1,720,962 research outputs found
Analysis of the Skew Deviation to Evaluate the Period of Onset of a Canalolithiasis After Macular Damage
Get PDFBenign paroxysmal positional vertigo (BPPV) is the most common peripheral vestibular end-organ disease, and it is one of the first causes of access to the emergency room. The moment of migration of the otoconial debris in a semicircular canal does not necessarily coincide with the moment of detachment of the debris themselves. Consequently, the paroxysmal positional vertigo could arise with a variable delay with respect to the mechanical damage suffered by the macula. The aim of this work is to try to identify objective criteria to establish whether a canalolithiasis is synchronous or diachronic to the damage. The analysis of skew deviation in the context of ocular tilt reaction in patients with canalolithiasis could provide useful information to understand if macular damage occurred at the origin of the disease and when the damage may have occurred. In this study, 38 patients with BPPV were analyzed based on the type of skew deviation that was presented. We found that if the eye on the side of the canalolithiasis is hypotropic the damage of the utriculus is likely recent (last 10 days), if it is hypertropic the damage is not recent (20 days before) and finally if the eyes are at the same height it could be an utricular damage in compensation (occurring the last 10-20 days) or a secondary labyrinth canalolithiasis, without associated utricular damage. Our results show that the evaluation of skew deviation in patients suffering from BPPV could be useful to evaluate: (a) if a positional paroxysmal nystagmus can be related to an previous relevant injury event (for example a head injury that occurred days before the crisis); (b) if it is a BPPV of recent onset or a re-entry of the debris into the canal
Nasopharyngeal sarcoidosis: case reports and literature review
Get PDF: Sarcoidosis is a multisystemic inflammatory chronic disease characterized by the presence of noncaseating granulomas most frequently in lungs and in intrathoracic lymph nodes. The nasopharyngeal form is unusual and noncommon in the ENT practice. Background and objectives: In order to establish a correct knowledge about this rare disease, we report two different cases of nasopharyngeal sarcoidosis moreover all the available literature is reviewed. Materials and methods: A systematic literature review was made through PubMed databases, according to the PRISMA guidelines (1), combining the following key words: Nasopharyngeal, Rhinopharynx, Sarcoidosis, in publications between 1951 and 2020. In addition, we reported our personal experience on the disease by describing two clinical cases that occurred at our clinic in November 2018 and June 2019. Results: 16 articles reported 27 cases of nasopharyngeal sarcoidosis. The number of males was 13 (48,2%) and the number of females was 14 (51,8%) with a mean age at the diagnosis of 35,28 ± 13.05 years old (range 5 - 64). In 16 (59,3%) cases nasopharyngeal sarcoidosis was associated with lungs and/or intrathoracic lymph nodes involvement; nasal obstruction was the most frequently reported symptom (51,8% of subjects). Conclusions: Nasopharyngeal sarcoidosis can mimic several disorders of the upper airway respiratory tract and it must therefore be considered in the differential diagnosis. A biopsy of nonspecific lesions in the nasopharynx is advisable to permit several early diagnosis of upper airway respiratory tract disorders including sarcoidosis
Human papillomavirus-related head and neck adenosquamous carcinoma: A systematic review and individual patient data meta-analysis
