6,279 research outputs found
Systematic investigation of gastrointestinal diseases in China (SILC): validation of survey methodology
Background: Symptom-based surveys suggest that the prevalence of gastrointestinal diseases is lower in China than in Western countries. The aim of this study was to validate a methodology for the epidemiological investigation of gastrointestinal symptoms and endoscopic findings in China. Methods: A randomized, stratified, multi-stage sampling methodology was used to select 18 000 adults aged 18-80 years from Shanghai, Beijing, Xi'an, Wuhan and Guangzhou. Participants from Shanghai were invited to provide blood samples and undergo upper gastrointestinal endoscopy. All participants completed Chinese versions of the Reflux Disease Questionnaire (RDQ) and the modified Rome II questionnaire; 20% were also invited to complete the 36-item Short Form Health Survey (SF-36) and Epworth Sleepiness Scale (ESS). The psychometric properties of the questionnaires were evaluated statistically. Results: The study was completed by 16 091 individuals (response rate: 89.4%), with 3219 (89.4% of those invited) completing the SF-36 and ESS. All 3153 participants in Shanghai provided blood samples and 1030 (32.7%) underwent endoscopy. Cronbach's alpha coefficients were 0.89, 0.89, 0.80 and 0.91, respectively, for the RDQ, modified Rome II questionnaire, ESS and SF-36, supporting internal consistency. Factor analysis supported construct validity of all questionnaire dimensions except SF-36 psychosocial dimensions. Conclusion: This population-based study has great potential to characterize the relationship between gastrointestinal symptoms and endoscopic findings in China.Xiaoyan Yan, Rui Wang, Yanfang Zhao, Xiuqiang Ma, Jiqian Fang, Hong Yan, Xiaoping Kang, Ping Yin, Yuantao Hao, Qiang Li, John Dent, Joseph Sung, Duowu Zou, Saga Johansson, Katarina Halling, Wenbin Liu and Jia H
The SF-36: a simple, effective measure of mobility disability for epidemiological studies
BackgroundMobility disability is a major problem in older people. Numerous scales exist for the measurement of disability but often these do not permit comparisons between study groups. The physical functioning (PF) domain of the established and widely used Short Form-36 (SF-36) questionnaire asks about limitations on ten mobility activities.ObjectivesTo describe prevalence of mobility disability in an elderly population, investigate the validity of the SF-36 PF score as a measure of mobility disability, and to establish age and sex specific norms for the PF score.MethodsWe explored relationships between the SF-36 PF score and objectively measured physical performance variables among 349 men and 280 women, 59-72 years of age, who participated in the Hertfordshire Cohort Study (HCS). Normative data were derived from the Health Survey for England (HSE) 1996.Results32% of men and 46% of women had at least some limitation in PF scale items. Poor SF-36 PF scores (lowest fifth of the gender-specific distribution) were related to: lower grip strength; longer timed-up-and-go, 3m walk, and chair rises test times in men and women; and lower quadriceps peak torque in women but not men. HSE normative data showed that median PF scores declined with increasing age in men and women.ConclusionOur results are consistent with the SF-36 PF score being a valid measure of mobility disability in epidemiological studies. This approach might be a first step towards enabling simple comparisons of prevalence of mobility disability between different studies of older people. The SF-36 PF score could usefully complement existing detailed schemes for classification of disability and it now requires validation against them
SF Gospel: Blog contents, 2006-2015
SF Gospel (2006-2015) was a blog exploring religious and theological themes in science fiction and popular culture by Gabriel Mckee, author of The Gospel According to Science Fiction. The primary PDF contains the textual content of the blog, along with most images that accompanied the original posts. The appendix PDF contains guest posts written by Mckee for other blogs and websites (including SF Signal, Holy Heroes, Nerve.com, and Religion Dispatches) during the course of SF Gospel's existence
Additional Files for Master Thesis "Framing Diets for Policy to Fight Climate Change"
Additional files for Master Thesis "Framing Diets for Policy to Fight Climate Change: Using video messages to measure the effect of goal framing on attitudes and intentions to reduce beef and dairy consumption to fight climate change"
Datasets
Intervention Framed Videos
Written within the M.Sc. Public Policy and Human Development at Maastricht University MGSoG/UNU-MERIT
Author: Sten Ritterfeld
Supervisor: Michelle González Amador
Submission date: July 12, 202
Sf-SR-C acts as the receptor for Vip3Aa <i>ex vivo</i>.
