131,827 research outputs found
L'abbé Vallet, Les fondements de la connaissance et de la croyance
No full textV. D. L'abbé Vallet, Les fondements de la connaissance et de la croyance. In: Revue néo-scolastique. 13ᵉ année, n°52, 1906. pp. 461-462
Editorial
No full textRESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)
RESEARCHER ID M-3316-2014 (Antonio Salinas Sánchez)
ORCID 0000-0002-8408-3389 (Antonio Salinas Sánchez)
RESEARCHER ID K-8193-2014 (Alejandro Baeza)
ORCID 0000-0002-9042-8865 (Alejandro Baeza)
RESEARCHER ID K-3719-2014 (Miguel Manzano García)
ORCID 0000-0001-6238-6111 (Miguel Manzano García)Depto. de Química en Ciencias FarmacéuticasFac. de Farmaciapu
Fundamentación del Derecho y ubicación del Estado en la obra de Vallet de Goytisolo
No full textEsta tesis doctoral tiene por objeto analizar la producción filosófica-jurídica de Juan B. Vallet de Goytisolo, que fue bautizado filosóficamente por Elías de Tejada como jurisconsulto total y eximio pensador.
La tesis doctoral se encuentra dividida en cuatro capítulos fundamentales: a) el Capítulo Primero se ocupa de los presupuestos filosófico-jurídicos fundamentales en la obra de Vallet de Goytisolo, destacando entre ellos el análisis de la naturaleza humana, la naturaleza de las cosas, el sentido de la palabra “derecho”, la idea de justicia y la diferente naturaleza del Derecho respecto de sus ciencias auxiliares (Economía, Moral y Política); b) el Capítulo Segundo está dedicado al análisis de la idea de Sistema en Vallet de Goytisolo, concretamente, cuáles son sus tres elementos básicos (relación jurídica, institución jurídica y hecho jurídico) y la particular dimensión que adquieren dentro de la percepción realista de Vallet; c) el Capítulo Tercero trata de sintetizar el pensamiento político del autor desgajando sus presupuestos políticos fundamentales: como la naturaleza social del hombre, la orgánica constitución de las sociedades humanas y su estructura natural, el pactismo como medio idóneo de configuración social, etc; d) finalmente el Capítulo Cuarto muestra las conclusiones obtenidas como consecuencia del análisis realizado en los capítulo precedentes.This doctoral thesis has for object analyze the philosophical - juridical production of Juan B. Goytisolo's Vallet, which was philosophically baptized by Elías de Tejada as total lawyer and distinguished thinker.
The doctoral thesis is divided into four fundamental chapters:
a) the First Chapter deals with the philosophical - juridical fundamental assumptions in Goytisolo's work (Vallet), emphasizing on them the analysis of human nature, the nature of the things, the sense of the word “Law”, the idea of justice and the different nature of the Law with regard to its auxiliary sciences (Economy, Morality and Policy);
b) the Second Chapter is dedicated to the analysis of the system idea in Vallet by Goytisolo, concretly, which are its three basic elements (juridical relation, juridical institution and juridical fact) and the particular dimension that they acquire inside Vallet's realistic perception.
c)The Third Chapter tries to synthesize the political thought of the author tearing away his fundamental political assumptions: as the social nature of the man, the organic constitution of the human societies and natural structure, the agreements and deals like the most suitable way of social configuration etc
d) Finally the Fourth Chapter shows the conclusions obtained as consequence of the analysis realized in the previous chapters.Questa tesi dottorale ha come oggetto l’analisi della produzione filosofica-giuridica di Juan B. Vallet de Goytisolo, che fu battezzato filosoficamente da Elías de Tejada come iurisconsulto e illustre pensatore.
