326,382 research outputs found
Chondroitin sulfate. Structure, role and pharmacological activity. Nicola Volpi (Editor)
No full textContents
STRUCTURE Isolation, purification and analysis of chondroitin sulfate proteoglycans Fumiko Matsui and Atsuhiko Oohira Isolation and Purification of Chondroitin Sulfate Luiz-Claudio F. Silva Structure of chondroitin sulfate Fotini N. Lamari and Nikos K. Karamanos Progress in the structural biology of chondroitin sulfate Barbara Mulloy The biosynthesis and catabolism of galactosaminoglycans Vikas Prabhakar and Ram Sasisekharan Biosynthesis of chondroitin sulfate: from the early, precursor discoveries to nowadays, genetic approaches Mauro S.G. Pavao, Ana Christina Vilela-Silva and Paulo A.S. Mourao Advances in the analysis of chondroitin/dermatan sulfate M. Stylianou, I.-E. Triantaphyllidou and D.H. Vynios Chondroitin sulfate lyases - their applications in analysis and glycobiotechnology Emmanuel Petit, Cedric Delattre, Dulce Papy-Garcia and Phillipe Michaud Chondroitin sulfate Lyases: Structure, Activity and Applications in Analysis and the Treatment of Diseases Robert J. Linhardt, Fikri Y Avci, Toshohiko Toida, Yeong Shik Kim and Miroslaw Cygler BIOLOGICAL ROLE OF CHONDROITIN SULFATE Structure, metabolism and tissue roles of chondroitin sulfate proteoglycans Christopher J. Handley, Tom Samiric and Mina Z. Ilic Emergence and structural characteristics of chondroitin sulfates in the animal kingdom Lucia O. Sampaio and Helena B. Nader Role of the sulfation pattern of chondroitin sulfate in its biological activities and the binding of growth factors Chilkunda D. Nandini and Kazuyuki Sugahara Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression A.D. Theocharis, G.N. Tzanakakis and N.K. Karamanos Chondroitin sulfate proteoglycans in tumor progression Yanusz Wegrowski and Francois-Xavier Maquart Chondroitin sulfate proteoglycans in the brain Sachiko Aono and Atsuhiko Oohira Chondroitin/dermatan sulfate in the central nervous system: structures and functions in health and disease Uwe Rauch and Joachim Kappler Chondroitin sulfate proteoglycan and its degradation products in CNS repair Asya Rolls and Michal Schwartz Role of Chondroitin 4-Sulfate in Pregnancy-Associated Malaria D. Channe Gowda PHARMACOLOGICAL ACTIVITIES OF CHONDROITIN SULFATE Immunological activity of chondroitin sulfate Toshihiko Toida, Shinobu Sakai, Hiroshi Akiyama and Robert J. Lindhardt Antioxidant activity of chondroitin sulfate G.M. Campo, A. Avenoso, S. Campo, A.M. Ferlazzo and A. Caltroni Effects of chondroitin sulfate on the cellular metabolism N. Brandl, J. Holzmann, R. Schabus and M. Huettinger In vitro effects of chondroitin sulfate A. Fioravanti, R. Marcolongo and G. Collodel Effect of chondroitin sulfate as nutraceutical in dogs with arthropathies Britta Dobenecker Chondroitin sulfate as a structure modifying agent Daniel Uebelhart, Ruud Knols, Elling D. de Bruin and Gust Verbruggen CLINICAL EFFICACY AND TRIALS Chondroitin sulfate in the management of erosive osteoarthritis of the interphalangeal finger joints Gust Verbruggen Chondroitin sulfate in the management of hip and knee osteoarthritis: an overview Geraldine Bana, Benedicte Jamard, Evelyne Verrouil and Bernard Mazieres Treatment of knee osteoarthritis with oral chondroitin sulfate Daniel Uebelhart, Ruud Knols, Elling D. de Bruin and Gust Verbrugge
