1,720,973 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
HUBUNGAN KADAR ANTI MULLERIAN HORMONE (AMH) DENGAN KEBERHASILAN STIMULASI OVARIUM PADA FERTILISASI IN VITRO METODE PROTOKOL PANJANG
HUBUNGAN KADAR ANTI MULLERIAN HORMONE (AMH)DENGAN KEBERHASILAN STIMULASI OVARIUM PADAFERTILISASI IN VITRO METODE PROTOKOL PANJANGRidho Permana, Shofwal Widad, M. LutfiABSTRACTBackground: Patient with decline oocyte number and quality assumed has lower Anti Mullerian hormone(AMH). AMH concentration which expressed by the granulosa cells of preantral and small antral folliclesindirectly determine the ovarian reserve. Therefore, AMH may be used as a marker of ovarian ageing andassociated with ovarian response in in vitro fertilization (IVF).Objective: To determine the effect of Anti Mullerian Hormone (AMH) on ovarian response in IVF longprotocol method.Method: This research is a retrospective cohort study in Permata Hati Fertility Clinic, IVF program-Dr.Sardjito Hospital, Yogyakarta, Indonesia. Seventy one cycle enrolled in an IVF program conducted fromJanuary 2011 through December 2013 at the Permata Hati Fertility Clinic.Result and Discussion: ROC curve were used to determine cut-off AMH. With cut-off point 2.59 ng/ml,subject divided into two groups (high AMH level: ≥2.59 ng/ml and low AMH level: <2.59 ng/ml). Totaldose gonadotropin was significantly different in two groups (p=0.02). High AMH and low AMH levelwere significantly associated with ovarian response (RR 2,05; CI 95% 1,32 – 2,20 ; p< 0,01). BesideAMH, multivariate analysis shows basal LH level (p=0,04; OR 7,22; CI 95% 1,09 – 47,87) and peritonealendometriosis (p=0,03; OR 7,80; IK 95% 1,15–52,81) were significantly influenced ovarian response in IVF.Conclusion: high AMH level influence ovarian response in IVF. Total dose gonadotropin on low AMH levelswas greater than high AMH level. In addition to AMH, ovarian response were influenced by basal LH leveland peritoneal endometriosis.Keywords: Anti Mullerian hormone (AMH), ovarian response, long protocol stimulation, in vitro fertilization(IVF).ABSTRAKLatar belakang: Pasien dengan penurunan jumlah dan kualitas oosit diduga mempunyai kadar AntiMullerian Hormone (AMH) lebih rendah. Konsentrasi Anti Mullerian Hormone (AMH) yang dihasilkanfolikel ovarium secara tidak langsung menggambarkan cadangan ovarium yang tersisa. Karenanya kadarAnti Mullerian Hormone (AMH) dapat digunakan sebagai prediktor yang akurat dari cadangan ovarium danrespons stimulasi ovarium pada fertilisasi in vitro.Tujuan: Untuk mengetahui pengaruh kadar Anti Mullerian Hormone (AMH) terhadap keberhasilanstimulasi ovarium pada fertilisasi in vitro pada metode protokol panjang.Metode: Penelitian ini menggunakan rancangan kohort retrospektif observasional.Hasil dan Pembahasan: Sebanyak 71 siklus dari 71 pasangan yang menjalani fertilisasi in vitro disertakandalam penelitian sesuai dengan kriteria inklusi dan eksklusi. Dengan cut off point AMH ditetapkan 2,59 ng/ml, maka subyek ini dibagi menjadi 2 kelompok yaitu ≥2,59 ng/ml sebagai kelompok AMH tinggi dan <2,59 ng/ml sebagai kelompok AMH rendah. Perbedaan bermakna antara dua kelompok ditemukan pada dosistotal gonadotropin (p=0,02).Terdapat perbedaan bermakna respons stimulasi ovarium antara AMH tinggidan AMH rendah (RR 2,05; IK 95% 1,32 – 2,20 ; p< 0,01). Kadar LH basal (p=0,04; OR 7,22; IK 95% 1,09 –47,87) dan endometriosis peritoneal (p=0,03; OR 7,80; IK 95% 1,15–52,81) juga mempengaruhi respons terhadap stimulasi ovarium.Kesimpulan : AMH tinggi mempengaruhi respons terhadap stimulasi ovarium. Dosis total gonadotropinpada AMH rendah dibutuhkan lebih banyak dibandingkan dengan AMH tinggi. Selain AMH, responsterhadap stimulasi ovarium juga dipengaruhi oleh kadar LH basal, dan endometriosis peritoneal.Kata kunci : kadar Anti Mullerian hormone (AMH), stimulasi ovarium protokol panjang, fertilisasi in vitro.Bagian Obstetri Ginekologi, Fakultas Kedokteran, Universitas Gadjah Mada Yogyakart
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
PERBANDINGAN FRAGMENTASI DNA FOLIKEL PRIMER JARINGAN KORTEKS OVARIUM FRESH NON TRANSPLAN, FRESH TRANSPLAN, VITRIFIKASI NON TRANSPLAN DAN VITRIFIKASI TRANSPLAN PADA MODEL BINATANG
