102,266 research outputs found
"The Consolidated Assistance Program, Reforming Welfare by Synchronizing Public Assistance Benefits"
No full textLevin-Waldman examines the structure of existing welfare programs and concludes that the current array of benefits could be synchronized and consolidated to create a new system that would provide economic incentives to work. He suggests combining elements of the earned income tax credit (EITC) and current welfare programs into one program, a consolidated assistance program (CAP). Levin-Waldman argues that a program composed of an assistance component (with one set of benefits for working parents and a different set for nonworking parents) and a child support component could be designed to assure minimal subsistence to those unable to work while providing incentives for those on welfare to work without, in effect, penalizing them for getting off welfare. Such a program would reform welfare more expeditiously than a plan that would simply expand the EITC or put a time limit on welfare benefits. Moreover, such a plan would not necessarily add to the national budget deficit.
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Observation of Two-Neutrino Double-Beta Decay in 136Xe with the EXO-200 Detector
No full textWe report the observation of two-neutrino double-beta decay in [superscript 136]Xe with T[subscript 1/2]=2.11±0.04(stat)±0.21(syst)×10[superscript 21] yr. This second-order process, predicted by the standard model, has been observed for several nuclei but not for [superscript 136]Xe. The observed decay rate provides new input to matrix element calculations and to the search for the more interesting neutrinoless double-beta decay, the most sensitive probe for the existence of Majorana particles and the measurement of the neutrino mass scale.National Science Foundation (U.S.)United States. Dept. of EnergyNatural Sciences and Engineering Research Council of Canada (NSERC)Swiss National Science FoundationRussian Foundation for Basic Researc
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Case report: Treatment of burning pain and Post traumatic refractory Allodynia in foot digits, with low dose of ketamine
No full textFrequent simulation and irritation of NMDA receptors by glutamate mediators can lead to
burning pain, allodynia and hyperalgesia, even after stopping the irritant factor. Opioid-induced
hyperalgesia and peripheral nerve injuries in lower extremities orthopedic surgeries can also
make the same symptoms, which sometimes make it difficult to diagnose it from causalgia (type
II complex regional pain syndrome). Post-traumatic neuralgia is not so common, often does not
respond well to usual medications and prolongs the patient’s stay in hospital. Noting the
anatomical and physiological aspects of pain transmission pathways and also role of pain
transmission inhibitors via NMDA receptors in pain management, opens us a new window to the
role of medicines such as ketamine in prevention and treatment of neuropathic or chronic postoperative
pains. We report a case involving refractory neuropathic pain which is eventually
controlled with low dose of ketamine
- …
