28 research outputs found
Cognitive Impairment in Heart Failure : Cardiovascular correlates of the cognitive profile in relation to brain magnetic resonance imaging abnormalities in patients with heart failure
Scheltens, P. [Promotor]Weinstein, H. [Copromotor
Judicial Adjudication in Problems of School Attendance
Education, like every other important task of society, would surely be greatly handicapped without the benevolent intervention of the courts in our country. Adjudication of the many problems -- in which education through practical application of theory becomes involved -- has been left with our judicial system. The intervention of the judiciary has been received by some in an unwelcome manner, but every wise thinking .American deems judicial adjudication not only desirable but absolutely essential to the success of our public school system.
It has been estimated that approximately one million six hundred thousand decisions of appellate courts since 1658 in this country have been put at the disposal of attorneys and students of the law. Only when one becomes entangled in some part of that vast maze of cases and returns therefrom with a classification of the law grouped around a certain topic can one experience the particular satisfaction which has been that of the author of this thesis. Work on this thesis has been made an intensely interesting and satisfactory occupation because of its very nature
Towards a coupled morphodynamic model of the nearshore zone and the beach at the Sand Engine: Combining waves, tide, morphodynamics and aeolian sediment transport into a process-based model
Morphodynamic models are widespread in coastal engineering practice and indispensable to predict the effectiveness of (large-scale) sandy interventions. These models enable quantification of the effects on enhanced safety against flooding and on environmental impact over time, based on physical processes such as hydrodynamics and sediment transport. The Sand Engine is a mega-scale nourishment pilot along the Dutch coast with a substantial sub-aerial surface and significant aeolian sediment transport, which highlights the need to integrate aeolian sediment transport and dry beach changes in current morphodynamic models. An explicit objective of the Sand Engine emphasizes this need: its dune area should increase by natural processes in the coming years, a process linked to aeolian sediment transport. In order to accurately model the morphological evolution of the Sand Engine, a model incorporating both morphodynamics and aeolian sediment transport is preferable. However, morphodynamics and aeolian sediment transport interact and the dynamics of the bathymetry and the water line cause the physical interface between sub-aerial and sub-aqueous processes to be highly variable both in space and time, making it complex to model the (lower) beach and the nearshore zone. Current morphodynamicmodels such as Delft3D FlexibleMesh (FM) only take into account hydrodynamic forces as drivers for sediment transport and do not resolve bed changes on the dry beach. Vice versa aeolian sediment transport models as AeoLiS do not include hydrodynamics and subaquaeous sediment transport. Recent developments in model couplings allow implementing the interaction between morphodynamics and aeolian sediment transport.Civil Engineering and GeosciencesHydraulic Engineerin
Multibody Dynamics Modeling of Flexible Aircraft Flight Dynamics
Because of the focus on weight minimization, aircraft are becoming more and more flexible. Therefore, the frequency separation between flight mechanics motion and structural vibration decreases. This calls for a flight mechanics model that includes aeroelasticity. The development of such a model was the subject of the current research. This model can be used for gust and maneuver load prediction in the preliminary design phase. With accurate load prediction, structural integrity can be ensured and unstable flight conditions can be avoided. Moreover, the model may be used to design active load alleviation systems to increase passenger comfort, reduce fatigue, and decrease loads on the wing structure. A modal structural model and a quasi-steady aerodynamics model are integrated in a partitioned manner to form an aeroelastic wing model. This aeroelastic wing model is implemented in a multibody dynamics environment, in order to model flight dynamics and the effect of aeroelasticity thereon. An A320-like aircraft was analyzed in the current research. The effect of aeroelasticity on flight mechanics was investigated. Inclusion of flexibility substantially affected the trim control variables, but had an almost negligible effect on the flight mechanics modes and stability derivatives. When flexibility increases, these parameters are affected. Aeroelasticity has a non-negligible effect on the (peak) wing loads after maneuvers or disturbances. Especially for maneuvers or disturbances that increase lift, and therefore wing deformation, the peak loads are affected. Moreover, wing loads are particularly affected by disturbances that have a direct effect on the wing, such as aileron deflection. The objective of the current research was to improve on an existing aeroelastic flight mechanics model, based on the lumped-parameter approach. The modal model created in the current research proved to have a computational effort that is several times lower than the lumped-parameter model. In addition, the accuracy of the modal model can be increased beyond that of the lumped-parameter model at only a small additional computational cost. Because of the reduced computational cost, and the potentially increased accuracy, the modal model performs better than the lumped-parameter model. Due to the qualitative nature of these conclusions, it is probable that they can be extended to other conventional, low aspect-ratio aircraft in the subsonic flight regime. Definitive, quantitative conclusions could not be formulated, because of the absence of complete validation data.Flight Performance and PropulsionFlight Performance and PropulsionAerospace Engineerin
Ensemble: An exploration of reciprocity and the act of giving to reinvent the elderly home
