1,721,059 research outputs found
Accuracy of Papanicolaou smears in cervical cancer patients treated with radiochemotherapy followed by radical surgery.
Morphological effects of radiochemotherapy on cervical carcinoma: a morphological study of 50 cases of hysterectomy specimens after neoadjuvant treatment.
Colonic carcinoma metastatic to the endometrium: The importance of clinical history in averting misdiagnosis as a primary endometrial carcinoma
Metastases to endometrium are a rare event. A case of a 53-year-old woman with a previous colon cancer presenting with a dysfunctional uterine bleeding is reported. The curettage specimens consisted of multiple fragments of proliferative endometrial tissue mixed with irregular glands, focally amputated, lined by very cells with elongated, hyperchromatic nuclei and solid sheets of neoplastic cells often filled with necrotic debris and inflammatory cells, resembling endometrioid adenocarcinoma. Neoplastic cells resulted positive at immunohistochemical reaction for CK20, CDX2, p53 and negative for CK7, vimentin, ER, and PR suggesting a metastatic colon adenocarcinoma. Absence of premalignant changes, such as hyperplasia, besides frankly malignant glands in an endometrial curette should be regarded as an alarming feature for a secondary nature mostly from large bowel. In these cases clinical history is crucial and an immunohistochemical panel made up of CK7, CK20, CDX2, p53, vimentin, ER, and PR is useful for the correct diagnosis. © SAGE Publications 2011
Synovial chondromatosis of the temporomandibular joint with glenoid fossa erosion: disk preservation for early anatomical recovery
Background: Synovial chondromatosis (SC) of temporo- mandibular joint is a pseudoneoplastic condition characterized by benign cartilaginous metaplasia of mesenchymal residues of synovial tissue with intra articular nodules formation. TMJ involvement is rare. Interposition of loose bodies in the intra- articular space generates a pressure that could lead to glenoid fossa erosion with intracranial extension.
Findings: The aim of the study is to present 5 SC cases with intracranial extension approached with articular disk preservation. Methods: Five patients treated from 2009 to 2018, affected by TMJ chondromatosis with intracranial extension were included. Results were compared with literature. Inclusion criteria were: CT showing glenoid fossa erosion, MRI, histological SC confir- mation, and a 2-year-follow-up. Access to superior compartment was obtained. Surgical treatment was performed removing care- fully the mass and preserving articular disk. Medial region was investigated with arthroscopy.
Findings: A 2-years-follow-up showed no swelling and pain. Patients showed a good mouth opening recovery and improvement of previous mouth limitation. Morphological study, performed through MRI and CT, showed complete anatomical TMJ recovery and total bone reconstruction of the glenoid fossa.
Conclusion: The only removal of intra articular nodules, with TMJ arthroplasty and articular disk preservation, represents a valid treatment proposal for anatomic and functional full recovery in synovial chondromatosis of the temporomandibular joint with glenoid fossa erosion
Histopathological evaluation of post radio-chemotherapy response on hysterectomy specimens for cervical carcinoma
Ovarian serous carcinoma presenting with mediastinal lymphadenopathy 20 months before the intraabdominal mass: role of immunohistochemistry.
OC12.02: Long‐term dienogest administration in women with adenomyosis: effects on ultrasonographic features and symptoms
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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