254 research outputs found
Effects of rewarming therapies on outcomes in accidental hypothermia: A secondary analysis of a multicenter prospective study
No full text弘前大学博士（医学）Author(s): Kana Sugiyama, Osamu Nomura, Jin Irie, Yoshiya Ishizawa, Shuhei Takauji, Mineji Hayakawa, Yoshinori Tamada, Hiroyuki Hanad
The report of private exhibition "Shuhei Otsuka exhibition at Atsugi art gallery". - A reflection on the relationship between art education and private exhibition -
No full text本稿では2014 年に新設された「あつぎアートギャラリー」での個展開催を通し、厚木市民はじめ、学生や教職員、その他多くの方々に、テラコッタ彫刻作品鑑賞の機会を提供する事によって、美術に親しみ愛好する心情を育てる事を試みた。そして作家自身が作品を顧みることによって、今後の方向性について考える機会とした。An exhibition was held at an established newly "Atsugi art gallery" in 2014. I tried to enjoy fine arts and bring up loved sentiment by making the chance to appreciate terracotta sculpture works to citizen in Atsugi,students of Shohoku junior college, a teaching staff member of college and many persons. And another purpose is the case that an author reconsiders the former work and considers directionality ofthe next production.2KJ00009869519departmental bulletin pape
Mikami-Weinstein Type Theorem for Cosymplectic Groupoid Actions
No full textThe Mikami-Weinstein theorem is a generalization of the classical Marsden-Weinstein-Meyer symplectic reduction theorem to the case of symplectic groupoid actions. In this paper, we introduce the notion of a cosymplectic groupoid action on a cosymplectic manifold and prove a theorem that is a natural analogue of the Mikami-Weinstein theorem.The author is grateful to R. Goto for his encouragement. The author also thanks N. Ikeda for useful conversations. He greatly appreciates the suggestions of the anonymous referees, which considerably improved the presentation. This work was supported by JSPS KAKENHI Grant Number JP23KJ1487
Fabrication of silicon thin films with defects below detection limit of electron spin resonance for solar cells by high-speed zone-melting crystallization of amorphous silicon
No full textPhoto Responsible Soft nano Gel - Regulation of siRNA-[1]
No full textWe have developed photo responsible nano gels containing various functional molecules.[2-3] By means of endocytosis, the soft nano gels are internalized by cells, where the encapsulated molecules retain their functionality for more than 3 days. The encapsulated molecules are released and reactivated by UV irradiation. Animal experiments revealed that the acute toxicity of the nano gels is negligible and interestingly the nano gels were excreted in urine within a day.[4] Because the encapsulated molecules are trapped physically by the mesh structure of the nano gels, we expected that there would be few limitations to the types of molecules that could be encapsulated and controlled by means of this technique. Although RNA is chemically unstable, we expected that it could be delivered, via the nano gels, to the cytosol, where it could be released and activated by light stimulation.
In this study, we prepared nano gel of around 120 nm containing siRNA by mixing four-arm monomers and siRNA. The siRNA containing nano gels were internalized by human ovarian cancer cells (SKOV3-Luc) and were then released by irradiation of the cells with light. Gene-specific silencing was observed approximately 8–48 h after irradiation, as indicated by a luciferase assay. (Fig.1)
Because this technique allows for spatiotemporal regulation of target gene expression within cells by means of a noninvasive external stimulus (light for 30 s), we expect this technique to be useful for basic research and clinical applications such as gene therapy for cancers, genetic disorders, and macular degeneration.
\nReferences:
1) Shuhei Murayama, Petra Kos, Kanjiro Miyata, Kazunori Kataoka, Ernst Wagner, Masaru Kato, Macromolecular Bioscience, just accepted
2) Shuhei Murayama, Taihei Nishiyama, Kaihei Takagi, Fumi Ishizuka, Tomofumi Santa, Masaru Kato, Chem. Commun., 48, 11461-11463, (2012).
3) Shuhei Murayama, Baowei Su, Kohki Okabe, Akihiro Kishimura, Kensuke Osada, Masayuki Miura, Takashi Funatsu, Kazunori Kataoka, Masaru Kato, Chem. Commun., 48, 8380-8382, (2012).
4) Shuhei Murayama, Jun-ichiro Jo, Yuka Shibata, Kun Liang, Tomofumi Santa, Tsuneo Saga, Ichio Aoki, Masaru Kato, J. Mater. Chem. B, 1, 4932-4938, (2013).
\nKeywords: gene delivery, nano gel, photocontrol, spatiotemporal regulation, siRNA
Corresponding author*: [email protected] 15th IUMRS-International Conference in Asia(IUMRS-ICA 2014)conference objec
Scale-free property of local-world networks and their community structures
No full textThe scale-free property and community structures of complex networks formed by local events have been studied theoretically, numerically, and empirically. We showed analytically and numerically that the degree distribution function P(k) of the local-world evolving network exhibits a crossover from an exponential to power-law form by increasing the local-world size M. For M much larger than the crossover local-world size Mco, the distribution function P(k) has a power-law form for any degree k(>> 1). Below Mco, however, P(k) obeys a power law for 1 > kco. The crossover size Mco and the crossover degree kco have been also elucidated. In addition, we constructed the drug prescription network (DPN) as a real local-world network, in which the local-world subsets are definitely specified, to reveal how the local-world nature affects properties of real-world networks. We found that the community structure of the DPN strongly correlates with the local worlds
A generalization of APN functions for odd characteristic
No full textAlmost perfect nonlinear (APN) functions on finite fields of characteristic two have been studied by many researchers. Such functions have useful properties and applications in cryptography, finite geometries and so on. However, APN functions on finite fields of odd characteristic do not satisfy desired properties. In this paper, we modify the definition of APN function in the case of odd characteristic, and study its properties. (C) 2017 Elsevier Inc. All rights reserved
Statistical properties of weighted complex networks characterized by metaweights
No full textWe propose several characterizations of weighted complex networks by incorporating the concept of metaweight into the clustering coefficient, degree correlation, and module decomposition. These incorporations make it possible to describe weighted networks depending on how strongly we emphasize weights. Using some applications to real-world weighted networks, we demonstrate that the proposed approach provides rich information that was inaccessible by previous analyses such as the degree correlation for a specific magnitude of weights or the community structure under controlling the importance of roles of the topology and weights
Nonlinear frequency-asymmetric optical response in chiral systems
No full textWe report our theoretical results on the emergence of a nonlinear frequency-asymmetric optical response characteristic of chiral crystal systems with neither spatial inversion symmetry nor mirror symmetry. Based on the group theoretical analysis, we show that the chirality-related second-order nonlinear optical response occurs for two different input frequencies when the low-energy model Hamiltonian includes a time-reversal-even pseudoscalar quantity, i.e., the electric toroidal monopole. We demonstrate its emergence by investigating a fundamental microscopic model with the chiral-type antisymmetric spin-orbit interaction on a simple cubic lattice. By analyzing the behavior of nonlinear optical conductivity based on the Kubo formula, we find that the response is largely enhanced when one of the frequencies is set to 0 and the other is set to a resonant frequency. We also discuss the relaxation time dependence of the response
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