1,721,136 research outputs found
Horizontal Infection Prevention and Control. Interventions with high- and low-resources
No full textContains fulltext :
214388.pdf (Publisher’s version ) (Open Access)Radboud University, 25 mei 2019Promotor : Voss, A. Co-promotor : Wertheim, H.F.L
Performance Validation of Selective Screening Agars for Guiding Antimicrobial Prophylaxis in Patients Undergoing Prostate Biopsy
No full textThe objective of our study was to evaluate the performance of four selective media used for guidance of oral antibiotic prophylaxis in transrectal prostate biopsy. In this prospective validation study, we used MacConkey media with vancomycin plus one of the following antibiotics: ciprofloxacin (McC3+CIP/V), trimethoprim (McC3+TMP/V), fosfomycin (McC3+FOF/V), and amdinocillin-amoxicillin-clavulanic acid (McC3+MEC/V). First, clinical strains of Gram-negative bacilli (GNB) (n = 33) were evaluated for growth on the selective media. Thereafter, rectal swabs (n = 97) were randomly collected from residual material of fresh stool samples and plated on a growth control and the four selective media. Levels of recovery of GNB on the growth control and selective media were compared, and the MICs of the antibiotics used in this study were determined
Connecting the dots: challenges and solutions for antimicrobial resistance in neonates and children in humanitarian settings
No full textLeerboek microbiologie en infectieziekten
No full textIn dit boek wordt stilgestaan bij alle soorten infecties en alle aandachtsgebieden binnen de medische microbiologie. Het is gebaseerd op klinisch relevante groepen van infectieziekten, waarbij de nadruk is gelegd op die infectieziekten die een in Nederland en Vlaanderen werkzame arts regelmatig tegenkomt.
De vijfde druk is bijgewerkt op actuele onderwerpen zoals MERS, SARS, COVID-19, modellering, pandemic preparedness, vaccinatieontwikkeling en ook niet-farmacologische interventies. Dankzij de inbreng van Vlaamse redacteuren en auteurs is er ook specifieke aandacht voor resistentie en therapie in België. Vrijwel alle ziektebeelden worden toegelicht aan de hand van casuïstiek. De hoofdstukken zijn opnieuw ingedeeld en in ruime mate van illustraties voorzien.
Leerboek microbiologie en infectieziekten is primair bedoeld voor studenten geneeskunde en medische biologie, maar wordt ook binnen de studies tandheelkunde en mondzorg ingezet. Daarnaast is heteen handzaam naslagwerk voor de professional. Alle inhoud van dit boek is bovendien via de online leeromgeving beschikbaar.
Aan deze geactualiseerde en uitgebreide druk hebben specialisten van alle Nederlandse en Vlaamse geneeskundefaculteiten meegewerkt
The Effect of Different Types of Prostate Biopsy Techniques on Post-Biopsy Infectious Complications
No full textThe aim of our study was to compare infectious complication rates between different prostate biopsy techniques with various number of biopsy cores. In this retrospective study, all patients from 2 hospitals who underwent prostate biopsy between 2012 and 2019 were identified. Cohorts with different types of prostate biopsies were compiled within these hospitals. Primary outcome measure was any registered infectious complication within 7 days post-biopsy. Secondary outcomes were infectious complications within 30 days, hospitalization and bacteremia. To compare the risk of infection following different prostate biopsy techniques, data was fitted into a logistic regression model adjusting for potential confounders. In total, 4,233 prostate biopsies in 3,707 patients were included: TRUSPB 12±1.4 biopsy cores; transperineal magnetic resonance imaging (MRI)-ultrasound fusion guided prostate biopsy 16±3.7 biopsy cores; transrectal targeted MRI-ultrasound fusion guided prostate biopsy 3.1±0.8 biopsy cores; transrectal targeted in-bore MRI guided prostate biopsy 2.8±0.8 biopsy cores
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Online survey among Dutch urologists about prostate biopsy practices
No full textThe clinical landscape of prostate biopsy is evolving with changes in procedures and techniques. Moreover, antibiotic resistance is increasing and influences the efficacy of pre-biopsy prophylactic regimens. Therefore, increasing antibiotic resistance may impact on clinical care, which probably results in differences between hospitals. The objective of our study is to determine the (variability in) current practices of prostate biopsy in the Netherlands and to gain insight into Dutch urologists' perceptions of fluoroquinolone resistance and biopsy related infections. An online questionnaire was prepared using SurveyMonkey® platform and distributed to all 420 members of the Dutch Association of Urology, who work in 81 Dutch hospitals. Information about PB techniques and periprocedural antimicrobial prophylaxis was collected. Urologists' perceptions regarding pre-biopsy antibiotic prophylaxis in an era of antibiotic resistance was assessed. One hundred sixty-one responses were analyzed representing 65 (80.3%) of all Dutch hospitals performing prostate biopsy
Acceptability of innovative culture-based antibiotic prophylaxis strategies: a multi-method study on experiences regarding transrectal prostate biopsy
No full textThe acceptability of innovative medical strategies among healthcare providers and patients affects their uptake in daily clinical practice. To explore experiences of healthcare providers and patients with culturebased antibiotic prophylaxis in transrectal prostate biopsy with three swabscreening scenarios: self-sampling at home, self-sampling in the hospital and sampling by a healthcare provider. We performed focus group interviews with urologists and medical microbiologists from 11 hospitals and six connected clinical microbiological laboratories. We used Flottorp's comprehensive checklist for identifying determinants of practice to guide data collection and analysis. The experiences of 10 laboratory technicians from five laboratories and 452 patients from nine hospitals were assessed using a questionnaire. The database contains the results of the questionnaires sent to patients and the experiences of laboratory technicians
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