2,059 research outputs found
332. Kenji-kin
Iwao Seiichi, Iyanaga Teizō, Ishii Susumu, Yoshida Shōichirō, Fujimura Jun'ichirō, Fujimura Michio, Yoshikawa Itsuji, Akiyama Terukazu, Iyanaga Shōkichi, Matsubara Hideichi. 332. Kenji-kin. In: Dictionnaire historique du Japon, volume 12, 1986. Lettre K (2) p. 60
HASTE DE LÍRIOS, DE KENJI MIYAZAWA
The present work is a translation from Japanese to Brazilian Portuguese of the Yomata no Yuri (Stem of Lillies) tale written by the Japanese author Kenji Miyazawa (1893-1933). Miyazawa was an essayist, poet and writer of Japanese children's tales. Even though his work is not so popular in Brazil, in Japan it has achieved much notoriety. He is considered one of the most relevant writers in both prose and poetry. Miyazawa was born in Iwate and graduated in Agricultural Sciences. He was also a professor and dedicated himself fundamentally to the writing career. His work is notably influenced by Nichiren Buddhism, which can be seen in the following work. This translation aims at presenting to the Brazilian public an example of the Kenji’s literature, considering the cultural relevance of his work and the importance for understanding the Japanese way of thinking.O presente trabalho é uma tradução para o português do Brasil do conto Yomata no Yuri (Haste de Lírios) do autor japonês Kenji Miyazawa (1893 – 1933). Miyazawa foi ensaísta, poeta e escritor de contos japoneses infantis. Embora a obra dele não seja tão conhecida no Brasil, no Japão ela alcançou bastante notoriedade, podendo ser considerado um dos escritores mais relevantes tanto na prosa, quanto na poesia. Miyazawa nasceu na prefeitura de Iwate, graduou-se em Ciências da Agricultura, foi professor universitário e dedicou-se fundamentalmente à carreira de escritor. Sua obra apresenta forte influência do Budismo Nichiren, como pode ser visto pela leitura do conto a seguir. Esta tradução visa a apresentar ao público brasileiro um exemplo da literatura de Kenji, tendo em vista a riqueza cultural de seu trabalho, bem como relevância para o entendimento do pensamento japonês
Miyazawa Kenji and a Tale of “Kanji”
Miyazawa Kenji (1896-1933), a poet and author of children’s stories, spent much of his life laboring to improve the material and spiritual lives peasants in the impoverished farming communities of Iwate Prefecture. He received little notice during his lifetime, but since the Second World War the sincerity of his work, reflecting a life of spiritual struggle, has attracted growing attention. In this paper we examine relationship between kanji and Miyazawa Kenji and the meaning of kanji for him referring some works including Otsuberu to Zou (1926, literally Otsuberu and the Elephant) and Kaze no Matasaburō (1934, literally Matasaburō of the Wind)
Design of pharmaceutical tablet formulation for a low water soluble drug : search for the critical concentration of starch based disintegrant applying percolation theory and F-CAD (Formulation-Computer Aided Design)
The topic of this PhD work is to search the critical concentration of starch based disintegrant applying percolation theory and F-CAD (Formulation-Computer Aided Design) in order to design a pharmaceutical tablet formulation for a low water soluble drug. Critical concentration of maize starch (MS) for a ternary mefenamic acid (MA) tablet formulation with respect to a minimum disintegration time is investigated. Additionally implemented application of F-CAD to compute the disintegration time of MA tablet formulation is presented. This topic is related to push forward the idea of Quality by Design (QbD) of FDA (Food and Drug Administration) / EMEA (European Medicines Agency) / PMDA (Pharmaceuticals and Medical Devices Agency) and the exploration of the design space according to ICH (International Conference of Harmonization) Q8.
The results of this work shows that the application of percolation theory is not limited to binary tablet formulation. The critical concentration of MS described by the renormalized MS concentration, MS/(MS+MA) applying the renormalization technique is always equal 0.198 (dimensionless). Moreover the critical concentration of MS is optimized using the spline approximation with the dataNESIA software. It is leading to a minimum disintegration time at 0.206, dimensionless, renormalized, which is very close to the experimental value of 0.198. According to the percolation theory, a minimum disintegration time corresponds to the formation of a continuous water-conducting cluster through the entire tablet. The critical volume fraction of an ‘infinite cluster’ that water can diffuse through the entire MA tablets are calculated with taking into account for the geometrical considerations between MS and MA particles based on random close packed (RCP) spheres system. The critical volume fraction of MS is calculated by the multiplication of critical concentration of MS and the solid fraction of MA tablets; which is within the range of 0.16 ± 0.01 (v/v). It is concluded that the critical volume fraction for three dimensional lattices is equal to 0.16 ± 0.01 (v/v); which is useful for the calculation of the critical concentration of starch based disintegrant in order to design the pharmaceutical tablet formulation based on scientific approach proposed by ICH Q8 guidance.
