5,533 research outputs found
Wit-Russisch-Nederlands Gezondheids Informatie Centrum, Gomel, Wit-Rusland. Wit-Russisch-Nederlands Humanitair Hulp Project 'Gomel project'
No full textIn het kader van het Wit-Russisch-Nederlands Humanitair Hulpproject, naar aanleiding van het ongeval met de kernreactor van Tsjernobyl in 1986 werd een Gezondheidsinformatie- centrum opgericht in Gomel. Hier werd een nieuw communicatieconcept gelanceerd. Preventieve gezondheidszorg programma's werden gestart ; het centrum vervult een kernfunctie bij de gezondheidscommunicatie voor de bevolking en voor werkers in het beroepsveld. Gedurende 1993 werden de bevolkingsvragen zorgvuldig genoteerd en geanalyseerd. De resultaten van de analyse gaven aan dat het Centrum een belangrijke functie bekleedt bij het verwijzen van patienten naar de juiste specialisten of ziekenhuizen en als laag-drempelige informatiebron dient voor degenen die een "second opinion" verlangen. Tevens functioneert het als informatiebron met betrekking tot j vragen van sociale, psycho-sociale en sociaal-economische aard. Verder dient het centrum als informatiebank voor het publiek en de beroepsgroepen voor vragen met betrekking tot straling. Het nieuwe communicatieconcept (met als belangrijke component het persoonlijk contact) is goed ontvangen door de bevolking van Gomel goed ontvangen. Het ontwikkelen van preventieve gezondheidszorg programma's voor specifieke doelgroepen werd een hoeksteen van het beleid van het Centrum. Aanbevelingen voor de toekomst besluiten dit rapport.This report describes the launching and the implementation of the Belarussian-Dutch Health Information Centre, an objective in a project aimed to alleviate the negative consequences of the Chernobyl nuclear power plant accident on April 26, 1986. In a newly established Health Information Centre in Gomel a new communication strategy was introduced in which trainings on health care programmes for professionals were performed concerning health communication with the population. During 1993 questions put to the medical consultants were extensively analysed and it was concluded that the Centre is developing a pivotal function in referring people to the relevant medical specialists or hospitals. It serves as a low-barrier source of information for patients who seek a second opinion and for questions on general health care and health education and it is developing towards a main centre for questions on social, psycho-social and socio-economic problems of the population. Furthermore, the Centre serves as a centre for information about radiation matters for the general public and professionals. Recommendations for the future management strategy conclude this report.VW
A finite element method for 1D and 2D shallow water
No full textThe finite dement method has been used to develop two numerical tools for a Boussinesq shallow water equation, 2DH and 1DH. In both models, an automatic unstructured mesh generator has been employed to assure the convergence and stability of the numerical solution through the assumption of a Courant number close to one in the whole domain. Partially reflecting- absorbing boundary conditions has been carried out to model the open seaward contour and other contour types. In the 1DH numerical model has been carried out the finite element version of the Deigaard et al break wave model and it is valid for spilling breaks. A new intuitive and numerical break rule has been developed to simulate the plunging break mode. The results obtained with both models had been compared with the equivalent results of others numerical methods and experimental data for the same problem type such as pure diffraction and step varying bottoms.27
The SSC of the Generalised Jahangir’s Graph Jm,k and its Algebraic Characterizations
No full textIn this article, we present important combinatorial and algebraicproperties of spanning simplicial complex (SSC) of the generalised Jahangir’sgraph Jm,k. We describe the relation to find f−vectors associatedto Δs(Jm,k) and determine the Hilbert series for the SR-ring KΔs(Jm,k).In the end, we present the associated primes of the facet ideal IF(Δs(Jm,k))and the Cohen-Macaulay characterization of the SR-ring of Δs(Jm,k).AMS (MOS) Subject Classification Codes: Primary 13-P10, Secondary 13-F20, 13-C14, 13-H10.Corresponding Author: Agha KashifKey Words: Simplicial Complexes, f-vectors, Spanning Trees, Face Ring, Hilbert Series, CohenMacaulay
To <i>JM</i> on Its 75th Anniversary
No full text This article discusses how Journal of Marketing ( JM) has influenced marketing science and practice by publishing articles on substantive topics relevant to customers, managers, organizations, markets, and society. The journal's 75th anniversary coincides with the 50th anniversary of the Marketing Science Institute (MSI). Frequently, JM and MSI have collaborated to address important substantive marketing issues identified in MSI's Research Priorities. The author highlights seminal articles on brand equity; business-to-business marketing (including sales force management); connecting marketing information, metrics, and strategy; consumer behavior; innovation, new product development. and product management; marketing orientation and capabilities; and market research, methodology and services. She also draws attention to articles that have won the Sheth Foundation/ JM Award and the H. Paul Root Award. The article describes how JM‘s knowledge dissemination is amplified by powerful social network effects. Ideas in JM articles diffuse through the business community, influencing the mind-set of managers worldwide. </jats:p
