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Influence of diluent alkyl substitution on the extraction of Am(III) and Eu(III) by a 6,6’-bis(1,2,4-triazin-3-yl)-2,2’-bipyridine ligand dissolved in alkylated cyclohexanone Diluents
No full textSeveral alkylated cyclohexanones were investigated as potential diluents for the selective extraction of Am(III) from Eu(III) from nitric acid solutions by the CyMe4-BTBP ligand. No significant extraction of either of the metal ions was observed for these diluents themselves. In the extractions from 1 M HNO3, 3-methylcyclohexanone and 4-methylcyclohexanone gave comparable results to cyclohexanone whereas in the extractions from 4 M HNO3, 2-methylcyclohexanone, 3-methylcyclohexanone and 4-methylcyclohexanone all gave superior results. For the monomethylated diluents, DAm and SFAm/Eu decreased in the order of alkyl substitution 2 > 4 ~ 3. However, alkyl substitution of cyclohexanone significantly slows down the extraction kinetics compared to cyclohexanone, and the position of alkyl substitution was found to play an important role in the solvents properties. 3-Methylcyclohexanone was identified as the most promising of the diluent
The Association of Human Apolipoprotein C-III Sialylation Proteoforms with Plasma Triglycerides
No full textabstract: Introduction
Apolipoprotein C-III (apoC-III) regulates triglyceride (TG) metabolism. In plasma, apoC-III exists in non-sialylated (apoC-III[subscript 0a] without glycosylation and apoC-III[subscript 0b] with glycosylation), monosialylated (apoC-III[subscript 1]) or disialylated (apoC-III[subscript 2]) proteoforms. Our aim was to clarify the relationship between apoC-III sialylation proteoforms with fasting plasma TG concentrations.
Methods
In 204 non-diabetic adolescent participants, the relative abundance of apoC-III plasma proteoforms was measured using mass spectrometric immunoassay.
Results
Compared with the healthy weight subgroup (n = 16), the ratios of apoC-III[subscript 0a], apoC-III[subscript 0b], and apoC-III[subscript 1] to apoC-III[subscript 2] were significantly greater in overweight (n = 33) and obese participants (n = 155). These ratios were positively correlated with BMI z-scores and negatively correlated with measures of insulin sensitivity (S[subscript i]). The relationship of apoC-III[subscript 1] / apoC-III[subscript 2] with S[subscript i] persisted after adjusting for BMI (p = 0.02). Fasting TG was correlated with the ratio of apoC-III[subscript 0a] / apoC-III[subscript 2] (r = 0.47, p<0.001), apoC-III[subscript 0b] / apoC-III[subscript 2] (r = 0.41, p<0.001), apoC-III[subscript 1] / apoC-III[subscript 2] (r = 0.43, p<0.001). By examining apoC-III concentrations, the association of apoC-III proteoforms with TG was driven by apoC-III[subscript 0a] (r = 0.57, p<0.001), apoC-III[subscript 0b] (r = 0.56. p<0.001) and apoC-III[subscript 1] (r = 0.67, p<0.001), but not apoC-III[subscript 2] (r = 0.006, p = 0.9) concentrations, indicating that apoC-III relationship with plasma TG differed in apoC-III[subscript 2] compared with the other proteoforms.
Conclusion
We conclude that apoC-III[subscript 0a], apoC-III[subscript 0b], and apoC-III[subscript 1], but not apoC-III[subscript 2] appear to be under metabolic control and associate with fasting plasma TG. Measurement of apoC-III proteoforms can offer insights into the biology of TG metabolism in obesity.The article is published at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.014413
author = {M. Friendly}, title = {A Brief History of Data Visualization},
No full textyear = {2006}, publisher = {Springer-Verlag}, address = {Heidelberg}, booktitle = {Handbook of Computational Statistics: Data Visualization}, volume = {III}, editor = {C. Chen and W. H\&quot;ardle and A Unwin}, pages = {???--???}, note = {(In press)}, © copyright by the author(s
A naval travesty : the dismissal of Admiral Sir John Jellicoe, 1917
No full textThis dissertation relates to the dismissal of Admiral Jellicoe, First Sea Lord from November 1916 to December 1917, by Sir Eric Geddes, First Lord of the Admiralty, at the behest of the Prime Minister, David Lloyd George. The dismissal was peremptory and effected without rational explanation, despite Jellicoe having largely fulfilled his primary mission of combating the German U-boat threat to British merchant shipping. The outcome of the war may well have been affected if the level of shipping losses sustained through U-boat attack in April 1917 had continued unabated.
