126 research outputs found

    DUNIA MAGIS DALAM CERPEN LEAK PEMOROAN KARYA I WAYAN SADHA

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    of the occult not only lived in the past but penetrated freely until Era 4.0. Although the development of the world has advanced in such a way as with the sophistication of its technology, the belief in supernatural and magical things cannot be erased. The magical world has its own charms and problems in the lives of Balinese people. Undeniably, the attractiveness often invites the attention of the author in welcoming and recording the phenomenon into literary works. In this paper examines modern Balinese literary works in the form of short stories. The short stories studied were taken from a collection of Leak Pemoroan stories written by I Wayan Sadha. This study examines three short stories in a collection of Pemoroan Leak short stories entitled Jeg Pragat Ka Balian, Pemoroan Leak and Walik Sumpah. The focus of the discussion in this paper is to raise the magical aspects contained in the three short stories that have been mentioned. The magical aspects to be discussed are the Pangiwa aspect and the Panengen aspect contained in the short story.Keywords: Magic, Pangiwa, Panengen, Short Story, modern Balinese literatur

    Status gizi lansia berdasarkan pengetahuan dan aktivitas fisik, di wilayah kerja Puskesmas Sukawati 1, Gianyar, Bali

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    Peningkatan Umur Harapan Hidup dan  jumlah populasi lansia dapat mengakibatkan terjadinya transisi epidemiologi dalam bidang kesehatan akibat meningkatnya jumlah angka kesakitan karena penyakit degeneratif. Berbagai penelitian yang telah dilakukan memperlihatkan hasil bahwa masih banyak angka kejadian malnutrisi pada lansia. Namun, hingga saat ini belum ada dilakukan pendataan mengenai status gizi pada lansia di Puskesmas Sukawati I. Peneliti ingin mengkaji status gizi lansia yang ada di wilayah kerja Puskesmas Sukawati I untuk mengetahui keadaan gizi lansia di wilayah tersebut. Penelitian ini menggunakan pendekatan deskriptif kuantitatif dengan desain cross-sectional. Total sampel yang didapatkan berjumlah 72 orang dan dalam pelaksanaannya pada semua sampel telah dilakukan wawancara serta pengukuran antropometri. Dilihat dari perhitungan RLPP, 77,8%  mengalami obesitas sentral, dengan rata-rata RLPP pada sampel yang diteliti sebesar 0,95 untuk laki-laki  yang tergolong resiko obesitas rendah dan 0,92 untuk perempuan yang tergolong resiko obesitas tinggi. Berdasarkan tingkat pengetahuan tentang gizi, persebaran sampel yang memiliki pengetahuan yang kurang terbanyak pada status gizi lebih sebesar 71,4%, begitu pula dengan kelompok yang memiliki tingkat pengetahuan baik juga menunjukkan proporsi terbanyak pada status gizi lebih yaitu 86,7%. Jika dilihat dari aktivitas fisik, persebaran sampel yang memiliki aktivitas ringan terbanyak pada status gizi berlebih (92,7%). Puskesmas disarankan untuk melakukan pengukuran antropometri dan pencatatan status kesehatan lansia secara komprehensif pada Kartu Menuju Sehat untuk lansia serta konseling dengan pakar gizi mengenai kesehatan lansia untuk mengatasi masalah tersebut

