1,720,964 research outputs found
KARAKTERISTIK PENDERITA TUMOR SISTEM REPRODUKSI WANITA DENGAN PEMERIKSAAN HISTOPATOLOGI DI RUMAH SAKIT UMUM MADANI MEDAN PERIODE TAHUN 2018 – 2022
Get PDFTumor sistem reproduksi wanita merupakan jenis sel tumor yang dapat tumbuh di berbagai organ sistem reproduksi wanita. Berdasarkan data Rikesdas, pravelensi tumor di Indonesia tahun 2018 terdapat 1.017.290 (1,79%) dari 278,8 juta penduduk. Tujuan penelitian untuk mengetahui karakteristik penderita tumor sistem reproduksi wanita dengan pemeriksaan histopatologi di Rumah Sakit Umum Madani Medan Periode Tahun 2018–2022. Jenis penelitian menggunakan pendekatan deskriptif retrospektif, sumber data yang diambil data sekunder yaitu rekam medik dengan metode total sampling sebanyak 234 orang. Analisis hasil penelitian dilakukan dengan analisis statistik frekuensi menggunakan SPSS. Berdasarkan kelompok usia terbanyak yang mengalami tumor sistem reproduksi wanita adalah usia 36-45 tahun sebanyak 103 orang (44,0%), berdasarkan diagnosa histopatologi terbanyak adalah Leiomyoma Uteri sebanyak 129 orang (55,1%), berdasarkan jenis tumor terbanyak adalah tumor jinak sebanyak 234 orang (100%), berdasarkan lokasi tumor terbanyak adalah tumor uterus sebanyak 131 orang (56,0%). Penderita Endometriosis mayoritas berada pada kelompok usia 26–35 tahun sebanyak 16 orang (14,6%), penderita Leiomyoma Uteri mayoritas berusia 36-45 tahun sebanyak 64 orang (62,1%), penderita Mucinous Cystadenoma Ovarii mayoritas berusia 36–45 tahun sebanyak 13 orang (12,6%), penderita Serous Cystadenoma Ovarii mayoritas berusia 36–45 tahun sebanyak 8 orang (7,8%), dan penderita Mature Teratoma mayoritas berusia 26–35 tahun sebanyak 9 orang (2,9%). Mayoritas penderita yang mengalami tumor jinak berada pada kelompok usia 36–45 tahun sebanyak 103 orang (100%). Mayoritas penderita yang mengalami tumor jinak adalah tumor Leiomyoma Uteri sebanyak 129 orang (100%)
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Histopathological characteristics of breast tumors at Madani General Hospital Medan
No full textCytology and histopathology include examinations to diagnose breast tumors. The diagnosis of advanced stages of breast tumors can lead to reduced therapeutic options and success. This study aimed to describe the results of cytological and histopathological examinations of patients with breast tumors at the Anatomical Pathology Laboratory of Madani Medan General Hospital between the period 2018-2022. This study was descriptive and retrospective. The study population included all the medical records of patients diagnosed with breast tumors. The research sample consisted of the medical records of patients with FAM and Carcinoma Mammae obtained by consecutive sampling. The results of cytological and histopathological examinations showed that the majority of breast tumor patients were both aged 17-25 years with a percentage of 42.9% and 52.4%, respectively). The results of the cytological examination showed that the majority of patients had benign tumor diagnoses (85.7%) and histology (90.5%). Malignant tumors were diagnosed based on the results of cytological examination (14.3%) and histology (9.5%). Based on the relationship between age. Based on the relationship between age and diagnosis of benign and malignant tumors, the results of cytological examination showed that patients aged 12-16 years, 17-25 years, and 26-35 years all had benign tumors (100%), patients aged 36-45 years had benign tumors (50.0%) and malignant tumors (50.0%), and patients aged 56-65 years all had malignant tumors (100.0%). Histopathological examination results showed that patients aged 12-16 years, 17-25 years, 26-35 years, and 36-45 years all had benign tumors (100%), patients aged 46-55 years had benign tumors (50.0%) and malignant tumors (50.0%), and patients aged 56-65 years all had malignant tumors (100.0%)
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Cerebral Histopathology in Acute Toxicity Test of Curcuma Zedoria
Get PDFThis research aims to determine the effect of the acute toxicity test of white turmeric extract (Curcuma zedoaria) on the brain organ. This research is experimental research with a Post Test Only Control Group Design. This research was conducted at the Pharmacy and Histology Laboratory. Faculty of Medicine. University of North Sumatra. The research was carried out from January to March 2023. The population in this research involved male white rats (Rattus norvegicus). The results of the acute toxicity test of white turmeric extract for 14 days showed no signs of toxicity or death in rats given the smallest to largest doses, resulting in an apparent LD50 value of white turmeric extract is >2 g/kgBW, and is classified in the practically non-toxic category. Rats that received white turmeric extract showed movement or activity, appearing more energetic by the end of the second week with increasing doses. Histopathological examination of the brain in the acute toxicity test revealed minimal