4,964 research outputs found
Social Metadata for Libraries, Archives and Museums. Part 3: Recommendations and Readings
No full textRecommendations on social metadata features most relevant to libraries, archives, and museums and an annotated reading list of the literature the research group consulted during our research. We believe it is riskier to do nothing and become irrelevant to our user communities than to start using social media features
Parametric design of developable structure based on yoshimura origami pattern
No full textOrigami is an ancient art form and can be divided into rigid and non-rigid origami. Rigid origami is suitable for the design of building structures because the panels are not twisted and deformed during the folding process. Currently, rigid origami structures are generally built with steel. However, compared with natural, non-polluting wood, steel has a high energy consumption and a high environmental impact. Based on this situation, this paper designs a developable wooden building structure using the Yoshimura origami model. First, the Jacobian matrix method was used to analyze the degree of freedom of the basic unit of the Yoshimura origami pattern, following which the motion trajectory required by the target structure was obtained. Secondly, by analyzing the relationship between the plane angle α and dihedral angle θ, three interaction rules were obtained, and the formula for determining the structure size was established by using the plane angle α, dihedral angle θ, the number of valley folds n and the unit length l. Subsequently, two enhancement schemes, the quadrangle enhancement scheme and the triangle enhancement scheme, were proposed to increase the height of the structure. After comparing the deformation and failure types of origami structures based on Cross-Laminated Timber, a triangular reinforcement scheme was chosen to increase the height of the structure. Finally, a new connection method was developed that allowed the origami structure to be practically applied. This research demonstrates the possibility of developing a timber structure based on Yoshimura origami
Continuous assay of protein tyrosine phosphatases based on fluorescence resonance energy transfer
No full textAn assay method that continuously measures the protein tyrosine phosphatase (PTP)-catalyzed dephosphorylation reaction based on fluorescence resonance energy transfer (FRET) was developed as an improvement of our previously reported discontinuous version [M. Nishikata, K. Suzuki, Y. Yoshimura, Y. Deyama, A. Matsumoto, Biochem. J. 343 (1999) 385-391]. The assay uses oligopeptide substrates that contain Mca [(7-methoxycoumarin-4-yl)acetyl] group as a fluorescence donor and DNP (2,4-dinitrophenyl) group as a fluorescence acceptor, in addition to a phosphotyrosine residue located between these two groups. In the assay, a PTP solution is added to a buffer solution containing a FRET substrate and chymotrypsin. The PTP-catalyzed dephosphorylation of the substrate and subsequent chymotryptic cleavage of the dephosphorylated substrate results in a disruption of FRET, thereby increasing Mca fluorescence. In this study, we used FRET substrates that are much more susceptible to chymotryptic cleavage after dephosphorylation than the substrate used in our discontinuous assay, thus enabling the continuous assay without significant PTP inactivation by chymotrypsin. The rate of fluorescence increase strictly reflected the rate of dephosphorylation at appropriate chymotrypsin concentrations. Since the continuous assay allows the measurement of initial rate of dephosphorylation reaction, kinetic parameters for the dephosphorylation reactions of a FRET substrate by Yersinia, T-cell and LAR PTPs were determined. The continuous assay was compatible with the measurement of very low PTP activity in a crude enzyme preparation and was comparable in sensitivity to assays that use radiolabeled substrates
Motion analysis of a foldable barrel vault based on regular and irregular Yoshimura Origami
No full textThis paper investigates the geometry of a foldable barrel vault with Yoshimura Origami patterns during the motion. On the base of the geometry analysis of the origami unit, the radius, span, rise, and longitudinal length of the foldable barrel vault with regular Yoshimura Origami pattern in all configurations throughout the motion are determined. The results show that the radius of curvature and the span increase during deployment. But the rise increases first, followed by a decrease with increasing fold angle. Furthermore, the influence of the apex angle of the origami unit and the numbers of triangular plates in the span direction on the geometric parameters is also investigated. Finally, the method to obtain the rise and span of the barrel vault with irregular origami pattern is also given
DS_10.1177_0022034520913250 – Supplemental material for Effects of Sulfonylureas on Periodontopathic Bacteria-Induced Inflammation
No full textSupplemental material, DS_10.1177_0022034520913250 for Effects of Sulfonylureas on Periodontopathic Bacteria-Induced Inflammation by Y. Kawahara, T. Kaneko, Y. Yoshinaga, Y. Arita, K. Nakamura, C. Koga, A. Yoshimura and R. Sakagami in Journal of Dental Research</p
Newborn care practices in rural Bangladesh
No full textBackground: Neonatal mortality is high in Bangladesh. Most of the neonatal deaths are preventable through simple and cost-effective essential newborn care interventions. Studies to document the determinants of unhealthy newborn care practices are scarce.Objective: The objective of this study is to describe the pattern of neonatal care practices andtheir determinants in rural Bangladesh.Methodology: This study is based on baseline data of a community-based intervention to assess impact of limited postnatal care services on maternal and neonatal health-seeking behavior. Data from 510 women, who had a live birth at home 1 year prior to survey, of six randomly selected unions of an Upazila (subdistrict) were analyzed.Results: Majority of the respondents were at an age group of 20–34 years. Only 6% had delivery by skilled providers. Immediate drying and wrapping, and giving colostrums to newbornswere almost universal. Unhealthy practices, like unclean cord care (42%), delayed initiation of breastfeeding (60%), use of prelacteals (36%), and early bathing (71%) were very common. Muslims were more likely to give early bath (adjusted odds ratio [OR]: 2.01; 95% confidence interval [CI]: 1.13–3.59; P=0.018) and delay in initiating breastfeeding (adjusted OR: 1.45;95% CI: 1.18–1.78; P,0.001) to newborns. Practice of giving prelacteals was associated with teenage mothers (adjusted OR: 2.26; 95% CI: 1.19–4.28; P=0.013) and women’s lack of education (adjusted OR: 2.64; 95% CI: 1.46–4.77; P=0.001).Conclusion: Unhealthy neonatal care practices are widespread in rural Bangladesh. Continued education to the community and home delivery attendants on essential newborn care could benefit newborn survival in Banglades
昆虫食・昆虫料理をめぐる心理的要因の検討に向けて
No full textOne of the authors, S.Uchiyama, who is conducting bug-eating meetings for several years, has a naive question about the psychological factors why the participants in his meetings are interested in bug-eating. In Section 1, Uchiyama points out the importance of bug-eating and of its popularization.
He explains that insects are rich in nutrition and many are even more nutritionally balanced than meat or fish. In Section 2, the first author, Yoshimura, introduces a psychological study to catch the difference of the attitudes and the senses to the bug-eating between the participants in Uchiyama’s meetings and the general public who have not yet participated in the meetings. Among the conceivable methods, a principal component analysis is used in the present research. Different from the general public, the attitudes and the senses of the participants can not be put into one major component. Yoshimura discusses that the participants in the meetings have multi-phasic attitudes and senses to the bug-eating
Evidence of carrier accumulation effects on the response enhancement in thin-film electrochromic devices
No full text
- …