    HUBUNGAN SELENIUM DAN ZINC DALAM PENCEGAHAN PENUAAN : TINJAUAN LITERATUR DAN APLIKASI DALAM ANTI-AGING MEDICINE

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    Penuaan biologis merupakan proses kompleks yang ditandai oleh akumulasi kerusakan oksidatif, pemendekan telomer, dan immunosenescence. Selenium (Se) dan zinc (Zn) adalah mikronutrien esensial yang berperan fundamental dalam memodulasi mekanisme pertahanan seluler tersebut. Tinjauan literatur ini bertujuan untuk mengevaluasi peran molekuler selenium dan zinc dalam pencegahan penuaan serta aplikasi klinisnya dalam anti-aging medicine. Penelitian ini disusun menggunakan metode narrative review dengan menganalisis 40 artikel terpilih dari database PubMed, ScienceDirect, dan Google Scholar dengan rentang publikasi tahun 2015–2025. Penelusuran literatur menggunakan pendekatan PICO yang berfokus pada mekanisme epigenetik, stabilitas genom, dan uji klinis pada populasi dewasa dan lansia. Analisis menunjukkan bahwa selenium dan zinc secara langsung memodulasi biological aging clock. Defisiensi selenium (<90 µg/L) berkorelasi signifikan dengan percepatan penuaan epigenetik yang diukur dengan DunedinPACE, meskipun manfaatnya terhadap pemanjangan telomer bersifat age-dependent (signifikan pada lansia ≥65 tahun). Pada zinc, ditemukan hubungan dosis non-linear (kurva berbentuk U); asupan adekuat terbukti menjaga stabilitas genom dan menurunkan kerusakan DNA, namun dosis berlebih (>40 mg/hari) justru mempercepat penuaan biologis. Efektivitas suplementasi juga sangat dipengaruhi oleh faktor nutrigenomik, termasuk variasi genotipe IL-6 dan p53. Selenium dan zinc bekerja secara sinergis menghambat penuaan dini melalui proteksi mitokondria, perbaikan DNA, dan regulasi inflamasi. Aplikasi klinis dalam anti-aging medicine harus mengutamakan strategi personalisasi dosis untuk mengoreksi defisiensi dan menghindari toksisitas. Pemantauan status nutrisi dan skrining genetik direkomendasikan untuk mencapai hasil preventif yang optimal

    Modeling of animal groups based on individual goals

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    Title: Modeling of animal groups based on individual goals Author: Ema Wayan Danielová Department: Department of Macromolecular Physics Supervisor: doc. RNDr. Viktor Holubec, Ph.D. Abstract: Collective motion represents a fascinating example of self-organization in non-equilibrium systems. This work introduces and examines a modified Vicsek model of collective motion, enhanced with alignment-induced local attractive and repulsive interactions. Numerical simulations demonstrate that such a system spontaneously forms stable clusters with a characteristic size determined by the interaction radius. The results show that group cohesion can be achieved even without periodic boundary conditions and by using using finite-range interactions that are reasonable from a biological perspective. Keywords: collective motion, Vicsek model, active matter, numerical simulations, self-organization, cohesion, interaction radius, non-equilibrium systemsNázev práce: Modelování skupin zvířat na základě cílů jednotlivců Autor: Ema Wayan Danielová Katedra: Katedra makromolekulární fyziky Vedoucí bakalářské práce: doc. RNDr. Viktor Holubec, Ph.D. Abstrakt: Kolektivní pohyb představuje fascinující příklad samoorganizace v nerovnovážných systémech. V této práci je navržena a zkoumána modifikace Vicsekova modelu kolektivního pohybu doplněná o lokální přitažlivé a odpudivé interakce vyvolané optimalizací směru. Numerické simulace ukazují, že takový systém spontánně vytváří stabilní skupiny s charakteristickou velikostí určenou interakčním poloměrem. Získané výsledky demonstrují, že koheze skupiny může být dosažena i bez použití periodických okrajových podmínek a s z biologického hlediska rozmumnými konečně-dosahovými interakcemi. Klíčová slova: kolektivní pohyb, Vicsekův model, aktivní hmota, numerické simualce, samoorganizace, koheze, interakční poloměr, nerovnovážné systémyDepartment of Macromolecular PhysicsKatedra makromolekulární fyzikyFaculty of Mathematics and PhysicsMatematicko-fyzikální fakult

    The Effect of the Ketogenic Diet on Weight Loss and Metabolic Risk Factors: A Systematic Review and Meta-Analysis

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    Obesity remains a major global health problem with increasing prevalence, leading to a rise in the use of dietary interventions such as the ketogenic diet. Despite its popularity, evidence regarding its effectiveness in improving metabolic parameters remains inconsistent. This study aimed to evaluate the impact of the ketogenic diet on weight loss and metabolic risk factors through a systematic review and meta-analysis. Following the PRISMA 2020 guidelines, relevant studies were retrieved from PubMed, ScienceDirect, Cochrane Library, and ProQuest databases. Eligible randomized controlled trials assessing the effects of the ketogenic diet on glucose control, blood pressure, body mass index (BMI), and lipid profiles in obese patients were included. Data extraction and quality assessment were conducted using the Risk of Bias (RoB) tool, and statistical analyses were performed with Review Manager v5.3. Nine eligible studies (n = 437 participants) were included. The ketogenic diet significantly reduced blood glucose levels (SMD = -0.27 mg/dL, 95% CI: -0.50 to -0.04, P = 0.02) and triglycerides (SMD = -28.38 mg/dL, 95% CI: -32.07 to -24.69, P < 0.001), while increasing LDL cholesterol (SMD = 17.27 mg/dL, 95% CI: 1.10 to 33.44, P = 0.04). However, no significant changes were observed in BMI, HDL, total cholesterol, or blood pressure. Funnel plot and Egger’s test results indicated no publication bias. In conclusion, the ketogenic diet demonstrates beneficial effects on glucose regulation and triglyceride reduction but has limited efficacy for weight loss and may elevate LDL levels, warranting cautious clinical application in obesity management

