1,042 research outputs found

    Shared Decision Making in women testing for a BRCA 1/2 mutation.

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    Contains fulltext : 19591_shardemai.pdf (Publisher’s version ) (Open Access)Women with a BRCA1/2 mutation have a high genetic risk of developing breast and ovarian cancer. They face the difficult choice between screening and prophylactic surgery for the breasts and ovaries. We have developed a shared decision making program to prepare these women for decision making. The shared decision making program consisted of two decision aids. The decision aids have been developed as adjuncts to standard genetic counselling and were evaluated in a randomized trial. The study included both women affected and unaffected with cancer testing for a BRCA1/2 mutation. The first decision aid consisted of a brochure and video providing information on screening and prophylactic surgery and their consequences. It was provided either before or after the DNA-test result. This decision aid had no impact on well-being neither on decision related outcomes. Beneficial effects were found on information related outcomes. These effects occurred irrespective whether the decision aid was presented before or after the DNA-test result. No interaction effect was found between the DA and the personal history of cancer. The second decision aid consisted of two value assessment sessions, using the time trade-off method, followed by individualized treatment information based on (quality adjusted) life expectancy derived form a decision model. This decision aid only had an effect on the long term (9 months after the test result). Women reported less intrusive thoughts about cancer, a better general health, and tended to be less depressed. Furthermore, the SDMI strengthened treatment preferences and increased the feeling of having weighed the pros and cons. A differential impact was found in women affected with cancer versus unaffected women. Unaffected women benefited from this decision aid, while affected women tended to experience detrimental effects. The effects of the two decision aids are complementary. Thus, preferably, the complete support package should be offered.KUN Katholieke Universiteit Nijmegen, 21 februari 2005Promotor : Daal, W.A.J. van Co-promotores : Stalmeier, P.F.M., Verhoef, C.G.141 p

    Apophatic Elements in the Theory and Practice of Psychoanalysis: Pseudo-Dionysius and C.G. Jung

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    This thesis identifies apophatic elements in the theory and practice of psychoanalysis through an examination of Pseudo-Dionysius and C.G. Jung. Pseudo-Dionysius brought together Greek and Biblical currents of negative theology and the via negativa. The apophatic concepts and metaphors which appear in the work of Pseudo-Dionysius are identified. The psychology of Jung can be read as a continuation and extension of the apophatic tradition. The presence of neoplatonic themes in Jung’s work is discussed, as well as his references to Pseudo-Dionysius. There is a thorough examination of Jung’s discussion of opposites, including his reception of Nicholas of Cusa’s concept of the coincidence of opposites. The role of the transcendent function in Jung’s psychology is reviewed. The work of contemporary scholars of religion, philosophers and Jungian theorists are compared to Jung’s using the lens of apophasis. There is an exploration of ways in which motifs in Pseudo-Dionysius’ Ecclesiatical Hierarchy resonate with contemporary psychoanalytic psychotherapy. This study demonstrates that apophatic motifs saturate Jung’s work. It provides a platform for research into apophasis in the wider field of psychoanalysis

    C.G. Jung et les théologiens

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    Hélène Kiener. C.G. Jung and the theologians. (C.G. Jung et les théologiens.) This article is by one of the students of the psychologist C.G. Jung. She practised as a Jungian psychoanalyst in Strasbourg from 1946 to 1970. She deals here with the theological dimension, mostly implicit, of Jung's thouth, which is generally overlooked by theology. The author shows how the major theologians, who are the exception to the general rule, make room for Jungian anthropology, and she calls for a more open attitude in theology, because of the light thrown by Jung's thought on many theological statements.L'article qu'on lira est d'une élève du psychologue des profondeurs C. G. Jung. Elle a pratiqué elle-même l'analyse jungienne à Strasbourg de 1946 à 1970. La question traitée porte sur la dimension théologique généralement implicite de la pensée de Jung, assez négligée d'une manière générale par la théologie. L'auteur expose la manière dont les principaux théologiens, qui font exception , font droit à l'anthropologie jungienne, et en appelle à une ouverture plus grande de la théologie en raison de la lumière que la pensée de Jung jette sur bien des affirmations théologiques.Kiener Hélène. C.G. Jung et les théologiens. In: Revue d'histoire et de philosophie religieuses, 60e année n°3, Juillet-septembre 1980. pp. 293-311

    Letter from C.G. Ames to Thomas Lamb Eliot

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    https://rdc.reed.edu/v1/resources/859b5c69-cfa2-40cf-b99a-a75fadd02e8f/thumb/128.jpgIt is possible that the author is Reverend Charles Gordon Ames, who was also a Unitarian minister and was in Germantown, Pennsylvania during this time

    An Investigation of Transitional Phenomena from Laminar to Turbulent Natural Convection using Compressible Direct Numerical Simulation