The studio ‘Designing for Care – towards an Inclusive Living Environment’ engages with the living environment of elderly that are in need of care. While our society has to cope with a growing amount of elderly, the existing care buildings often do not meet the needs and wishes of our current elderly who want to be more independent. Though they might need help at some point in time, they want to be self-governing and stay part of society. To be able to house the future generations, things have to change. The goal is to design a place where elderly with and without care can live together with others, which takes into account their wishes and needs and gives them something to look forward to. A place that does not exclude elderly from society, but makes them part of it again. One that stimulates them, encourages them to participate and contribute, enjoy and laugh. In which people look after each other and take care of each other. A social net. A place they can transfer their knowledge gathered throughout life, tell their stories and one in which they can in turn learn from others. A community based on reciprocity.Designing for CareArchitecture, Urbanism and Building Sciences | Dwellin
Facing epistemic uncertainty: characteristics, possibilities, and limitations of a discursive contextualist approach to philosophy of education
Increasing doubts over the narratives that traditionally served to legitimize the tasks and possibilities of societal institutions - such as science - have also called into question the significance of philosophy to educational thinking. Related debates largely concern epistemological issues, i.e. issues regarding the nature and status of (scientific) knowledge. This dissertation takes as its starting point the nowadays hardly controversial idea that all knowledge is to a certain extent ‘uncertain’. The questions addressed are how this ‘epistemic uncertainty’may be intelligibly understood, and what consequences can be drawn from such an understanding for the tasks and possibilities of philosophy of education as an academic discipline. In response to antifoundationalist as well as fallibilist authors, the author develops a discursive contextualist approach to epistemology that gives way to a philosophy of education that has both critical-reflective and theoretical-constructive potential, as is illustrated in relation to the educational issue of dealing with ‘students at risk’
How tides and waves enhance aeolian sediment transport at the sand motor mega-nourishment
Expanding knowledge concerning the close entanglement between subtidal and subaerial processes in coastal environments initiated the development of the open-source Windsurf modeling framework that enables us to simulatemulti-fraction sediment transport due to subtidal and subaerial processes simultaneously. The Windsurf framework couples separate model cores for subtidal morphodynamics related to waves and currents and storms and aeoliansediment transport. The Windsurf framework bridges three gaps in our ability to model long-term coastal morphodynamics: differences in time scales, land/water boundary and differences in meshes.The Windsurf framework is applied to the Sand Motor mega-nourishment. The Sand Motor is virtually permanentlyexposed to tides, waves and wind and is consequently highly dynamic. In order to understand the complexmorphological behavior of the Sand Motor, it is vital to take both subtidal and subaerial processes into account. The ultimate aim of this study is to identify governing processes in aeolian sediment transport estimates in coastal environments and improve the accuracy of long-term coastal morphodynamic modeling. At the Sand Motor beach armoring occurs on the dry beach. In contrast to the dry beach, no armor layer can be established in the intertidal zone due to periodic flooding. Consequently, during low tide non-armored intertidal beaches are susceptible for wind erosion and, although moist, may provide a larger aeolian sediment supply than the vast dry beach areas. Hence, subtidal processes significantly influence the subaerial morphology and both need to be accounted for to understand the long-term aeolian morphodynamic behavior of the Sand Motor.Coastal Engineerin
Coastal protection Malecón seawall: A study to develop a sea defence solution that prevents unacceptable flooding and damage to the 'Malecón Tradicional' in Havana, Cuba
This report presents a study of the Malecón Tradicional in front of ‘Centro de Havana’ and ‘Havana Vieja’ in the city Havana, Cuba. The objective is to develop a sea defence solution that prevents unacceptable flooding of the hinterland and damage of the Malecón seawall. Implementing the recommended solutions reduces the overtopping sufficiently. Along the entire study area, it is recommended to raise the seawall and to construct a revetment. It was concluded that a curved wall is only useful in combination with a revetment for a small part of the seawall. Both the top part and the seaside face of the Malecón seawall need a structural fortification in order to withstand the design conditions. It is recommended to partly remove the top of the current wall and replace it with a new wall, which is extended in seaward direction. Both for the design storm and for the ultimate limit state, the proposed solution satisfies the strength requirements.Hydraulic EngineeringCivil Engineering and Geoscience
Profile of cognitive impairment in chronic heart failure
Item does not contain fulltextOBJECTIVES: To determine the frequency and pattern of cognitive dysfunction in outpatients with chronic congestive heart failure (CHF) and to identify the corresponding demographic and clinical correlates.
DESIGN: Case-control study.
SETTING: Outpatient clinic in a community hospital.
PARTICIPANTS: Sixty-two outpatients with CHF, 53 controls diagnosed with cardiovascular disease uncomplicated by CHF (cardiac controls), and 42 healthy controls were investigated.
MEASUREMENTS: Neuropsychological assessment included tests of mental speed, executive function, memory, language, and visuospatial function. Composite z-scores for five cognitive domains and mean z-score for overall cognitive performance were computed. The cutoff score to indicate cognitive impairment was defined as the overall healthy participants' cognitive z-score minus 2 standard deviations. Independent demographic and clinical predictors of cognitive impairment were identified using linear regression analysis.
RESULTS: Patients with CHF showed a pattern of general cognitive impairment, including impairment of executive function, memory, language, mental speed, and attention. Twenty-five percent (P=.04) of patients with CHF were classified as cognitively impaired, compared with 15% of the cardiac controls and 4% of the healthy controls. Independent predictors of cognitive impairment in patients with CHF were estimated intelligence, New York Heart Association class, and presence of the apolipoprotein (Apo)E ɛ4 allele.
CONCLUSION: Cognitive dysfunction is relatively common in patients with CHF, with deficits being most prominent in the domains of executive function, memory, language, and mental speed. Disease severity and ApoE genotype are likely to be important determinants for cognitive impairment in patients with chronic CHF.7 p
