11 research outputs found
Psychosocial consequences of living kidney donation. From screening to intervention
No full textContains fulltext :
187342.pdf (Publisher’s version ) (Open Access)Radboud University, 18 april 2018Promotores : Evers, A.W.M., Hilbrands, L.B., Hoitsma, A.J. Co-promotor : Middendorp, H. va
Stiffness and Layout Tailoring of a Morphing High-lift System with Aeroelastic Loads
No full textAerospace Materials & ManufacturingAerospace Engineerin
Spatially explicit farming system modelling for an efficient agri-environmental policy design
No full textA mathematical programming model is developed and associated to a spatial pattern index (Ripley L function) to analyse the optimal reserve design and implementation for the Little Bustard conservation in Plaine de Niort. The model structure corresponds to three spatial levels, fields, farm and landscape. Simple in terms of area representation, it is detailed in terms of farm behaviour and spatially explicit. The model is applied in a normative and in a positive way. The major findings of the normative approach relate to the trade-offs between the reserve pattern and its cost. It was found that the environmentally optimal reserve, which is randomly dispersed across the zone, is the most costly one. Within the positive approach, it is illustrated that the various reserve patterns generated within the normative approach can be obtained through relatively simple uniform contract structures. The most effective contract structure is a degressive set of two payments enabling the farms to enroll at least a small share of their land.Biodiversity, spatial optimization, mathematical programming, Environmental Economics and Policy, Farm Management,
Growth through innovation: eight practical steps for entrepreneurs
No full textInnovation and entrepreneurship are considered to be renewal, revitalisation and growth engines. However, their impact is highly uncertain, unpredictable and frustrating managers, who are pushed outside their comfort zones. Growth through Innovation explores how organisations typically confront reality and explains why they struggle with several dangerous myths. This book illustrates how you can do it differently by leveraging distinctive capabilities and by using an innovation lead compass. Basically, you will discover how to successfully reach your destination and influence your destiny. The author aspires to fill a critical gap in the existing literature by providing clear insights, simple diagnostic tools and techniques, unique strategies and practical steps
Optimization of a variable-stiffness skin for morphing high-lift devices
No full textOne of the possibilities for the next generation of smart high-lift devices is to use a seamless morphing structure. A passive composite variable-stiffness skin as a solution to the dilemma of designing the structure to have high enough stiffness to withstand aerodynamic loading and low stiffness to enable morphing is proposed. The variable-stiffness skin is achieved by allowing for a spatial fibre angle and skin thickness variation on a morphing high-lift system. The stiffness distribution is tailored to influence the deformation of the structure beneficially. To design a realistic stiffness distribution, it is important to take aerodynamic and actuation loads into account during the optimization. A two-dimensional aero-servo-elastic framework is created for this purpose. Skin optimization is performed using a gradient-based optimizer, where sensitivity information is found through application of the adjoint method. The implementation of the aero-servo-elastic environment is addressed and initial optimization results presented. The results indicate that a variable-stiffness skin increases the design space. Moreover, the importance of taking the change in aerodynamic loads due to morphing skin deformation into account during optimization is demonstrated.Department of Aerospace StructuresAerospace Engineerin
Aeroelastic tailoring using lamination parameters: Drag reduction of a Formula One rear wing
No full textThe aim of the present work is to passively reduce the induced drag of the rear wing of a Formula One car at high velocity through aeroelastic tailoring. The angle-of-attack of the rear wing is fixed and is determined by the required downforce needed to get around a turn. As a result, at higher velocity, the amount of downforce and related induced drag increases. The maximum speed on a straight part is thus reduced due to the increase in induced drag. A fibre reinforced composite torsion box with extension-shear coupled upper and lower skins is used leading to bending-torsion coupling. Three-dimensional static aeroelastic analysis is performed loosely coupling the Finite Element code Nastran and the Computational Fluid Dynamics panel code VSAERO using ModelCenter. A wing representative of Formula One rear wings is optimised for minimum induced drag using a response surface methodology. Results indicate that a substantial induced drag reduction is achievable while maintaining the desired downforce during low speed turns.Aerospace Structures & Design MethodologyAerospace Engineerin
Combining transplant professional’s psychosocial donor evaluation and donor self-report measures to optimise the prediction of HRQoL after kidney donation: an observational prospective multicentre study
No full textHealth and self-regulatio
Pre-donation cognitions of potential living organ donors: The development of the Donation Cognition Instrument in potential kidney donors
No full textE-HEalth treatment in Long-term Dialysis (E-HELD): study protocol for a multicenter randomized controlled trial evaluating personalized Internet-based cognitive-behavioral therapy in dialysis patients
No full textBACKGROUND: Kidney failure and dialysis treatment have a large impact on a patient’s life. Patients experience numerous, complex symptoms and usually have multiple comorbid conditions. Despite the multitude of problems, patients often have priorities for improvement of specific aspects of their functioning, which would be helpful for clinicians to become informed of. This highlights a clear need for patient-centered care in this particular patient group, with routine screening as a vital element to timely recognize symptoms and tailored treatment to match individual patients’ needs and priorities. By also providing feedback on patient’s screening results to the patient itself, the patient is empowered to actively take control in one’s mostly uncontrollable disease process. The current paper describes the study design of a multicenter randomized controlled trial evaluating the effectiveness of the “E-HEealth treatment in Long-term Dialysis” (E-HELD) intervention. This therapist-guided Internet-based cognitive-behavioral therapy (ICBT) intervention is focused on and personalized to the myriad of problems that dialysis patients experience and prioritize. METHODS: After a screening procedure on adjustment problems, 130 eligible dialysis patients will be randomized to care as usual or the E-HELD intervention. Patients will complete questionnaires on distress (primary outcome measure), several domains of functioning (e.g., physical, psychological, social), potential predictors and mediators of treatment success, and the cost-effectiveness of the intervention, at baseline, 6-month follow-up, and 12-month follow-up. In addition, to take account of the personalized character of the intervention, the Personalized Priority and Progress Questionnaire (PPPQ) will be administered which is a personalized instrument to identify, prioritize, and monitor individual problems over time. DISCUSSION: The present study design will provide insight in the effectiveness of tailored ICBT in patients with kidney failure who are treated with dialysis. When proven effective, the screening procedure and the subsequent ICBT intervention could be implemented in routine care to detect, support, and treat patients struggling with adjustment problems. TRIAL REGISTRATION: NL63422.058.17 [Registry ID: METC-LDD] NL7160 [Netherlands Trial Register; registered on 16 July 2018
