89,469 research outputs found

    Forma maschile, genere femminile: si presentano le donne

    No full text
    Si presenta qui la prima indagine che raccoglie dati empirici sugli usi linguistici effettivi dell’italiano in contesti reali sull'uso del genere grammaticale.L'analisi si basa su due piccoli corpora: uno di testi scritti, in cui le donne si autopresentano e uno di testi parlati in cui abbiamo sia autopre-sentazioni da parte delle donne sia donne presentate da altre donne o uomini. La scelta del genere grammaticale si intreccia con variabili di livello diamesico e diafasico, che hanno a che fare con gli aspetti relazionali e sociali della comuni-cazione linguistica, a dimostrazione del fatto che si tratta di una scelta condizionata dai rapporti interpersonali e culturali, e non semplicemente dalla grammatica della lingua. Per questo motivo abbiamo indagato le scelte linguistiche delle donne, riservando un’attenzione particolare a come le donne parlano di se stesse e in particolare quanto spazio danno al genere femminile quando si tratta del loro mondo professionale

    Regional anaesthesia for caesarean section in severe preeclampsia: spinal anaesthesia is the preferred choice

    No full text
    Part of the Portfolio Thesis by Geoffrey H. Sharwood-Smith: The inferior vena caval compression theory of hypotension in obstetric spinal anaesthesia: studies in normal and preeclamptic pregnancy, a literature review and revision of fundamental concepts, available at http://hdl.handle.net/10023/1815Standard textbooks advocate epidural rather than spinal anaesthesia for caesarean section in severe preeclampsia. The basis for this recommendation is the theoretical risk of severe hypotension but no published scientific studies have been identified to support this assertion. We therefore designed a prospective study to compare spinal versus epidural anaesthesia in severely pre-eclamptic patients requiring hypotensive therapy. Following ethics committee approval, 28 women with preeclampsia requiring hypotensive medication who were scheduled for urgent (not emergency) or elective caesarean section consented to receive epidural or spinal anaesthesia by random assignment. Seven patients were excluded due to protocol violations. Four of these were in the epidural group of which two were excluded due to inadequate analgesia. No spinal patient was excluded because of inadequate analgesia. Mean ephedrine dosage was 5.2 mg (range 0–24 mg) in the spinal group and 6.3 mg (range 0–27 mg) in the epidural group. Six of the 11 patients in the spinal group required no ephedrine as did five of 10 in the epidural group. One patient in the spinal group suffered from mild intraoperative pain. By contrast in the epidural group three patients had mild pain and four others had pain severe enough to warrant intraoperative analgesia. There were no differences in neonatal outcomes. These findings support recent studies suggesting the safety and efficacy of spinal anaesthesia in this group of patients.Publisher PD

    Retrievable vena cava filters: clinical experience

    No full text
    Purpose of review To summarize currently available literature regarding indications for inferior vena cava filters, potential problems associated with the different filters available, and the efficacy and safety of retrievable inferior vena cava filters. Recent findings The placement of permanent filters may present a number of long-term complications such as filter occlusion and an increased risk of recurrent deep vein thrombosis. Furthermore, patients who require inferior vena cava interruption often have short-term contraindications to anticoagulant therapy, and,thus only require filters for temporary indications. Four different retrievable filters have recently received approval for temporary insertion, and preliminary data suggest that the use of these filters is' associated with a low rate of pulmonary embolism and complications related to filter insertion. Retrieval was uneventful in almost all patients. No randomized clinical trials have yet been performed, and available information,is based on. the results of either retrospective or prospective, cohort studies. Summary Retrievable filters are a very attractive alternative to either permanent or temporary filters when inferior vena cava interruption becomes necessary, thanks to the advantages of very easy management and the possibility of their beings left in place for

    Fungal endocarditis in a premature infant complicated by a right atrial mycetoma and inferior vena cava thrombosis

    No full text
    The incidence of fungal endocarditis in premature infants is on the rise, reported in the last decade secondary to use of central venous lines, the frequent use of broad spectrum antibiotics and neonatal surgical interventions. Central line related thrombosis is a significant risk factor for persistent fungemia and end organ complications including endocarditis. This article presents a fatal case of progressive thrombosis of the inferior vena cava and right atrial mycetoma in a premature infant with candidemia who underwent ileostomy for bowel perforation. Renal failure occurred secondary to inferior vena cava thrombosis and right atrial mycetoma, both of which had a potential for hemodynamic compromise and embolism.peer-reviewe

    Resistant cases of psoriatic arthritis : how to manage them

    No full text
    Psoriasis is a chronic, genetically determined and immunomediated inflammatory skin disease that affects 2%-3% of the Caucasian population. Psoriatic arthritis (PsA), which occurs in up to one-third of patients with psoriasis, has a heterogeneous pattern expressed by various manifestations, including mono-oligoarthritis, an erosive and destructive polyarthritis indistinguishable from rheumatoid arthritis (RA), and spondyloarthropathy with axial involvement or enthesitis. Early detection of inflamed joints or axial involvement in patients with PsA is important in order to reduce inflammation and prevent joint destruction, deformity, and functional disability. The treatment of moderate-severe PsA has tended to include the same disease modifying antirheumatic drugs used to treat RA, but there is much less evidence supporting their efficacy and essentially none demonstrating that they slow radiographic joint destruction in PsA. A number of clinical trials have shown that tumor necrosis factor antagonists are generally safe and efficacious in the treatment of PsA, and can inhibit the progression of radiographic damage

    Extensive Pulmonary Embolism in late pregnancy associated with Anticardiolipin Antibodies

    No full text
    The leading cause of morbidity and mortality during pregnancy and the puerperium is venous thromboembolism. Though uncommon, the risk is five times higher in a pregnant woman than in a non-pregnant woman of similar age.1,2 In pregnancy, all three underlying factors for venous thrombosis are present: hypercoagulability, venous stasis and vascular damage (Virchow's triad). Of these, the most constant predisposing factor is increasing venous stasis due to the pressure of the gravid uterus on the pelvic vasculature. In addition the presence of a thrombophilia, (congenital or acquired) will increase this risk substantially. During pregnancy hypercoagulability is a physiological preparation for the haemostatic challenge of delivery. There are increases in procoagulant factors, such as von Willebrand factor, factor VIII, factor V, and fibrinogen together with an acquired resistance to activated protein C and a reduction in protein S. Increases in plasminogen activator inhibitors impair fibrinolysis. The third factor of this triad, vascular damage, is a possible complication of trophoblastic invasion of the uterine spiral arterioles or of delivery.peer-reviewe

    The HI-MAP scan : the use of emergency ultrasound to evaluate haemodynamically unstable patients

    No full text
    Includes abstract. Includes bibliographical references
    corecore