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Tiroiditi distruttive in pazienti affetti da HCV epatite in terapia con interferone: la nostra esperienza.
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Course of Graves’ disease manifested during therapy with IFN in individuals with HCV hepatitis compared to GD in controls.
No full textHeart failure and acute pulmonary edema linked to sepsis: a case report and a short review of literature
No full textHeart failure is a most dangerous and insidious complication of the septic state. We describe the case of a patient admitted to our department for weakness of all four limbs and fever. During hospitalization the patient developed a septic state that has manifested itself through the development of heart failure with acute pulmonary edema
Course of Graves' disease in interferon-treated patients with chronic hepatitis C virus infection and in uninfected patients
No full textBACKGROUND:
The development of thyroid antibodies and the alteration of thyroid function are the most common disorders associated with interferon alfa therapy in individuals with chronic hepatitis C (CHC).In this study, we compared the course of Graves disease (GD) between patients diagnosed with CHC and treated with interferon alfa and uninfected patients.
METHODS:
We retrospectively analyzed data from 39 GD patients (15 men and 24 women, group 1) affected by CHC and treated with interferon alfa and from 43 uninfected GD patients (19 men and 24 women, group 2) who were seen at our institution from 1999 to 2011. All GD patients were treated with methimazole (MMI). Daily dose of MMI, duration of MMI therapy, and remission rate were evaluated in both groups.
RESULTS:
The daily dose of MMI was found to be lower in group 1 as compared with group 2 (9.74 ± 5.94 mg/d vs 14.12 ± 8.64 mg/d in group 1 vs group 2, respectively, P < 0.01). In addition, the duration of MMI treatment was found to be lower in group 1 as compared with group 2 (13.98 ± 13.0 months vs 38.86 ± 27.13 months in group 1 vs group 2, respectively; P < 0.01). The remission rate from GD was higher in the patients of group 1 in comparison with the patients of group 2 (87.17 % vs 48.86% in group 1 vs group 2, respectively, P < 0.005).
CONCLUSION:
Altogether, our data demonstrate a more favorable course of GD in the patients with CHC treated with interferon alfa compared with GD occurring in the patients without CHC
STUDIO E COMPARAZIONE DELLE ALTERAZIONI DI FUNZIONALITA’ TIROIDEA INDOTTE DA INTERFERONE NEI SOGGETTI CON EPATITE CRONICA ATTIVA DA VIRUS C RISPETTO A SOGGETTI DI CONTROLLO
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
ALTERAZIONI DELLA FUNZIONALITA’ TIROIDEA IN PAZIENTI AFFETTI DA EPATITE CRONICA ATTIVA DA VIRUS C IN TERAPIA CON INTERFERONE E RIBAVIRINA E CORRELAZIONE CON LA RISPOSTA ALLA TERAPIA ANTIVIRALE
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