1,721,038 research outputs found
Oral Microbiome, Oral Health and Systemic Health: A Multidirectional Link
Full text linkThe oral cavity can be regarded as the mirror of systemic health, since many systemic diseases may have manifestations in the oral cavity, as in the case, among oral, potentially malignant disorders, of lupus erythematosus oral lichenoid lesions, and, vice-versa, oral diseases may affect systemic health, impairing patient's nutrition and wellbeing, reducing the quality of life and increasing stress and anxiety [...].The oral cavity can be regarded as the mirror of systemic health, since many systemic diseases may have manifestations in the oral cavity, as in the case, among oral, potentially malignant disorders, of lupus erythematosus oral lichenoid lesions, and, vice-versa, oral diseases may affect systemic health, impairing patient's nutrition and wellbeing, reducing the quality of life and increasing stress and anxiety [...]
Varoni E, Tschon M, Palazzo B, Nitti P, Martini L, Rimondini L. Agarose gel as biomaterial or scaffold for implantation surgery: characterization, histological and histomorphometric study on soft tissue response.
No full textDental biomaterials and natural products represent two of the main growing
research fields, revealing plant-derived compounds may play a role not only as
nutraceuticals in affecting oral health, but also in improving physico-chemical properties of
biomaterials used in dentistry. Therefore, our aim was to collect all available data concerning
the utilization of plant polysaccharides, proteins and extracts rich in bioactive phytochemicals
in enhancing performance of dental biomaterials. Although compelling evidences are
suggestive of a great potential of plant products in promoting material-tissue/cell interface,
to date, only few authors have investigated their use in development of innovative dental
biomaterials. A small number of studies have reported plant extract-based titanium implant
coatings and periodontal regenerative materials. To the best of our knowledge, this review
is the first to deal with this topic, highlighting a general lack of research findings in an
interesting field which still needs to be investigate
Plant Products for Innovative Biomaterials in Dentistry
No full textDental biomaterials and natural products represent two of the main growing
research fields, revealing plant-derived compounds may play a role not only as
nutraceuticals in affecting oral health, but also in improving physico-chemical properties of
biomaterials used in dentistry. Therefore, our aim was to collect all available data concerning
the utilization of plant polysaccharides, proteins and extracts rich in bioactive phytochemicals
in enhancing performance of dental biomaterials. Although compelling evidences are
suggestive of a great potential of plant products in promoting material-tissue/cell interface,
to date, only few authors have investigated their use in development of innovative dental
biomaterials. A small number of studies have reported plant extract-based titanium implant
coatings and periodontal regenerative materials. To the best of our knowledge, this review
is the first to deal with this topic, highlighting a general lack of research findings in an
interesting field which still needs to be investigate
Tissue-engineered skin substitutes: an overview
No full textExtensive skin loss and chronic wounds are still a significant challenge to clinicians: even if injured epidermis is normally able to self-renew, deep injuries can cause negative regulation of the wound healing cascade, leading to chronic wound formation. Skin-autografting surgical procedures are often limited by the poor availability of healthy tissue, whereas the use of non-self-tissues for allografts presents some severe risks. Tissue-engineered skin substitutes have recently become viable as a suitable alternative to auto- and allografts. However, biologists, biochemists, and technical engineers are still struggling to produce complex skin substitutes that can readily be transplanted in large quantities. The ambitious goal is now to construct a dermoepidermal substitute that rapidly vascularizes and optimally supports a stratifying epidermal graft on a biodegradable matrix. This review analyzes these aspects in light of the available literature and the authors' experienc
Degradable polymers may improve dental practice
No full textThe use of biomaterials in dentistry is more widespread than in any other medical field in terms of both amount and variety. Most of them were not originally designed for dental applications but for other medical applications or, sometimes, for no medical purposes. Among these materials, biodegradable materials play an important role, especially in bone regeneration and in periodontal surgery. This paper briefly reviews some degradable polymers developed as tools for the treatment of periodontal and bone diseases. We discuss materials previously applied in other industrials contexts, such as polyesters, methylcellulose, and chitosan and we provide perspectives for their use in periodontal regeneration
Chronic mechanical trauma/irritation and oral carcinoma: A systematic review showing low evidence to support an association
Full text linkBackground: Chronic trauma of oral mucosa, resulting from repeated and persistent mechanical irritative action of an intraoral injury agent, has repeatedly been reported to be possibly implicated in the development of oral squamous cell carcinoma (OSCC). Objectives: The present systematic review aimed to assess whether chronic mechanical trauma can be considered a risk factor for OSCC. Data sources: PubMed, CENTRAL (Cochrane Central Register of Controlled Trials), Scopus; EMBASE, Web of Science. Study eligibility criteria: Cohort studies comparing OSCC incidence among subjects with/without chronic mechanical trauma or case–control or cross-sectional studies comparing chronic mechanical trauma among subjects with/without OSCC. Results: Only one prospective case–control study fulfilled the inclusion criteria, but the quality of the evidence provided is not enough to define trauma as a risk factor for OSCC. The main limitation is the presence of only one case–control study at high risk of bias. In the absence of strong evidence supporting the role of trauma in OSCC, a thorough discussion on trauma and carcinogenesis has been performed. Conclusions: Available evidence does not support an active role for chronic trauma in oral carcinogenesis, neither as promoter nor as progressor factor. Prospective cohort studies able to better assess trauma in OSCC are needed
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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