Il ‘Flore de vertù et de costume’ secondo il codice S. III. Note lessicali
No full textOsservazioni sul lessico del Flore de vertù (secondo il codice S), opera bolognese di inizio 300
Il Flore de vertù et de costume secondo il codice S. I. Edizione
No full textSi pubblica, per la prima volta in forma integrale, l'edizione del Flore de vertù et de costume, cioè del Fiore di Virtù secondo la lezione del più antico e importante codice della folta tradizione, il ms. Siena, Biblioteca Comunale degli Intronati, I.II.7 (S), realizzato a Bologna agli inizi del XIV secolo. "Scoperto" e valorizzato da Maria Corti nei suoi fondamentali studi sul Fiore, S, oltre a recare un'affidabile versione del fortunato trattatello moralistico, rappresenta un eccezionale documento di prosa bolognese primotrecentesca. La seconda parte del contributo, attesa per il prossimo anno, sarà dedicata allo studio linguistico e lessicale del testimone di Siena
Il ‘Flore de vertù et de costume’ secondo il codice S. II. Studio linguistico
No full textStudio linguistico dle Flore de vertù et de costume, cioè del Fiore di Virtù secondo la lezione del più antico e importante codice della folta tradizione, il ms. Siena, Biblioteca Comunale degli Intronati, I.II.7 (S), realizzato a Bologna agli inizi del XIV secolo, e pubblicato da me su questa rivista, nel numero del 2018. Questo importante documento di prosa bolognese primotrecentesca è stato analizzato nelle sue peculiarità grafiche, fonetiche e morfologiche, con un costante confronto con tutta la documentazione bolognese ed emiliano-romangola, in prosa e in poesia, del Due e del Trecento
DYNAMICS CHANGES IN ENDOTHELIAL EXTRACELLULAR MATRIX INDUCED BY VERY LOW DENSITY LIPOPROTEIN
No full textPreviously we described the vascular extracellular matrix remodeling
induced by normal VLDL at physiological levels
1) Particularly, we described the differences in chondroitin sulfate/
dermatan sulfate proteoglycans (CS/DS-PGs) according to
the endothelial cell phenotypes. 2) The aim of the present study was to analyze the expression
pattern of CS/DS-PGs in the presence of increasing levels of
N-VLDL. Human N-VLDL were isolated by ultracentrifugation
from healthy volunteers. Human umbilical vein endothelial
cells (HlNEC) were obtained and cultured as described by Ulrich-
Merzenic.
3) Then, HlNEC were incubated with 0,75 and 100 mcg/mL of
lipoprotein for 24 h.
Protocols were approved by the Bioethics Committee of the University
of Buenos Aires, Argentina. After treatment, CS/DS-PGs
were characterized through:
1) PG core protein secretion, specifically decorin, biglycan, and
versican analysis by immunoblot;
2) glycosaminoglycans (GAGs) content studied by reverse phase
HPLC;
3) the levels of chondroitin N-acetylgalactosaminyltransferase-2
(ChGn-2) and chondroitin-4-0-sulfotransferase-1 (C4ST-1)
mRNA by RT-PCR.
A significant increase in the protein core of decorin and biglycan
was detected after treatment (0 vs 75 and 0 vs 100 mcg/mL
N-VLDL,p<0.05, n=3), whereas for versican the increase was only
observed at 75 mcg/mL (0 vs 75 mcg/mL N-VLDL,p<O.OOl,n=3).
