300 research outputs found
Letter from Roy N. Sato, Counsellor to Mr. George H. Hand, Chief Engineer, Rancho San Pedro, August 7, 1924
Requests a meeting (includes Mr. R. Sunada) with Hand to discuss [Stanley] Mitsugi Okano's land lease in Perry, California
Letter from [William] J. Tachibana to Mr. Geo. [George] H. Hand, Rancho San Pedro, September 30, 1925
Refers to land he is interested in leasing, which is close to the land he currently leases. Identifies individuals affiliated with the land and the area including Mr. M. Kozai, Mr. Sunada and "the Mexican boy". Includes a stamp with name and address
Follistatin-derived peptide expression in muscle decreases adipose tissue mass and prevents hepatic steatosis
Myostatin, a member of the transforming growth factor (TGF)-β superfamily, plays a potent inhibitory role in regulating skeletal muscle mass. Inhibition of myostatin by gene disruption, transgenic (Tg) expression of myostatin propeptide, or injection of propeptide or myostatin antibodies causes a widespread increase in skeletal muscle mass. Several peptides, in addition to myostatin propeptide and myostatin antibodies, can bind directly to and neutralize the activity of myostatin. These include follistatin and follistatin-related gene. Overexpression of follistatin or follistatin-related gene in mice increased the muscle mass as in myostatin knockout mice. Follistatin binds to myostatin but also binds to and inhibits other members of the TGF-β superfamily, notably activins. Therefore, follistatin regulates both myostatin and activins in vivo. We previously reported the development and characterization of several follistatin-derived peptides, including FS I-I (Nakatani M, Takehara Y, Sugino H, Matsumoto M, Hashimoto O, Hasegawa Y, Murakami T, Uezumi A, Takeda S, Noji S, Sunada Y, Tsuchida K. FASEB J 22: 477–487, 2008). FS I-I retained myostatin-inhibitory activity without affecting the bioactivity of activins. Here, we found that inhibition of myostatin increases skeletal muscle mass and decreases fat accumulation in FS I-I Tg mice. FS I-I Tg mice also showed decreased fat accumulation even on a control diet. Interestingly, the adipocytes in FS I-I Tg mice were much smaller than those of wild-type mice. Furthermore, FS I-I Tg mice were resistant to high-fat diet-induced obesity and hepatic steatosis and had lower hepatic fatty acid levels and altered fatty acid composition compared with control mice. FS I-I Tg mice have improved glucose tolerance when placed on a high-fat diet. These data indicate that inhibiting myostatin with a follistatin-derived peptide provides a novel therapeutic option to decrease adipocyte size, prevent obesity and hepatic steatosis, and improve glucose tolerance.</jats:p
AgandCuloadedonTiO2/graphite as a catalyst for �Escherichia coli- contaminated water disinfection
TiO2 film was synthesized by means of the chemical bath deposition (CBD) method from TiCl4
as a precursor and surfactant cetyl trimethyl ammonium bromide (CTAB) as a linking and assem-
bling agent of the titanium hydroxide network on a graphite substrate. Ag and Cu were loaded
on the TiO2 film by means of electrodeposition at various applied currents. Photoelectrochemical
testing on the composite of Ag–TiO2/G and Cu–TiO2/G was used to define the composite for
Escherichia coli-contaminated water disinfection. Disinfection efficiency and the rate of disinfection
of E. coli-contaminated water with Ag–TiO2/G as a catalyst was higher than that observed for
Cu–TiO2/G in all disinfection methods including photocatalysis (PC), electrocatalysis (EC), and
photoelectrocatalysis (PEC). The highest rate constant was achieved by the PEC method using
Ag–TiO2/G, k was 6.49 × 10−2
CFU mL−1
min−1
. Effective disinfection times of 24 h (EDT24)
and 48 h (EDT48) were achieved in all methods except the EC method using Cu–TiO2/G.
Keywords: Ag–TiO2/G, Cu–TiO2/G, Escherichia coli, disinfectio
Isospectral, non-isometric Riemannian manifolds
summary:The author gives a survey of the history of isospectral manifolds that are non-isometric discussing the work of Milnor, Vign\'eras, Sunada, and de Turck and Gordon. She describes the construction of continuous isospectral deformations as introduced by Gordon, Wilson, De Turck et al. She also discusses the construction of isospectral plane domains due to Gordon, Webb, and Wolpert. Some new examples of isospectral non-isometric manifolds are given
Properties and applications of the vector Harper operator / Stuart Yates.
