9 research outputs found

    Safety of hospital discharge before return of bowel function after elective colorectal surgery

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    Background: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function.Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien-Dindo classification system.Results: A total of 3288 patients were included in the analysis, of whom 301 (9.2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4-7) and 7 (6-8) days respectively (P < 0.001). There were no significant differences in rates of readmission between these groups (6.6 versus 8.0 per cent; P = 0.499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0.90, 95 per cent c.i. 0.55 to 1.46; P = 0.659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34.7 versus 39.5 per cent; major 3.3 versus 3.4 per cent; P = 0.110).Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients

    Safety of hospital discharge before return of bowel function after elective colorectal surgery

    No full text
    Background: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien–Dindo classification system. Results: A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4–7) and 7 (6–8) days respectively (P < 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110). Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients

    Safety and efficacy of non-steroidal anti-inflammatory drugs to reduce ileus after colorectal surgery

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    Background: Ileus is common after elective colorectal surgery, and is associated with increased adverse events and prolonged hospital stay. The aim was to assess the role of non-steroidal anti-inflammatory drugs (NSAIDs) for reducing ileus after surgery. Methods: A prospective multicentre cohort study was delivered by an international, student- and trainee-led collaborative group. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The primary outcome was time to gastrointestinal recovery, measured using a composite measure of bowel function and tolerance to oral intake. The impact of NSAIDs was explored using Cox regression analyses, including the results of a centre-specific survey of compliance to enhanced recovery principles. Secondary safety outcomes included anastomotic leak rate and acute kidney injury. Results: A total of 4164 patients were included, with a median age of 68 (i.q.r. 57–75) years (54·9 per cent men). Some 1153 (27·7 per cent) received NSAIDs on postoperative days 1–3, of whom 1061 (92·0 per cent) received non-selective cyclo-oxygenase inhibitors. After adjustment for baseline differences, the mean time to gastrointestinal recovery did not differ significantly between patients who received NSAIDs and those who did not (4·6 versus 4·8 days; hazard ratio 1·04, 95 per cent c.i. 0·96 to 1·12; P = 0·360). There were no significant differences in anastomotic leak rate (5·4 versus 4·6 per cent; P = 0·349) or acute kidney injury (14·3 versus 13·8 per cent; P = 0·666) between the groups. Significantly fewer patients receiving NSAIDs required strong opioid analgesia (35·3 versus 56·7 per cent; P < 0·001). Conclusion: NSAIDs did not reduce the time for gastrointestinal recovery after colorectal surgery, but they were safe and associated with reduced postoperative opioid requirement

    Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study

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    Aim: Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Method: This was a preplanned secondary analysis of a multicentre, prospective cohort study. Patients undergoing elective colorectal surgery between January 2018 and April 2018 were eligible. Those receiving a NGT were divided into three groups, based on the timing of the insertion: routine NGT (inserted at the time of surgery), prophylactic NGT (inserted after surgery but before vomiting) and reactive NGT (inserted after surgery and after vomiting). The primary outcome was the development of pneumonia within 30 days of surgery, which was compared between the prophylactic and reactive NGT groups using multivariable regression analysis. Results: A total of 4715 patients were included in the analysis and 1536 (32.6%) received a NGT. These were classified as routine in 926 (60.3%), reactive in 461 (30.0%) and prophylactic in 149 (9.7%). Two hundred patients (4.2%) developed pneumonia (no NGT 2.7%; routine NGT 5.2%; reactive NGT 10.6%; prophylactic NGT 11.4%). After adjustment for confounding factors, no significant difference in pneumonia rates was detected between the prophylactic and reactive NGT groups (odds ratio 1.03, 95% CI 0.56–1.87, P = 0.932). Conclusion: In patients who required the insertion of a NGT after surgery, prophylactic insertion was not associated with fewer cases of pneumonia within 30 days of surgery compared with reactive insertion

    Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study

    No full text
    Aim Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Method This was a preplanned secondary analysis of a multicentre, prospective cohort study. Patients undergoing elective colorectal surgery between January 2018 and April 2018 were eligible. Those receiving a NGT were divided into three groups, based on the timing of the insertion: routine NGT (inserted at the time of surgery), prophylactic NGT (inserted after surgery but before vomiting) and reactive NGT (inserted after surgery and after vomiting). The primary outcome was the development of pneumonia within 30 days of surgery, which was compared between the prophylactic and reactive NGT groups using multivariable regression analysis. Results A total of 4715 patients were included in the analysis and 1536 (32.6%) received a NGT. These were classified as routine in 926 (60.3%), reactive in 461 (30.0%) and prophylactic in 149 (9.7%). Two hundred patients (4.2%) developed pneumonia (no NGT 2.7%; routine NGT 5.2%; reactive NGT 10.6%; prophylactic NGT 11.4%). After adjustment for confounding factors, no significant difference in pneumonia rates was detected between the prophylactic and reactive NGT groups (odds ratio 1.03, 95% CI 0.56-1.87,P = 0.932). Conclusion In patients who required the insertion of a NGT after surgery, prophylactic insertion was not associated with fewer cases of pneumonia within 30 days of surgery compared with reactive insertion

    Safety of hospital discharge before return of bowel function after elective colorectal surgery.

    No full text
    © 2020 BJS Society Ltd Published by John Wiley & Sons LtdBackground: Ileus is common after colorectal surgery and is associated with an increased risk of postoperative complications. Identifying features of normal bowel recovery and the appropriateness for hospital discharge is challenging. This study explored the safety of hospital discharge before the return of bowel function. Methods: A prospective, multicentre cohort study was undertaken across an international collaborative network. Adult patients undergoing elective colorectal resection between January and April 2018 were included. The main outcome of interest was readmission to hospital within 30 days of surgery. The impact of discharge timing according to the return of bowel function was explored using multivariable regression analysis. Other outcomes were postoperative complications within 30 days of surgery, measured using the Clavien–Dindo classification system. Results: A total of 3288 patients were included in the analysis, of whom 301 (9·2 per cent) were discharged before the return of bowel function. The median duration of hospital stay for patients discharged before and after return of bowel function was 5 (i.q.r. 4–7) and 7 (6–8) days respectively (P < 0·001). There were no significant differences in rates of readmission between these groups (6·6 versus 8·0 per cent; P = 0·499), and this remained the case after multivariable adjustment for baseline differences (odds ratio 0·90, 95 per cent c.i. 0·55 to 1·46; P = 0·659). Rates of postoperative complications were also similar in those discharged before versus after return of bowel function (minor: 34·7 versus 39·5 per cent; major 3·3 versus 3·4 per cent; P = 0·110). Conclusion: Discharge before return of bowel function after elective colorectal surgery appears to be safe in appropriately selected patients

