12,219 research outputs found
The Women's international study of long-duration oestrogen after menopause (WISDOM): a randomised controlled trial
No full textBackground: At the time of feasibility work and final design of the trial there was no randomised control trial evidence for the long-term risks and benefits of hormone replacement therapy. Observational studies had suggested that long term use of estrogen was likely to be associated, amongst other things, with reduced risks of osteoporosis and ischaemic heart disease and increased risks of breast and endometrial cancer. Concomitant use of progestogens had been shown to protect against endometrial cancer, but there were few data showing how progestogen might affect estrogen actions on other conditions. Disease specific risks from observational studies suggested that, overall, long-term HRT was likely to be beneficial. Several studies showed that mortality from all causes was lower in HRT users than in non-users. Some secondary cardiovascular prevention trials were ongoing but evidence was also required for a range of outcomes in healthy women. The WISDOM trial was designed to compare combined estrogen and progestogen versus placebo, and estrogen alone versus combined estrogen and progestogen. During the development of WISDOM the Women's Health Initiative trial was designed, funded and started in the US. Design: Randomised, placebo, controlled, trial. Methods: The trial was set in general practices in the UK (384), Australia (94), and New Zealand (24). In these practices 284175 women aged 50–69 years were registered with 226282 potentially eligible. We sought to randomise 22300 postmenopausal women aged 50 – 69 and treat for ten years. The interventions were: conjugated equine estrogens, 0.625 mg orally daily; conjugated equine estrogens plus medroxyprogesterone acetate 2.5/5.0 mg orally daily; matched placebo. Primary outcome measures were: major cardiovascular disease, osteoporotic fractures, breast cancer and dementia. Secondary outcomes were: other cancers, all cause death, venous thromboembolism and cerebro-vascular disease. Results: The trial was prematurely closed during recruitment following publication of early results from the Women's Health Initiative. At the time of closure, 56583 had been screened, 8980 entered run-in, and 5694 (26% of target of 22,300) randomised. Those women randomised had received a mean of one year of therapy, mean age was 62.8 years and total follow-up time was 6491 person years. Discussion: The WISDOM experience leads to some simple messages. The larger a trial is the more simple it needs to be to ensure cost effective and timely delivery. When a trial is very costly and beyond the resources of one country, funders and investigators should make every effort to develop international collaboration with joint funding
Letter From William Bell Scott to Mr Chambers
No full textabstract: Concerning Scott's thanks, his writings about his own works, and a manuscript of "The Nightingale Unheard."Seller's Description: Reads "A.L.S. from Author to Mr. Chambers explaining how busy he is... The sonnet is printed in the book. Fredeman: 56.7 £87.50"Handwritten Note: Unknown handwriting at top right reads "June 1st 1877."Publication Details: "The Nightingale Unheard" published in "Poems" by William Bell Scott.Creation Date Details: Undated range is the author's lifespan.Provenance: Removed from:
Poems / by William Bell Scott. Ballads, studies from nature, sonnets, etc. / illustrated by seventeen etchings by the author and L. Alma Tadema. Publisher London : Longmans, Green, 1875. CALL #
HAYDEN SPECIAL COLL SPEC PRB-13
Wisdom and apocalyptic in the Gospel of Matthew : a comparative study with 1 Enoch and 4QInstruction
No full textRecent scholarship has demonstrated that Matthew's gospel has significantly developed
both sapiential and apocalyptic elements within its narrative. Little attention has been paid,
however, to the question of how these two features of Matthew's gospel might relate to one
another. It is this gap in scholarly literature that the present study is intended to fill, by means of a
comparative study with two other texts of mixed genre: 1 Enoch and 4Qlnstruction.
An examination of these texts demonstrates that each is marked by an inaugurated
eschatology, within which the revealing of wisdom to an elect group, defined in distinction to the
Jewish parent group, serves as the pivotal moment of inauguration. In addition, within
4Qlnstruction the idea is developed that possession of this revealed wisdom allows the remnant
to live in fidelity to the will of the Creator and to the patterns built-in to the original creation.
Thus, possession of revealed wisdom facilitates a recovery of creation.
These findings provide lines of enquiry that may be brought to Matthew. Three sections
of the gospel are examined (chapters 5-7; 11-12; 24-25). It is argued that Jesus is presented as an
eschatological figure who reveals wisdom to an elect group. This wisdom cannot be reduced to
great moral insight or interpretation of Torah, but is presented as prophetic revelation, happening
in eschatological time. It remains the case, however, that Matthew presents it as wisdom and
presents Jesus as a sage.
