6,653 research outputs found
Shall we see Michael's like again?
No full textKenneth O. Morgan pays tribute to veteran Labour politician Michael Foot, who died in March 2010 Copyright (c) 2010 The Author. Journal compilation (c) 2010 ippr.
"Objects Lost and Found: Kenneth Patchen's Poetics of the Letter"
No full textIn "Oggetti perduti e ritrovati: Kenneth Patchen e la poetica della lettera" gli aspetti storici e letterari di una poesia di Kenneth Patchen,"Poem in the form of a Letter: to Lauro de Bosis", sono esplorati analiticamente al fine di individuarne gli aspetti 'oggettivi' derivati dalla lezione di Zukofski che, negli anni trenta, iniziò a promuove l'oggettivismo in poesia, seguito da poeti come Ron Silliman, Bob Perelman e Rachel Blau DuPlessis ai nostri giorni.A poem by Kenneth Patchen "Poem in the form of a Letter: to Lauro de Bosis" is explored analytically by the author in order to discover its 'objective' aspects as derived from the lesson of Zukofsky who, in the thirties, set out to promote the "objectivism" in poetry, and was followed by poets like Ron Silliman, Bob Perelman and Rachel Blau DuPlessis, who are very active in today’s “objective” panorama
Letter Written by Kenneth B. Hazard to the Bryant College Service Club Dated February 2, 1943
No full text[Transcription begins]
U. S. COAST GUARD 40 Broad Street Boston, Mass. February 2, 1943
Bryant Service Club Bryant College 1 Young Orchard Avenue Providence, R. I.
Gentlemen:
It is with deep regret that acknowledgement of receipt of your package has not been made before this time. However, there certainly must have been a delay in the delivery of this package as I did not receive it until January 18, 1943. In all probability this delay was caused within the Office at Boston, Mass., as has been the case in the past.
Nevertheless, the cigarettes were very much appreciated and many thanks for them. It is always nice to know that your old friends are thinking of you. I am rather fortunate in my present situation to have many old college friends here with me. It almost seems like the days back at Bryant.
Thank you again for the remembrance.
Yours very truly Kenneth B. Hazard S.K. 1/c [Transcription ends
Angiopoietin‐1 negatively regulates expression and activity of tissue factor in endothelial cells
No full textNormally, tissue factor (TF) is not expressed on the surface of endothelial cells, but its expression can be induced by vascular endothelial growth factor (VEGF) and tumor necrosis factor (TNF)-alpha. However, the signaling pathway(s) affecting this induction is unknown. Using human umbilical vein endothelial cells, we found that inhibitors of guanine-cytosine-rich DNA binding protein and nuclear factor (NF)-kappaB suppressed VEGF- and TNF-alpha -induced expression and activity of TF. However, unexpectedly, phosphatidylinositol (PI) 3'-kinase inhibitor enhanced the VEGF- and TNF-alpha -induced expression and activity of TF. Angiopoietin-1 (Ang1), a strong activator of intracellular PI 3'-kinase/Akt, inhibited the induction of TF by VEGF and TNF-alpha, whereas Ang1 itself did not produce any significant effect on TF. Selective activation (or inactivation) of PI 3'-kinase/Akt by using adenoviral transfer reduced (or enhanced) TNF-alpha -induced expression of TF mRNA and protein, regardless of Ang1 treatment. From these results, we conclude that Ang1 inhibits the up-regulation of TF expression, possibly through activation of PI 3'-kinase/Akt in endothelial cells. Ang1 may be useful as an inhibitor of VEGF- and TNF-alpha -induced coagulation, inflammation, and cancer progression
'Rare and refreshing fruit': Lloyd George's People's Budget
No full textIn its centenary year, Kenneth O. Morgan, explains the profound significance of Lloyd George's People's Budget for our political, social and economic history Copyright (c) 2009 The Author. Journal compilation (c) 2009 ippr.
