945 research outputs found
Supplemental_material - Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014
No full textSupplemental_material for Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014 by Muni Rubens, Anshul Saxena, Venkataraghavan Ramamoorthy, Sankalp Das, Rohan Khera, Jonathan Hong, Donna Armaignac, Emir Veledar, Khurram Nasir, and Louis Gidel in Journal of Intensive Care Medicine</p
Art of story of Emir Kalkan
No full text1948'de Kayseri'de doğan Emir Kalkan, sadece Kayseri'nin değil Türk hikâyeciliğinin geleceğinde adından sıkça söz ettirecek önemli bir değeridir. Yazarın bu önemi, Kayseri özelinde Anadolu insanının yaşayışını, hayata bakış açısını ve psikolojisini, tüm bunlarla birlikte Kayseri'nin imkân ve imkânsızlıklarını hikâyelerinde etkili bir gözlem gücü ve kendine has üslubu ile işlemesinden ileri gelmektedir. Bütün ömrünü geçirdiği coğrafyayı ve o coğrafyanın insanlarını, değerlerini hikâyelerinde derinlemesine yansıtır. Hikâyeciliğimizde yeteri kadar yer bulamayan öz toprağının değerlerini, farklı bir soluk ve bakış açısının yanı sıra özgün bir üslûp ve sade bir Türkçe ile hikâyelerine taşır. Bu çalışmanın amacı, bir Kayseri aşığı Emir Kalkan'ı hikâyeciliği özelinde, edebî anlayışını ve Türk edebiyatına kazandırdığı eserlerini tanımak, tanıtmaktır. Anahtar Kelimeler: Emir Kalkan, Kayseri, Eserleri, Edebi Anlayış, Türk Kültürü, Şehir Hikâyeleri, Türk Tarihi ve Edebiyatı.
Born in Kayseri in 1948, Emir Kalkan who makes his mark on not only in the future of Kayseri but also in Turkish story is an important valve. The importance of author proceeds form his unique style and his effective monitoring ability in his works where he talked about the lives of the people in Anatolia, their perspective towards life and their psychology by focusing on Kayseri and besides all these things, he talked about the possibility and impossibility of Kayseri in his works. He reflects the geography where he lived for a life-spoon and people of that geography and the valves of them deeply. In his stories, he uses the valve of the territory that hasn't gained enough importance in our stories with a different perspective as well as his unique style and a pure Turkish language. The purpose of this study knows and introduces Emir Kalkan who is a lover of Kayseri by focusing on Kayseri, his literature approach and the works which he makes Turkish literature gain. Keywords: Emir Kalkan, Kayseri, Works, Literary Understanding, Turkish Culture, City Stories, Turkish Literature and History
Primary cutaneous mucinous carcinoma: a systematic review and meta-analysis of outcomes after surgery
No full textEfficacy of a needling device for the treatment of acne scars: a randomized clinical trial
No full textEffectiveness of Low Doses of Hyaluronidase to Remove Hyaluronic Acid Filler Nodules: A Randomized Clinical Trial
No full textNovel Biomarker of Oxidative Stress Is Associated With Risk of Death in Patients With Coronary Artery Disease
No full textBACKGROUND: Free radical scavengers have failed to improve patient outcomes, promoting the concept that clinically important oxidative stress may be mediated by alternative mechanisms. We sought to examine the association of emerging aminothiol markers of nonfree radical mediated oxidative stress with clinical outcomes. METHODS AND RESULTS: Plasma levels of reduced (cysteine and glutathione) and oxidized (cystine and glutathione disulphide) aminothiols were quantified by high performance liquid chromatography in 1411 patients undergoing coronary angiography (mean age 63 years, male 66%). All patients were followed for a mean of 4.7 +/- 2.1 years for the primary outcome of all-cause death (n=247). Levels of cystine (oxidized) and glutathione (reduced) were associated with risk of death (P+1 SD and CONCLUSIONS: A high burden of oxidative stress, quantified by the plasma aminothiols, cystine, glutathione, and their ratio, is associated with mortality in patients with coronary artery disease, a finding that is independent of and additive to the inflammatory burden. Importantly, these data support the emerging role of nonfree radical biology in driving clinically important oxidative stress
Vitamin D status and coronary flow reserve measured by positron emission tomography : a co-twin control study
No full textContext: Vitamin D insufficiency is associated with increased cardiovascular events in the general population. Additionally, low serum 25-hydroxyvitamin D [25(OH)D] is associated with endothelial dysfunction and arterial stiffness. However, little is known about the association between serum 25(OH)D level and myocardial blood flow. Objective: Our objective was to examine the association between serum 25(OH)D levels and coronary flow reserve (CFR) measured by N-positron emission tomography in asymptomatic middle-aged male twins. Design: The Emory Twin Study is a cross-sectional study of soldiers from the Vietnam Era Registry. Setting: The study was conducted at the General Clinical Research Center, Emory University, Atlanta, GA. Participants: A total of 368 middle-aged male twins were enrolled for the study. Serum 25(OH)D levels were measured in all subjects and classified as vitamin D insufficiency [25(OH)D <30 ng/ml] or sufficiency [25(OH)D ≥30 ng/ml]. Positron emission tomography with [ N]ammonia was used to evaluate myocardial blood flow at rest and after adenosine stress. CFR was measured as the ratio of maximum to rest myocardial blood flow. Main Outcome Measure: Primary outcome was CFR measurement. Results: Mean overall serum 25(OH)D concentration was 37.0 ± 21.4 ng/ml; 167 twins (45%) were vitamin D insufficient. CFR was significantly lower in subjects with vitamin D insufficiency compared with subjects with vitamin D sufficiency (2.41 vs. 2.64; P = 0.007), even after adjustment for traditional cardiovascular risk factors, serum PTH, calcium, and phosphorus levels, and season. An abnormal CFR (CFR <2) was more prevalent in subjects with vitamin D insufficiency than with vitamin D sufficiency (31 vs. 20%; P = 0.03). In addition, in vitamin D status-discordant twin pairs, CFR was significantly lower in the vitamin D-insufficient twin than in the vitamin D-sufficient co-twin (2.35 vs. 2.58; P = 0.037). Conclusion: Vitamin D insufficiency is associated with lower CFR in men. This association may help explain some of the increased cardiovascular risk reported in individuals with vitamin D insufficiency
Incidentally detected acromegaly: single-center study of surgically treated patients over 22 years
No full textStress Myocardial Perfusion PET Provides Incremental Risk Prediction in Patients with and Patients without Diabetes
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