    Digitised comparative word list of Malay, Nias, Toba-Batak, and Enggano in Modigliani’s “L’isola Delle Donne” from 1894

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    The first release (v1.0.0) for the digitised, computer-readable Enggano word list in Modigliani (1894), with comparison from Nias, Toba-Batak, and Malay. The Enggano word list is included in the EnoLEX database. The data-source directory contains the original data in .xlsx file that the author hand-digitised from the original source (Modigliani 1894). The light annotation included reflects the content of the original source, covering several aspects. First, annotating the string component that is printed in italics in the original source; the marking is indicated by the XML tag so it can be traced computationally. Second, there is also annotation concerning remark () for a given language column in the original source, and that concerning aspect of meaning (). These annotations are still available in the WORD column of the data-output with long-table format (the column WORD2 excludes these annotations, which are transferred into the REMARK column of the long-table format). In the wide-table format of the data-output, the language columns named with ..._1 do not contain these annotations, which have been transferred into other columns named with ..._rm and ..._sem labels. The REMARK column in the two sets of data-output contains another annotation I put while transcribing from the source: the cell beginning with M-- is a comment for the Malay column while that starting with I-- is for the Italian (the reference language). The author also provided the segmented/tokenised forms. Information concerning the orthography standardisation is available on the README page of the ortho directory

    Retro-digitised Enggano-German dictionary derived from Kähler’s (1987) “Enggano-Deutsches Wörterbuch”

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    This is a hand-digitised Enggano-German Dictionary derived from Hans Kähler's (1987) “Enggano-Deutsches Wörterbuch”. We crowdsourced the digitisation process by transcribing the dictionary's content into an online database system; the system was set up by Cokorda Pramartha and I B. G. Sarasvananda in collaboration with the first author. The database is exported into a .csv file to be further processed computationally using R and manually, such as fixing typos and incorrect mapping of the entry element, providing the English and Indonesian translations, and standardising the orthography. The minor update in the current version includes adding a description of the column names for the tabular data of the digitised dictionary. The dictionary is stored as a table for three file types: .rds (for the R data format), .csv, and .tsv

    <p>Studi eksplorasi ketidakhadiran siswa rujukan Usaha Kesehatan Gigi Sekolah ke Puskesmas II Denpasar Utara<p></p> Exploratory study of the absence of School Dental Health Initiatives (UKGS) referral students to North Denpasar II Community Health Centre (Puskesmas)<p>

