689 research outputs found
S3_File._STARD-2015-checklist – Supplemental material for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study
No full textSupplemental material, S3_File._STARD-2015-checklist for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study by Ting Yu, Ligui Wu, Ling Yuan, Robert Dawson, Rongmei Li, Zhenzhu Qiu, Xiancui Wu, Ping Chen, Jing Qi, Yiqun Yang, Yuling Feng, Wei Xu, Weiwei Kong, Yang Chen, Shanping Li, Xiang Wu and Tingting Yan in The Journal of Vascular Access</p
S2_File._STROBE-statement – Supplemental material for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study
No full textSupplemental material, S2_File._STROBE-statement for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study by Ting Yu, Ligui Wu, Ling Yuan, Robert Dawson, Rongmei Li, Zhenzhu Qiu, Xiancui Wu, Ping Chen, Jing Qi, Yiqun Yang, Yuling Feng, Wei Xu, Weiwei Kong, Yang Chen, Shanping Li, Xiang Wu and Tingting Yan in The Journal of Vascular Access</p
S1_File._CONSORT-2010-Checklist – Supplemental material for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study
No full textSupplemental material, S1_File._CONSORT-2010-Checklist for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study by Ting Yu, Ligui Wu, Ling Yuan, Robert Dawson, Rongmei Li, Zhenzhu Qiu, Xiancui Wu, Ping Chen, Jing Qi, Yiqun Yang, Yuling Feng, Wei Xu, Weiwei Kong, Yang Chen, Shanping Li, Xiang Wu and Tingting Yan in The Journal of Vascular Access</p
S4_File._Numbers_of_initially_PICC_insertion_patients – Supplemental material for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study
No full textSupplemental material, S4_File._Numbers_of_initially_PICC_insertion_patients for The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study by Ting Yu, Ligui Wu, Ling Yuan, Robert Dawson, Rongmei Li, Zhenzhu Qiu, Xiancui Wu, Ping Chen, Jing Qi, Yiqun Yang, Yuling Feng, Wei Xu, Weiwei Kong, Yang Chen, Shanping Li, Xiang Wu and Tingting Yan in The Journal of Vascular Access</p
Two-year responses of heart rate and heart rate variability to first occupational lead exposure
No full textObjective: Because of the falling lead exposure, the literature relating autonomous nervous function to blood lead has limited relevance. Design and method: In the longitudinal Study for Promotion of Health in Recycling Lead (URL: https://www.clinicaltrials.gov; Unique identifi er: NCT02243904), we recorded the 2-year responses of heart rate, heart rate variability (Cardiax, International Medical Equipment Developing, Budapest, Hungary), and median nerve conduction velocity (Brevio, NeuMed, West Trenton, NJ), a routine test in occupational medicine, to fi rst lead exposure in 195 newly hired workers (91.3% men; mean age, 27.8 years). High-and low-frequency heart rate variability power and orthostatic heart rate variability responses were derived from 5-minute eletrocar-diograms in the supine and standing positions by Fourier transform and autoregres-sion. Blood lead was determined by inductively coupled plasma mass spectrometry. Results: From baseline to follow-up, blood lead increased from 4.22 to 14.1 ug/dL and supine/standing HR from 63.6/75.5 to 67.1/78.8 beats per minute. In analyses stratifi ed by fourths of blood lead changes, trends in heart rate and Fourier/autore-gressive heart rate variability did not reveal a dose-response curve (0.074 3-fold blood lead increment did not affect autonomous neural function as captured by heart rate variability. CARDIOVASCULAR RISK AND SUBCLINICAL VASCULAR ORGAN DAMAGE IN PATIENTS WITH AND WITHOUT HYPERTENSION Objective: Assessment of subclinical organ damage and sex differences in car-diovascular risk stratifi cation in patients with or without hypertension. Design and method: We divided 100 patients in two groups: HT+: patients with arterial hypertension (25 women and 25 men); HT-: patients without arterial hy-pertension (25 women and 25 men). The average age of them [yrs]: 56 and 53 (*p < 0,05). Ankle-brachial index (ABI), pulse wave velocity (PWV) and carotid intima-media thickness (IMT) were evaluated. We assessed cardiovascular risk according to: SCORE and Framingham scales. Statistical calculations were performed in PQStat 1.6. For comparison of variables we used the t-test for unrelated samples. To perform the correlation we used Spearman's rank correlation RS. Results: We revealed following results in both groups: HT+ and HT-respectively [*for p< = 0,05; **for p < 0,001; NS-negligible statistically]. In the group with hypertension women were characterized by a lower IMT and PWV than men. The cardiovascular risk according to risk SCORE and Framing-ham scales in men was signifi cantly higher than in women in both groups. In female with hypertension, there was a signifi cant negative correlation between ABI and IMT. In male without hypertension, there was a signifi cant negative correlation between ABI and IMT. Conclusions: 1. There was no difference in values of: ABI, PWV and IMT between the sexes in normotensive patients. 2. Women with hypertension were characterized by a lower IMT and PWV. 3. There were signifi cant negative correlation between ABI and IMT in female and male groups
