1,721,002 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Prospective analysis between surgical and clinical treatments for mesial temporal lobe epilepsytemporal : Prospective analysis between surgical and clinical treatments for mesial temporal lobe epilepsytemporal

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    Orientadores: Fernando Cendes, Helder TedeschiTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciencias MedicasResumo: Objetivo: A cirurgia para pacientes com epilepsia de lobo temporal mesial refratária oferece um controle de crises para aproximadamente 70% dos pacientes. Neste estudo comparamos a eficácia entre o tratamento clínico e cirúrgico e investigamos a relação entre as alterações estruturais (atrofia de substância branca, SB e cinzenta, SC) nas imagens de ressonância magnética (RM) pré-operatórias e o resultado cirúrgico; bem como evidências estruturais de neuroplasticidade nas imagens de RM pós-operatórias. Métodos: Realizamos uma curva de sobrevivência de Kaplan-Meier para comparar a eficácia entre os dois tipos de tratamento, para o grupo clínico (85 pacientes, 30 mulheres) e grupo cirúrgico (46 pacientes, 16 mulheres). Avaliamos as imagens de RM através da técnica de Morfometria Baseada em Voxel com o software SPM2 (Statistical Parametric Mapping)/MATLAB 7.0, comparando pacientes com indivíduos normais através de um Teste-T. Para essa análise dividimos os pacientes operados em grupos de acordo com o controle de crises obtido. Para investigar as alterações plásticas pós-operatórias realizamos um teste-T pareado entre as imagens pré e pós-operatórias. Resultados: A análise de sobrevivência confirmou a superioridade do tratamento cirúrgico (84% de pacientes controlados) em longo razo em comparação ao tratamento medicamentoso (7% de pacientes controlados), p< 0,001. Os pacientes com melhor resultado cirúrgico apresentavam um padrão restrito de atrofia de SC em comparação aos pacientes com crises após a cirurgia. Apenas os pacientes controlados tiveram evidências de recuperação de SB e SC após a cirurgia. Conclusão: A cirurgia oferece um melhor controle de crises que o tratamento medicamentoso e a chance de recuperar áreas com atrofia de SB e SC.Abstract: Objective: Surgery for refractory mesial temporal lobe epilepsy (MTLE) generally offers good seizure control for approximately 70% of patients. In this study we compared the efficacy between surgical and clinical treatments and investigated the relationship between pre-operative structural abnormalities (white matter and grey matter atrophy) and surgical outcome. We also investigated the structural evidences of brain plasticity on post-operative MRI scans. Methods: We performed Kaplan-Meier survival analysis to compare the efficacy between surgical and medical groups. Clinical group included 85 patients (30 women) and the surgical group included 46 patients (16 women). We applied Voxel Based Morphometry technique on SPM2 (Statistical Parametric Mapping)/MATLAB 7.0 and compared patients with normal individuals with T-Test. For this analysis we separated patients according to post-operative surgical control. In order to investigate plastic changes after surgery we performed paired T-Test between pre and postoperative MR scans. Results: Survival analysis confirmed the superiority of surgical treatment for long-term seizure control (seizure control in 84% of patients) compared to medical treatment (seizure control in 7% of patients), p<0.001. Patients with better seizure control presented a restricted pattern of Grey matter atrophy, compared to patients with poorer seizure control which presented a widespread pattern of Grey matter atrophy. Our analysis showed that only patients with good seizure control presented structural evidences of white matter and grey matter recovery after surgery. Conclusion: Surgical treatment offers better chances of seizure control for refractory MTLE as well as the opportunity of relative white matter and grey matter recovery.DoutoradoNeurologiaDoutor em Ciências Médica

    Estudo comparativo entre os tratamentos clinico e cirurgico para pacientes com epilepsia do lobo temporal mesial

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    Orientador: Helder TedeschiDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciências MédicasResumo: A epilepsia é uma doença crônica que acomete 0,5% a 2% da população em geral, sendo considerada a segunda patologia neurológica mais freqüente. A epilepsia de lobo temporal mesial (ELTM) com atrofia hipocampal é a forma mais freqüente das epilepsias parciais refratárias ao tratamento medicamentoso. Nestes pacientes, o tratamento cirúrgico é capaz de proporcionar uma redução da freqüência ou o controle total de crises. Com o objetivo de comparar a eficácia dos tratamentos cirúrgico e clínico realizamos um estudo prospectivo com 26 pacientes com ELTM que foram submetidos a tratamento cirúrgico e 75 pacientes com ELTM submetidos a tratamento medicamentoso entre agosto de 2002 e outubro de 2004 . Todos os pacientes apresentavam critérios de refratariedade, ou seja, controle inadequado de crises parciais com uso em doses máximas toleradas de pelo menos duas drogas antiepilépticas, durante pelo menos um ano. Utilizamos a análise de curva de sobrevivência de Kaplan-Meier em função do tempo de recorrência das crises para obter o intervalo de confiança dos pacientes sem crises e o teste log-rank para comparação do estado de controle de crises entre os grupos. A proporção acumulada dos pacientes sem crise (classe IA de Engel) foi maior no grupo submetido ao tratamento cirúrgico (73.1%) comparando-se com o grupo clínico (12%) (p<0.0001). No grupo cirúrgico, 2 de 26 pacientes (7.7%) apresentaram alterações neurológicas transitórias e 2 dos 26 (7.7%), alterações neurológicas permanentes relacionados ao procedimento cirúrgico. No grupo clínico, sete pacientes (9.3%) apresentaram eventos adversos graves durante o seguimento, tais como queimaduras e estado de mal epiléptico. O tratamento cirúrgico para ELTM refratária ao tratamento clínico prévio com duas DAEs foi mais eficiente que o tratamento clínico, incluindo novas tentativas de mono ou politerapiaAbstract: Epilepsy is a chronic disease that affects 0.5% to 2% of the general population, and is considered the second most frequent neurological condition in outpatient clinics. Mesial temporal lobe epilepsy (MTLE) associated to hippocampal sclerosis is the most frequent type of partial epilepsy in adult. A significant proportion of these patients do not respond to antiepileptic drugs (AEDs). For patients with MTLE and refractory seizures, surgery is considered an efficient treatment option. We prospectively studied 26 patients with MTLE who underwent surgical treatment and 75 patients with MTLE who underwent medical treatment between August 2002 and October 2004. All patients failed to achieve seizure control with at least two first line AED for partial seizures before entering the study. We used Kaplan-Meier survival analysis as a function of time of seizure recurrence to obtain estimates of 95% confident interval of seizure freedom and log-rank test to compare the status of seizure control between the two groups. The cumulative proportion of patients free of all seizures (Engel¿s class IA) was higher in the surgical group (73.1%) compared to the clinical group (12%) (p<0.0001). In the surgical group, 2 of 26 patients (7.7%) had transient adverse effects and 2 of 26 patients (7.7%) had a permanent deficit related to the surgical procedure. In the clinical group 7 patients had (9.3%) major adverse events during follow-up, including burns and status epilepticus. Surgical treatment for patients with MTLE who failed to achieve seizure control with two previous AED regimens was more efficient than medical treatment with further trials of AEDMestradoNeurologiaMestre em Ciências Médica

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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