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    The transitional phenomena from laminar to turbulent natural convection and the development process inside the channel are investigated using compressible direct numerical simulation (DNS). Numerical method of Roe scheme with preconditioning and dual time stepping are used for addressing natural convection flows with large temperature differences, which are low speed but the densities are variable. The results are qualitatively well consistent with the experimental data [1] and the transition point can be accurately captured. In addition, the development process respected to time can be clearly identified for four stages, which are laminar, unstable process, reliminarization and turbulence. After reaching the quasi-steady state, it can be observed that the laminar, transition and turbulence coexist in the same flow filed. Most important of all, the transitional phenomena are naturally induced by the effects of interactions between the buoyancy and shear stress without adding any fluctuations at inlet. It means that the numerical scheme and physical model adopted in this study has the potential to be a universal case for estimating the accuracy of turbulence model because the characteristics of parameters-free and independence from inlet condition

    Poiesis and Obstruction in Art Practice

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    This PhD thesis examines the concept of poiesis, that is ‘calling into existence that which was not there before’, in the context of obstruction in studio practice. It poses the question ‘Is there a methodology that engages with obstruction which in turn calls new work’? In this thesis, the concept of poiesis emerging from the late Dr. Murray Cox’s ‘Aeolian Mode’, is analyzed alongside a concept of praxis, (a philosophical companion to poiesis), familiar to artistic practice. This thesis describes the orientation of the original idea, The Aeolian Mode, clinically developed by Dr. Murray Cox in Broadmoor Psychiatric Hospital. This PhD seeks to identify if there are similar ‘tenets of approach’ held within the methodology of ‘The Aeolian Mode’, that would be useful or are identifiable in artistic studio practice. This thesis draws on the work of the philosopher, Professor Richard Kearney, specifically Kearney’s ideas on the necessity of ‘the other’ for ‘radical possibility’ to occur. It maps a context of both Freudian and Jungian interpretations of art practice, identifying how these ideas have shaped the way art is seen today. Furthermore, it challenges the Freudian idea of ‘pathography’ and favours a Jungian approach of ‘individuation’ in the understanding of creative processes. It develops a ‘methodology of the conversation’, interviewing students, established artists, tutors about their approaches to obstruction/poiesis in art practice. Additionally, it examines my own obstruction to painting and identifies the methodology that released me from this obstruction. Conducting these interviews on art practice has enabled me to confirm my initial concerns about Freudian ‘pathography’ whilst validating the possibility of the Jungian concept of ‘individuation’ being of use to art practice. Finally, this PhD discusses the implications for further study and research, which have emerged during the ‘methodology of the conversation’ and the task of dissolving my obstruction to painting

    Microbial aspects of anaerobic methane oxidation with sulfate as electron acceptor

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    Anaerobic oxidation of methane (AOM) is an important methane sink in the ocean but the microbes responsible for AOM are as yet resilient to cultivation. It was shown that AOM was coupled to sulfate reduction (SR) and this gave rise to current research which aims to develop a biotechnological process in which methane is used an electron donor for SR. This thesis describes the microbial analysis of an enrichment capable of high rate AOM (286 µmol.gdry weight-1.day-1) coupled to SR using a novel submerged membrane bioreactor system. Initially AOM rates were extremely low (0.004 mmol L-1 d-1), but AOM and SR increased exponential over the course of 884 days to 0.60 mmol L-1 d-1. The responsible organisms doubled every 3.8 months. By constructing a clone library with subsequent sequencing and fluorescent in situ hybridization (FISH), we showed that the responsible methanotrophs belong to the ANME-2a subgroup of anaerobic methanotrophic archaea, and that sulfate reduction is most likely performed by sulfate reducing bacteria commonly found in association with other ANME related archaea in marine sediments. Another relevant portion of the bacterial sequences can be clustered within the order of Flavobacteriales but their role remains to be elucidated. FISH analyses showed that the ANME-2a cells occur as single cells without close contact to the bacterial syntrophic partner. Incubation with 13C labeled methane showed substantial incorporation of 13C label in the bacterial C16 fatty acids (bacterial; 20, 44 and 49%) and in archaeal lipids, archaeol and hydroxyl-archaeol (21 and 20%, respectively). This confirms that both archaea and bacteria are responsible for the anaerobic methane oxidation in a bioreactor enrichment inoculated with Eckernförde bay sediment. To unravel the pathway of this syntrophic conversion, the effect of possible intermediates on AOM and SR was assessed. To investigate which kind of waste and process streams can be treated by the methanotrophic sulfate-reducing enrichment, the effect of environmental conditions and different substrates was assessed. The optimum pH, salinity and temperature for SR with methane by the enrichment were 7.5, 30‰ and 20°C, respectively. The biomass had a good affinity for sulfate (Km 75 KPa) and AOM was completely inhibited at 2.4 (±0.1) mM sulfide. The enrichment utilized sulfate, thiosulfate, sulfite and elemental sulfur as alternative electron acceptors for methane oxidation and formate, acetate and hydrogen as alternative electron donors for sulfate reduction. As a co-substrate for methane oxidation only methanol stimulated the conversion of 13C labeled CH4 to 13CO2 in batch incubations of Eckernförde bay sediment, other possible co-substrates had a negative effect on the AOM rate. The research described in this thesis shows the possibility of enriching slow growing methane oxidizing communities but also shows the difficulties in applying this process for a biotechnological purpose because of the extreme slow doubling times and the lack of understanding of the metabolic routes used by these organisms. <br/