Latar Belakang: Kriopreservasi jaringan ovarium merupakan salah satu pendekatan cara mempertahankan fertilitas pada wanita yang diprediksi mengalami kegagalan ovarium prematur sebagai konsekuensi dari kemoterapi, radioterapi atau kelainan genetik. Kriopreservasi dengan vitrifikasi menjadi fokus investigasi meskipun masih terdapat kontroversi terhadap hasil akhirnya, karena belum ada protokol optimal untuk vitrifikasi serta data vitrifikasi jaringan ovarium manusia masih terbatas dan berlainan hasil
Tujuan: Mengevaluasi metode vitrifikasi modifikasi Suzuki pada folikel primer jaringan korteks ovarium Metode: Metode penelitian ini menggunakan uji eksperimental jenis one shot case study dengan menggunakan 28 jaringan korteks ovarium kambing (Capra aegagrus hircus) yang terbagi dalam 4 perlakuan yaitu jaringan korteks ovarium fresh non transplan, jaringan fresh ditransplantasikan ke CAM (chorioallantoic membrane) ayam, jaringan di vitrifikasi non transplan dan jaringan di vitrifikasi yang ditransplantasikan ke CAM. Penilaian fragmentasi DNA folikel primer pada setiap grup dilakukan dengan metode TUNEL (TdT-mediated dUTP-biotin nick end labeling) yang dilakukan di laboratorium fisiologi Fakultas Kedokteran, Kesehatan Masyarakat dan Keperawatan Universitas Gadjah Mada Yogyakarta. Analisis statistik data penelitian dilakukan dengan uji ANOVA.Hasil: Fragmentasi DNA pada folikel primer grup fresh non transplan : 17,39 %, fresh transplan : 12,5 %, vitrifikasi non transplan : 17,39 % dan vitrifikasi transplan 7,4 %. Uji komparasi 4 grup didapatkan p = 0.782 (p<0.05).Kesimpulan: Tidak terdapat perbedaan signifikan fragmentasi DNA folikel primer jaringan korteks ovarium antara fresh non transplan, fresh transplan, vitrifikasi non transplan dan vitrifikasi transplan yang menunjukkan metode vitrifikasi modifikasi Suzuki dapat mempertahankan folikel dari fragmentasi DNA
PENGARUH STATUS RAWATAN BAYI DI NICU TERHADAP RISIKO DEPRESI PASCASALIN
PENGARUH STATUS RAWATAN BAYI DI NICU TERHADAP RISIKO DEPRESI PASCASALINYasmina Ema1, Rukmono Siswishanto2, Shofwal Widad3ABSTRACT Background: Postnatal depression is a frequent complication after childbirth, approximately occurred 6.5 to 14.5% in postnatal women. Untreated postnatal depression can have adverse long-term effects. Episodes of depression can be chronic so it will affect the quality of life. Depression that occurs in the mother will affect behavioral, emotional, cognitive, and child interpersonal is in the future. Post partum women whose babies are takenb care in the NICU is believed to have the level of depression, level of anxiety, and trauma symptoms that were higher compared with the women who don’t. The occurrence of depression is associated with a variety of factors, including the adaptation with a sick baby, having a baby that isolated in the NICU, and the stress arising from the NICU environment itself.Objective: To observe the influence of the status of infants in the NICU treatment on the incidence of postnatal depression.Method: This study used a cross-sectional design. The subjects were post portum women days 14-21 who met the criteria. Subjects were divided into 2 groups, one group of mothers with babies in the NICU and one group of mothers with babies under wentrooming. This study used edinburgh post natal depression scale (EPDS). Statistical test used was chi-square and logistic in regression.Results and Discussion: The subjects who met the criteria were 144 women. A total of 19 women was suffered from postnatal depression (13.1%). Educational status of husband and infant admision to NICU giving significant differences on postnatal depression (p = 0.027 and p = 0.047). Infant care in the NICU increased postnatal depression 3.34 times compared rooming in group (CI 95% 1.12 to 9.99).Conclusion: The proportion of postnatal depression group of mothers with infants treated in the NICU were larger than the rooming in group. Keyword: postnatal depression, neonatal intensive care admission, EPDS ABSTRAK Latar Belakang: Depresi pascasalin merupakan salah satu komplikasi yang sering muncul setelah persalinan, terjadi pada 6,5-14,5% dari wanita pascasalin. Depresi