    0006

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    DAILY PM.O ALTO TIMES. I-KIDAV. AUGUST 15. 1913. PAGE SEVEN FREE MARKET MAY BE STARTED IN MAYFIELD Mayfleld. SnnnrTale and Mountain View were well represented at the Saa Jose Pro*- market Testerday ivtwreo thirty and forty lamier* and Krower* tram-acted bnaloe-K* at tbe i^:d-week session, _ On account of the -1.. .-*■ attained bv thr operation of the San Jose r>e-e market there Is a possibility of tbe establishment of similar Inatl* ■ i;. r. ■ In Sunnyvale, Mountain View and some of the other small loe-ir. of tb* ralley. The growers ot lhea-j ansaloni would be saved much traveling to ihelr markets if the* were* .--'.ablwhrd in these towns. Pig*, blackberries, honey, eggs. v.iter poultry, apples, peaches. plums. Bartlett pears, aprleols. to-! maioea. string beans, carrots, cabh-j age, summer spua?h. green corn.' tntnlpw and hell and red peppers, OOn sold at tbe Free market t eater- day Careful Banking Methods', Now in Vogue in California A Michigan Citv Ruled by s 3ull Moose A Southern Portia. Mt-. W H Prlion. an old lady of 75 year*, pUyed the i«n oi .-. Portia tr tenth in Atlanta. where. »he pleaded her ca*-e heii>r*- the railroid conmil- sioaerv, astcing tbat & Switch thit had bcvii removed be replaced 1'iilctu t.'H».>ti,if.n Uwycr- argued Of handed 111 tirtets in the interest: of tht- Louis riltc and Nashville road She .ro-* examined the attorneys '."! asWKIiahed ill -ah., heard her in the knowledge ol th< :.. »he exhibited WHEN A FELLER NEEDS A FRIEND. STATE SUPERINTENDENT GIVEN MUCH OF THE CREDIT. San Francisco, Aug IS —W A- tlea-sly. hank attorney and stork* holdei of Saft .lone, declares that lhe StablllU or California* banks, as demonstrated by rtt-enl events, should in* t'tk<*n as an effectual oh* Jec* leswoa of the nhm* ot careful li.tnkiiic method*! Mr tVaaal*- arg-M that State Hank Superintendent W H Williams aht.uld be -(Hen a considerable share of tbe cn-dli for the gratlfvit.** alto* atlon Wtllamn polk** bat* been thai of rigid n.«i—i*iion ever since he took * 'tar**.* ol the ofllce two yearn ago" Mplalna Renal}', and 1 think hr de- .ertes mu<h praise for hla vork Hi hunting *'»* **e«kne-*iieK snd mr recline iheni William*. ' undoubtedly helptd tini.li inward having the hank* ii-ail** (or the alien! panic Th.- wort*, that Williams has been doing fot California ml iht easily he runki-d with the splendid work the railroad ttintmission Is dolns He haa. aa a mailer of fact, net been ut..11 tt*i* . 1.-sin due him 'Williams eotorted the ..i.t law a* 11 iwad in ihe atatute*. The amend- menta ena.-t.-d b» the recent leglsta- ture relate., mmr of the unrea<*-***n- abli* limitations nf that act and at lhe same iiiii*- r«*talnn Uriel regula- Hiin t.i ibe Mat.- Member* of Ihe hanking rommii ih«i wan at Bar* inm.-nio bare told nit* thai the) re- nan t 1'f.htt.i it*, a hanking lawn now t.i In- lltr- Ileal of Dny at.lli* in lhe I nl.>n Sui..'1-ti'i-iidi-nl "A 11 llama Ma. .ii-tmi;n.*iit.i! in the r-*l..riViln* of ti.t* a. 1 Men'i Methods in Karnest \: tht nternational chatiti ■ ■-. gee. .. . .-«-n!.*,*en • »...-.... Mm. Klal.*w At* •■■•bed -.1 thi preudrm *.! tht otgaatx->ti.>n with a dag get *.n.l if ba.. *A..uitrl«**l ):.n Sh igri be. all»r Ilr as ••||Stl "-■! • f . >-*{tkl'< ll. I ..:..! I.t bet *|.. A •*!.. ...... I...-.- bad 1 >-■*.« HI .-> *.r .ri. ..»K'' ''Ut 'lie I.,I.'.! :.i-:ii> I 1)11-1 ! I ft--.*, .'!■:.III.. The '-r.l city in the United ***i..te 'J*""")" interned by the ProgrerMV pSrn' 1* Mlcgan. Mich, tlie count' seal ol Allegan county. By a substantial majority Ihr ProKtc**i»e* have elected a mayor ami .1 ronncil ol (i\e ,\ Democrat h*r been reappoint* ed 10 ihe joh <*t city night walchman. a place which he ha*, tilled "to .