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    Pendahuluan: Hasil laporan UKGS Tahun 2019 di Puskesmas II Denpasar Utara sebanyak 10% dari total 660 siswa SD dirujuk untuk mendapatkan perawatan. Namun siswa SD yang memerlukan perawatan gigi tidak datang ke Puskesmas. Penelitian ini bertujuan untuk mengetahui alasan ketidakhadiran siswa SD rujukan UKGS ke Puskesmas II Denpasar Utara berdasarkan persepsi Ibu dan guru. Metode: Penelitian kualitatif menggunakan pendekatan studi eksplorasi pada SD di wilayah kerja Puskesmas II Denpasar Utara. Sebanyak 7 informan dipilih dengan metode purposive sampling terdiri dari ibu siswa rujukan UKGS, guru penanggung jawab serta petugas Puskesmas pemegang program UKGS. Data dikumpulkan dengan wawancara mendalam dan dianalisis menggunakan metode tematik. Hasil: Persepsi ibu terhadap kegiatan UKGS dirasa sangat bermanfaat dalam mencegah kerusakan gigi anak. Kesehatan gigi dan mulut belum menjadi prioritas sehingga ibu tidak rutin melakukan kontrol periodik. Ibu lebih memilih datang ke praktek swasta dengan menggunakan asuransi karena di Puskesmas cenderung menunggu lama. Persepsi guru menganggap kegiatan UKGS memberikan manfaat walau dalam pelaksanaan rujukan UKGS tidak ada formulir khusus, petugas kesehatan hanya melakukan pencatatan yang berisi identitas siswa serta keterangan gigi berlubang atau persistensi. Simpulan: Penyakit gigi dan mulut belum menjadi prioritas orang tua dibandingkan penyakit lain. Orang tua lebih memilih datang ke praktek swasta dengan menggunakan asuransi karena di Puskesmas cenderung menunggu lama dan akses sulit. Guru menganggap kegiatan UKGS memberikan manfaat walau dalam pelaksanaannya tidak ada formulir khusus mengenai hasil rujukan UKGS. Hasil rujukan diberitahu secara langsung maupun melalui media komunikasi online kepada orang tua. Kata kunci: karies gigi; rujukan UKGS; ketidakhadiran siswa; Puskesmas ABSTRACT Introduction: The results of the 2019 School Dental Health Initiatives (UKGS) report at the North Denpasar II Community Health Centre (Puskesmas) were 10% of the total 660 elementary school students referred for treatment. However, elementary school students who need dental treatment do not follow the instruction. This study aimed to determine the reasons for the absence of UKGS referral elementary school students to Puskesmas II Denpasar Utara based on the perceptions of mothers and teachers. Methods: Qualitative research using an exploratory study approach in elementary schools in the working area of North Denpasar II Community Health Centre. A total of 7 informants were selected by purposive sampling method consisting of mothers of School Dental Health Initiatives referral students, teachers in charge and Community Health Centre officers holding School Dental Health Initiatives programs. Data were collected by in-depth interviews and analyzed using thematic methods. Result: Mother’s perception of School Dental Health Initiatives activities is considered helpful in preventing tooth decay in children. Oral health has not become a priority so that mothers do not routinely do periodic check-ups. Mothers prefer to come to private practice using insurance because of a long queuing period in the Community Health Centre. The teacher’s perception is that School Dental Health Initiatives activities provide benefits even though there is no particular form in the implementation of School Dental Health Initiatives referrals; health workers only make records by writing down student identities and information about cavities or persistence. Conclusions: Dental and oral diseases have not become a priority for parents compared to other diseases. Parents prefer to come to private practice using insurance because of a long queuing period in the Community Health Centre and difficult accessibility. Teachers consider School Dental Health Initiatives activities beneficial even though there is no special form regarding UKGS referral results in practice. Referral results are notified directly or through online media to parents. Keywords: dental caries; School Dental Health Initiatives; referral; student absence; Community Health Centr

    ASTAXANTHIN MENGHAMBAT PERLEMAKAN HATI DAN PENINGKATAN KADAR SERUM GAMMA-GLUTAMYLTRANSFERASE PADA TIKUS WISTAR JANTAN YANG DIBERI MINYAK JELANTAH

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    ABSTRACT Non-alcoholic fatty liver can be triggered by used cooking oil consumption due to the formation of free radicals and the accumulation of fatty acids in the body. Astaxanthin is a powerful antioxidant that may be able to inhibit the pathogenesis of fatty liver. This study aims to determine the effect of astaxanthin in inhibiting fatty liver (steatosis) and levels of Gamma-Glutamyltransferase (GGT) in male Wistar rats given used cooking oil. An experimental study with Post-test Only Control Group Design was conducted on 36 male Wistar rats aged 3.5-4 months with an approximate bodyweight of 200-210 grams divided randomly into 2 groups. The control group was given 0.42 ml of used cooking oil + 0.5 ml of distilled water, and the treatment group was given 0.42 ml of used cooking oil + 0.2 mg of astaxanthin each day for 14 days. On day 15, blood tests and hepatic histopathology were performed to check &nbsp;GGT serum levels and steatosis. The comparative test was conducted to compare the results of the control and treatment groups. The results showed that the mean steatosis and GGT levels in the treatment group were significantly lower than the control group. It can be concluded that giving astaxanthin can inhibit fatty liver (steatosis) and increase GGT serum levels in male Wistar rats given used cooking oil. &nbsp; Keywords: Astaxanthin, Fatty liver, Gamma-glutamyltransferase, Used cooking oi
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