    An Efficient Probabilistic Algorithm to Detect Periodic Patterns in Spatio-Temporal Datasets

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    Author Contributions: Conceptualization, C.G.-S.; methodology, C.G.-S.; software, C.G.-S.; validation, C.G.-S., P.G. and M.A.P.; formal analysis, C.G.-S.; investigation, C.G.-S., P.G. and M.A.P.; data curation, C.G.-S.; writing—original draft preparation, C.G.-S., P.G. and M.A.P.; writing—review and editing, M.A.P.; funding acquisition, C.G.-S. and M.A.P. All authors have read and agreed to the published version of the manuscript.Peer reviewe

    C.G. Jung and Indian religious tradition

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    Reikšmingą vaidmenį, tyrinėjant didžiųjų Rytų tradicijų filosofines, psichologines koncepcijas, suvaidino žymiausias XX amžiaus šveicarų psichiatras ir kultūrologas Carlas Gustavas Jungas (1875-1961), pagarsėjęs kolektyvinės pasąmonės ir universalių archetipų teorijomis. Tyrinėdamas žmogaus sąmonės gelmes, Jungas plačiai domėjosi įvairių senųjų civilizacijų ir pirmykščių tautų mitiniais vaizdiniais, simboliais, dvasinio gyvenimo principais. Jungas buvo vienas pirmųjų Vakarų mokslininkų, itin palankiai įvertinusių Indijos religinės tradicijos patyrimą. Plačiai yra žinomi jo psichologiniai komentarai pirmiesiems įvairiems klasikinių Rytų tekstų vertimams: „Commentary on The Secret of the Golden Flower“ (1929), „Psyhological Commentary on The Tibetan Book of the Great Liberation“ (1939), „Foreword to Suzuki’s Introduction to Zen Buddhism“ (1939), „Foreword to I Ching“ (1950), „Psyhological Commentary on The Tibetan Book of the Dead“ (1935). Šie komentarai buvo bene pirmasis bandymas, naudojantis Vakarų psichologijos kategorijomis, akyliau pažvelgti į Rytų dvasinį paveldą, išryškinant Azijos regiono specifinį mąstymą, gyvenseną, ir neabejotinai daug prisidėjo prie šio paveldo receptavimo Vakaruose, gvildenant kultūrinės Rytų ir Vakarų sąveikos problematiką. Religijų tyrinėtojams jo gausūs kūriniai apie archetipinę simboliką yra tapę pagrindiniu interpretacijų šaltiniu. Reikšminiai žodžiai: C. G. Jungas; Analitinė psichologija; Indų religijos; Krikščionybė; Joga; C.G. Jung; Analytical psychology; Indian religious tradition; Christianity; YogaAttention is drawn to the fact that C.G. Jung’s psychological and cross-cultural writings about India reveal a mixture of reverent praise for, and irreverent condemnation of, traditional spiritual Hindu value. In this article utilising the main works of Jung on this subject, the author analyses the questions: Why was he so ambivalent towards the Hindu religious tradition? Why he insisted on sharply distinguishing between European individuation process of analytical psychology and any Hindu or Buddhist experience? Did he possess a sufficiently detailed knowledge of the history of the Hindu and Buddhist religious tradition to comprehend its incredible complexity? Jung’s aim was to develop a cross-cultural comparative psychology of inner experience. He considered the introverted religions of the East as a great challenge to the Western psychology as therapy. He openly admired the Eastern yoga principle of inclusiveness and balance between the opposing aspects of psychic function (dvandva). Being himself the empirical psychologist, he felt very close to the Eastern mystical traditions, but always remained true to his own "reality of the psyche". He concludes that whereas yoga practice constitutes the royal road to the unconsciousness for the Indian, the European will inevitably abuse it to strengthen his will in order to repress his unconscious contents, rather than exploring their many undeveloped primitive features. As purely metaphysical theory refusing the egoless state of the Hindu nivikalpa samädhi, he has radically reinterpreted Kundalini Yoga tradition and insisted on instead of practising yoga in the West to use his technique of active imagination. The research leads the author to the next main generalisations. The first, Jung did not possess sufficient knowledge of the history of Indian religious tradition and used material available to him very selectively, presenting a distorted picture of the Hindu tradition. Second, the sharp distinction or antithesis between the constitutions of the Western and Eastern psyhe is more theoretical than practical. [...
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