•■.cry- one*, satisfaction*' for 15 year*. All o: thc other offices are now held by members of tht* new patty- I»r P. v* Ca-alell ihr tti.tyor. 1. ,1 dentist and nevei had '...kiit ,m active interest in politic* until this year Thr new al dennen aie Clare K Holfm-n an ai- toene) ■**•>■. \dams.»a bookkeeper. Swan S-..n.*i a retired b titter. M l» Owen .1 nt.Unil.uHi.rr an,'. II W MetnttMh Mipenntendrni -*i Mir gin . ..-hoot. Tin* lit-Wcl »*.*. greet COEDS TO CHAPERON COLLEGE FRESHMEN -. is. .ii. -. nieub**rs of aororltles are [not .■•-..'.tt't-.i to talk with freshman glrla during the flrst five weeks of college, a eommittee of ten upper- clat*a «nnien has Iveen api*-olnted 10 form a a>nlem of apOBfOtdllp to see that the new girl* are adequately t-haperoncd during the first few days of tin* acmi'Kti'r and to help Ihem tn nn ant-1uj; ihetr euurses. I'nder each of Untie ten girls will be four .''i.r. ubo will work directly with the freahmen and report* lo these ten ho* the freahmen nre getting along. Sorority girls who are on thla committee will not be permitted to do at.. rii«.hlni5 for their clubs while aiding the freahmen. The geneta! committee of ten will be composed ot Ml***** llaxrl Green. Isabel Howell. Heen Hull in. Neoma Cheek. Ruth Price. KHa McDonald, Christine Madison, Marjorle Km* mona and Marjorie TIadale. Miss Hone Kmery of l.on Angeles was sluo appolnte*:!. but her tuiirrlage to llnic* Hllven 'OP hut. nee unit Mod Iho appointment of Miiiii> other c.l «ilh leer, it I.t*.! t,.t \llrnnti al •aay** h.*..! 1-ren a \ir..nt*bold of Ke ptildicaniant, hut il.r Progre**.)*rs s'ai net h..|l. ...il..!i ..ti.l ,,!-, -S..11.CI * Favors Rural Credits. ■An.-hlnBloti. D C AUK I-'• III an olfl.-lsl ataienieni ><-atevdnv Pri*al. d>-irt Wilaon d*x-lan*d hi- favorw "n .■•mil't-'ti* snd adei'iinte syit-tMn ol* rural credits He ggplnllMd that aiich leslalalion lx not uttiiclu*tl toi the currency hill becauai* hi- hiul | no time lo pre|-s*-e to secure eartr action In the matter Notice. Ml «h» desire to !.*t rooms to student*, during ihe .-otn'n'c M-meater ar.* re-juesled to applj at unit- In • rutin to the secretary of the public l:. .iiih committee. Stanford I'nlver- alti. fi.r room rertlfl,-alr card* niMMITTKK OS PCDMC 11 SALT 11 1,-I.'..fit I .r:::.n*. Filling (Ol Pie . .1 ..ip tloltt . tc*si>...M,l,il (,-tUl . .....t hoiltng wain \dd 1 \.i.| a ale 1 and l»>il itgblli ,.- lr.) add <h. •ll-. .if ll.ir. C«K- •slnit. beaten *titT r Pm ... ih« baked pi bake .-11 imniitr. \..lf It 1K-.....I us. II, ng Bate. ■ ■f til. (i. \V. Milll.KIl tn Mulilli'llelil l-.-a.I. tl. \V. UAIIMI AMI Homer ntenue. R. G. H. $985.00 You can pay more for a Motor Car, but yvhat more do you get? Some tacts about tho lt*C-H that yon ought to consider before >ou finally make up your mind which rar to buy: It in the most economical offered of alt low-priced cars. It la lhc essleal riding of all tow-priced carr. due lu the special arrangement of springing. It Is eieepttonally roomy, t-eatlnit (lie very comfortably. It has left-side drive with center control. II has an unusually quiet motor. * l-t inch bore with » Inch •truke Dong stroke), which can be Ihtnttled down un high speed to four milt's per hour. The I'-i-ll offers greater value, dollar for dollar, then any other car on tbe market at any where near the prl.e gOK5 fob Palo Alio. We are ilso sole agents for the celebrated Kelly-Springfield Tire I'ur further particulars call and m <■ G. W. HARMS THE BLACKSMITH Opposite the Postoffice THE WILEY B. ALLEN CO. KAN KUANCIHCO AM» SAN JOBfl High-grade Pianos and Player Pianos, Talking Machine*. A good tine of new and used instruments always on hand at The Palo Alto Branch Palo Alto Transfer office. Representative in thc city every day. Have the Times sent when you are on your vacation No trouble or expense to you. Simply call at the office of the Daily Times and have the paper changed from your home address to any place you wish to spend the Summer