2D fin field-effect transistors integrated with epitaxial high-k gate oxide
No full textPrecise integration of two-dimensional (2D) semiconductors and high-dielectric-constant (k) gate oxides into three-dimensional (3D) vertical-architecture arrays holds promise for developing ultrascaled transistors1–5, but has proved challenging. Here we report the epitaxial synthesis of vertically aligned arrays of 2D fin-oxide heterostructures, a new class of 3D architecture in which high-mobility 2D semiconductor fin Bi2O2Se and single-crystal high-k gate oxide Bi2SeO5 are epitaxially integrated. These 2D fin-oxide epitaxial heterostructures have atomically flat interfaces and ultrathin fin thickness down to one unit cell (1.2 nm), achieving wafer-scale, site-specific and high-density growth of mono-oriented arrays. The as-fabricated 2D fin field-effect transistors (FinFETs) based on Bi2O2Se/Bi2SeO5 epitaxial heterostructures exhibit high electron mobility (μ) up to 270 cm2 V−1 s−1, ultralow off-state current (IOFF) down to about 1 pA μm−1, high on/off current ratios (ION/IOFF) up to 108 and high on-state current (ION) up to 830 μA μm−1 at 400-nm channel length, which meet the low-power specifications projected by the International Roadmap for Devices and Systems (IRDS)6. The 2D fin-oxide epitaxial heterostructures open up new avenues for the further extension of Moore’s law. © 2023, The Author(s), under exclusive licence to Springer Nature Limited.11Nsciescopu
Emerging integrated SERS-microfluidic devices for analysis of cancer-derived small extracellular vesicles
No full textCancer-derived small extracellular vesicles (sEVs) are specific subgroups of lipid bilayer vesicles secreted from cancer cells to the extracellular environment. They carry distinct biomolecules (e.g., proteins, lipids and nucleic acids) from their parent cancer cells. Therefore, the analysis of cancer-derived sEVs can provide valuable information for cancer diagnosis. However, the use of cancer-derived sEVs in clinics is still limited due to their small size, low amounts in circulating fluids, and heterogeneous molecular features, making their isolation and analysis challenging. Recently, microfluidic technology has gained great attention for its ability to isolate sEVs in minimal volume. In addition, microfluidics allows the isolation and detection of sEVs to be integrated into a single device, offering new opportunities for clinical application. Among various detection techniques, surface-enhanced Raman scattering (SERS) has emerged as a promising candidate for integrating with microfluidic devices due to its ultra-sensitivity, stability, rapid readout, and multiplexing capability. In this tutorial review, we start with the design of microfluidics devices for isolation of sEVs and introduce the key factors to be considered for the design, and then discuss the integration of SERS and microfluidic devices by providing descriptive examples of the currently developed platforms. Lastly, we discuss the current limitations and provide our insights for utilising integrated SERS-microfluidics to isolate and analyse cancer-derived sEVs in clinical settings.Long Ngo, Le Que Anh Pham, Anastasiia Tukova, Amin Hassanzadeh-Barforoushi, Wei Zhang and Yuling Wan
The Role of Facial Enhancement Technology in Online Sales of Branded Color Cosmetics
No full textThe Role of Facial Enhancement Technology in Online Sales of Branded Color Cosmetics
This is an article-based dissertation. The author conducted three published studies to support this dissertation during her PhD studies. It includes three quantitative studies. The purpose of this dissertation is multifold: First, to explore the factors that may contribute to FET adoption. Second, to investigate the extent to which FET adoption contributes to subsequent online purchases (i.e., color cosmetics). Despite its strategic importance, the existing body of literature specifically discussing the essential role of AR-based FET on consumers’ behavioral intentions is still scarce (Javornik, 2016; Wang et al., 2022). Additionally, the customers’ adoption rate of FET is still relatively low with an unproven conversion rate on a mass scale (Monteros, 2021). The mechanisms by which users adopt FET and whether FET contributes to the online purchase intention of branded color cosmetics are still less explored.