A significant increase in CS and DS chains was detected at both
levels of N-VLDL (38.5±15.0; 388.0±20.0 and 82.5±50.0 ng/mL; 0,
75 and 100 mcg/mL N-VLDL,p<0.05, n=3), accompanied by an increase
in the sulfation ratio 4S/0S of CS and DS chains (4.88±0.13;
13.97±1.8; 14.53±11.46; 0, 75 y 100 mcg/mL, n=3). No differences
were observed in ChGn-2 and C4ST-1. At physiological levels,
VLDL induced a CS/DS-PG secretion pattern that may contribute
to the atheroprotective properties of this endothelial phenotype;
such characteristics were lost in the presence of higher levels of
the lipoprotein. Our results highlight the importance of CS/DS
PGs as a new target for atherosclerosis treatment,
Bibliografia
1. Oberkersch R, Rasente Y, Barakian B., Yuschak S., Volpi N., Calabrese
G. Extracellular matrix remodeling of endothelial cell was induced by
very low density lipoproteins through NFKB activation. 28° Congresso
Nazionale della Societa ltaliana per 10 Studio dell'Arteriosclerosi. Roma,
Italia. November 23·25, 2014. .
2. Oberkersch R, Rasente Y, Gualco L, Yuschak S, Calabrese G. Very low
density lipoproteins induce differential vascular extracellular remodeling
according to the endothelial phenotype. Angiogenesis and Leukocytes
Atherosclerosis. Geneve, Switzerland. January 30-31, 2014.
3. Ulrich-Merzenich G, Metzner C, Bhonde R, MaIsch G, Schiermeyer
B, Vetter H. Simultaneous isolation of endothelial and smooth muscle
cells from human umbilical artery or vein and their growth response to
low-density lipoproteins
Venice in Volpi
No full textThe article seeks to investigate how Volpi’s voyage to Europe, specially Venice, has had a significant impact on the artist’s pictorial work since this city has chromatic and urban features that can be seen in the artist’s paintings from the 50’s. Este artigo indaga em que medida a viagem realizada por Volpi para a Europa, em particular a Veneza, teve impacto significativo na sua obra pictórica, pois esta cidade possui características cromáticas e urbanísticas que podem ser vistas nas pinturas do artista a partir da década de 1950.
 
The mirror of Volpi : the artists, the critic and São Paulo in the 1940-50's
No full textOrientador: Heloísa André PontesDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciências HumanasResumo: O pintor Alfredo Volpi (1896 ¿ 1999) nasceu na Itália e se formou em São Paulo no contato com artistas imigrantes. Ele é considerado, por diversos estudiosos, um dos mais importantes pintores brasileiros. Vários críticos dedicaram-se às suas obras, quase sempre recorrendo a uma narrativa a respeito de sua biografia e personalidade. Essa forma de analisar Volpi, embora exista até hoje, remonta a Mário de Andrade (1893 ¿1945) e Mário Pedrosa (1900 ¿1981). Mais precisamente, ao período entre 1944 e 1957, quando, em São Paulo e no Rio de Janeiro, aconteceram importantes exposições do artista. Respectivamente, a primeira mostra individual e a primeira retrospectiva. É nesse período que Volpi é abrasileirado e ascende ao nosso panteão. Tomei essa personalidade pública como foco de análise, o que significa que me debrucei sobre a relação entre os críticos de arte e o próprio artista no período em que Volpi atuava. Há um diálogo entre as expectativas dos primeiros e a produção do segundo. Nessa conversa, mais ou menos tensa, a noção de pessoa, tema clássico da Antropologia, é mobilizada para embaralhar a posição do sujeito e sua obra. Nessa dissertação, ambos, pintor e pintura, criam-se simultaneamente e dividem a prerrogativa heurística para apreensão do processo. É, ao abrasileirar Volpi, que os críticos conseguem renovar a história da arte e relativizar os cânones que já haviam se estabelecido. Ou seja, é ao instituir uma personalidade específica, um proletário com pendor artesanal e isolado no subúrbio de São Paulo, que os críticos e o artista fizeram a história da arte nacional se desenrolar. Esse processo, analisado por outro ângulo, revelou a importância das redes de artistas imigrantes em São Paulo e a centralidade de instituições, como os colégios técnicos, que, na capital paulista, possibilitaram o surgimento de uma iconografia brasileira feita por imigrantes e filhos de imigrantes. O artista, por meio de sua obra, e a crítica de arte são espelhados um no outro. Ambos revelam uma negociação ao redor das ideias de nacionalismo e modernidade que situa e consagra Alfredo VolpiAbstract: The