574 research outputs found
Diagnosis and analysis as the first steps in a turnaround management process model
No full textAuthor Fabio Damm, BScDiplomarbeit Universität Linz 201
Energy Transfer Mechanisms in the KCl:Eu2+,Mn2+ System
No full textEnergy-transfer mechanisms have been examined in the KCl:Eu2+,Mn2+ system at low Eu- and Mn-ion concentrations. The Eu ions represent the donor system, the Mn ions the acceptor one. No transfer evidence has been found in quenched samples; by annealing the samples at temperatures higher than 200 °C, the typical Mn2+ emission is observed after excitation in the Eu2+ absorption band. The energy-transfer mechanisms have been examined along the aggregation process induced by annealing the KCl:Eu2+,Mn2+ samples at 225 °C for very long times: three different types of behavior have been evidenced. In the early annealing stages a single pair donor-acceptor transfer mechanism is observed, while at longer annealing times an energy diffusion in the donor system, followed by a phonon-assisted transfer, takes place. Finally, at very long annealing times the energy diffusion process is followed by a resonant transfer mechanism
Inherent Causal Orderings of Partial Order Scenarios
No full textScenario based requirements specifications are the industry norm for defining communication protocols. Basic scenarios captured as UML sequence diagrams, Message Sequence Charts (MSCs) or Live Sequence Charts (LSC) have partial order semantics that characterize system traces by restricting the possible order of events within those traces. The semantic partial order of the scenario specification is called the causal ordering. Semantic inconsistencies often occur in partial order scenarios between the specified causal ordering and the order that events can occur in practice. Such inconsistencies are known as race conditions. The paper proves that there is a unique race free partial order that is a minimal weakening of the causal ordering. In other words, there is a canonical generalization of the requirements that corrects all race conditions. Hence any race free generalization of the original scenario is in fact a generalization of the canonical scenario. The paper also proves the dual result, there is a unique race free partial order that is a minimal strengthening of the causal order. I.e. there is a canonical refinement of the requirements that corrects all race conditions
The impact of long-term maintenance treatment with buprenorphine on complex psychomotor and cognitive function
No full textIntroduction: Despite the fact that buprenorphine is effective, well tolerated and due to its pharmacological profile a very safe drug, the impact of long-term buprenorphine substitution therapy on complex psychomotor and cognitive function predicting driving ability is not yet clear. Therefore, a prospective comparison between patients receiving sublingual buprenorphine and a control group of untreated, healthy volunteers was performed. Methods: Treated and untreated subjects were matched for age and sex, with three control subjects selected for every buprenorphine patient. Patients using unreported drugs were included in the intention-to-treat (HT) analysis; the remaining patients were analysed as the per-protocol (PP) group. The test battery comprised the assessment of: performance during stress, visual orientation, concentration, attention, vigilance and reaction time. The primary endpoint was defined as the sum of the relevant scores of the tests after z-transformation of the individual scores. Results: 30 patients with sublingual buprenorphine treatment (7.7 +/- 3.9 mg per day) were matched to 90 controls. 19 patients were excluded from the PP-analysis because of additional unreported drug intake. Significant non-inferiority could be demonstrated for the PP-group (p < 0.05) as well as for the HT-group (p < 0.001). Conclusion: Patients receiving a stable dose of sublingual buprenorphine showed no significant impairment of complex psychomotor or cognitive performance as compared to healthy controls. However intake of illicit drugs as well as the lack of social reliability are major problems in this specific patients group. Despite of the absence of a relevant impact of the drug on driving ability, those patients do not seem to be qualified for getting their driving license. (C) 2011 Elsevier Ireland Ltd. All rights reserved
An address to the public. On true representation and the unity of man. [electronic resource] : Being the substance of a speech, delivered at the Free Masons Lodge, in Sheffield. On Monday February 27th. 1792. By Benjamin Damm, A Member of the Constitutional Society. Together with A rhapsody to E----- B---- Esq. By J. Sharpe. Ornamented with a humorous print, of "the swinish multitude".
No full text'A rhapsody to E----- B---- Esq' has separate pagination, register and titlepage dated 1792.E----- B---- Esq. = Edmund Burke.Price from imprint: price Three-Pence.Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library
Die Anwendung von Modellierungsmethoden im Rahmen der gesundheitsökonomischen Evaluation von Impfungen in Deutschland
No full textDamm O. Die Anwendung von Modellierungsmethoden im Rahmen der gesundheitsökonomischen Evaluation von Impfungen in Deutschland. Bielefeld: Universität Bielefeld; 2018.Entscheidungsträger im Gesundheitswesen sind zunehmend an der Einbindung gesundheitsökonomischer Analysen in den Bewertungsprozess neuer Gesundheitsleistungen interessiert, nicht zuletzt aufgrund steigender Ausgaben im Arzneimittelsektor. Gleichzeitig sind auch pharmazeutische Hersteller bemüht, zu belegen, dass ihre Produkte "good value for money" bieten. Insbesondere bei Empfehlungs- und Erstattungsentscheidungen im Impfstoffsektor gehören gesundheitsökonomische Aspekte mittlerweile in vielen Ländern zum festen Bestandteil des Kriterienkatalogs, der bei der Evidenzbewertung zur Anwendung kommt. Die entscheidungsanalytische Modellierung kann dabei helfen, die Kosteneffektivität von Impfungen zu analysieren. Sie stellt sogar eine Schlüsselmethode bei der Evaluation von Impfungen dar, da sie die Abschätzung langfristiger epidemiologischer und gesundheitsökonomischer Auswirkungen von Impfungen auf Bevölkerungsebene ermöglicht.