No full textThis work examined published papers of patients affected by human papillomavirus-related head and neck adenosquamous carcinoma. Demographic data, tumor site and sub-site, TNM stage, HPV status (positive VS negative) and the technique used for its identification, the treatments performed, follow-up time and patient's status at follow-up were assessed. Three papers including 26 patients resulted eligible for the study. The incidence of HPV-positive Adenosquamous Carcinomas located in the oropharynx was significantly higher than HPV-negative tumors (p = 0.01), especially if the origin of primary unknown tumors was considered within this anatomical site (p < 0.0001). HPV-positive Adenosquamous Carcinomas had a higher incidence of small primary tumor (Tx + T1) (p = 0.03) and bulky cervical lymph node metastasis (N2) at presentation (p = 0.02). HPV-positive and HPV-negative tumors had similar OS and DFS. Head & Neck HPV-positive Adenosquamous Carcinoma seems to act like HPV-positive conventional Squamous Cell Carcinoma, thus we suggest to determine the HPV status of Adenosquamous Carcinoma during the diagnostic phase
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
VERSATILITA ED ATTUALITA DEL LEMBO DI MUSCOLO TEMPORALE NELLA RICOSTRUZIONE DELLA MESOSTRUTTURA
No full textBackground. Il lembo di muscolo temporale è un lembo muscolare peduncolato utilizzabile in casi selezionati in grado di garantire una soddisfacente ricostruzione estetica e funzionale. Si sono valutati gli outcomes estetici e funzionali dopo ricostruzione della mesostruttura con lembo di muscolo temporale. Materiali e metodi. In questo lavoro sono stati analizzati retrospettivamente 29 pazienti, età media anni 64. con tumori maligni della mesostruttura, sottoposti dal 1 gennaio 2013 al 31 luglio 2019 presso le U.O ORL Universitaria e Audiologia e Foniatria ad interventi di maxillectomia e ricostruzione con lembo di muscolo temporale. Risultati. Dei 29 soggetti, 22 sono stati analizzati e hanno completato la valutazione clinica-osservazionale e firmato il consenso informato. Tutti i lembi sono stati eseguiti con successo chirurgico, 4 lembi revisionati in anestesia locale. Nessun decesso intra, peri e post operatorio immediato, nessuna infezione e/o necrosi del lembo. Alla visita di follow-up (25 ± 19 mesi), 5 soggetti (22.7%) avevano una recidiva locale e/o a distanza e 17 (77.3%) nessuna evidenza di malattia. La media del punteggio dell’outcome estetico è stata buona ed il punteggio relativo al questionario Version of Voice Handicap Index 30 sulla fonazione ha evidenziato difetti vocali minori con un risultato nel complesso soddisfacente. Il P-score dell’esame fibroscopico della deglutizione (FEES) (4.64±0.95) ha evidenziato assenza di segni di disfagia. Conclusioni. Il lembo di muscolo temporale è una buona opzione chirurgica per la ricostruzione dei difetti della mesostruttura, adatto particolarmente alla popolazione anziana o con comorbidità per cui è preferibile ridurre per quanto possibile i tempi operatori.
Background. The temporal muscle flap is a pedunculated muscle flap that can be used in selected cases able to guarantee a satisfactory aesthetic and functional reconstruction. Aesthetic and functional outcomes were evaluated after reconstruction of the mesostructure with temporal muscle flap. Materials and methods. In this work, 29 subjects, average age 64 years, were retrospectively analyzed with malignant tumors of the mesostructure, from 1 January 2013 to 31 July 2019 at the Otolaryngology and Head and Neck Surgery Department Of University of Pisa, subjected to maxillectomy and reconstruction with temporal muscle flap. Results. Of the 29 subjects, 22 were analyzed and completed the clinical-observational evaluation and signed informed consent. All flaps were performed with surgical success, 4 flaps revised under local anesthesia. No immediate intra, peri and postoperative deaths, no infection and/or necrosis of the flap. At the follow-up visit (25 ± 19 months), 5 subjects (22.7%) had local and/or distant recurrence and 17 (77.3%) no evidence of disease. The average of the aesthetic outcome score was good and the score relating to the Version of Voice Handicap Index 30 questionnaire on phonation showed minor vocal defects with an overall satisfactory result. The P-score of the fibroscopic examination of swallowing (FEES) (4.64 ± 0.95) showed no signs of dysphagia. Conclusions. The temporal muscle flap is a good surgical option for the reconstruction of defects of the mesostructure, particularly suitable for the elderly population or with comorbidities for which it is preferable to reduce the operating times as much as possible
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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