More tentatively, it is suggested that creation provides the patterns for the ethical
requirements of Jesus' wisdom, thus indicating that the idea of restored creation is also at work in
Matthew. The fall of the temple may also be connected in Matthew's narrative to such a
restoration, but again, the evidence for this is not clear
The soteriology of James in light of earlier Jewish Wisdom literature and the Gospel of Matthew
No full textThe epistle of James has been neglected in NT studies, caught between its
relationship with Paul and the claim that it has no theology. Even as it experiences a
resurgence of study, surprisingly no full-length survey exists on James as the epistle of
“faith and works.” Approaches to James have neglected its soteriology and, in
consequence, its theological themes have been separated or studied only in connection
with Paul. As “moral character,” however, “faith” and “works” fit within a coherent
theology of God’s mercy and judgment.
This study provides a sustained reading of James as a Jewish-Christian document.
Because James presents the “faith” and “works” discussion in context of “can such faith
save?” (2:14), the issue becomes one of soteriology and final judgment. Both the “law of
freedom” and the “word of truth” demand faithful obedience—the “works.” Moreover,
God’s character and deeds in election form the basis for human “works” of mercy and
humble obedience, while future judgment is in accordance with virtuous character.
It has been established that James shares methodology and concerns with prior
wisdom literature. This thesis therefore examines key ideas developing across the Jewish
literature and Jesus’ teaching as presented by Matthew, and highlights developing views of
God saving and judging his people. Within the first two chapters, James gives a high view
of God’s work in calling and redeeming, providing wisdom to his people, and instilling the
long-anticipated new covenant that they might live in obedience, humility and purity in
accordance with his character and will. Because of God’s saving work, he justly judges
those who fail to live mercifully, while his mercy triumphs for those who obey. God
begins the work and sustains those who ask; but only those who submit to the “perfect
law of freedom,” whose faith works, receive mercy when God enacts his final justice
Scott Belsky in Conversation with DesignByThem - Part One.mp4
No full textWatch here as Scott Belsky (CEO/Founder Behance + Author Making Ideas Happen) joins Sydney design duo Sarah Gibson and Nicholas Karlovasitis from DesignByThem to discuss some of the challenges facing creative companies as they try to grow their business. In part one Nick and Sarah get some great advice from Scott about what makes an effective partnership and how to learn from the challenges that can arise. Scott also explains the Behance technique of ?Concepting Teams? with representatives from all areas of the business to brainstorm issues or new ideas
Cardozo AELJ Author Interview Series: Scott Semaya, Class of 2023
No full textThe Cardozo AELJ Author Interview Series seeks to give our readers further insight into the Articles and Notes published in the Cardozo Arts & Entertainment Law Journal. In this interview, Scott Semaya discusses his Note, Name, Image and Likeness: Giving College Athletes the Clearest Guidance to Best Profit off Their NIL, which was published in Volume 41, Issue 2.
This post was originally published on the Cardozo Arts & Entertainment Law Journal website on June 6, 2023. The original post can be accessed via the Archived Link button above
Cardozo AELJ Author Interview Series: Scott Semaya, Class of 2023
No full textThe Cardozo AELJ Author Interview Series seeks to give our readers further insight into the Articles and Notes published in the Cardozo Arts & Entertainment Law Journal. In this interview, Scott Semaya discusses his Note, Name, Image and Likeness: Giving College Athletes the Clearest Guidance to Best Profit off Their NIL, which was published in Volume 41, Issue 2.
This post was originally published on the Cardozo Arts & Entertainment Law Journal website on June 6, 2023. The original post can be accessed via the Archived Link button above
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Cardozo AELJ Author Interview Series: Scott Semaya, Class of 2023
No full textThe Cardozo AELJ Author Interview Series seeks to give our readers further insight into the Articles and Notes published in the Cardozo Arts & Entertainment Law Journal. In this interview, Scott Semaya discusses his Note, Name, Image and Likeness: Giving College Athletes the Clearest Guidance to Best Profit off Their NIL, which was published in Volume 41, Issue 2.
This post was originally published on the Cardozo Arts & Entertainment Law Journal website on June 6, 2023. The original post can be accessed via the Archived Link button above
Scott Belsky in Conversation with DesignByThem - Part Two.mp4
No full textSarah Gibson and Nicholas Karlovasitis from DesignByThem continue their conversation with Scott Belsky (CEO/Founder Behance + Author Making Ideas Happen). They discuss the relationship between taking financial risks in creative enterprise whilst valuing professional standards in their work
Article entitled "Emmett J. Scott, Author and Business Man, Dies"
No full textNewspaper article entitled "Emmett J. Scott, Author and Business Man, Dies." Mr. Scott died on Dec. 12, 1957
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