Vor diesem Hintergrund verfolgt die Dissertationsschrift das Ziel, einen Überblick über spezifische methodische Herausforderungen der modellbasierten gesundheitsökonomischen Evaluation von Impfungen zu geben und auf Basis einer Reihe von Modellierungsstudien die langfristigen epidemiologischen und gesundheitsökonomischen Effekte verschiedener Impfungen in Deutschland zu untersuchen. Die Auswahl der evaluierten Schutzimpfungen umfasst Impfstoffe gegen Humane Papillomviren (HPV), das Varicella-Zoster-Virus (VZV) sowie saisonale Influenza.
Mit der Zusammenstellung von acht in Fachzeitschriften publizierten Beiträgen unterschiedlichen Charakters leistet die vorliegende Arbeit einen wichtigen Beitrag zur Erforschung der epidemiologischen und gesundheitsökonomischen Konsequenzen von Impfungen in Deutschland. Die Arbeit stellt zugleich eine wertvolle Grundlage für den Entscheidungsfindungsprozess hinsichtlich der Entwicklung oder Überarbeitung von Impfempfehlungen dar. Die Modellanalyse zu den ökonomischen Effekten der Influenza-Impfung zeigt bspw., dass die routinemäßige Impfung von Kindern und Jugendlichen gegen Influenza aus gesellschaftlicher Perspektive eine kostensparende Intervention darstellt. Wie die in die vorliegende Arbeit eingegangenen modellbasierten Studien demonstrieren, ist die Berücksichtigung der Transmissionsdynamik von hoher Relevanz, um neben direkten Impfeffekten auch indirekte Effekte (z. B. Herdenschutzeffekte) in die Ergebnisse einzubeziehen. Die Zusammenstellung der Beiträge macht dabei ebenfalls deutlich, dass sich indirekte Effekte nicht nur positiv, sondern auch negativ auf die Beurteilung einer Impfung auswirken können.
Zukünftig gilt es, die Datenbasis für entscheidungsanalytische Modelle in Deutschland zu verbessern und bislang unberücksichtigte Aspekte in die modellbasierte Evaluation von Impfungen zu integrieren. Dazu zählt u. a. der durch präventive Maßnahmen induzierte Antizipationsnutzen. Bevor entsprechende Effekte jedoch in Modellen berücksichtigt werden können, bedarf es zunächst weiterer Forschung zur Messung dieser Nutzenkomponente
Characterizing Communication Channel Deadlocks in Sequence Diagrams
No full textUML sequence diagrams (SDs) are a mainstay of requirements specifications for communication protocols. Mauw and Reniers' algebraic (MRA) semantics formally specifies a behaviour for these SDs that guarantees deadlock free processes. Practitioners commonly use communication semantics that differ from MRA, which may result in deadlocks. For example FIFO, token ring, etc. We define a process algebra that is an extension of the MRA semantics for regular sequence diagrams. Our algebra can describe several commonly used communication semantics. Regular SDs are constructed from concurrent message flows via iteration, branching, and sequential composition. Their behaviour is defined in terms of a set of partial orders on the events in the SD. Such partial orders are known as causal orders. We define partial order theoretic properties of a causal order that are particular kinds of race condition. We prove any of the common communication semantics we list either guarantees deadlock free SDs or can result in a deadlock if and only if a causal order of an SD contains one of these types of race condition. This describes a complete classification of deadlocks as specific types of race condition
Single-phase synchronous reluctance motor with asynchronous start- up
No full textIn this paper a new concept of a single-phase reluctance motor with asynchronous start-up is shown. The paper describes a way of evolving of construction to achieve the final successful result. Details of the "hybrid" rotor construction and motor characteristics are shown. The main advantage of these motors are synchronous operation with single-phase supply and simple and cheap motor construction based on a squirrel-cage induction motor
Experiences of Cantoni Group in developing of energy efficient motors
No full textThis paper presents experiences of Polish manufacturers of electric motors combined in Cantoni Group in designing and producing of energy efficient motors. New products of Cantoni Group in scope of energy efficient motors are presented. Moreover Cantoni Group cooperate with European and American Units that certify energy efficient motors. One of the most important problems is to unify mothods of determining of efficiency
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