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
No full text\ua9 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.Studies showed that JM-20, a benzodiazepine-dihydropyridine hybrid molecule, protects against rotenone and 6-hydroxydopamine neurotoxicity. However, its protective effects against cytotoxicity induced by endogenous neurotoxins involved in Parkinson’s disease (PD) pathogenesis have never been investigated. In this study, we evaluated the ability of JM-20 to inhibit alpha-synuclein (aSyn) aggregation. We also evaluated the interactions of JM-20 with aSyn by molecular docking and molecular dynamics and assessed the protective effect of JM-20 against aminochrome cytotoxicity. We demonstrated that JM-20 induced the formation of heterogeneous amyloid fibrils, which were innocuous to primary cultures of mesencephalic cells. Moreover, JM-20 reduced the average size of aSyn positive inclusions in H4 cells transfected with SynT wild-type and synphilin-1-V5, but not in HEK cells transfected with synphilin-1-GFP. In silico studies showed the interaction between JM-20 and the aSyn-binding site. Additionally, we showed that JM-20 protects SH-SY5Y cells against aminochrome cytotoxicity. These results reinforce the potential of JM-20 as a neuroprotective compound for PD and suggest aSyn as a molecular target for JM-20
An investigation into the benefits and constraints of shifting freight traffic from roads onto high-speed railways
No full text© 2019 WIT Press. The environmental, economic and social impacts associated with the continuing increase in the global freight transport has necessitated more than ever the need for a more effective and sustainable freight transport system. High Speed Railways (HSR) may provide the solution as they have the ability to move goods quickly, safely and economically which can sufficiently improve the trade links within vast regions such as the European Union and extend that to Asian countries. The major issues concerning freight transport are greenhouse gas emissions and dependency on fossil fuel which mean that railway freight transport particularly HSR freight would be the most competitive mode. Many countries have invested in developing HSR but at present, HSR is more regularly used for passengers than for freight although there are an increasing number of countries who operate HSR freight services. Some HSR systems are not profitable as the demand for travel is not sufficient and there is a significant larger haulage capacity available, and thus they need additional funding from governments. Shifting freight from roads onto railways will improve the economic performance of HSR, reduce the amount of fuel used by the transport industry and reduce the greenhouse gas emission. This research considers the future trends and possibilities of shifting freight from roads to HSR lines and analyses the operational and technological constrains concerning freight traffic and the corresponding capabilities of HSR. Most of the data and information used in the research are gathered from relevant online sources including in depth research of the HSR in selected countries, available railway statistics and European and Institutional publications. The expected outcome of this research may contribute to developing more suitable means to improve the economic, environmental and social sustainability of HSR particularly for freight transport
Uterine transplantation: a promising surrogate to surrogacy?
No full textUterine transplantation: a promising surrogate to surrogacy?
Grynberg M1, Ayoubi JM, Bulletti C, Frydman R, Fanchin R.
Author information
Abstract
Infertility due to the inability of the uterus to carry a pregnancy ranks among the most unresolved issues in reproductive medicine. It affects millions of women worldwide who have congenital or acquired uterine affections, often requiring hysterectomy, and potentially represents a considerable fraction of the general infertile population. Patients suffering from severe uterine infertility are currently compelled to go through gestational surrogacy or adoption; both approaches, unfortunately, deprive them of the maternal experience of pregnancy and birth. Uterine transplantation represents an outstanding, yet complex, perspective to alleviating definitive uterine infertility. In the past decades, a number of scientific experiments conducted both in animals and women, focusing on uterine transplantation, have led to promising results. Collectively, these findings undoubtedly constitute a sound basis to clinically apply uterine transplantation in the near future. This paper is, however, an overview not only of the extent and limitations of accumulated scientific knowledge on uterine transplantation, but also its ethical implications, in an effort to define the actual place of such an approach among the therapeutic arsenal for alleviating infertility.
© 2011 New York Academy of Sciences
Translation and interpretation: Translation redundancy reconsidered
No full textInterpretation is an integral part of the process of translating. This article raises the question of whether interpretation fo a literary work by a translator should be guided by extratextual factors or not. The discussion is illustrated with examples taken from David Hawkes' translation of a Chinese classic, A Dream of Red Mansions. As the work of a scholar-translator, Hawkes' version is richly supplemented with disclosures concerning the characters and explanations of the cultural environment embodied in the novel. In many cases, however, this translation procedure is redundant and explanatory, enlightening the readers but at the same time robbing them of the pleasure of literary interpretation and cultural exploration. By means of this illustration of translation redundancy, the author points out that there is difference between a scholar who helps the interpretation fo a work and a translator who presents a work close to its original version. It is particularly important to pay attention tot his difference in literary translations in a cross-cultural situation involving two enormously different cultures.Language & LinguisticsA&HCI0ARTICLE1,SI115-12
INTERNATIONAL FINANCIAL REPORTING STANDARDS (IFRS), BAIK BAGI USAHA MIKRO KECIL MENENGAH? (Studi Kasus: UMKM JM KERIPIK)
No full textABSTRAKUndang-undang nomor 20 tahun 2008 tentang Usaha Makro Kecil Menengah (UMKM), usaha kecil adalah usaha ekonomi produktif yang berdiri sendiri, yang dilakukan oleh orang perseorangan atau badan usaha yang bukan merupakan anak perusahaan atau bukan cabang perusahaan yang memiliki, dikuasai atau menjadi bagian baik langsung maupun tidak langsung dari usaha menengah atau usaha besar yang memenuhi kriteria. JM Keripik merupakan salah salah UMKM yang bergelut dibidang produksi dan penjualan. IFRS merupakan seperangkat standard yang dikeluarkan oleh Dewan Standard Akuntansi Internasional (IASB). IFRS berguna untuk menyusun laporan keuangan yang dapat diterima di dunia Global.Penulistertarik untukmengetahuipencatatankeuanganJM Keripik dan apakah perlu merekomendasikan IFRS pada UMKM JM Keripik. Metode penelitian yang digunakaan penulis adalah kualitatif yaitu observasi dan wawancara. Dari hasil penelitian banyak terdapat pencatatan-pencatatan yang kurang terperinci, UMKM JM Keripik hanya memilki empat macam pencatatan yaitu pencatatan mengenai: 1.Stock barang, 2.Supliyer, 3.Costumer dan 4.Stock toko, pencatatan ini hanya dapat dimengerti oleh pemilik JM Keripik. Sebaiknya pemilik UMKM JM Keripik mengganti laporan keuangan yang sederhana ke laporan keuangan yang semestinya dan yang berbasis IFRS karena IFRS membawa dampak positif bagi UMKM dan merupakan standar akuntansi keuangan yang digunakan dunia global. Kata Kunci : UMKM, IFRS, JM Keripik ABSTRACT Act number 20 of 2008 concerning the Macro Small and Medium Enterprises, small businesses are productive economic activities that stand alone, carried out by an individual or business entity that is not a subsidiary or not a branch of the company that owns, controlled or become part either directly or indirectly from medium or large businesses that meet the criteria. JM Keripik which deals in the field of production and sales. IFRS is a set of standards issued by the International Accounting Standards Board (IASB). IFRS is useful for preparing financial statements that is acceptable in the global world. Authors interested in knowing the financial records of JM Keripik and whether to recommend IFRS on JM Keripik. The research method is qualitative author of observation and interviews. From the research there are many registries are less detailed, JM Keripik has only four kinds of recording is recording about: 1.Stock goods, 2.Supliyer, 3.Costumer and 4.Stock shop, registration can only be understood by the owner of JM Keripik. JM Keripik owners should replace the simple financial reports to the appropriate financial statements and IFRS-based IFRS for Macro Small and Medium Enterprises had a positive impact and a financial accounting standards global world. Keywords : UMKM, IFRS, JM Keripi
Gridlock: chaos and confusion in our prisons
No full textBehind the headlines and political posturing, the prison system is in crisis, with inhumane conditions and overcrowding making a mockery of justice, argues Peter JM Wayne, who has spent over 20 years inside. Copyright (c) 2008 The Author. Journal compilation (c) 2008 ippr.
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