14 research outputs found
Can the C-reactive protein-to-plasma albumin ratio be an alternative scoring to show mortality and morbidity in patients with colorectal cancer?
No full textPreface of Symposium “Modern and Classical Optimization Techniques in Multi Disciplinary Studies”
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A Facile Method for the Preparation of Poly(4-vinylpyridine) Nanoparticles and their Characterization
No full textSubmicron size particles were synthesized from 4-vinylpyridine (4-VP) using an oil-in-water emulsion system. Divinyl benzene (DVB) and ethylene glycol dimethacrylate (EGDMA) were utilized as crosslinkers for the synthesis of p(4-VP) hydrogel nanoparticles in sodium dodecyl sulfate (SDS) surfactant systems. Characterization of the particles was made by transmission electron microscopy (TEM) and dynamic light scattering (DLS) methods. To render a positive charge, p(4-VP) particles were reacted with 1-bromo butane (1-BB).Tulane UniversityThe author is grateful for the financial support provided by Prof. Dr. Vijay T. John of Tulane University
Mortality prediction ability of phycians in intensive care units of Turkey (MOPAP)
No full textKUCUK, Ahmet Oguzhan/0000-0002-6993-0519; Yalcinsoy, Murat/0000-0003-3407-7359; KUCUK, Mehtap PEHLIVANLAR/0000-0003-2247-4074; Sahiner, Yeliz/0000-0002-5377-3870Introduction: Intensive care physicians are increasingly involved in decision making about the prognosis of intensive care unit ICU patients. With this study; we aimed to evaluate the power of clinician foresight at prediction of mortality in patient at triage to intensive care and patient follow-up. Materials and Methods: This study was conducted in ICUs located in various geographical regions of Turkey between January 1, 2017-April 30, 2017. The clinical research was planned as observational, multicenter, cross-sectional. Results: A total of 1169 intubated patients were followed in 37 different ICU. At the beginning of the follow-up we asked the physician who will follow the patient in the ICU to give a score for the probability of survival of the patients. Scoring included a total of 6 scores from 0 to 5, with the "0" the worst probability "5" being the best. According to this distribution, only 1 (0.9%) of 113 patients who were given 0 points survived. Three (6.1%) of 49 with the best score of 5 died. Survival rates were significantly different in each score group (r: -0.488; p< 0.001). After the combined mortality estimation scores based on the clinical observations of the physicians (0 and 1 point score was combined as non-survive, 4 and 5 score was combined as survived) 320 of the 545 patients were estimated to be dead and 225 were predicted survival. Sensitivity and spesifity of scoring system to predict mortality was 91.56% (95% Cl: 87.96-94.37), 76.89% (95% CI: 70.82-82.23) respectively. Conclusion: In this study, we concluded that the physicians who follow the patients in the ICU can predict the poor prognosis at the time of admission and the high mortality rate. The physician's opinion on mortality estimation should be considered in intensive care mortality scoring in addition to other laboratory and clinical parameters
The effects of virtual reality glasses and external cold and vibration on procedural pain and anxiety in children during venous phlebotomy: randomized controlled trial
No full textNeedle-related procedures are among the most feared and painful experiences reported by children and their parent. For this reason, use of effective methods of pain relief is very important during phlebotomy procedures in children. The aim of this study is to research two different distraction methods (external cold and vibration-Buzzy + virtual reality) on relief of procedural pain and anxiety in children during phlebotomy. This study is a prospective, randomized and controlled trial. Sample of the study consisted of a total of 119 children who met the sample selection criteria. Children aged 7 to 12 years who required phlebotomy were divided into three groups: buzzy (n = 40), virtual reality (n = 40), and control (n = 39). Data were collected using the information form, Wong–Baker FACES Pain Rating Scale, and Children’s Fear Scale. In the study, 119 children [girls n = 59 (49.6%), boys n = 60 (50.4%)] were included. The children’s pain levels were assessed and reported by the parents and observers and the children themselves who self-reported using Wong–Baker FACES. The children’s anxiety levels were also assessed using the Children’s Fear Scale. A significant difference was found between the groups in terms of the parent-reported and observer-reported assessments (p 0.05). According to the parent-reported and observer-reported assessments, a significant difference was found between procedural anxiety levels. VR is more effective than external cold and vibration-Buzzy in reducing pain during phlebotomy and should be preferred as the first choice. © 2022, The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.The authors would like to thank all administrators, patients, and staff nurses who helped the researcher to conduct this study
The end-tidal desflurane concentration for smooth removal of the laryngeal mask airway in anaesthetised adults
No full textThe Use of Low-Quality Cotton-Derived Cellulose Films as Templates for In Situ Conductive Polymer Synthesis as Promising Biomaterials in Biomedical Applications
No full text© 2024 The Author(s). Macromolecular Materials and Engineering published by Wiley-VCH GmbH. cc-byHere, the use of cellulose films (CFs) produced from low-quality cotton is reported as a template for in situ synthesis of well-known conductive polymers, e.g., polyaniline (PANI) and polypyrrole (PPY) via oxidative polymerization. Three successive monomer loading/polymerization cycles of aniline (ANI) and pyrrole (PY) within CFs as PANI@CF or PPY@CF are carried out to increase the amount of conductive polymer content. The contact angle (CA) for three times ANI and PPY loaded and polymerized CFs as 3PANI@CF and 3PPY@CF are determined as 26.3±2.8 and 42.3±0.6 degrees, respectively. As the electrical conductivity is increased with increased number of conductive polymer synthesis within CF, the higher conductivity values, 3×10−4±8.1×10−5 S.cm−1 and 2.1×10−3±5.8×10−4 S.cm−1, respectively are measured for 3PANI@CF and 3PPY@CF composites. It is found that PANI@CF composites are hemolytic, whereas PPY@CF composites are not at 1 mg mL−1 concentrations. All PPY@CF composites exhibit better biocompatibility than PANI@CF composites on L929 fibroblast cells with more than 70±8% viability at 1 mg of CF-based conductive polymer composites. Moreover, MIC and MBC values of 3PPY@CF composites for Escherichia coli (ATCC8739) and Staphylococcus aureus (ATCC6538) are determined as 2.5 and 5.0 mg.mL−1, whereas these values are estimated as 5 and 10 mg.mL−1 for Candida albicans (ATCC10231)
Poly(vinyl amine) microparticles derived from N-Vinylformamide and their versatile use
No full textCationic polymers with primary amine groups that can easily be functionalized or coupled with substrates by complexation or hydrogen bonding are especially advantageous in preparing particles for biomedical applications. Poly(vinyl amine) (PVAm) is a cationic polyelectrolyte containing the highest number of primary amine groups among any other polymers. Here, we introduce a general method in synthesizing PVAm microparticles via a surfactant-free water-in-oil emulsion technique using cyclohexane as the oil phase and aqueous PVAm solution as the dispersed phase. PVAm particles were prepared to employ two different bifunctional chemical crosslinkers, divinyl sulfone (DVS) and poly(ethylene glycol) diglycidyl ether (PEGGE). The prepared particles were further treated with HCl to protonate the amine groups of PVAm within particles. The effect of crosslinker types and pH on the hydrolytic degradation of PVAm particles were also investigated at three different solution pHs, 5.4, 7.4, and 9, to simulate the skin, blood, and intestinal pH environments, respectively. The blood compatibility of the PVAm particles was evaluated by in vitro hemolysis and blood clotting assays. Furthermore, antifungal and antibacterial efficacy of PVAm-based particles and their protonated forms were tested against C. albicans yeast and E. coli, S. aureus, B. subtilis, and P. aeruginosa bacterial strains. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature
