396 research outputs found
Letter From Leigh Hunt to Edward Moxon
No full textabstract: Concerning Hunt's agitation at Mrs. Guest's actions and appeals to Moxon and Hunt's request that Moxon show this note to Mr. Forster.Curator's Note: This letter was partially published in A Sentimental Library, Comprising Books Formerly Owned by Famous Writers, Presentation Copies, Manuscripts and Drawings written by Harry Bache Smith (1860-1936), a successful American lyricist, writer, and composer.Provenance: Most likely donated to Special Collections along with the following three books:
1) Stories from the Italian poets : with lives of the writers / by Leigh Hunt. Publisher London : Chapman and Hall, 1846.
Local Call Number: SPEC E-1906 v.1
2) Stories from the Italian poets : with lives of the writers / by Leigh Hunt. Publisher London : Chapman and Hall, 1846.
Local Call Number: SPEC E-1906 v.2
3) A sentimental library, comprising books formerly owned by famous writers, presentation copies, manuscripts, and drawings collected and described by Harry B. Smith. With fifty-six illustrations. Publisher [New York] Privately Printed [by the De Vinne press] 1914.
Local Call Number: SPEC BA-152Postage Details: Address: Mr Moxon, Bond Street. Marked "Private." Folded for mailing
Retraining displaced workers : what can developing countries learn from OECD nations?
No full textThe governments of most industrial countries provide financial support for adult training programs intended to retrain displaced workers. The author draws lessons from the experience of six industrial countries (Australia, Britain, Canada, Japan, Sweden, and the United States) on how to design and implement such retraining programs in low-income developing nations and middle-income countries. By retraining, the author means both improving job skills and remediating deficiencies in basic education. These are the lessons he emphasizes: Training programs should be independent of the educational system, with its rigid ties to degree requirements and academic schedules; links to employers must be developed and maintained so that trainees have marketable skills on completing the program. Training programs should be designed to minimize trainees'foregone earnings; basic education should be relevant to the jobs the trainees might seek. External providers of education must be made accountable - but with care; the system of accountability should also ensure that the needs of displaced workers most likely to suffer long-term unemployment are met. Not all displaced workers require relatively expansive retraining; some may need only inexpensive job-search assistance services. A permanent, institutionalized training system is preferable to short-term intervention.Labor Standards,Tertiary Education,ICT Policy and Strategies,Health Monitoring&Evaluation,Teaching and Learning
The man unmasked: or, The world undeceived, [electronic resource] : in the author of a late pamphlet, intitled, "Extracts from the proceedings of the High Court of Vice-Admiralty in Charlestown, South-Carolina," &c. With suitable remarks on that masterly performance. By Egerton Leigh. [Seven lines of quotation].
No full textHenry Laurens, in the anonymously published Extracts of the proceedings .. (Philadelphia, 1768 and Charleston, 1769), charged Leigh with misconduct in his position as judge of the Court of Vice-Admiralty.Errata note, p. [17], 3rd count.Signatures: [A]p4s B-2Dp4s (D4 verso blank; H1 missigned G)Evans,Electronic reproduction.English Short Title Catalog,Reproduction of original from Library of Congress
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Driven to Despair: Confronting Racial Inequity in North Carolina\u27s License Suspension Practices
No full textHundreds of thousands of North Carolina drivers have a suspended license for unpaid traffic court fines and fees. The practice of suspending drivers’ licenses for unpaid fines and fees is inequitable and counterproductive. This practice disenfranchises rural drivers and those facing poverty and creates a significant obstacle to employment. Furthermore, African-American drivers are four times as likely as non-Hispanic, white drivers to have a suspended license for unpaid fines and fees. Drawing upon lessons learned from the Driver’s License Restoration Project, the Authors conclude that legislative action is needed to remedy this inequitable and inefficient system of collecting state revenue. North Carolina should cease the practice of suspending licenses for unpaid fines and fees, pursue a decrease in criminal court fees and fines overall, and implement a sliding scale structure for fees and fines that makes a fact-specific determination about an individual’s real wages and ability to pay. This recommendation would lead to greater racial and economic equity, strengthen the North Carolina economy, and increase the aggregate amount of fees and fines collected by the state. This Article is a continuation of a prior published work, The Poverty Penalty: Driver’s License Restoration In North Carolina
Driven to Despair: Confronting Racial Inequity in North Carolina\u27s License Suspension Practices
No full textHundreds of thousands of North Carolina drivers have a suspended license for unpaid traffic court fines and fees. The practice of suspending drivers’ licenses for unpaid fines and fees is inequitable and counterproductive. This practice disenfranchises rural drivers and those facing poverty and creates a significant obstacle to employment. Furthermore, African-American drivers are four times as likely as non-Hispanic, white drivers to have a suspended license for unpaid fines and fees. Drawing upon lessons learned from the Driver’s License Restoration Project, the Authors conclude that legislative action is needed to remedy this inequitable and inefficient system of collecting state revenue. North Carolina should cease the practice of suspending licenses for unpaid fines and fees, pursue a decrease in criminal court fees and fines overall, and implement a sliding scale structure for fees and fines that makes a fact-specific determination about an individual’s real wages and ability to pay. This recommendation would lead to greater racial and economic equity, strengthen the North Carolina economy, and increase the aggregate amount of fees and fines collected by the state. This Article is a continuation of a prior published work, The Poverty Penalty: Driver’s License Restoration In North Carolina
Isolation and characterization of new mutants of the cytochrome d terminal oxidase of Escherichia coli
No full textThe cytochrome d terminal oxidase from Escherichia coli is a two-subunit, three-heme integral membrane cytochrome. Subunit I contains the heme center b\sb{558} and Subunit II, is necessary for the binding of the b\sb{595} and d heme prosthetic groups. Earlier work suggests that the N-terminus of Subunit I participates in the binding of the b\sb{595} and d heme centers. Mutants in the cytochrome d terminal oxidase from Escherichia coli were isolated using hydroxylamine mutagenesis. These mutants, isolated both in the chromosome and on plasmids, were characterized using reduced minus air-oxidized difference spectroscopy, Western immunoblotting, CO difference spectroscopy, and oxidase activity assays. Plasmic-encoded mutations were mapped by marker rescue and identified by DNA sequencing. Two new classes of cytochrome d terminal oxidase mutants were identified. Under aerobic growth conditions, one class produces both subunits, and binds both the b\sb{558} and b\sb{595} heme centers, but varying amounts of the heme d center. The mutations conferring this phenotype are in the N-terminus of Subunit II. The conclusion is that the N-terminus of Subunit II along with the N-terminus of Subunit I forms the interface between these two subunits where the b\sb{595} and d heme centers bind. The second class of mutations also produces both subunits but binds only b\sb{558} and b\sb{595}. No heme d is bound under aerobic conditions. One of these mutations was identified and is also found in the N-terminus of Subunit I confirming its involvement in the formation of the heme-binding interface. There is another phenotype associated with the above mutants. When cells containing these mutations are grown anaerobically, the stability of the mutant enzymes improved as evidenced by increased heme binding and subunit stability. During the course of this work, a technique was developed to create chromosomal replacements in E. coli. Plasmid DNA carrying the desired allele for gene replacement was transformed into a recBC sbcBC mutant of E. coli. A double cross-over event exchanges the wild-type and plasmid-encoded alleles to effect a replacement. This double cross-over event is screened for by the use of a positive drug marker linked to the replacement allele.Made available in DSpace on 2011-05-07T13:39:43Z (GMT). No. of bitstreams: 2
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Locational Marginal Pricing: When and Why Not?
No full textThis study establishes that Locational Marginal Pricing (LMP) is conceptually problematic for grid-supported centrally-managed wholesale power markets transitioning to decarbonized grid operations with increasingly diverse participants, hence with increasingly uncertain and volatile net loads. LMP assigns a common per-unit price LMP(b,T) (/MWh) without regard for the true benefits and costs of flexible dynamic power delivery. Another option, illustrated in this study, is to explore alternative conceptually-coherent product definitions, settlement rules, and bid/offer contract formulations that permit electric power grids to function efficiently as flexibility-support
insurance mechanisms enabling just-in-time power deliveries to meet just-in-time customer power demands and grid reliability requirements.JEL Classification: C6, D4, D6, L1, Q4. Length 13 pages. Original Release Date: June 30, 2023. Revision: October 11, 2023
Implantation of a single-lead atrioventricular synchronous (VDD) pacemaker in a dog with naturally occurring 3rd-degree atrioventricular block
No full textLR: 20061115; PUBM: Print; JID: 8708660; ppublishSource type: Electronic(1
Comparison of the effects of xylazine bolus versus medetomidine constant rate infusion on cardiopulmonary function and depth of anesthesia in horses anesthetized with isoflurane
No full textObjective—To compare the effects of xylazine bolus versus medetomidine constant rate infusion (MCRI) on cardiopulmonary function and depth of anesthesia in dorsally recumbent, spontaneously breathing, isoflurane-anesthetized horses.