The central argument of the dissertation is that the dismissal was unjustified. As an adjunct, it argues that the received view of certain historians that Jellicoe was not successful as First Sea Lord is unwarranted and originates from severe post war critism of Jellicoe by those with a vested interest in justifying the dismissal, notably Lloyd George.
Supporting these arguments, the following assertions are made. Firstly, given the legacy Jellicoe inherited when joining the Admiralty, through the strategies adopted, organisational changes made and initiatives undertaken in anti-submarine weapons development, the progress made in countering the U-boat threat was notable. Secondly, the universal criticism directed at the Admiralty over the perceived delay in introducing a general convoy system for merchant shipping is not sustainable having regard to primary source documentation. Thirdly, incidents that occurred during the latter part of 1917, and suggested as being factors which contributed to the dismissal, can be discounted. Fourthly, Lloyd George conspired to involve General Haig, Commander of the British Forces France, and the press baron, Lord Northcliffe, in his efforts to mitigate any potential controversy that might result from Jellicoe’s removal from office. Finally, the arguments made by a number of commentators that the Admiralty performed better under Jellicoe’s successor, Admiral Wemyss, is misconceived
Klimatyczne uwarunkowania rozwoju agroturystyki w okresie zimowym na obszarze Polski nizinnej
No full textThe purpose of this article is to characterize thermal and snow conditions in terms of agro-tourism during the winter season in lowland areas of Poland. The author used the mean monthly temperature data and the number of days with a snow cover ≥ 1 cm from 53 first order meteorological stations in Poland. The period employed in this study covers 31 winter seasons and includes the years from 1970 until 2000. The following meteorological indices were used: mean winter air temperature (Dec.-Feb.), winter severity index (according to Paczos), mean monthly temperature of the coldest month, the number of months with temperature above freezing during the winter season, the total number of months with temperature above freezing, and the number of days with a snow cover ≥ 1 cm. This study confirmed clear mitigation of winter seasons – the mean temperature during this period increased and varied from 1.0°C in western Poland and the central Odra river valley to –2.0°C in the north and northeast parts of the country. When we compare this data with winters during the period 1950–1975 we can note that the values were lower, and ranged from 0.5°C and ––3.5°C, respectively. When we consider separate 15-year periods (1970/71–1984/85 and 1985/86–1999/2000) we can clearly see that the total number of months with below freezing temperatures decreased from 33 to 23. In the period 1985–2000 there were four winter seasons when above freezing temperatures were registered during each month.
This study confirms a statistically significant association between the mean winter air temperature and the degree of winter snowiness, which is expressed in the number of days with a snow cover ≥ 1 cm. This can be subsequently determined by the following formula: y = –11.71x + 35.036 (R = 0.8284). This particular association indicates that with a progressing climate change (increase in temperature) the number of days with a snow cover will decrease, which will obviously have a negative effect on snow conditions and, subsequently, winter sports. It also should be pointed out that the lack of snow cover will surely deteriorate the esthetic qualities of the landscapeCelem opracowania jest charakterystyka warunków termicznych i śnieżnych w okresie zimowym sprzyjających uprawianiu turystyki na obszarze Polski nizinnej. Wykorzystano średnie miesięczne wartości temperatury powietrza i liczby dni z pokrywą śnieżną o grubości ≥ 1 cm z 53 stacji meteorologicznych Polski z okresu 1970/1971–1999/2000. Obliczono średnią temperaturę okresu zimowego XII–III, stopień ostrości zimy wg Paczosa, ilość miesięcy z ujemną temperaturą powietrza w okresie zimowym, liczebność zim z dodatnią temperaturą powietrza we wszystkich miesiącach, ilość dni z pokrywą śnieżną ≥ 1 cm. Wykazano wyraźne złagodzenie zimy – jej średnia temperatura wzrosła i zmieniała się od 1,0°C na zachodzie Polski i w dolinie środkowej Odry do –2,0°C na jej północno-wschodnim krańcu w porównaniu z okresem 1950/51–1974/75, kiedy odpowiednie wartości wynosiły 0,5°C i –3,5°C. W 15-leciach 1970/71–1984/85 i 1985/86–1999/2000 liczba miesięcy o ujemnej temperaturze powietrza zmniejszyła się z 33 do 23. W 15-leciu 1985/86–1999/2000 pojawiły się cztery zimy o dodatniej temperaturze wszystkich miesięcy zimowych. Stwierdzono statystycznie istotny związek pomiędzy wartością średniej temperatury zimy a stopniem śnieżności zimy wyrażonym przez liczbę dni z pokrywą śnieżną ≥ 1cm określony równaniem: y = –11,71x + 35,036 (R = 0,8284). Zależność ta wskazuje, że wraz z postępującym ociepleniem klimatu będzie zmniejszała się liczba dni z pokrywą śnieżną, co wpłynie na pogorszenie się warunków do uprawiania różnych sportów zimowych związanych z obecnością pokrywy śnieżnej i negatywnie wpłynie na walory estetyczne krajobrazu
Producción científica y visibilidad de los investigadores de la Universidad Carlos III de Madrid en las bases de datos del ISI, 1997-2003
No full textLos objetivos planteados en esta tesis son conocer los hábitos de publicación de los investigadores adscritos a un conjunto de áreas/departamentos de la UC3M, durante el período 1997-2003, en las bases de datos del Institute for Scientific Information (ISI), identificando la calidad de las publicaciones recogidas (documentos propios y citas recibidas), medida ésta en términos de impacto y visibilidad, y relacionando esta calidad con los hábitos de publicación obtenidos.