(A) qRT-PCR analysis of the relative transcript levels of SR genes in the cell lines of Sf9, Sf-pIZT, Sf-SRi1 and Sf-SRi2; Data are expressed as the mean ± SD from three independent experiments; ns, non-significant; *** P < 0.001; one-way ANOVA with Dunnett’s method. (B) Cell mortality of different cell lines (Sf9, Sf-pIZT, Sf-SRi1 and Sf-SRi2) exposed to 50 μg/mL of Vip3Aa for 48 h. Data are expressed as the mean ± SD from three independent experiments; ns, non-significant; ** P < 0.01; one-way ANOVA with Duncan method. (C) Confocal microscopy sections showing the localization of Vip3Aa-RFP (red) and Sf-SR-C (green) in Sf9 cells. The anti-Sf-SR-C-N polyclonal antibody and Alexa Fluor 488-conjugated anti-rabbit antibody were used to show the location of Sf-SR-C in Sf9 cells. Anti-GST polyclonal antibodies were used as the control. Arrowheads point to co-localization between Vip3Aa-RFP and Sf-SR-C. Nuclei are stained with DAPI (blue). Scale bar, 10 μm. (D) S2 cells were transfected with Sf-SR-C or Sf-S2. 48 h after transfection, cells were exposed to Vip3Aa-RFP or RFP (red), fixed, and then immunostained with Dylight 488-conjugated anti-V5 antibodies (green). Nuclei are stained with DAPI (blue). Scale bar, 10 μm. (E) Cell viability of different S2 cell lines (S2, S2-Sf-S2 and S2-Sf-SR-C) exposed to 25 μg/mL of Vip3Aa for 48 h (The transfection efficiency was about 30%). Data are expressed as the mean ± SD from three independent experiments; ns, non-significant; ** P < 0.01; one-way ANOVA with Duncan method.</p
Sf-SR-C mediates the internalization of Vip3Aa.
(A) Confocal microscopy sections showing Vip3Aa-RFP dots in the Sf9 cells. The cells were separately incubated with purified anti-Sf-SR-C-N polyclonal antibodies and anti-GST polyclonal antibodies for 1 h and the cells were then co-incubated with Vip3Aa-RFP (4.5μg/ml) for another 6 h. Nuclei are stained with DAPI (blue) and cell membrane are stained with FITC-phalloidin (green). Scale bar, 10 μm. (B) Confocal images showing Vip3Aa-RFP dots in the Sf9 cells. The cells were treated by Vip3Aa-RFP (4.5μg/ml) combined with an excess of GST-SR-F-1 and GST-SR-F-2 (20-fold) respectively. Nuclei are stained with DAPI (blue) and cell membrane are stained with FITC-phalloidin (green). Scale bar, 10 μm. (C) Confocal images showing Vip3Aa-RFP dots in the Sf-pIZT, Sf-SRi1 and Sf-SRi1 cells after incubating with Vip3Aa-RFP (4.5μg/ml) for 6 h. Nuclei are stained with DAPI (blue). Scale bar, 10 μm. (D) Quantification of the number of conspicuous Vip3Aa-RFP dots in Sf9 cells of (A), (B) and (C) in a blind fashion (n = 100 cells per sample). Data are expressed as the mean ± SD from three independent experiments; ns, non-significant; *** P < 0.001; one-way ANOVA using Duncan method.</p
SF-36 outcomes and cognition in blood donation of blood donors with different characteristics.
SF-36 outcomes and cognition in blood donation of blood donors with different characteristics.</p
NSCT-SF-PCNN-ImageFusion-Toolbox
Matlab toolbox,论文的代码, 《非降采样Contourlet域内空间频率激励的PCNN图像融合算法》屈小波, 闫敬文, 肖弘智, 朱自谦Matlab Image Fusion Toolbox for Image Fusion Algorithm Based on Spatial Frequency-Motivated Pulse Coupled Neural Networks in Nonsubsampled Contourlet Transform Domain.
You can download this toolbox at http://quxiaobo.8866.org/project/NSCT_SF_PCNN/NSCT-SF-PCNN-ImageFusion-Toolbox.zip
This toolbox contains Matlab files that implement the image fusion algorithms described in paper
Qu Xiao-Bo, YAN Jing-Wen, XIAO Hong-Zhi, ZHU Zi-Qian. Image Fusion Algorithm Based on Spatial Frequency-Motivated Pulse Coupled Neural Networks in Nonsubsampled Contourlet Transform Domain. Acta Automatica Sinica, Vol.34, No.12, pp: 1508-1514.Dec.2008.
