102,551 research outputs found

    Implementing cognitive behavioral therapy for chronic fatigue syndrome in clinical practice. An evaluation of processes and outcomes.

    No full text
    Contains fulltext : 80317.pdf (Publisher’s version ) (Open Access)The exact structures of large, biologically interesting molecules such as proteins are very important for the functions these molecules fulfill. In order to increase our understanding of the relationship between structure and function and to enhance the predictive power of theoretical models the structures of several small model systems have been determined very accurately. Each of these systems is closely related to important structural elements in proteins or DNA. The structure determination itself proceeds through irradiation of these molecules with UV laserlight and subsequent determination of the wavelengths which have been absorbed. From this analysis the rotational energy levels of the molecule can be determined, which are connected to its structure. It turns out that, above all, the structures of systems with multiple chemically weak bonds such as hydrogen bonds differ substantially from theoretical predictions. Since the overall shape of practically all larger biomolecules is determined by these types of bonds, this result has potentially large implications for the analysis of structure and function of biomolecules. The thesis features a comprehensive introduction to the field of high-resolution molecular spectroscopy, assuming a BSc. degree in physics, chemistry or related field. The six following chapters each describe a separate molecular system. These are the benzoic acid dimer (chapter 2), the clusters of phenol with one and two argon atoms (chapter 3), O-toluidine (chapter 4), the 7-azaindole one and two water clusters (chapter 5), the phenol dimer (chapter 6) and benzimidazole (chapter 7)RU Radboud Universiteit Nijmegen, 20 februari 2009Promotor : Bleijenberg, G. Co-promotor : Wensing, M.J.P.158 p

    Tearing down walls: opening the border between hospital and ambulatory care for quality improvement in Germany.

    No full text
    Item does not contain fulltextThe hospital benchmarking system in Germany was originally introduced to detect unintended consequences of reimbursement based on diagnosis-related groups. The new nationwide SQG programme aims to provide information on quality and outcomes of health care provided in hospital, ambulatory specialist and primary care settings, including the healthcare delivery across different sectors. In 2010 the topics for indicator development were cataract surgery, cervical conization, colectoral cancer and percutaneous coronary interventions or coronary angiography. A systematic stepwise modified RAND/UCLA procedure is applied to develop quality indicators in each of these domains. A general framework for data collection is implemented. Benchmarking results are fed back to providers on a regular basis.01 april 201

    Exploring the Limits of a Redundant Actuation System through Co-Design

    No full text
    This paper assesses the energy efficiency of a redundant actuation architecture combining Quasi-Direct Drive (QDD) motors and Series Elastic Actuators (SEAs) by comparing its energy consumption to Geared Motors (GMs) and SEAs alone. We consider this comparison for two robotic systems performing different tasks. Our results show that using the redundant actuation we can save up to 99% of energy with respect to SEA for sinusoidal movements. This efficiency is achieved by exploiting the coupled dynamics of the two actuators, resulting in a latching-like control strategy. We also show that these large energy savings are not straightforwardly extendable to nonsinusoidal movements, but smaller savings (e.g., 7%) are nonetheless possible. The presented results were obtained thanks to the framework of concurrent design (co-design), namely the simultaneous optimization of hardware parameters and control trajectories. This shows that the combination of complex hardware morphologies and advanced numerical co-design can lead to peak hardware performance that would be unattainable by human intuition alone

    Bibliographie Hilarion G. Petzold 1958 – 2009 mit Anhang als Einführung

    No full text
    Dieses Archiv enthält die Gesamtbibliographie der Werke des Autors nebst einiger Texte „Über H. G. Petzold“ im Schlussteil der Bibliographie sowie einen Anhang mit einer Einführung in die Architektur des Werkes in seinem wissenslogischen Aufbau als Ausarbeitung seines „Tree of Science Modells“ (2007).This archive contains the complete bibliography of the author and some texts about H. G. Petzold, moreover an epilogue with an introduction to the architecture of the works in its epistemological structure and composition and as an elaborations of Petzold’s „Tree of Science Modell (2007).https://www.fpi-publikation.de/polyloge/01-2009-petzold-h-g-gesamtbibliographie-h-g-petzold-1958-2009-updating-november2009/peerReviewedpublishedVersio

    Dispelling the Myths Behind First-author Citation Counts

    No full text
    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Development of limited-view tomography for measurement of Spray G plume direction and liquid volume fraction

    No full text
    The method for direct injection of fuel in the cylinder of an IC engines is important to high-efficiency and low-emission performance. Optical spray diagnostics plays an important role in understanding plume movement and interaction for multi-hole injectors, and providing baseline understanding used for computational optimization of fuel delivery. Traditional planar or line-of-sight diagnostics fail to capture the liquid distribution because of optical thickness concerns. This work proposes a high-speed (67 kHz) extinction imaging technique at various injector rotations coupled to computed tomography (CT) for time-resolved reconstruction of liquid volume fraction in three dimensions. The number of views selected and processing were based on synthetic (modeled) liquid volume fraction data where extinction and CT adequately reconstructed each plume. The exercise showed that for an 8-hole, symmetric-design injector (ECN Spray G), only three different views are enough to reproduce the direction of each plume, and particularly the mean plume direction. Therefore, the number of views was minimized for experiments to save expense. Measurements applying this limited-view technique confirm plume-plume variations also detected with mechanical patternation, while providing better spatial and temporal resolution than achieved previously. Uncertainties due to the limited view within pressurized spray chambers, the droplet size, and optically thick regions are discussed.

    Assessment of five oblique radiographic projections of the canine temporomandibular joint

    No full text
    Investigation of temporomandibular joint (TMJ) disease requires a clear diagnostic image, which can be challenging to obtain using conventional radiography. The aim of this study was to compare five different oblique radiographic views with the head in lateral recumbency, assessing the clarity of visualization of the normal TMJ anatomy. The views under investigation were the laterorostral–laterocaudal oblique at a 10° and 20° rotation of the head (“nose-up” view), laterorostral–laterocaudal oblique with a rostrocaudal X-ray beam angulation of 10° and 20°, and a parallax view with the beam centered over C2 and collimated to include the TMJ region, using the divergence of the X-ray beam to project the TMJs separately on the radiograph. The views were performed on both TMJs of thirty canine cadavers and were graded independently by experienced and inexperienced observers. Grading was performed on the mandibular fossa, condylar process, joint space, retroarticular process, and the overall TMJ, and was based on a four-point scale. Mean grades for each component and for the overall joint were compared for each observer and each projection. Mean grades were significantly (P < 0.05) higher for the “Nose-up” projections than the angled beam or parallax projections, as was interobserver agreement, and both observers showed significantly higher (P < 0.05) mean grades for the 20o “Nose-up” angulation than the 10o “Nose-up” angulation. These results suggest that a latero 20o rostral–laterocaudal oblique gives the best representation of the anatomy of the TMJ of the dog of the projections assessed, and should be considered when investigating clinical cases of TMJ disease

    Author-springer.pdf

    No full text
    guilguniluhjkjgjkjhnkjgj hujkk gjk hioyhiu ug gg g
    corecore