La metodología utilizada en el trabajo ha requerido la aplicación conjunta de técnicas estadísticas (univariantes, bivariantes y multivariantes), y del análisis de redes sociales, para la construcción de indicadores bibliométricos unidimensionales y multidimensionales, tanto de la producción científica identificada como de las citas recibidas por la misma.
Entre las conclusiones del estudio destaca que tanto la producción como las citas recibidas en todas las áreas/departamentos analizados tienen una tendencia ascendente, que los trabajos se realizan habitualmente en colaboración, así como que las temáticas con mayor producción son Física y Matemáticas, que gran parte de la investigación se publica en revistas situadas en el primer cuartil del Journal Citation Reports (JCR), y que esta actividad investigadora recibe normalmente citas de revistas con igual o mejor posición en el JCR en función de su Factor de Impacto
Evidence for erbium-erbium energy migration in erbium(III) bis(perfluoro-p-tolyl)phosphinate
No full textCopyright 2008 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. This article appeared in Applied Physics Letters 92, 103303 (2008) and may be found at
Peak Car and Beyond: The Fourth Era of Travel
No full textThere is emerging evidence that personal daily travel, particularly by car, has ceased to grow in the developed economies. This can be attributed to saturation of demand, given high levels of access and choice now widely available, together with constraints on higher speeds. We are therefore at a time of transition from an era of growth of per capita travel to an era of stability, in which the future factors determining the growth of total travel demand are demographic — population growth, increasing longevity, and urbanisation. The peak car phenomenon, which marks this transition, is seen in successful cities that attract a growing population whose travel needs are increasingly met by investment in rail-based transport, the revival of which is a characteristic of the new era
The photolysis of cis-dichlorobis (ethylenediamine) cobalt(III) tetrafluoroborate in acetonitrile, 1979
No full textCis-dichlorobis(ethylenediamine)cobalt(III) tetra- fluoroborate in acetonitrile which was irradiated with 370 and 350 nm radiations isomerized to its transisomer. Spectrophotometric monitoring of the solution's optical spectrum indicated smooth conversion from starting material to product. The quantum yield for conversion from cis- to trans-dichlorobis(ethylenediamine)cobalt (III) tetrafluoroborate was determined. There was evidence against a free radical mechanism for this conversion. This reaction did not occur with longer wavelength radiations (500, 440 and 420 nm). Irradiation of a solution with 250 nm radiation showed photodecomposition to unknown product(s). The investigation of other mechanisms was inconclusive
Dr. J. Gordon Melton, Baylor Professor, is Doing Research on F.F. Bosworth: His investigation has taken him to the First Assembly of God Church in Dallas
No full textCopyright (c) 2019 by Roscoe Barnes III
#FFBosworthIn this blog post, the writer reports on some of the
current research being done on Pentecostal church history in Texas by Dr. J.
Gordon Melton, a professor at Baylor University. The article, which highlights
the significant role of F.F. Bosworth, also mentions earlier research by Carrie
W. Loftis, the author of First
Assembly of God Dallas: A History of First Assembly of
God- Dallas, Texas, 1912- 1992 (First Assembly of God, 1992).Note: For more information on F.F. Bosworth, follow
the Bosworth Matters blog at ffbosworth.strikingly.com
#ChristTheHealer #BosworthMatters</p
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