    0003

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    rAOE POl'II DAILY PALC Al-Tt> TIMES. SATrKDAV, MARCH I. 191J SsUg palo Hlto glmce •ars-rr -I lU-Hu-s was sad Ba—S Mr* *' *TIM«S PL'aUSHIKC company T "mail susscairriOH gATt I gATK. Dim U Rasa Oat V*w aw M-sssaa Ta* Wtws* Oat Mewsb (LiKs al :—-u'rnlT- ** THJt DAILY -TIM Kg. Psla Alia. Cat Maws turn* abc-M .MrU iTwttsd Tilt YlfieS t. *s« r-tspew »*•*■ ««■ U •**-»■* fcy t" ^ttrr. sss JwTsM*'■'■■■- - ..** ,w l**h iSssaewi el l|/Taata.» -dl tw r-*.- I •* UK Pals Alt*. Ca* - a W SIMKINS.. 1*1.1 ■Convincing Sermon By Rev. Mr. Morgan tContinued from page I) law; aot s me-— system of ttlltb though It clan > lh* vision to see the (ruth st work building up s right life, mot s mere scstacy. though the Joy or living snd work- ~ lag wllb sacb a Friend and for sach * »i worldwide snd glotion* ends Is 1b- ^.'expressible- aot mere ethics, though whst could be more 'ethlesl' than sharing with Jesus Hla passion to bear tb* sin of the world lo sacrificial service? No, the only sure way to secure tbe full power of tbe Christian prlv- lleg* Is to let the Intlmscles and loyalties of friendship with Him 11. KELLY bring to us Ills own 'abundant' and eternal' life. Thla friendship Is at first halting, and our vision oT the unseen Friend dim. because we are hut learning 10 see and live la tbe • ptrtiaal world Bul with lore and 'orally invio'st*-. He becomes more and more real, and Ills presence more and ntOPS potent. I have • ailed you friends.' 'If a man love Me h» will keep my word, and niy father will I-,*,- blm, and we will -■me unto Him and make our abode lib Him ' Morning -*ev-vlre«t. The Christian Chwrrh sill nave t regular morning sen-ten totnorruw, wllb a sermon on "The Divine l.-iw of Progress" b> He*. I^wls A Pier In if.- evrntng the congregation playmates will attend Ihe last mission service B the pr-oc-t -A' ■n*" tnornlng *.-r*h-e of the Cotigregalional Church .George W. man or Han Francisco «i|' gjte an address Owing to Ihe mia»lon there will ha no service In Ihe eve-p- las The K-orrnni; sermon by Iter Clarence ilred ai [he Cnltarlan ChutVh will be "The (libit- of Nature" and in the rreriinK at 7 So l-i*wfea*(*i h Oray wll) lecture on Mrouk 'I Andi and' The llosaorlh hjierlan Church [ tomorrow niornln '■*- "The Chines* x-un* men ate im—tin K« CUih w|l II lopk i him •jrver It* color l-atrr chums and friends ■ .*:• «sa till each of us Is largely a pOslte of (hose w* have met, ths more intimate the friend. tbe stronger his personality, the more b* moulds us rgiher than we! mould him "This Is ihe way Christ first ■ .■!■■ Christians He chose the iwelv* to; be s Ith blm, and he aaved ihenil from aln and from (heir lower j ... -selves, to righteousness . and love and lowering influence among men. almply by living Himself into ibem In tbe Intimacies of friendship When Peter and John were later arraigned ttnfurejhe magistrates, even these hostile eyes tould mi- ibe re- semhlame and 'hey 'look know I «dge uf (bem that they had been with Jesus ' And aflei Hi*r Master * risible ••r- -■ ■.-. wa* no longer ihelrs did the) slowly rial's, bark asaln Into man nsrron iBlKftenc* and InalxoWrani** and Jury m hla n aln* Far from It So far wns Ibe'slon yeslerdl SCi't from dying (Hit IbSl ll grtiw and- heeame inv floitrWied In spite of Jewish enmltv.' with hla |n* Greek scorn nnd Roman p*ra*cu- whleh bad P Uon And why1 Simply because watering. nbje. i-d io lb* depsnare they !..:!'■*. .1 themselves still under of Mr Campbell from the pen tn tbe spell of that Illuminating In- Tact he : •■■ an ■■ sr> Insistent In his spiring masterful Presencn. Christ protvsia that he roughl) pushed hla was nrit only still alive, hiii present owner egnln«l the Mire Mr Camp- wlth Ibem And (hut ua* Hie heat hell sn- annoyed hi the ptsyrul at- truest p»an Christian wbo fell tin* i*ntlon wl ih* uruta iimll win Har- Pre-sence strongest, and was truest ri*. Ihe hired man cam* to ihe res- to ir So ail through ihe renlurie-t cue with a -,iti-h'<*rk The hull had tb* poorer for righteousness, for no horn* *o >h* r*ttlctnati