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Jae Won Choi
No full text학위논문(박사)--아주대학교 일반대학원 :분자과학기술학과,2014. 8TABLE OF CONTENTSi
LIST OF FIGURES vi
LIST OF TABLES vii
ABBREVIATIONS viii
ABSTRACTxi
Chapter I 1
1. Intervertebral Disc (IVD) 2
1.1 Anatomy and development 2
1.2 Development 6
1.3 Cell population 8
1.4 Biochemical composition 11
1.5 Properties and function 17
1.6 Intervertebral disc degeneration and diseases 20
2. Tissue engineering for IVD regeneration 23
2.1 Tissue engineering 23
2.2 Cell source and strategy for IVD regeneration 24
2.2.1 Nucleus pulposus cells 25
2.2.2 Mesenchymal stem cells 26
2.3 Cell carriers for IVD regeneration 27
2.3.1 Fibrin and fibrinogen 28
2.3.2 Hyaluronic acid 29
2.4 Cell signal inducer for IVD regeneration 30
2.4.1 LIUS (low-intensity ultrasound) 30
3. Aim and title of this study 32
CHAPTER II Disc regeneration using autologous MSCs and fibrin/hyaluronic acid composite 33
1. Introduction 34
2. Materials and Methods 37
2.1 Isolation and culture of autologous mesenchymal stem cells 37
2.2 Preparation of fibrin and hyaluronic acid (Fi/HA) composite gel 37
2.3 Study design 38
2.4 Preparation of injured IVD model and materials transplantation 39
2.5 Magnetic resonance imaging 41
2.6 Macroscopic grading of IVD 42
2.7 Histological analysis 44
2.8 Statistical analysis 46
3. Result 47
3.1 Grades of disc degeneration by MRI 47
3.2 Gross evaluation 49
3.3 Histologic examination 53
4. Discussion 56
CHAPTER III Disc regeneration using Low-intensity ultrasound (LIUS) 60
1. Introduction 61
2. Materials and Methods 63
2.1 Study design 63
2.2 Preparation of injured intervertebral disc model 63
2.3 Treatment of Low-intensity ultrasound (LIUS) 66
2.4 Histological analysis 66
3. Results 67
3.1 Gross finding of intervertebral injury 67
3.2 Proteoglycan evaluation by safranin-O 69
3.3 Evaluation of collagen structure and deposition 69
4. Discussion 75
Chapter IV 78
REFERENCE 79
국문요약 88Doctora
Face Tracking Using Adaptive Particle Filter and Active Apperance Model with Incremental PCA
No full text1
The Peace Thought of Chi-won Choi
No full text신라 말기의 사상가, 시인, 정치인이었던 최치원은 유불도와 풍류도에 능통한 지식인이었다. 그의 사상을 평화관의 입장에서 생명 평화사상, 소극적 평화사상, 적극적 평화사상, 차이의 평화관으로 나누어 조명하였다. 최치원은 풍류도, 도교, 불교를 회통(會通)하는 생명 평화관을 가졌다. 그는 모든 생명과 인간이 다 같이 존엄하고 평등하며 서로 평화롭게 공존하고 그 속에서 인간과 온 생명이 하나로 범아일여(梵我一如)를 형성하다가 함께 해탈을 하기를 바랐다. 실제로 그는 함양의 태수로 부임하였을 때 위천의 홍수를 막기 위하여 둑을 쌓는 대신 숲을 조성하고 실개천을 만들어 생명을 살리면서도 홍수를 막는 대안을 택하였다. 최치원은 전쟁터에서든 이를 기억하는 장소든, 전쟁과 평화를 대조하면서 후자를 지향하였으며, 부처님의 가피를 받아 이 땅 신라가 아예 전쟁 자체가 없는 평화로운 나라가 되기를 원하였으며, 무기를 거두는 것이 평화를 가져오는 길일뿐만 아니라 모든 생명을 잘 살게 하는 길이라고 피력하였다. 최치원은 생명이 위기를 겪고 사람들의 본성이 어지러운 원인을 개인적인 요인만이 아니라 세상과 시국 때문인 것으로 파악하는 사회 구조적인 인식을 하였다. 이에 먼저 마음속에서 나쁜 마음을 씻어내는 재(齋)에 진력하고 환란이 오지 않게끔 경계하여 폭력과 다툼을 아예 없애는 계(戒)에 힘써야 한다며 전쟁과 폭력을 근본적으로 해소하려는 적극적 평화사상을 피력하였다. 최치원의 평화 사상을 21세기의 맥락에서 조명할 때, 그의 생명평화사상은 심층생태론과 상통하며, 홍수를 막기 위하여 상림을 조성한 대안은 근대성의 위기를 극복하는 탈근대적 대안으로 적용될 수 있다. 곧은 마음에서 비롯된 다름 인정의 사유는 근대적 주체가 동일성에 포획되어 타자를 상정하여 배제하고 혐오와 폭력을 행한 것을 성찰하는 차이와 타자성의 사유에도 시사하는 바가 크다.Chi-won Choi was a thinker, a poet and a politician in Silla dynasty. He was a savvy intellectual familiar with Confucianism, Buddhism, Taoim, and Pungryu-do. I analyzed his thoughts from the standpoint of the peacemaker by dividing his thoughts into four categories: life -peace ideology, passive peace ideology, active peace ideology, the peace thought of difference. He had a ideology of life and peace that combined Buddhism, Taoism and Pungryu-do. He thought that all life and man were dignified and equal. He hoped that human beings and all life would coexist in a state of oneness of the universe and self and then reach nirvana together. In fact, when he was appointed governor, he had chosen an alternative to prevent floods while saving lives by building the Sang-rim forest of instead of dams. He directed the latter in contrasting war and peace, whether on the battlefield or in a place where he remembers it. He wanted that Silla dynasty would be a peaceful country with no war itself, under the protection of the Buddha. He thought that eliminating weapons is not only a way to make peace, but a way to live all the lives well. He identified people and lives as being in crisis because of the state and the situation. He tried not only to oppose the war passively but actively to prevent it. He insisted that the war would be prevented by getting rid of fundamentally bad feelings and eliminating its causes. I illuminated his thought in the context of the 21st century. His thoughts are in line with the ideology of deep ecology. His choise that build the Sang-rim forest can be applied to post-modern alternatives. Owing to be captured by identity, modern subjects excluded and committed violent against others. So, we reflect on the violence of identity and seek alternatives of the ideas of difference and alterity. His ideas are similar to this a little
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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