1,723,923 research outputs found
Serum metabolomics strategy for understanding the therapeutic effects of Yin-Chen-Hao-Tang against Yanghuang syndrome
No full textThe purpose of the current research is to investigate the expression of endogenous biomarkers in Yanghuang syndrome mice and evaluate the clinical therapeutic effect of Yin-Chen-Hao-Tang.</p
Content Analysis of Media Reported American Baseball Player Wei-Yin Chen Shaping Sports Culture
No full text[[abstract]]This study is a media content analysis of Taiwanese baseball player Wei-Yin Chen who plays in the United States. His outstanding performance has played a role in the shaping of the cultural movement of baseball between Taiwan and the United States. Content from the United Daily News Network, Liberty Times and Apple Daily newspapers were consulted using the search term: "Wei-Yin Chen" during the post two-week periods of Chen’s first contract, first win, and second contract. A total of 444 news reports were found. The construction of six categories from literature review as points of analysis represented the basis for a semi-structured coding. First, individual identity value is driven by high salary of contract and Wei-Yin Chen’s charisma. Second, Wei-Yin Chen’s role on the team was recognized for his value and contribution to the team efforts with other players to produce the team's support and loyalty of fans. Third, concerning Taiwan's professional baseball and baseball operation managers’ reflection, in addition to nurture good players, the focus was on the cultivation of talent, senior baseball player's career development and players’ health care. Fourth, an economic ripple effect of Wei-Yin Chen on the sports industry was primarily from Chen’s media exposure and his high salary contract with MLB (Major League Baseball). Fifth, a social impact was on children who like to play baseball and see the opportunities to pursue their success in the sport. Sixth, after the globalization of value of Wei-Yin Chen to international sport, it is through the effects of the media to produce the impact of glocalization on Taiwanese sports culture
Recent Studies and Progression of Yin Chen Hao (茵陳蒿 Yīn Chén Hāo), a Long-term Used Traditional Chinese Medicine
No full textABSTRACTYin Chen Hao (Artemisia capillaris Thunb; 茵陳蒿 Yīn Chén Hāo) is a traditional Chinese medicine for treating hepatic disorders. This review provides recent pharmacological studies of Yin Chen Hao as well as some chemical constituents isolated from Yin Chen
MAKIAN DALAM FILM DĀNG NÁN RÉN LIÀN'ÀI SHÍ《当男人恋爱时》 KARYA YIN CHEN-HAO
Full text linkPenelitian ini mengkaji tentang bentuk dan fungsi makian dalam film Dāng Nánrén Liàn'ài Shí 《当男人恋爱时》Karya Yin Chen-Hao. Tujuan penelitian ini adalah mengetahui bentuk dan fungsi makian dalam film Dāng Nánrén Liàn'ài Shí 《当男人恋爱时》Karya Yin Chen-Hao berlandaskan pada teori Wijana (2004) dan Andersson (1985). Penelitian ini merupakan penelitian jenis kualitatif karena berfokus pada penggunaan makian dalam tuturan antartokoh, kemudian dianalisis dengan menggunakan pendekatan yang memungkinkan pemahaman mendalam mengenai bentuk dan fungsi yang terkandung dalam penuturan makian. Hasil analisis data yang ditemukan adalah bentuk makian yang ditemukan dalam film Dāng Nánrén Liàn'ài Shí《当男人恋爱时》 Karya Yin Chen-Hao mencakup lima dari delapan jenis makian menurut teori Wijana yaitu makian bentuk keadaan, binatang, bagian tubuh, kekerabatan, dan aktivitas. Makian jenis keadaan lebih banyak ditemukan yaitu sebanyak 28 data karena para tokoh sering menggunakan makian yang memiliki unsur keadaan. Makian bentuk makhluk halus, benda-benda, dan pekerjaan tidak ditemukan karena latar film yang sama sekali tidak berhubungan dengan dunia spiritual, tidak berhubungan dengan benda-benda menjijikkan, dan tidak ditemukannya pekerjaan yang melanggar hukum. Fungsi makian yang ditemukan dalam film Dāng Nánrén Liàn'ài Shí《当男人恋爱时》 Karya Yin Chen-Hao mencakup empat dari 5 fungsi makian menurut teori Andersson yaitu fungsi expletive, abusive, humoristic, dan habitual. Makian fungsi abusive lebih banyak ditemukan yaitu sebanyak 20 data karena penutur menggunakan makian untuk meluapkan emosi, mengejek, dan mengancam lawan tuturnya. Fungsi makian euphemistic tidak ditemukan karena para tokoh menuturkan makian secara abusive yang langsung menyerang ke petutur tanpa harus memperhalus makian yang sedang dituturkan
Quality evaluation of Yin Chen Hao Tang extract based on fingerprint chromatogram and simultaneous determination of five bioactive constituents