pascasalin yang tidak diobati dapat memiliki efek jangka panjang yang merugikan. Episode depresi ini bisa menjadi kronis sehingga akan mempengaruhi kualitas hidupnya. Depresi yang terjadi pada ibu akan mempengaruhi perilaku, emosi, kognitif, dan interpersonal anak di kemudian hari. Wanita pascasalin yang bayinya dirawat di NICU dipercaya mempunyai tingkat depresi, tingkat kecemasan, dan gejala trauma yang lebih tinggi dibandingkan dengan wanita pascasalin yang bayinya menjalani rawat gabung. Terjadinya depresi ini berhubungan dengan berbagai macam faktor, meliputi adaptasi dengan bayi yang sakit, memiliki bayi yang terisolasi di ruangan NICU, dan stress yang timbul karena lingkungan NICU itu sendiri.Tujuan: Mengetahui pengaruh status rawatan bayi di NICU terhadap kejadian depresi pascasalin.Metode: Penelitian ini menggunakan rancangan potong lintang. Subyek penelitian adalah pasien pascasalin hari ke 14-21 yang memenuhi kriteria inklusi. Subyek dibagi menjadi 2, kelompok ibu dengan bayi yang dirawat di NICU dan kelompok ibu dengan bayi rawat gabung. Penelitian ini menggunakan Edinburgh Post Natal Depression Scale (EPDS).Hasil dan Pembahasan: Subyek penelitian yang memenuhi kriteria berjumlah 144 orang. Sebanyak 19 ibu menderita depresi pascasalin (13,1%). Pendidikan suami dan status rawat bayi memberikan perbedaan secara bermakna terhadap depresi pascasalin (p= 0,027 dan p=0,047). Perawatan bayi di NICU meningkatkan risiko depresi pascasalin sebesar 3,34 kali dibanding perawatan bayi secara rawat gabung (CI 95% 1,12-9,99). Kesimpulan: Proporsi depresi pascasalin kelompok ibu dengan bayi dirawat di NICU lebih besar dibanding kelompok ibu dengan bayi rawat gabung.Kata kunci: depresi pascasalin, status rawat bayi NICU, skor EPDS. 1,2,3 Bagian Obstetri dan Ginekologi Fakultas Kedokteran Universitas Gadjah Mad
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Evaluation of the Key Performance Indicators of the In Vitro Fertilization (IVF) Program at the Permata Hati Clinic, Dr. Sardjito in 2019-2020
Background: One of the efforts that can be done to overcome infertility is In Vitro Fertilization (IVF) or the IVF process is a process in which the egg is fertilized by sperm outside the body. Where in the In Vitro Fertilization effort, hormone stimulation is carried out, in principle, is an effort to add a number of hormones from the outside (exogenous hormone) which functions as control of the reproductive process, so that the reproductive cycle can be accelerated or can be carried out outside its natural environment. Given the many risks that arise, a measurement is needed to determine the success rate of the IVF program itself. Research Performance indicator or key performance indicator (KPI) is a type of performance measurement of any process, whether in biomedical or non-biomedical fields, may be subject to inherent deviations from the optimum limit or from the set limit.Objective: Conduct an evaluation with Key Performance Indicators on In Vitro Fertilization (IVF) patients at the Permata Hati Clinic, Dr. Sardjito.Method: This research is a descriptive observation because the researcher only observes without treating the object to be studied. This research was conducted at Dr. RSUP. Sardjito because RSUP Dr. Sardjito owns the Permata Hati infertility clinic, which provides patients with IVF (in vitro fertilization or IVF) procedures. Data collection was carried out especially in the medical record section which was carried out in January 2019 - January 2020.Results and Discussion: The variables of ICSI damage level, normal ICSI fertilization rate, normal IVF success rate, IVF fertilization failure rate, blastocyst cryosurvival rate, and implantation level (cleavage stage) have not been able to meet the key performance indicators. , and the implantation rate (blastocyst stage) met the key performance indicatorsConclusion: Permata Hati Clinic Performance RSUP Dr. Sardjito is still under competency and aspirational performance based on key performance indicators. Keywords: Key Performace Indicator; In Vitro Fertilization; Assisted reproductive technique
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