1,721,453 research outputs found
sj-docx-1-msj-10.1177_13524585221122210 – Supplemental material for Leptomeningeal enhancement under different MS immunotherapies: A monocentric retrospective cohort study of 214 patients
No full textSupplemental material, sj-docx-1-msj-10.1177_13524585221122210 for Leptomeningeal enhancement under different MS immunotherapies: A monocentric retrospective cohort study of 214 patients by Friedli Christoph, Wagner Franca, Hammer Helly Noemi, Kamber Nicole, Wiest Roland, Diem Lara, Chan Andrew, Salmen Anke and Hoepner Robert in Multiple Sclerosis Journal</p
[Imaging for disorders in neurology and neurosurgery]
No full textImaging has become increasingly important for diagnosis and treatment of disorders in neurology and neurosurgery. Often, however, physicians are uncertain which imaging modality to chose for diagnosis and which techniques can be used to help for treatment. To answer a specific question clinicians have to rely on history and clinical findings. According to a cardinal clinical symptom or sign the imaging technique with the highest sensitivity and specificity for the given problem is chosen. In this review imaging techniques for the most common cardinal symptoms and signs in neurology and neurosurgery which need imaging for management are discussed
Recent developments in imaging of epilepsy.
Full text linkPURPOSE OF REVIEW
Imaging constitutes one of the key pillars in the diagnostic workup after a first seizure as well as for the presurgical workup in epilepsy. The role of imaging in emergency situations, mainly to support the adequate diagnosis, as well as its role in planning of noninvasive image-guided therapies is less well established. Here, we provide an overview on peri-ictal imaging findings to support differential diagnosis in emergency situations and describe recent attempts toward minimal invasive therapy in the treatment of epilepsy and its comorbidities based on a combination of imaging techniques with ultrasound.
RECENT FINDINGS
Peri-ictal perfusion changes can differentiate ictal stroke mimics from acute ischemic stroke if focal areas of increased perfusion are depicted by computed tomography or MRI. Postictal perfusion patterns in patients with persisting neurological symptoms are frequently normal and do not reach enough diagnostic sensitivity to differentiate between stroke and its mimics. Noninvasive magnetic resonance-techniques as arterial spin labeling may provide a higher sensitivity, especially in combination with diffusion-weighted and susceptibility-weighted MRI. Imaging guided focused ultrasound (FUS) bears the potential to ablate epileptogenic tissue and allows suppression of epileptic activity. Imaging guided blood-brain-barrier opening with FUS offers new options for local drug administration.
SUMMARY
MRI should be considered the method of choice in the differential diagnosis of peri-ictal imaging findings and their differential diagnosis. A combination of various MRI techniques with FUS opens new avenues for treatment of epilepsy.This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
Degeneration of the Ipsilateral Substantia Nigra and Red Nucleus as Well as Contralateral Dentate Nucleus after Middle Cerebral Artery Infarction.
No full textBrain Imaging After a First Seizure
Full text linkNeuroimaging is one of the main pillars of diagnostic workup in epilepsy. After a first seizure neuroimaging is indicated in all patients but those presenting
with a typical genetic generalized epilepsy. Emergency imaging is warranted if the seizures may be the symptom of an acute brain pathology. If the patient returns “back to baseline” at the time of clinical examination, MR imaging may be performed electively using a dedicated epilepsy protocol. Data on seizure recurrence rates over 10 years are still lacking for many classical brain pathologies associated with epilepsy. Novel imaging techniques may be helpful in detecting prolonged seizures and mimics in the emergency setting
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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