No full textA completely validated method based on HPLC coupled with photodiode array detector (HPLC-UV) was described for evaluating and controlling quality of Yin Chen Hao Tang extract (YCHTE). First, HPLC-UV fingerprint chromatogram of YCHTE was established for preliminarily elucidating amount and chromatographic trajectory of chemical constituents in YCHTE. Second, for the first time, five mainly bioactive constituents in YCHTE were simultaneously determined based on fingerprint chromatogram for furthermore controlling the quality of YCHTE quantitatively. The developed method was applied to analyze 12 batches of YCHTE samples which consisted of herbal drugs from different places of production, showed acceptable linearity, intraday (RSD <5%), interday precision (RSD <4.80%), and accuracy (RSD <2.80%). As a result, fingerprint chromatogram determined 15 representative general fingerprint peaks, and the fingerprint chromatogram resemblances are all better than 0.9996. The contents of five analytes in different batches of YCHTE samples do not indicate significant difference. So, it is concluded that the developed HPLC-UV method is a more fully validated and complete method for evaluating and controlling the quality of YCHTE
Simultaneous determination of 6,7-dimethylesculetin and geniposide in rat plasma and its application to pharmacokinetic studies of Yin Chen Hao Tang preparation
No full textA method for the rapid and simultaneous determination of 6,7-dimethylesculetin (CAS 120-08-1) and geniposide (CAS 24512-63-8) in rat plasma has been developed, using validated high performance liquid chromatography (HPLC) with solid phase extraction (SPE). The HPLC analysis was performed on a commercially available column (200 mm x 4.6 mm, 5 microm) with acetonitrile-methanol-0.1% aqueous formic acid as mobile phase and the UV detection at 343 nm and 238 nm for 6,7-dimethylesculetin and geniposide, respectively. The calibration curves for 6,7-dimethylesculetin and geniposide were linear over the range 0.4-25.6 microg/mL and 1.12-71.68 microg/mL, respectively. The lower limits of quantitation were 0.40 microg/ mL and 1.12 microg/mL, and the lower limits of detection were 0.06 microg/mL and 0.09 microg/ mL, respectively. The intra-day and inter-day precision for 6,7-dimethylesculetin and geniposide were < 5%, whereas the absolute recovery percentages were > 74%. A successful application of the developed HPLC analysis was demonstrated for the pharmacokinetic study of a Traditional Chinese Medicine formula of Yin Chen Hao Tang preparation
Simultaneous determination by UPLC-ESI-MS of scoparone, capillarisin, rhein, and emodin in rat urine after oral administration of Yin Chen Hao Tang preparation
No full textA simple, sensitive, and validated method was developed for simultaneous determination of scoparone, capillarisin, rhein, and emodin in rat urine by ultra-performance liquid chromatography/electrospray ionization quadruple time-of-flight mass spectrometry (UPLC-MS). The urinary samples were analyzed on an Acquity UPLC BEH C18 1.7 microm 2.1x50 mm column. Scoparone, capillarisin, rhein, and emodin in rat urine were simultaneously analyzed with good separation. The lower limits of detection were 6.0, 9.0, 7.0, and 3.0 ng/mL, and the lower limits of quantification were 20.0, 33.0, 24.0, and 12.0 ng/mL for scoparone, capillarisin, rhein, and emodin, respectively. The intra- and inter-day precisions (RSD) were less than 9%. The intra- and inter-accuracies were found to be in the range of 94.14-104.54% for scoparone, 101.72-107.34% for capillarisin, 95.24-103.59% for rhein, and 101.32-107.82% for emodin at three concentration levels. The absolute recoveries for scoparone, capillarisin, rhein, and emodin were not less than 77.0%. The developed method has been applied to determine scoparone, capillarisin, rhein, and emodin in rat urine after oral administration of Yin Chen Hao Tang preparation, a traditional Chinese medicine formulation widely used in China for treatment of jaundice and liver disorders
Analysis of the constituents in the rat plasma after oral administration of Yin Chen Hao Tang by UPLC/Q-TOF-MS/MS
No full textA UPLC/Q-TOF-MS/MS method for analyzing the constituents in rat plasma after oral administration of Yin Chen Hao Tang (YCHT), a traditional Chinese medical formula, has been established. The UPLC/MS fingerprints of the samples were established first in vitro and in vivo, with 45 compounds in YCHT and 21 compounds in rat plasma after oral administration of YCHT were detected. Of the 45 detected compounds in vitro, 30 were identified, and all of the 21 compounds detected in rat plasma were identified either by comparing the retention time and mass spectrometry data with that of reference compounds or by mass spectrometry analysis and retrieving the reference literatures. Of the identified 21 compounds in rat plasma, 19 were the original form of compounds absorbed from the 45 detected compounds in vitro, 2 were the metabolites of the compounds existed in YCHT. It is concluded that a rapid and validated method has been developed based on UPLC-MS/MS, which shows high sensitivity and resolution that is more suitable for identifying the bioactive constituents in plasma after oral administration of Chinese herbal medicines, and provides helpful chemical information for further pharmacology and active mechanism research on the Chinese medical formula
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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