1,720,971 research outputs found
Pairing an Autoencoder and a SF-SOINN for Implementing an Intrusion Detection System
Full text linkIntrusion Detection System are systems aiming to detect intrusions within individual computers or networks. These systems are of fundamental importance nowadays, as the number of attacks on networks is ever increasing. In this paper, a prototype of a new Intrusion Detection System is presented. The key novelty is the architecture of this system, pairing an Autoencoder and a Soft-Forgetting Self-Organizing Incremental Neural Network. A fusing scheme is applied to exploit the classification capabilities of the two approaches. The proposed system, tested in different conditions using the NSL-KDD dataset, has achieved excellent performance in detecting attacks, demonstrating its ability to evolve its knowledge and to recognize attacks never seen before
The new administration approach of the National Health System: implication for internal medicine. The point of view of the internist.
No full textPrimary aldosteronism (Conn's syndrome)
No full textIdiopathic (essential) hypertension is the most common cause of elevated blood pressure (BP) levels in a patient. However, up to 5%–10% of patients with elevated BP are affected by a specific and potentially reversible cause that is known as secondary hypertension. Primary aldosteronism (PA) is the most common form of endocrine hypertension. The diagnostic and therapeutic pathways for PA consist of few important steps: screening tests in high-risk population, identification of PA subtype, and treatment (surgery in case of unilateral adenoma, and if not for surgery, treatment with a mineralcorticoid receptor antagonist). Aldosterone-to-renin ratio is recommended as the initial test to screen for PA; it should be performed after giving adequate wash-out time for several interfering drugs. Confirmatory tests including captopril challenge test and saline infusion test are used if clinical conditions such as spontaneous hypokalemia and increased aldosterone levels are not sufficient to confirm PA. Before surgery, adrenal venous sampling is suggested to ensure accurate lateralization of aldosterone production
Role of Estrogen and Estrogen Receptor in GH-Secreting Adenomas
Full text linkAcromegaly is a rare disease with several systemic complications that may lead to increased overall morbidity and mortality. Despite several available treatments, ranging from transsphenoidal resection of GH-producing adenomas to different medical therapies, complete hormonal control is not achieved in some cases. Some decades ago, estrogens were first used to treat acromegaly, resulting in a significant decrease in IGF1 levels. However, due to the consequent side effects of the high dose utilized, this treatment was later abandoned. The evidence that estrogens are able to blunt GH activity also derives from the evidence that women with GH deficiency taking oral estro-progestins pills need higher doses of GH replacement therapy. In recent years, the role of estrogens and Selective Estrogens Receptor Modulators (SERMs) in acromegaly treatment has been re-evaluated, especially considering poor control of the disease under first- and second-line medical treatment. In this review, we analyze the state of the art concerning the impact of estrogen and SERMs on the GH/IGF1 axis, focusing on molecular pathways and the possible implications for acromegaly treatment
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
- …