Design—Prospective, randomized crossover study.
Animals—10 healthy adult Standardbreds.
Procedures—Horses were premedicated with xylazine or medetomidine IV. Anesthesia was induced with diazepam and ketamine and maintained with isoflurane for 150 minutes. For the xylazine treatment, end-tidal isoflurane concentration was maintained at 1.7%, and xylazine (0.2 mg/kg [0.09 mg/lb], IV) was administered as a bolus at the end of anesthesia. For the MCRI treatment, end-tidal isoflurane concentration was maintained at 1.4%, and medetomidine (0.005 mg/kg/h [0.0023 mg/lb/h], IV) was infused throughout anesthesia. Physiologic data (ie, heart rate, respiratory rate, rectal temperature, bispectral index, and electromyographic values) were compared between treatments with xylazine bolus versus MCRI.
Results—Heart rate was lower, but mean arterial blood pressure was higher from 20 to 40 minutes with MCRI treatment, compared with conventional treatment with xylazine. Respiratory rate and rectal temperature were greater with MCRI treatment. Bispectral index was lower with MCRI treatment from 80 to 150 minutes, and electromyographic values were lower with MCRI treatment from 30 to 150 minutes.
Conclusions and Clinical Relevance—In isoflurane-anesthetized horses, premedication with medetomidine followed by administration of medetomidine as a constant rate infusion resulted in decreased heart rate, higher arterial blood pressure from 20 through 40 minutes after induction of anesthesia, and better preserved body temperature, compared with conventional treatment with xylazine. Greater depth of anesthesia and muscle relaxation were seen with MCRI treatment, despite the lower isoflurane concentration.Catherine M. Creighton, Kip A. Lemke, Leigh A. Lamont, Barbara S. Horney, Christopher B. Rile
Cardiopulmonary evaluation of the use of medetomidine hydrochloride in cats
No full textOBJECTIVE: To evaluate the cardiovascular effects of the alpha2-adrenergic receptor agonist medetomidine hydrochloride in clinically normal cats. ANIMALS: 7 clinically normal cats. PROCEDURE: Cats were anesthetized with isoflurane, and thermodilution catheters were placed for measurement of central venous, pulmonary, and pulmonary capillary wedge pressures and for determination of cardiac output. The dorsal pedal artery was catheterized for measurement of arterial blood pressures and blood gas tensions. Baseline variables were recorded, and medetomidine (20 microg/kg of body weight, IM) was administered. Hemodynamic measurements were repeated 15 and 30 minutes after medetomidine administration. RESULTS: Heart rate, cardiac index, stroke index, rate-pressure product, and right and left ventricular stroke work index significantly decreased from baseline after medetomidine administration, whereas systemic vascular resistance and central venous pressure increased. However, systolic, mean, and diastolic arterial pressures as well as arterial pH, and oxygen and carbon dioxide tensions were not significantly different from baseline values. CONCLUSIONS AND CLINICAL RELEVANCE: When administered alone to clinically normal cats, medetomidine (20 microg/kg, IM) induced a significant decrease in cardiac output, stroke volume, and heart rate. Arterial blood pressures did not increase, which may reflect a predominant central alpha2-adrenergic effect over peripheral vascular effects.LR: 20061115; PUBM: Print; JID: 0375011; 0 (Adrenergic alpha-Agonists); 0 (Anesthetics, Inhalation); 26675-46-7 (Isoflurane); 86347-14-0 (Medetomidine); ppublishSource type: Electronic(1
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