Lrp acts as both a positive and negative regulator for type 1 fimbriae production in Salmonella enterica serovar Typhimurium.
No full textLeucine-responsive regulatory protein (Lrp) is known to be an indirect activator of type 1 fimbriae synthesis in Salmonella enterica serovar Typhimurium via direct regulation of FimZ, a direct positive regulator for type 1 fimbriae production. Using RT-PCR, we have shown previously that fimA transcription is dramatically impaired in both lrp-deletion (Δlrp) and constitutive-lrp expression (lrp(C)) mutant strains. In this work, we used chromosomal P(fimA)-lacZ fusions and yeast agglutination assays to confirm and extend our previous results. Direct binding of Lrp to P(fimA) was shown by an electrophoretic mobility shift assay (EMSA) and DNA footprinting assay. Site-directed mutagenesis revealed that the Lrp-binding motifs in P(fimA) play a role in both activation and repression of type 1 fimbriae production. Overproduction of Lrp also abrogates fimZ expression. EMSA data showed that Lrp and FimZ proteins independently bind to P(fimA) without competitive exclusion. In addition, both Lrp and FimZ binding to P(fimA) caused a hyper retardation (supershift) of the DNA-protein complex compared to the shift when each protein was present alone. Nutrition-dependent cellular Lrp levels closely correlated with the amount of type 1 fimbriae production. These observations suggest that Lrp plays important roles in type 1 fimbriation by acting as both a positive and negative regulator and its effect depends, at least in part, on the cellular concentration of Lrp in response to the nutritional environment
HEB874841_suppl_mat – Supplemental material for Development and Pretesting of Risk-Based Mobile Multimedia Message Content for Young Adult Hookah Use
No full textSupplemental material, HEB874841_suppl_mat for Development and Pretesting of Risk-Based Mobile Multimedia Message Content for Young Adult Hookah Use by Lorien C. Abroms, Robert S. Gold, John P. Allegrante, Andrea C. Johnson, Isaac Lipkus, Kenneth P. Tercyak, George Luta, Kathryn Rehberg, Lilianna Phan, Lorien C. Abroms and Darren Mays in Health Education & Behavior</p
Programming Fundamentals : A Modular Structured Approach using C++, 1st edition
No full text1. Preface2. Author Acknowledgements3. Orientation and Syllabus4. Sharing/Rating Connexions Materials5. Introduction to Programming6. Program Planning & Design7. Data & Operators8. Often Used Data Types9. Integrated Development Environment10. Program Control Functions11. Specific Task Functions12. Standard Libraries13. Character Data, Sizeof, Typedef, Sequence14. Introduction to Structured Programming15. Two Way Selection16. Multiway Selection17. Test After Loops18. Test Before Loops19. Counting Loops20. String Class, Unary Positive and Negative21. Conditional Operator and Recursion22. Introduction to Arrays23. File I/O and Array Functions24. More Array Functions25. More on Typedef26. Pointers27. More Arrays & Compiler Directives28. OOP & HPCProgramming Fundamentals - A Modular Structured Approach using C++ is written by Kenneth Leroy Busbee, a faculty member at Houston Community College in Houston, Texas. The materials used in this textbook/collection were developed by the author and others as independent modules for publication within the Connexions environment. Programming fundamentals are often divided into three college courses: Modular/Structured, Object Oriented and Data Structures. This textbook/collection covers the first of those three courses
Discrete mathematics and its applications / Kenneth H. Rosen.
No full textIncludes bibliographical references (p. B-1 - B-7) and index.xxii, 843, A-15, B-7, S-90, C-1, I-18 pages.
Best practices in serials management: a Kenneth Dike Library model
No full textSerials are described as a group of important information resources which contain primary cutting edge information, especially in an academic library like the Kenneth Dike Library, University of Ibadan, Nigeria. The various processes involved in the effective management of serials are highlighted in this paper. Automation of serials collection and electronic serials were discussed; serials workflow diagrams representing manual and automated serials management systems were also developed by the author
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