48,024 research outputs found

    Diagnosis of hyperthyroidism in cats with mild chronic kidney disease

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    OBJECTIVES: In cats with concurrent hyperthyroidism and non-thyroidal illnesses such as chronic kidney disease, total thyroxine concentrations are often within the laboratory reference range (19 to 55 nmol/l). The objective of the study was to determine total thyroxine, free thyroxine and/or thyroid-stimulating hormone concentrations in cats with mild chronic kidney disease. METHODS: Total thyroxine, free thyroxine and thyroid-stimulating hormone were measured in three groups. The hyperthyroidism-chronic kidney disease group (n=16) had chronic kidney disease and clinical signs compatible with hyperthyroidism but a plasma total thyroxine concentration within the reference range. These cats were subsequently confirmed to be hyperthyroid at a later date. The chronic kidney disease-only group (n=20) had chronic kidney disease but no signs of hyperthyroidism. The normal group (n=20) comprised clinically healthy senior (> 8 years) cats. RESULTS: In 4 of 20 euthyroid chronic kidney disease cats, free thyroxine concentrations were borderline or high (>= 40 pmol/l). In the hyperthyroidism-chronic kidney disease group, free thyroxine was high in 15 of 16 cats, while thyroid-stimulating hormone was low in 16 of 16 cats. Most hyperthyroidism-chronic kidney disease cats (14 of 16) had total thyroxine greater than 30 nmol/l, whereas all the chronic kidney disease-only cats had total thyroxine less than 30 nmol/l. CLINICAL SIGNIFICANCE: The combined measurement of free thyroxine with total thyroxine or thyroid-stimulating hormone may be of merit in the diagnosis of hyperthyroidism in cats with chronic kidney disease

    Mosaic maternal uniparental disomy of chromosome 11 in a patient with Silver-Russell syndrome

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    Silver-Russell syndrome (SRS) is a clinically heterogeneous disorder characterised mainly by intrauterine and postnatal growth retardation. While maternal uniparental disomy of chromosome 7 is found in 5-10% of SRS patients, recently genetic and epigenetic mutations affecting the imprinting centres on chromosome 11p15 have been reported in up to 64% of patients. Chromosome 11p15 abnormalities reported in SRS include methylation defects in the imprinting centre 1 (ICR1) and maternally inherited duplications involving all or part of the imprinted region of 11p15. Here we report the first published case of SRS with mosaic maternal uniparental disomy of chromosome 11

    A 2 h periodic variation in the low-mass X-ray binary Ser X-1

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    Spectroscopy of the low-mass X-ray binary Ser X-1 using the Gran Telescopio Canarias have revealed a ?2 h periodic variability that is present in the three strongest emission lines. We tentatively interpret this variability as due to orbital motion, making it the first indication of the orbital period of Ser X-1. Together with the fact that the emission lines are remarkably narrow, but still resolved, we show that a main-sequence K dwarf together with a canonical 1.4 M? neutron star gives a good description of the system. In this scenario, the most likely place for the emission lines to arise is the accretion disc, instead of a localized region in the binary (such as the irradiated surface or the stream-impact point), and their narrowness is due instead to the low inclination (?10°) of Ser X-1

    Mesophilic-hydrothermal-thermophilic (M-H-T) digestion of green corn straw

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    Mesophilic-hydrothermal (80-160 degrees C, 30 min)-thermophilic (M-H-T) digestion and control tests of mesophilic (M), thermophilic (T), hydrothermal-mesophilic (H-M), and mesophilic-thermophilic digestion (M-T) of green corn straw were conducted for a 20-day fermentation period. The results indicate that M-H-T is an efficient method to improve methane production. A maximum methane yield of 371.74 mL/g volatile solid was obtained by the M (3 days)-H (140 degrees C)-T (17 days) process, which was 20.44%, 16.55%, 31.44%, and 14.31% higher than the yields of the M, T, 140-M, and M-T processes. The enhanced methane production was attributed to (1) the improved hemicellulose degradation and lignin disorganization; (2) prevention of the degradation of soluble sugar, easily hydrolyzed hemicellulose and cellulose into furfural and methylfurfural; and (3) lack of formation of Maillard reaction products during initial hydrothermal treatment. (C) 2015 Elsevier Ltd. All rights reserved

    Contribution of Information and Communication Technology (ICT) in Country’S H-Index

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    The aim of this study is to examine the effect of Information and Communication Technology (ICT) development on country’s scientific ranking as measured by H-index. Moreover, this study applies ICT development sub-indices including ICT Use, ICT Access and ICT skill to find the distinct effect of these sub-indices on country’s H-index. To this purpose, required data for the panel of 14 Middle East countries over the period 1995 to 2009 is collected. Findings of the current study show that ICT development increases the H-index of the sample countries. The results also indicate that ICT Use and ICT Skill sub-indices positively contribute to higher H-index but the effect of ICT access on country’s H-index is not clear.Cite as: FARHADI, M., SALEHI, H., EMBI, M. A., FOOLADI, M., FARHADI, H., AGHAEI CHADEGANI, A., & ALE EBRAHIM, N. (2013). Contribution of Information and Communication Technology (ICT) in Country’S H-Index. Journal of Theoretical and Applied Information Technology, 57(1), 122-127