Includes copies of articles co-authored by the author in the appendix.Bibliography: leaves 61-63.v, 131 leaves : ill. ; 30 cm.This thesis examines a vector-valued generalization of the Harper operator on a graph with a free action of a discrete group, the scalar version of which was defined by Sunada. A spectral approximation result is obtained for the vector Harper operator (and more generally for a large class of operators) which states that when the group is amenable, the spectral density function can be approximated by the average spectral density functions of finite approximations to the operator with arbitrary boundary conditions.Thesis (Ph.D.)--University of Adelaide, Dept. of Pure Mathematics, 200
Topics in empirical industrial organization
This thesis consists of three parts, covering essential topics in empirical industrial organization, including the auction designs, welfare effects of vertical agreements, and consumer responses to marketing strategies. The first chapter of the thesis examines the competitive effect of splitting the award among multiple bidders in an auction as an alternative to the traditional one-winner-take-all auction with China's national drug procurement split-award auction. Theoretically, it demonstrates that split-award auctions consistently boost participation but only decrease che expected procurement cost if no participation would have occurred in an otherwise winner-take-all auction. Empirically, the chapter's findings reveal that split-award auc- 'ions moderately increase average participation by 0.85 bidders (17%) but significantly raise the unit expected procurement cost by 4 CNY (38%). The second chapter examines the competitive effects of resale price maintenance RPM). In this vertical agreement, the retailer has to sell the products at a price range set y the manufacturer. Specifically, the chapter examines the channel through inventory decisions under demand uncertainty by focusing on the Japanese publishing industry. A model in which prices and inventory are determined before the realization of demand is estimated, and the counterfactuals show that shifting to the wholesale model will decrease the consumer surplus due to the inventory reduction and the resulting increase in prices of new titles. The third chapter examines how consumers react when their favorite product is removed using a novel dataset of vending machine purchases in Japanese train stations and a synthetic difference-in-differences approach. The results reveal that for regular consumers, favorite product removals would reduce their purchases in their favorite vending machine but have no impact on their overall purchases at the station because of within-and between-vending machine substitutions. The variety-seeking tendency is hypothesized and tested to explain such heterogeneous consumer responses.</p
Cristalografía Topológica
El objetivo de este trabajo es presentar las estructuras de los cristales como ejemplos motivadores
para una iniciación a la teoría general de los espacios recubridores. Hemos seguido para ello
el libro [5] de Toshikazu Sunada, junto con su resumen en el artículo [4], pues es la primera
exposición detallada de los fundamentos de la cristalografía topológica.
Sunada basa su estudio en el grupo fundamental (ver [2]) y después se restringe a la clase de las
aplicaciones recubridoras abelianas. Sin embargo, hemos preferido usar directamente el primer
grupo de homología de un grafo y trabajar desde el inicio con aplicaciones recubridoras abelianas
como propone John Baez en [1].
El trabajo consta de cinco capítulos que pasamos a detallar. En el primero, damos algunas
definiciones sobre grupos y acciones de grupos y presentamos el tipo de grafos con los que
trabajaremos; en el segundo, hablamos de las relaciones de homotopía y homología sobre grafos;
en el tercero, definimos los conceptos de grafos recubridores, grafos recubridores regulares y
grafos recubridores abelianos; en el cuarto, damos la definición de cristal topológico como grafo
recubridor abeliano de un grafo finito y en particular, hablamos del grafo universal abeliano
sobre un grafo base dado; finalmente en el quinto, damos una serie de ejemplos de cristales
topológicos.
Terminamos remarcando que este estudio se centra solamente en los elementos básicos de la
cristalografía topológica y no tiene en cuenta los aspectos geométricos que se presentan al considerar condiciones físico-químicas de los cristales que aparecen en la naturaleza. Esto último
tiene el fin de buscar la representación espacial más ajustada al verdadero cristal, atendiendo a
principios como el de mínima acción. Estas consideraciones forman la segunda parte de [5], que
queda fuera de este trabajo.The main purpose of this paper is to present the crystal structures as motivating examples for
introducing the general theory of covering spaces. We have followed Toshikazu Sunada’s book
[5], together with its summary in the article [4], because it is the first detailed exposition of the
foundations of Topological Crystallography.
Sunada bases his study on the fundamental group (see [2]) and then restricts to the class of
abelian covering maps. However, we opted for using directly the first homology group of a
graph and work from the beginning with abelian covering maps as John Baez suggests in [1].
The paper consists of five chapters that we describe as follows. In the first, we detail various
definitions about groups and group actions and present the type of graphs which we will work
with; in the second, we talk about homotopy and homology relations on graphs; in the third,
we define the concepts of covering graphs, regular covering graphs and abelian covering graphs;
in the fourth, we give the definition of a topological crystal as an abelian covering graph of a
finite graph and in particular, we speak of the universal abelian graph on a given base graph;
finally in the fifth, we give some examples of topological crystals.
Let us finish by pointing out that this study focuses only on the basic elements of topological
crystallography and does not take into account the geometric aspects that arise when considering
the physical and chemical properties of crystals that appear in nature. This leads to focus the
reserach on finding the spatial representation that is more adjusted to the real crystal, attending
to principles such as that of minimum action. These considerations form the second part of [5],
which is left out of this work.Universidad de Sevilla. Grado en Matemática
High-Resolution C<sup>18</sup>O Mapping Observations of Heiles' Cloud 2 – Statistical Properties of the Line Width –
Counting and Averaging Problems in Graph Theory
Paul Gunther (1966), proved the following result: Given a continuous function f on a compact surface M of constant curvature -1 and its periodic lift g to the universal covering, the hyperbolic plane, then the averages of the lift g over increasing spheres converge to the average of the function f over the surface M.
Heinz Huber (1956) considered the following problem on the hyperbolic plane H: Consider a strictly hyperbolic subgroup of automorphisms on H with compact quotient, and choose a conjugacy class in this group. Count the number of vertices inside an increasing ball, which are images of a fixed point x in H under automorphisms in the chosen conjugacy class, and describe the asymptotic behaviour of this number as the size of the ball goes to infinity.
In this thesis, we use a well-known analogy between the hyperbolic plane and the regular tree to solve the above problems, and some related ones, on a tree. We deal mainly with regular trees, however some results incorporate more general graphs
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