485 research outputs found
抗線維化薬を志向した選択的TGF-B RII阻害剤の開発
No full text博士論文 要旨Abstract/本文Full以下に掲載：ACS Medicinal Chemistry Letters 12(5) pp.745-751 2021. American Chemical Society. 共著者：Shohei Miwa, Masahiro Yokota, Yoshifumi Ueyama, Katsuya Maeda, Yosuke Ogoshi, Noriyoshi Seki, Naoki Ogawa, Jun Nishihata, Akihiro Nomura, Tsuyoshi Adachi, Yuki Kitao, Keisuke Nozawa, Tomohiro Ishikawa, Yutaka Ukaji, Makoto Shiozak
Psychological Experiences of Elderly Patients With Covid-19 Diagnosis in Intensive Care: A Qualitative Study
No full textIn the study, it was aimed to determine the experiences of elderly COVID-19 patients hospitalized in intensive care units. The study was conducted based on the phenomenological design, one of the qualitative research methods. In-depth interviews were conducted using a semi-structured interview form with 15 participants, who were determined by the homogeneous and criterion sampling methods, two of the purposive sampling methods. Data were analyzed using Colaizzi’s seven-step method. After the interviews, four themes were determined: intensive care experiences, importance of nursing care, intensive care environment and coping mechanisms related to COVID-19 disease, and post-intensive care realizations. In addition, 13 sub-themes were determined. This study provided a better understanding of the psychological experiences of elderly individuals during the disease, who have been hospitalized in intensive care unit and survived COVID-19. © The Author(s) 2022
Exploratory Analysis of Usage Statistics of Dialogue Systems by Visualization
No full textIt is important to analyze the usage statistics of dialogue systems in order to identify improvements that can increase user satisfaction. However, further beneficial information may be hidden among the information (such as logs and registered usage statistics in the database) that is not output as a result of the general analysis methods and can be discovered through exploratory analysis. To this end, this study proposes a method for the exploratory analysis of the usage statistics of dialogue systems using visualization to detect beneficial information, either intentionally or unintentionally. Specifically, usage statistics are visualized as network graphs showing the queries and transitions among them, and functions to extract particular visualized objects and identify characteristic queries are implemented to support the analysis. The results of this evaluation show that the proposed method can detect beneficial information through an exploratory analysis of visualized usage statistics, thereby demonstrating its effectiveness in the analysis of dialogue systems
(Motoaki Saito, 1805) and Yuseido Wasan School (The study of the history of mathematics 2018)
No full text"The study of the history of mathematics 2018". September 18-21, 2018. edited by Shigeru Jochi. The papers presented in this volume of RIMS Kôkyûroku Bessatsu are in final form and refereed.Sukesada Hirose 広瀬祐貞(?-1882?), 10^{th} principal of Seki-ryu 関流 school, was mathematician from the end of Edo period to the Meiji period, and founded the wasan school of Yuseido 由精堂 at Shinshiro 新城, Mikawa 三河(now Aichi 愛知 prefecture). His school was one of the Seki-ryu school, however, its curriculum was quite unique with other Seki-ryu schools. The author thinks the mathematical works of Murahide Araki 荒木村英(1640-1718), the 2^{nd} principal of Seki-ryu school, was influenced on Hirose's school. It was said that Hirose wrote the Sanpo Shoyaku-jutsu 算法諸約術 in 1805 although there were a few historical materials about Hirose. The Heizaemon Kato's 加藤平左ヱ門(1891-1976)Wasan correction at Taihoku Imperial University 台北帝国大学(now National Taiwan University 国立台湾大学) was discovered in 2004, and the author discovered 66 mathematical arts concerned with Hirose. Then his school was founded at Shishiro, Aichi prefecture, and he was died about 1882. Therefore the author conclude that Hirose did not write the Sanpo Shoyaku-jutsu, and it was written by Motoaki Saito 斎藤元章(1765-1812), 6^{th} principal of Seki-ryu school, and the Sanpo Shoyakujutsu was infuluenced by the Saijo-ryu 最上流 school of Yasuaki Aida 会田安明 (1747-1817)
Some Remarks on the approximate calculation of Pi by SEKI Takakazu and TAKEBE Katahiro : on the occasion of the 314th anniversary of SEKI Takakazu (Study of the History of Mathematics 2022)
No full textTo activate the study on the history of Mathematics in Japan, the author proposed to organize some memorial events for the year 2022, the 314th year after his death of SEKI Takakazu(?-1708), the 300th anniversary of TAKEBE Katahiro’s “Tetsujjutsu-Sankei”, and so on. In this time, we give some remarks on the approximate calculation of Pi by SEKI Takakazu and TAKEBE Katahiro. We also mention the work of KAMATA Yoshikiyo on the same problem. , especially he gave the length of circumscribed. polygon with it of inscribed polygon. We claim that Seki and Takebe used better method giving lower and upper bounds of Pi than Kamata did. In this point of view, we criticize some observation on given by hisitorian on science about mathematicians of Edo era. of Japan. From this episode, we learn a lesson on mathematics education: maticians should give explanation easy to nderstand on their works to the society and mathematics education should be done iin a reasonable way n the society.数学，数学教育，数学史の教育・研究の活性化のために2022年に関孝和314年祭開催等を（建部賢弘が「綴術算経」の序文を書いてから300年の記念の年でもあり）提唱していた．今回は，関孝和と建部賢弘の円周率の近似計算に関するいくつかの注意を与えておく．鎌田俊清が円周率の近似計算において内接正多角形の周長とともに外接正多角形の周長も与えられていることに言及し，円周率の下界と上界を与えるよりよい方法を，関や建部は使っていることを主張する．この観点から, ある科学史家の日本の江戸時代の数学者についての観察を批判する．この逸話から数学教育についての教訓を得る：数学者はその成果をわかりやすく社会に伝えるべきであり、社会ではある程度の数学力を備えるべく数学教育が必要である
Formation of a broad plasma turbulent layer by forward and inverse energy cascades of the Kelvin-Helmholtz instability
No full textThe secondary instability initiated by the three-dimensional nonlinear evolution of the Kelvin-Helmholtz instability
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