You can download the paper at the following links:
http://www.aas.net.cn/qikan/manage/wenzhang/081208.pdf
Or
http://dspace.xmu.edu.cn/dspace/bitstream/2288/15459/1/2007-1182.pdf
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If you use the code, please cite the paper as follows:
% References:
[1] Qu Xiao-Bo, YAN Jing-Wen, XIAO Hong-Zhi, ZHU Zi-Qian. Image Fusion Algorithm Based on Spatial Frequency-Motivated Pulse Coupled Neural Networks in Nonsubsampled Contourlet Transform Domain. Acta Automatica Sinica, Vol.34, No.12, pp: 1508-1514.Dec.2008.
(Check http://quxiaobo.8866.org or http://quxiaobo.go.8866.org, http://quxiaobo.blog.edu.cn or http://naec.stu.edu.cn for these and other related papers.)
%=============================================================
QU Xiao-BO,
Xiamen University in P.R.China, April 2009.
% ---------
% Author: Qu Xiao-Bo Aug.28,2008
% Postal address:
% Ro0m 509, Scientific Research Building # 2,Haiyun Campus, Xiamen University,Xiamen,Fujian, P. R. China, 361005
% Website: http://quxiaobo.8866.org or http://quxiaobo.go.8866.org
%=============================================================
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You have to other toolbox required:
1.PCNN toolbox at
http://quxiaobo.8866.org/project/PCNN/PCNN_toolbox.rar
or http://dspace.xmu.edu.cn/dspace/bitstream/2288/15579/1/PCNN_toolbox.rar
2. FusionEvalution toolbox at http://quxiaobo.8866.org/project/FusionEvaluation/FusionEvaluation.rar
or http://dspace.xmu.edu.cn/dspace/bitstream/2288/16979/1/FusionEvaluation.rar
3.NSCT toolbox at
http://www.mathworks.com/matlabcentral/fileexchange/10049
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Acknowledgement
1. This code is copyright and is supplied free of charge for research
purposes only. In return for supplying the code, all I ask is that, if
you use the algorithms, you give due reference to this work in any
papers that you write. If the applications are good, I would be
very interested in collaboration. I accept no liability arising from use
of these algorithms.
2. Thanks Arthur Cunha for sharing his nsct toolbox for our image fusion algorithmSupported by Navigation Science Foundation of P. R. China
(05F07001) and National Natural Science Foundation of P. R. China
(60472081
Additional Files for Master Thesis "Framing Diets for Policy to Fight Climate Change"
Additional files for Master Thesis "Framing Diets for Policy to Fight Climate Change: Using video messages to measure the effect of goal framing on attitudes and intentions to reduce beef and dairy consumption to fight climate change"
Datasets
Intervention Framed Videos
Written within the M.Sc. Public Policy and Human Development at Maastricht University MGSoG/UNU-MERIT
Author: Sten Ritterfeld
Supervisor: Michelle González Amador
Submission date: July 12, 202
Decreased number of locules and pericarp cell layers underlie smaller and ovoid fruit in tomato smaller fruit (sf) mutant
Fruit size and shape are the prime criteria for domestication and improvement of tomato. The varying sizes and shapes of tomato fruits further signify their importance as agronomic traits. Here, we characterized a tomato mutant, smaller fruit (sf), which bears relatively small and ovoid fruits compared with large and flat fruits of wild-type (WT). Phenotypic measurements and histological analyses revealed that fruit diameter but not fruit length of sf mutant decreased compared with that of WT. This phenotypic change was attributed to significant decreases in locule number and pericarp cell layers in transverse direction, which resulted in the transition of fruit shape from flat in WT to ovoid in sf. Comparison of transcriptomes of ovaries between sf and WT by RNA-Seq identified 2,596 differentially expressed genes, in which 1,737 genes significantly up-regulated and 859 genes dramatically down-regulated in the sf ovary. Further analyses confirmed that some genes, such as CRCa, CNRs, CYCs, WUS, SUNs, OFRs, CDKs, participate in regulation of fruit size and shape of sf mutant. Thus, our study adds a new genetic resource regarding fruit size and shape of tomato, and provides a valuable basis for dissecting molecular regulation of small and ovoid fruit of sf mutant.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
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