1,720,967 research outputs found
POLYSACCHARIDE DOUBLE-LAYER MICROCAPSULES AS CARRIERS FOR BIOLOGICALLY ACTIVE SUBSTANCE ORAL ADMINISTRATION
No full textThe present invention relates to microcapsules with a double-layer of natural polysaccharides - chitosan and alginate - gelified and stabilized by means of a divalent ion containing inside at least one biologically active substance. The microcapsules of the invention can be employed as carriers for the oral administration of biologically active substances, also associated with an adjuvant of the biological response of the same, administered for a preventive or therapeutic purpose. These substances can be chosen, for example, from antigens and adjuvants, suitable for immune response stimulation against infective and non-infective agents, or from chemotherapeutics and adjuvants with therapeutic type effects. According to the type of biologically active substance encapsulated in the microcapsules, there can be a variety of uses for oral vaccination or therapy in the human and veterinary field
IMPIEGO DI MICROCAPSULE A DOPPIO STRATO DI POLISACCARIDI VEICOLANTI LISOZIMA PER IL TRATTAMENTO DELLA NEFROPATIA DIABETICA
No full textMETHOD AND APPARATUS FOR PREPARING MICRO-PARTICLES OF POLYSACCHARIDES
No full textThe present invention relates to a method for the production of micro-particles of polysaccharides. The method includes preparing a feeding solution and a gelifying liquid to collect nebulized jets of the feeding solution. The feeding solution contains at least one polymer capable of forming micro-particle structures and at least one biologically active substance. The feeding solution is pressurized inside an air-less nebulizing unit and then nebulized through the unit itself so as to generate nebulized jets impacting the surface of the gelifying liquid
Synthesis of 11-aryl-5H-imidazo[2,1-c][1,4]benzodiazepines and their benzodiazepine and A1 adenosine binding activity.
No full textSynthesis of 11-aryl-5H-imidazo[2,1-c][1,4]benzodiazepines and their benzodiazepine and A1 adenosine binding activity
No full textOral poly (ethylene glicol)-coniugated human recombinant lysozyme control of lung metastases in mice
No full textPolyostotic fibrous dysplasia involving the sternum
No full textThe authors present a case of polyostotic fibrous dysplasia involving the sternum as well. The case is well supported the strumental and histological point of view
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
- …