To interconnect these three studies, the dissertation adopts the UTAUT theoretical model as the foundational framework, which was utilized in Study 3. The unified theory of acceptance and use of technology (UTAUT) developed by Venkatesh et al. (2003) is one of the most popular theories for explaining behavioral intentions to adopt new technology. The primary contribution of this dissertation is to extend the traditional UTAUT model (Venkatesh et al., 2003) and apply it in the context of FET. More specifically, UTAUT is used as a baseline model in this dissertation since it can be leveraged to examine determinants of AI adoption (Venkatesh, 2022) such as FET.
In this dissertation, the author primarily employed a quantitative online survey as the core research methodology, employing purposive and snowball sampling techniques for data collection. The sample populations varied across the studies: Study 1 focused on Chinese social media influencers (N=221), Study 2 on Indonesian FET users (N=262), and Study 3 on Chinese FET users (N=473). The dissertation investigated six independent variables (performance expectancy, effort expectancy, social influence, facilitating conditions, body esteem, and price sensitivity), one dependent variable (online purchase intention), one mediator (facial enhancement technology adoption), and one moderator (social media addiction). In total, eight construct-level hypotheses were tested throughout the dissertation. The constructs were measured using a five-point Likert scale ranging from “strongly disagree” (1) to “strongly agree” (5). All three selected studies utilized Structural Equation Modeling (SEM) via SPSS and AMOS software for data analysis. A 2-step approach, comprising Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA), was implemented to validate the hypotheses and generate the results.
This dissertation adapted UTAUT as the theoretical foundation, the main findings primarily stem from Study 3. Some relevant findings from Studies 1 and 2 are also presented, helping to shape the research model for the dissertation. For instance, body esteem was tested in the relationship with FET adoption in Study 1 and Study 2. In Study 1, body esteem was not found to be a significant predictor of FET adoption, whereas in Study 2, both positive and negative views of body esteem exhibited a positive relationship with FET adoption. These results inspired the author to include both positive and negative body esteem in the final dissertation model.
This dissertation has several theoretical contributions: First, this dissertation introduces a new concept, namely facial enhancement technology (FET). FET was used as an umbrella term in this dissertation to refer to artificial intelligence (AI), augmented reality (AR), and virtual reality (VR) technologies capable of altering users' facial features in a virtual environment. Second, this dissertation’s primary theoretical contribution is to identify the antecedents of FET adoption and how it may lead to online purchases of branded color cosmetics. Third, this dissertation adds to the body of knowledge in social comparison theory by elucidating the roles of body esteem and online purchase behavior in the context of FET adoption, a relatively new innovation in interactive technology. Lastly, this dissertation introduces social media addiction as a moderating variable. To the best of our knowledge, this is the first dissertation to propose and provide empirical evidence of the moderating role of social media addiction in the relationship between FET and online purchases
A Web Services Selection Method based on the QoS Probability Distribution
No full textService-Oriented Architecture (SOA) provides a flexible framework for service composition. A composite web service is represented by a workflow, and for each task within the workflow, several candidate Web services which offer the same functionality may be available. In previous work (Hwang, Hsu, & Lee, 2014), Hwang et al. propose a service selection framework based on probabilistic QoS distributions of component services. Their method decomposes a global QoS constraint into a number of local constraints using the average QoS value of each candidate service. However, heterogeneous deviation among candidate services may lead to the suboptimal selection. We propose an initial service assignment finding method with considering the standard deviation of QoS distributions. The objective of service selection is to maximize the global QoS conformance. Experimental results show that the proposed approach significantly improves the performance in probabilistic QoS-based service selection method, in terms of both global QoS conformance and running time
A Framework for Discovering Opinions on Issues From User Generated Content: Using Cross-Strait Agreement on Trade in Services as an Example
No full textUser generated content (UGC) is increasing quickly due to the advance of information technology. A post about enterprise finance condition or social political issue in forums is part of UGC. Nowadays applying text mining and sentiment analysis techniques on UGC has been shown to be a promising alternative to the traditional polls. In this work, we propose a framework for discovering opinions on issues discussed on forums, specifically those related to Cross-Strait Agreement on Trade in Services. In particular, we identify issues by finding frequent nouns and then discover the pertaining opinions on the posts. Over Fifteen thousand posts on PTT forums are processed using the proposed approach. Finally, we discover that the overall emotion on various issues tend to be negative, whereas the amount of discussion and the degree of negative emotions vary dramatically
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