131,126 research outputs found

    Road of the library: the Wroblewski Library of the Lithuanian Academy of Sciences, 1912–2012

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    Straipsnyje bendrais bruožais aptariama Lietuvos mokslų akademijos Vrublevskių bibliotekos genezė ir raida daugiau kaip per 100 metų. Įstaigos istorija apžvelgiama tam tikrais laikotarpiais, stengiantis iškelti kiekvieno iš jų ypatybes, tačiau kartu iš akių nepametant bendro raidos vaizdo. 1912-1931 metai laikytini Bibliotekos kūrimo, 1931-1940 – Valstybinės Vrublevskių bibliotekos, o 1941-2009 – Lietuvos mokslų akademijos bibliotekos laikotarpiu. 2009 m. rugsėjo 29 d. Lietuvos mokslų akademijos prezidiumas sugrąžino įstaigos pavadinime turėtą Vrublevskių vardą, lapkričio 24 d. patvirtino naujus bibliotekos nuostatus. Kiek vėliau įvykus esminėms permainoms Lietuvos mokslo institucijų sistemoje, prasidėjo naujas – Lietuvos mokslų akademijos Vrublevskių bibliotekos – etapas. Reikšminiai žodžiai: Helena Drege; Juozas Marcinkevičius; Lietuvos mokslų akademijos Vrublevskių biblioteka (LMA Vrublevskių biblioteka; LMAVB; Wroblewski Library of the Lithuanian Academy of Sciences); Lituanistikos institutas; Rytų Europos tyrimų institutas; Stefanas Burhardtas; Stefanas Rygielis; Tadas Stanislovas Vrublevskis; Helena Drege; Institute of Eastern European Studies; Institute of Lithuanian Studies; Juozas Marcinkevičius; Stefan Burhardt; Stefan Rygiel; Studies; Tadeusz Stanislaw Wroblewski; The Institute of Lithuanian; The Wroblewski Library of the Lithuanian Academy of SciencesThe article overviews the genesis and development of the Wroblewski Library of the Lithuanian Academy of Sciences over more than a century. The history of the institution is discussed in terms of several periods, both attempting to identify the specifics unique to each period and keeping in mind the general trend of the Library’s development. The article names 1912–1931 as the period of the establishment of the Library, 1931–1940, as the one of the Wroblewski State Library, and 1941–2009, as that of the Library of the Lithuanian Academy of Sciences. On September 29, 2009 the Presidium of the Lithuanian Academy of Sciences returned to the Library the former name of Wroblewski, and on November 24 of the same year, it approved new regulations for the Library. Meanwhile, the system of Lithuanian scientific institutions underwent a series of important changes. These events marked the beginning of a new period, that of the Wroblewski Library of the Lithuanian Academy of Sciences

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Magnesium ions inhibit the stimulation of inositol phospholipid hydrolysis by endogenous excitatory amino acids in primary cultures of cerebellar granule cells.

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    Omission of Mg2+ from the incubation buffer results in a six- to eightfold increase in [3H]inositol-1-phosphate ([3H]Ins-1-P) accumulation in primary cultures of cerebellar granule cells at 7-9 days in vitro. This increase is reversed by low concentrations of 2-amino-5-phosphono-valerate (APV), a result indicating that the absence of Mg2+ facilitates the activation of a specific receptor by the endogenous excitatory amino acids (presumably L-glutamate and L-aspartate) released from the granule cells. The absence of Mg2+ also potentiates the action of exogenously applied N-methyl-D-aspartate (NMDA), L-glutamate, L-aspartate, and kainate. In contrast, the action of quisqualate is virtually unaffected by Mg2+ and is resistant to APV inhibition. Addition of the depolarizing agent veratridine enhances the accumulation of [3H]Ins-1-P also in Mg2+-containing buffer. The action of veratridine is antagonized by APV, a result suggesting that, under depolarized conditions, the NMDA receptor can be activated by the endogenously released excitatory amino acids, despite the presence of Mg2+. Accordingly, in the presence of Mg2+, veratridine potentiates the action of exogenously applied NMDA but does not facilitate the action of quisqualate

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.

    A. D. Fricke, author

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    Black and white photograph of author, A. D. Fricke

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Scholarly Communication and Publishing Lunch and Learn Talk #11: The ULS Open Access Author Fee Fund

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    At the May 2014 talk, you will learn about the ULS Open Access Author Fee Fund--what it is, why we do it, how it works, and how the program is going so far

    Serine-O-phosphate, an endogenous metabolite, inhibits the stimulation of inositol phospholipid hydrolysis elicited by ibotenic acid in rat hippocampal slices.

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    Serine-O-phosphate (PS) inhibits the accumulation of 3H-inositolmonophosphate elicited by ibotenic acid in rat hippocampal slices incubated in the presence of 7 mM Li+. This inhibition is concentration- dependent and stereoselective, L-PS being 5 fold more potent than D-PS. Among different structural analogues of PS, only L-serine weakly antagonizes the action of ibotenic acid, whereas phosphorylcholine, phosphorylethanolamine and phosphothreonine are inactive even at high concentrations. These results are consistent with the hypothesis that L-PS may act as an endogenous regulator of excitatory amino acid receptor function

    The R&D Tax Incentives

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    This article sets out some background information and reflections of the author on the R&D tax incentive schemes included in the Common Corporate Tax Base (CCTB) Proposal. In particular the author analyzes the stimulus to private R&D through ad hoc tax incentives included in the CCTB Proposal and dives into the actual provisions included in the Proposal highlighting the most relevant issues connected with their design and interpretation. Moreover, the author explores the interaction between the CCTB Proposal and the granting by Member States of domestic R&D tax incentives
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