changes, such as edema and congestion in line with increasing doses.This research aims to determine the effect of the acute toxicity test of white turmeric extract (Curcuma zedoaria) on the brain organ. This research is experimental research with a Post Test Only Control Group Design. This research was conducted at the Pharmacy and Histology Laboratory, Faculty of Medicine, University of North Sumatra. The research was carried out from January to March 2023. The population in this research involved male white rats (Rattus norvegicus). The results of the acute toxicity test of white turmeric extract for 14 days showed no signs of toxicity or death in rats given the smallest to largest doses, resulting in an apparent LD50 value of white turmeric extract is >2 g/kgBW, and is classified in the practically non-toxic category. Rats that received white turmeric extract showed movement or activity, appearing more energetic by the end of the second week with increasing doses. Histopathological examination of the brain in the acute toxicity test revealed minimal changes, such as edema and congestion in line with increasing doses
TOXICITY TEST OF WHITE TURMERIC (CURCUMA ZEDOARIA) ON LIVER ORGANS IN WHITE MALE RATS
Get PDFAbstractWhite turmeric is often used by the people of Indonesia as an herbal plant that has many benefits for the body, one of which is for the liver. But there are still many people who do not know the right and correct dosage in using this white turmeric. The purpose of this study was to determine the toxic dose of white turmeric extract to estimate the degree of damage caused by the extract to the liver. This research design uses experimental research methods by means of Post Test Only Control Group Design. The sample used in this study consisted of 5 rats in each group with a number of groups of rats consisting of 6 groups with a total sample of 30 male white rats of the Wistar strain and in each group different treatments were carried out. Sampling was done using the Simple Random Sampling technique. Rats were divided into 2 control groups, namely equates negative control and NaCMC positive control, and also 4 treatment groups with a dose of 250 mg/kg BW, 500 mg/kg BW, 750 mg/kg BW, and 2000 mg/kg BW. From the results, it was found that the histopathological picture of the control group did not show significant changes, but in the treatment group, the doses of 250 mg/kg BW and 500 mg/kg BW were very clear where there was a lot of severe damage and hydrophilic degeneration began to occur where cell swelling, vacuoles were also found. fat. However, this happens because the liver sample already has a history of disease so that it gives a picture of degeneration. Keywords: acute toxicity test, extract of white turmeric (Curcuma zedoaria), liver histopathology, male white rat Wistar strain Abstrak Kunyit putih sering sekali digunakan oleh masyarakat Indonesia sebagai tanaman herbal yang memiliki banyak manfaat bagi tubuh, salah satunya bagi organ hati. Tetapi masih banyak masyarakat yang belum mengetahui dosis yang tepat dan benar dalam menggunakan kunyit putih ini. Tujuan dilakukannya penelitian untuk mengetahui dosis toksik dari ektrak kunyit putih untuk memperkirakan derajat kerusakan yang diakibatkan oleh ektrak tersebut terhadap organ hati. Rancangan penelitian ini menggunakan metode penelitian eksperimental dengan cara Post Test Only Control Group Design. Sampel yang digunakan dalam penelitian ini terdiri dari 5 ekor tikus setiap kelompok dengan jumlah kelompok tikus terdiri dari 6 kelompok dengan jumlah total sampel 30 tikus putih jantan jenis galur wistar dan di setiap kelompok dilakukan perlakuan yang berbeda- beda. Pengumpulan sampel dilakukan menggunakan teknik Simple Random Sampling. Tikus dibagi menjadi 2 kelompok kontrol yaitu kontrol negatif aquades dan kontrol positif NaCMC, dan juga 4 kelompok perlakuan dengan dosis 250 mg/KgBB, 500 mg/KgBB, 750 mg/KgBB, dan 2000 mg/KgBB. Dari hasil di dapatkan bahwa gambaran histopatologi kelompok kontrol tidak menunjukkan perubahan yang signifikan, tetapi pada kelompok perlakuan dosis 250 mg/KgBB dan 500 mg/KgBB terlihat sangat jelas dimana banyak kerusakan yang berat dan mulai terjadi degenarasi hidrofilik dimana pembengkakan sel, adanya di jumpai juga vakuola lemak. Namun hal ini terjadi kemungkinan sampel hati sudah memiliki riwayat penyakit sehingga memberikan gambaran degenerasi. Tetapi pada dosis 750 mg/KgBB dan 2000 mg/KgBB dijumpai sel yang mulai membaik dengan menunjukkan adanya perbaikan dimana berkurangnya degenerasi parenkimatosa dan degenerasi hidrofik tetapi masih dijumpai kelainan hati yang abnormal yaitu masih adanya pembengkakan pada sel-sel. Dengan kesimpulan semakin tinggi diberikan dosis dalam perlakuan maka memberikan efek yang positif atau baik terhadap perbaikan kerusakan hati. Keywords: uji toksisitas akut, ekstrak kunyit putih (Curcuma zedoaria), histopatologi hati, tikus putih jantan galur wistar
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