painter Alfredo Volpi (1896-1999) was born in Italy and raised in Sao Paulo beside immigrant artists. He is also considered, by many scholars, one of the most important Brazilian painters. Several critics analyzed his work, almost always resorting to a narrative regarding his biography and personality. This way of analyzing Volpi, although still present nowadays, date back to Mario de Andrade (1893-1945) and Mario Pedrosa (1900-1981). More specifically, to the period between 1944 e 1957, when, in Sao Paulo and Rio de Janeiro, important exposées of Volpi¿s work took place. Respectively, his first individual display and the first retrospective. It is in this precise period that Volpi pointed Brazilian and ascend to our pantheon. I took this public personality as analytical focus, which means that I leaned over the relation between art critics and the artist himself, as well as the dialogue between their expectations and his artistic production. In this relatively tense conversation, the notion of personhood, a classical anthropological topic, is deployed to shuffle the subject¿s position and his work. In this dissertation, both painter and painting create themselves simultaneously and divide the heuristic prerogative for that process¿ apprehension. In making Volpi Brazilian, the critics manage to renew the history of art and render relative established canons. Put it differently, in instituting a specific personality ¿ an isolated proletarian man living in the Sao Paulo¿s suburbs with artistic penchant ¿ the artist and his critics uncoiled the national history of art. That process, viewed by another angle, revealed the importance of immigrant relation nets and also the centrality of institutions, such as the technical schools that, in sao Paulo, made possible the outcome of an Brazilian iconography created by immigrants and their children. The artist, through his work, and the art critic are mirrored in one another. They both reveal a negotiation surrounding ideas about nationalism and modernity that locate and consecrate Alfredo VolpiMestradoAntropologia SocialMestre em Antropologia Social2013/09275-2FAPES
Noise assessment in the diagnosis of rolling element bearings
No full textIn this paper we perform a noise analysis to assess the degree of robustness to noise of a neural classifier aimed at performing multi-class diagnosis of rolling element bearings. We work on vibration signals collected by means of an accelerometer and we consider six levels of noise, each of which characterized by a different signal-to-noise ratio ranging from 40.55 db to 9.59 db. We classify the noisy signals by means of a neural classifier initially trained on signals without noise, then we repeat the training process with signals affected by increasing levels of noise. We show that adding noisy signals to the training set we manage to significantly increase the classification accuracy
Fisiocrazia e riforma dell'agricoltura: il caso di Giovanni Neri, funzionario dei Lorena
No full textExpression and construction: Alfredo Volpi, João Cabral de Melo Neto and modern art in Brazil
No full textEsta tese interpreta, com foco nas obras de Alfredo Volpi e João Cabral de Melo Neto, o processo de modernização e rotinização da arte moderna no Brasil, Os poemas de Cabral e as pinturas de Volpi podem ser analisados como produtos de um novo contexto \"moderno\" para a arte no Brasil da década de 1950 e, ao mesmo tempo, produtores deste mesmo contexto, já que ambos estabelecem nexos importantes para a sua justificativa social, teórica e artística. A pesquisa teve como objetivo contribuir, por meio, principalmente, da leitura crítica de poemas e pinturas, para a reflexão sobre os rumos e contradições da arte moderna no Brasil.This thesis aims to investigate the process of modernization and routinization of modern art in Brazil, focusing on the works of Alfredo Volpi and João Cabral de Melo Neto. Cabral\'s poems and Volpi\'s paintings are seen as products of a new \"modern\" context for the art in Brazil in the 1950s and, at the same time, as producers of this same context, since both establish important nexus for its social, theoretical and artistic justification. This research aims to contribute, mainly by close critical readings of poems and paintings, to the reflection on the development and contradictions of modern art in Brazil
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