La tesi dottorale è divisa in quattro capitoli fondamentali: a) il primo riguarda i presupposti filosofici-giuridici fondamentali nell’opera di Vallet de Goytisolo, risaltando tra essi l’analisi della naturalezza umana, la naturalezza delle cose, il senso della parola “diritto”, l’idea di giustizia e le diverse nature del Diritto rispetto alle sue scienze ausiliari (Economia, Morale e Politica); b) il secondo è dedicato all’analisi dell’idea di Sistema in Vallet de Goytisolo, concretamente, quali sono i suoi tre elementi fondamentali (relazione giuridica, istituzione giuridica e fatto giuridico) e la particolare dimensione che acquisisce all’interno della percezione realista di Vallet; c) il terzo capitolo vuole sintetizzare il pensiero politico dell’autore sviscerando i suoi presupposti politici fondamentali come: la naturalezza sociale dell’uomo, la costituzione organica delle società umane e la sua struttura naturale, il patto come mezzo idoneo di configurazione sociale, etc.; d) infine, il quarto capitolo mostra le conclusioni ottenute come conseguenza dell’analisi nei capitoli precedenti
Nanostructures for imaging, medical diagnostics and therapy
No full textRESEARCHER ID D-9318-2017 (Juan Luis Paris de la Fuente)
ORCID 0000-0001-8950-283X (Juan Luis Paris de la Fuente)
RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)European Research CouncilMinisterio de Economía y Competitividad (MINECO)Depto. de Química en Ciencias FarmacéuticasFac. de FarmaciaTRUEpu
Éléments de mathématique [Manuscrito]
No full textMs. con la rúbrica de Domingo Madan en la h. 172r.
Ingresó en el Instituto de Canarias por donación de D. Roberto Madan en 1861
Tít. en tejuelo: Metaphysica
Foliación moderna a lápiz. En bl. 177v., 236-241, 270v., 271-272
Cada 8 h. una letra en la parte inferior del recto a modo de sign. tipográfica
Frontispicios grabados en París en el taller de Chez Vallet en la h. 1r. y representación alegórica de la metafísica en h. 17
Metaphysica sub auspicias D. Benoit philosophiae professoris in Collegio Bellovasi Parisiis [Manuscrito]
No full textMs. con la rúbrica de Domingo Madan en la h. 166v.
Ingresó en el Instituto de Canarias por donación de D. Roberto Madan en 1861
Tít. en tejuelo: Metaphysica
Foliación moderna a lápiz. En bl. las h. 1v., 2, 3r., 6v., 56v., 94v., 172v., 173-176
Cada 8 h. una letra en la parte inferior del recto a modo de sign. tipográfica
Frontispicios grabados en París en el taller de Chez Vallet en la h. 1r. y representación alegórica de la metafísica en h. 3v
MeSH term explosion and author rank improve expert recommendations
No full textInformation overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank
Self-Immolative Polymers as novel pH-responsive gate keepers for drug delivery
No full textRESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)A novel pH-sensitive nanocarrier based on mesoporous silica nanoparticles with self-immolative polymers blocking the pore openings is presented. Triggered release by acid pH is demonstrated, together with their in vitro biocompatibility and effective cell internalisation, which makes this new material a promising candidate for future applications in cancer treatment.Unión Europea. H2020European Research CouncilMinisterio de Economía y Competitividad (MINECO)Depto. de Química en Ciencias FarmacéuticasFac. de FarmaciaTRUEinpres
Mesoporous bioactive glasses for regenerative medicine.
No full textCRUE-CSIC (Acuerdos Transformativos 2021)
RESEARCHER ID M-3378-2014 (María Vallet Regí)
ORCID 0000-0002-6104-4889 (María Vallet Regí)
RESEARCHER ID M-3316-2014 (Antonio Salinas Sánchez)
ORCID 0000-0002-8408-3389 (Antonio Salinas Sánchez)Stem cells are the central element of regenerative medicine (RM). However, in many clinical applications the use of scaffolds fabricated with biomaterials is required. In this sense, mesoporous bioactive glasses (MBGs) are going to play an important role in bone regeneration because their striking textural properties, quick bioactive response and biocompatibility. As the other bioactive glasses, MBGs are mainly formed by silicon, calcium and phosphorus oxides whose ions play an important role in cell proliferation as well as in homeostasis and bone remodeling process. A common improvement of bioactive glasses for RM is by adding small amounts of oxides of elements that confer them additional biological capacities, including osteogenic, angiogenic, antibacterial, anti-inflammatory, haemostatic or anticancer properties. Moreover, MBGs are versatile in terms of the different ways in which they can be processed such as scaffolds, fibers, coatings or nanoparticles. MBGs are unique because their textural properties are so high that they still exhibit outstanding bioactive responses even after adding extra inorganic ions or being processed as scaffolds or nanoparticles. Moreover, they can be further improved by loading with biomolecules, drugs and stem cells. This article reviews the state of the art and future perspectives of MBGs in the field of RM of hard tissues.Unión Europea. Horizonte 2020Instituto de Salud Carlos III/Fondo Europeo de Desarrollo RegionalDepto. de Química en Ciencias FarmacéuticasFac. de FarmaciaTRUEpu
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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