkintunnukseton lehti.Invokaatio: D.T.O.M.A.Dedikaatio: Elias Andreae, Aeschillus Ambrosii, Daniel Andreae, Gudmundus J. Rothovius, Ericus Michaelis [Rytter], Joannes Aeschilli
Application of Lempel–Ziv factorization to the approximation of grammar-based compression
No full textAbstractWe introduce new type of context-free grammars, AVL-grammars, and show their applicability to grammar-based compression. Using this type of grammars we present O(nlog|Σ|) time and O(logn)-ratio approximation of minimal grammar-based compression of a given string of length n over an alphabet Σ and O(klogn) time transformation of LZ77 encoding of size k into a grammar-based encoding of size O(klogn). A preliminary version of this paper has been presented in Rytter (Combinatorial Pattern Matching, Lecture Notes in Computer Science, vol. 2373, Springer, Berlin, June 2000, pp. 20–31), independently of Charikar et al. (STOC, 2002), where grammar-based approximation has been attacked with different construction and a more complicated type of grammars (α-balanced grammars for α⩽1−122). The AVL-grammar is a very natural and simple tool for grammar based compression, it is a straightforward extension of the classical AVL-tree
An Intrinsic Coordinate System of the Developing Human Brain
No full textwarfield,emiller,sw,zientara,jolesz,kikinis
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Linear-Time Algorithm for Long LCF with k Mismatches
No full textIn the Longest Common Factor with k Mismatches (LCF_k) problem, we are given two strings X and Y of total length n, and we are asked to find a pair of maximal-length factors, one of X and the other of Y, such that their Hamming distance is at most k. Thankachan et al. [Thankachan et al. 2016] show that this problem can be solved in O(n log^k n) time and O(n) space for constant k. We consider the LCF_k(l) problem in which we assume that the sought factors have length at least l. We use difference covers to reduce the LCF_k(l) problem with l=Omega(log^{2k+2}n) to a task involving m=O(n/log^{k+1}n) synchronized factors. The latter can be solved in O(m log^{k+1}m) time, which results in a linear-time algorithm for LCF_k(l) with l=Omega(log^{2k+2}n). In general, our solution to the LCF_k(l) problem for arbitrary l takes O(n + n log^{k+1} n/sqrt{l}) time
Mechanisms of Ischemic Brain Injury- studies in murine hippocampal slice cultures
No full textCerebral ischemia is a major cause of mortality and morbidity in the western world. Even though much effort has been put into research and development of effective drugs against ischemic damage there is to date no effective pharmacological brain protective treatment. In order to study particular molecular mechanisms, isolated cellular events and the contribution of individual factors in ischemic damage, in vitro models resembling the in vivo situation are needed. The aim of this thesis was to establish and describe an in vitro model of ischemia that reproduces the cell death pattern following ischemia in vivo, using mouse organotypic hippocampal slice cultures. In most models, in vitro ischemia is mimicked by the deprivation of oxygen and glucose (OGD) in a medium with an ion composition similar to that of the extra cellular fluid of the normal brain (2-4 mM K+, 2-3 mM Ca2+ and pH 7.4). During in vivo ischemia the distribution of ions across cell membranes shifts. We therefore exposed cultures to OGD in a medium with 70 mM K+, 0.3 mM Ca2+ and pH 6.5-6.8, similar to the extracellular fluid of the brain during ischemia in vivo. Damage induced by 12-15 minutes of OGD in this medium is delayed and observed only in the CA1 region, similar as in in vivo models of ischemia. Another feature of in vivo ischemia is the aggravating effect of glucose on damage. In our model high levels of glucose during the insult delayed and aggravated damage. Our results demonstrate that glucose in combination with acidosis mediates the detrimental effect. The cell death caused by glucose-free ischemia was inhibited by antagonists of ionotropic glutamate receptors, but when glucose was present during ischemia the same antagonists had no effect. Hypothermia is the most powerful method for protecting the brain from ischemic damage. In our model hypothermia of 31°C during both IVI and hyperglycemic IVI provided profound protection, whereas hypothermia only after the insult did not affect the development of damage in either of the paradigms. Following glucose-free ischemia no immunoreactivity of activated caspase-3 could be seen and neither was there any effect of a pancaspase inhibitor, instead activation of the MPTP was induced. In the hyperglycemic paradigm the dentate gyrus displayed active caspase-3 and cell death in this region was abolished by the caspase inhibitor. Cell death in the CA1 region following hyperglycemic IVI could have a component of caspase activity, but neither the MPTP nor caspases play critical roles. Activation of adenosine A1 receptors (A1Rs) is thought to be protective. But the deletion of the A1R-gene did not influence the outcome neither following ischemia in a mouse global ischemia model nor following in vitro ischemia. The results suggest that some effects of A1 receptors are compensated for in knockout animals. In conclusion this model of in vitro ischemia mimics central features of in vivo ischemia and can be useful in future studies of the mechanisms and treatment of ischemic cell death
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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