    Lah–Ribarič type inequalities for (h, g; m)-convex functions

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    Recently introduced new class of (h, g; m)-convex functions unifies a certain range of convexity, thus allowing the generalizations of know results. In this paper we prove Lah–Ribarič type inequalities for (h, g; m)-convex functions from which we obtain inequalities of Hermite–Hadamard, Fejér, Giaccardi, Popoviciu and Petrović. © 2021, The Author(s) under exclusive licence to The Royal Academy of Sciences, Madrid

    Mrs. H. M. Evers

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    Newspaper Article - 'Mrs. H. M. Evers' - Mrs. Evers hopes she can learn much about the living conditions here and the possibilities for the Dutch settlers.Alberta Women's Institutes; AWI CollectionMRS. H. M. EVERS I bring out his capital immediately and until such time as their cap­ital is released things are quite difficult. "' There are very few provinces in Canada that will sup­ply the Dutch settlers with a loan", Mr. Jensma stated. On her arrival here Mrs. Evers i was astounded at the unusua1. building of the city and the large • ields of wheat. " Of course we have wheat too, but ours is only a small country so we have to be very economical and not spend out land too freely". The buildings are much taller and narrower, es­pecially in the cities. Wood is very expensive so most of the homes are built of brick and concrete with corrugated steel and tile roofs. Give True Picture In her travels across the country Mrs. Evers hopes she can lenrn much about the living conditions here and the possibilities for the Dutch settlers so when she re- | turns to her homeland she will b- i able to give the women of Holland all the information possible and prepare them for their great ad­venture. Mrs. Evers and her family re­side on a 150 acre farm in the northern part of the country. Her daughter Tjaakje is a teacher in home economics and her son. Luken, works on the farm. Besides serving on the immigra­tion board she is a member of the international board of the YWCA; the international Council of Wo­men: international corporation of Dutch Country Wives: the inter­national organization of the As­sociated Country Women of thr World: and a member of the Wo­men's Institutes. She will leave on Tuesday for Toronto, where she will be met by Mr. W. Blome. who is with the Netherlands Immigration Board in Ottawa. A doctor declares the British people are taking 10.000,000 aspirin tablets a day

    Subclinical hyperthyroidism in cats: A spontaneous model of subclinical toxic nodular goiter in humans?

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    Introduction and Objectives: Hyperthyroidism in cats, caused by nodular hyperplasia or adenomas, is clinically and histologically similar to toxic nodular goiter in humans. Subclinical hyperthyroidism in humans is defined as low thyrotropin (TSH) in conjunction with within-reference-range thyroid hormone concentrations, but has not previously been defined in cats. The objective of this study was to test the hypothesis that euthyroid senior cats with low TSH have histological evidence of thyroid nodular hyperplasia and/or adenoma. Design: Thyroid glands removed postmortem from four groups of cats (n = 73) were examined histologically and scored in a blinded fashion. Clinically euthyroid senior (> 7 years) cats were divided into two groups dependent on their TSH concentration-TSH below the limit of quantification (LOQ) of the assay (= 0.03 ng/mL; n = 31; DetectableTSH group)-using archived plasma samples, collected 0-6 months antemortem. Thyroids were also scored for two control groups: Young group (cats < 6 years old; n = 13) and Hyperthyroid group (clinically and biochemically hyperthyroid cats; n = 14). Main outcome: Cats in the UndetectableTSH group had a higher frequency of nodules, a greater percentage of abnormal thyroid tissue, and a higher overall histopathological grade than cats with detectable TSH had. Conclusion: Euthyroid (as defined by total thyroxine) senior cats with low TSH are likely to have histological evidence of nodular thyroid disease, and such cats could be considered to be subclinically hyperthyroid

    Salix diazii M. Idrees & J. M. H. Shaw 1015, nom. nov.

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    Salix × diazii M. Idrees & J.M.H. Shaw, nom. nov. Replaced name:— Salix × longissima T.E.Díaz & J.Andrés (1987: 132), nom. illeg., non S. longissima P.Wessel (1855: 140). Type:— SPAIN. Léon Province: La Martina, 490 m, 29TPH91, 16 June 1985, T.E. Díaz et al. s.n. (holotype, LEB29538!, isotypes LEB29539!, LEB30605!). Etymology:— The specific epithet honours Prof. Dr. Tomás Emilio Díaz González (University of Oviedo, Oviedo, Spain), author of the replaced name, for his tremendous contributions to the taxonomy of the genus Salix. Distribution:— Spain, Léon Province (La Martina).Published as part of Idrees, Muhammad & Shaw, Julian M. H., 2022, A new name for extant Salix × longissima T. E. Díaz & J. Andrés (Salicaceae), pp. 213-214 in Phytotaxa 550 (2) on page 213, DOI: 10.11646/phytotaxa.550.2.11, http://zenodo.org/record/664103

    Contribution of Information and Communication Technology (ICT) in Country’S H-Index

    No full text
    The aim of this study is to examine the effect of Information and Communication Technology (ICT) development on country’s scientific ranking as measured by H-index. Moreover, this study applies ICT development sub-indices including ICT Use, ICT Access and ICT skill to find the distinct effect of these sub-indices on country’s H-index. To this purpose, required data for the panel of 14 Middle East countries over the period 1995 to 2009 is collected. Findings of the current study show that ICT development increases the H-index of the sample countries. The results also indicate that ICT Use and ICT Skill sub-indices positively contribute to higher H-index but the effect of ICT access on country’s H-index is not clear
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