In addition, the disintegration behavior in the neighborhood of the percolation threshold is explained mathematically by the basic equation of the percolation theory, yielding a critical exponent q equal to 0.28 ± 0.06 (Quality of fit: r2 = 0.84). This value is close to the critical exponent for three dimensional lattices (q = 0.4). Thus, it is important, within a planned experimental design to optimize the disintegrant to take into account the percolation theory. However it has to be kept in mind that the determination of the percolation threshold and critical exponent does not give an answer about the absolute value of the disintegration time. Dissolution Simulation (DS) module, which is the one of F-CAD based on cellular automata algorithm is used to simulate the disintegration time of a MA tablet. Disintegration time of tablet is assumed as the time elapsed till the water is detected at the geometric center of the virtual tablet. Comparison of experimental disintegration time of MA tablet and computed specific time point for water to reach the geometric center of the tablet by using F-CAD software has been carried out and shown an acceptable correlation (Correlation coefficient: r = 0.81). The detailed evaluation of the data shows that there is still a need for optimization of F-CAD for the calculation of the disintegration time in order to achieve a similar or the same performance like in the prediction of the dissolution profile of a tablet formulation. It is concluded that F-CAD software is the only software so far, which is capable of computing the disintegration time of tablets. The software has a great potential to be improved and to be not only used for the safe prediction of the dissolution profile of a tablet formulation but also for a safe prediction of the disintegration time. Thus, such a software is one of the tools for the substitution of laboratory experiments for the purpose of the design and development of new pharmaceutical solid dosage forms. The replacement of expensive laboratory experiments by in-silico experiments is an important issue to reduce development costs and to comply with the requirements of ICH Q8 exploring the design space with response surface methodology. The results of this thesis show in addition that the application of percolation theory is a must in order to detect percolation thresholds. It is important to know the response surfaces close to the percolation threshold of sensitive tablet properties such as the disintegration time to get information about the robustness of the selected formulation. In this context one has to put the question forward if the application of percolation theory should be an integral part of the guidelines of ICH Q8 exploring the formulation design space
A Will from Miyazawa Kenji : Journey to the West, the Monkey King, and Dayu
Miyazawa Kenji (1896-1933) is a well-known author of children\u27s literature from and poet. He created many children\u27s literature and poet applying with his inexhaustible imagination. At the same time he often applied his rich culture for Chinese classics including not only the Four Books and Five Classics of Confucianism but also popular novel like Journey to the West to his works. In this paper we examined Miyazawa Kenji\u27s works and discussed meanings of Chinese classics for Miyazawa Kenji
Posuton Shuyojo ポストン収容所
A a travel journal written by Kenji Kawabe of his time away from the Poston camp, Arizona from May 9 through June 2, 1944. He visited the Granada camp in Colorado and Salt Lake and the Topaz camp in Utah, meeting his friends and going sightseeing and shopping.The Kuwahara Family Papers contains documentation of the Kuwahara family depicting the daily life and people incarcerated in the Poston camp in Arizona during World War II. Materials include: junior high school, high school, and camp community newsletters in both Japanese and English, a short travel journal written by Kenji Kaware of his time away from the Psoton camp, visiting the Granada camp in Colorado and Salt Lake and the Topaz camp in Utah, photographs of class groups, farm workers, and desert landscape, watercolor paintings of the camp facilities, and programs and booklets of the family and community reunions of the Poston incarceration camp
Does Trust Work in the Era of Distrust? Kenji Miyazawa and William James Give the Same Answer
This essay discusses ideas of Kenji Miyazawa that could help people of today rebuild confidence in themselves. Kenji held numerous ideas in common with great thinkers such as Fyodor Dostoevsky and William James. Kenji knew a great deal about the latest theories of natural science and psychology of his time. These were key sources of spiritual energy that enabled him to reexamine the relation between individual happiness and the happiness of the entire world. As the issue remains a major concern in our society, the author outlines Kenji's conclusion as to it
Does Trust Work in the Era of Distrust? Kenji Miyazawa and William James Give the Same Answer
This essay discusses ideas of Kenji Miyazawa that could help people of today rebuild confidence in themselves. Kenji held numerous ideas in common with great thinkers such as Fyodor Dostoevsky and William James. Kenji knew a great deal about the latest theories of natural science and psychology of his time. These were key sources of spiritual energy that enabled him to reexamine the relation between individual happiness and the happiness of the entire world. As the issue remains a major concern in our society, the author outlines Kenji's conclusion as to it
Radiocarbon age determinations on samples from Delta pingo (Fig. 3)
Radiocarbon age determinations on samples from Delta pingo (Fig. 3
Tab. 1: Results of chemical and isotope analyses
Tab. 1: Results of chemical and isotope analyse
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