1,720,965 research outputs found
How should a follicular adenoma with papillary architecture be classified on thyroid FNA? Case report with histological correlation
No full textMultidisciplinary diagnostic approach combining fine needle aspiration, core needle biopsy and imaging features of a presacral myelolipoma in a patient with concurrent breast cancer
No full textMyelolipomas are uncommon benign tumors composed of mature adipose tissue mixed with hematopoietic elements; these tumors can occur in both the adrenal glands and extra-adrenal locations, the presacral region being the most frequent extra-adrenal site. We present a case of presacral myelolipoma diagnosed by fine needle aspiration (FNA) and core needle biopsy (CNB) in a 55-year-old woman with concurrent invasive ductal breast cancer. TC and RM imaging were consistent with the diagnosis of presacral myelolipoma. The lesion was discovered incidentally during the staging procedure for breast malignancy. The purpose of our work is to describe the FNA and CNB finding in combination with the imaging features of this uncommon lesion
Myofibroblastoma of the breast: report of a case with radiological, cytological and histological findings
No full textBackground.
Myofibroblastoma of the breast is an uncommon
benign mesenchymal neoplasm that occurs predominantly in
elderly men.
Methods.
A 64-years-old woman presented a slowly growing lump in her left breast. A mammogram revealed a 15 mm radiopaque lesion with regular margins and no microcalcifications and ultrasonography showed well-circumscribed, oval,
hypoechoic mass measuring 28 mm, in the upper outer quadrant
of the left breast. A US-Guided Fine Needle Aspiration Cytology
(US-FNAC) was performed, showing tumour cells arranged in
cohesive groups or in fascicular clusters and, in the background,
naked nuclei. The cells were spindle shaped with a scanty amount
of cytoplasm, oval nuclei with finely granular chromatin and occasional inconspicuous nucleoli. Fragments of stromal collagen
were observed. The lesion was diagnosed as a mesenchymal
proliferation without atypia and surgical biopsy was recommended. The patient underwent a surgical excision biopsy and
histologic examination showed a 2.8 x 2.1 cm nodular mass, well-
circumscribed although not truly capsulated, firm, rubbery, with
a whirling appearance and a greyish external surface on cut sections. The slides showed a well-defined hyalinised tumour with a
spindle cell proliferation and abundant dense fibrous collagen; the
lesion was circumscribed by a thin “pseudocapsule” of compress
glandular stroma. The spindle cells were arranged in short and
haphazardly intersecting fascicles and clusters and were mixed
with broad bands of brightly eosinophilic hyalinised collagen.
Individual cells were bland-looking and showed a single ovoid
nucleus with, occasionally, one or two nucleoli. Mitotic figures
were uncommon and cytological atypia was not observed. Mast
cells were conspicuous. The spindle cells stain positively for vimentin, CD34, desmin, H-caldesmon, CD99, bcl2.
Results.
The morphologic features, in conjunction with the immunophenotype, were consistent with a myofibroblastoma of the breast (classic type)
Presacral myelolipoma in a patient with concurrent invasive ductal breast cancer diagnosed by FNC and CNB.
No full textBackground.
Myelolipomas are uncommon benign tumors composed of mature adipose tissue mixed with hematopoietic elements occuring both in adrenal glands and in extra-adrenal locations; the presacral region is the most frequent extra-adrenal location. We present the unique case of a presacral myelolipomadiagnosed by fine needle cytology (FNC) and core needle biopsy
(CNB) in a women-with a concurrent breast cancer.
Methods.
A 55 year-old women was admitted at our institution
with the cytological diagnosis of right breast cancer and a non-
characterized presacral lump. The images from a noncontrast
pelvic CT showed a 5 x 4 cm heterogeneous presacral mass
without invasion or erosion of the anterior sacrum and with mixed
fat and soft tissue attenuation. The patient uderwent a CT guided
FNC and CNB. The air-dried Diff Quick stained smears showed
trilineage hematopoietic elements in a background of mature
fat cells. The histological slides showed mature adipose tissue
admixed with cellular stroma in the absence of bone trabeculae.
The stroma consisted of myeloid, erythroid and megakaryocytic
forming cell lines.
Results.
A diagnosis of presacral myelolipoma was made on the
basis of these morphological findings in conjunction with the radiological imaging. MR imaging, recommended for further characterization, showed a lobulated mass, with mixed fat/soft tissue signal and without bony invasion. Pre-contrast fat-suppressed images showed loss of signal intensity in the areas which were previously iso-intense to fat, providing further confirmation of a significant fat component of the mass. The patient was treated only for the breast cancer with a right supero–external quadran
-tectomy and the ipsilateral axillary lymph node dissection; surgical biopsy of the presacral mass was not performed. Follow up MR at 5 and 16 months of the presacral mass showed stability of the lesion without significant interval change in size, appearance, or signal characteristics
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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