i* Hitle love for noble eervlt e, that Chris- ihe worse as a result ni ihe en<-"un- llana hav* had, they say they have ter The decision sent to the bull •because somehow that Presenile ha*. . a tieea real, that personal influence Mn potent, lhat marvelous Person near vlslMtia with Mrs M K This then is Cbrfsllaallj Not field win return to her merely a code: thoiiEh ll lays S arlad Joplir. Mo TueSdS) at constraint on us more potent than hy Mr. H'-rrtford of Pa'c BULL GIVES DAIRYMAN ROUGH TREATMENT A F Campbell th* local da man narrou 1) • --. ;i;i. <] serious mil (ill Hniilllton f\> > aferuooii when »tved in nn Si tares I CROSSING MATTER WILL , BE TAKEN UP MONDAY City Attorney Norma* K. Malcolm Is determined to discover tbe cause for tbe delay In tb* matter of tb* proposed new crossing over tbe Southern Pacific tracks opposite the •nd or Palo Alto avenue. He Intends to go before the board of supervisors at tbe meeting of tbat body Monday and find out just whst la the matter While In San Francisco this week Attorney Malcolm visited the office* or the railroad commission and was told by the secretary lhat tbe petition had not been received from the supervisors. As the comnalaeton ttttOH approve tbe plsn before tbe board or supervisors takes final action. Mr Malcolm will make an effort to have the nccer-nary papers forwarded to ihe railroad commls- lon immediately Aa the legal proce*dlngs mint go through the reglar course f,na.l action on the crossing matter will not l»* taken until the oeit meeting ot au-tr-r visors Stanford Alumni Fund- Articles of iticon-oradon or the Stanford alumr.j *usd. organ lied lor ih* purpo*e of taking charge or any gifts and donation* and for investing the same were plarod on file yeMerday In the ufflre of the county clerk The assort at Ion is incorporated for a period of fifty years, snd Is st onsll- Ssn San . Palo principal place ol i-u*ln< Stanford t'alversliy Thr board of dlrertora is ei tuie.1 by N'ewton Cleveland. Francisco. Ixiuls S H'eby. Francisco Henry H Reynolds, Alio. W W Goth, Han Jos*, McDowell. Stanford Cnlverslty Mr and Mrs John Francl* Jones will be honored guests at tbe St David Clay banfjue* In San Francis co ihl* evening Mr Jones having been ndludoaied :,1 1|, 1>*kI )a*i .SaturdRi Mlsa iluhv Vanduien. from Ulas Praderfrk i. Mtirpbv a resi ale man of San Franct*n, has ; ha*.-d the It f Kavanach iilace on -iiddlrfu Id road lietwewn liaiulllon till* Poresi avenue*, and will make il- homS lliere In the (lltllN- d-irphv Is a brother : rid huslnesit isKoclate of Theodore P Mnrphy, • ho h'lU K Ii 1 the Se.i !•• It mi *e I Wtl notiliia *(;■• Th« prlr* l-sld (or Hie rtavanagh re*«idertce has not been' nade public We Have Just Received another shipment of the famous and only CEDAR SWEEP MOPS thai prove entirley satisfactory in both polishing and as a dustless mop. Come in and see the CEDAR SWEEP Palo Alto Furniture Co. Phone Pslo Alto ia. 23a Uni*rf*-raity Avenue faorissiowAL ATTORMKYB SCHOOLS. ran'AT* TVTOSI JOHN A. SQUIRB. A. S. Latin. Greek. MMtorolofy o. ii.,. 8. Trirphoa. I'. A- I Classified Advertisements WANTED. Classified Advertisements FOR RENT. Wsot«6 —Bojs Dnn* »n your old for Item—Od. s-rooSB L'.a.e .ad hlerela. .a* psrta to u so. .. -rtlll0"* '■nom b00**- tstSSts. .im . . „ ,. „ e>od s-srs*s. frail mm. ontsmsmsl PM ,oo ** for ii..,;, C. It. BS-U. ud .0.,^ ^ ,..„„»,.. .-.ni. ISI HI** str^l. Ptioo. Ilt-L^^ocioo n„r b|,b ,„„ tnmmtr 7-lt-U !fboot. IaQ.Ire «IT Em>iwu str^t. E Piar A L*1pilg gtadlo ROYAL FLINT o and Han**jon* H. gtaoford '01. Conservatory diploma. PHOJOB ITS I- Wsnted — OsrdentBg. spading.; For Kent—Alia nail, ob ths pruning; Uwos put In or gsnaral third floor of the Simkins ballding. work. Pbon* 807K. Res. :*■: Chsn'g Is available for srrall meetings st s l-Sb-lm** rental of 11 f.n per mtetlag. Bo- —: ~-— qnir* Tiroes ofl.ee. *-7-tr lamliy sewing snd mending Ukanj In. also buttonholes worked. Phone! For Reut- Urs Melody, 807K. I-J-im' i large rooms. GUITAR LESSONS MHH. A. IHEIIIUEN Kiesry HtttUf-day. I iiliemlty Hotel, I.".■in 2. Katea. i>e- lesson. ' 0 c*bU- (»I)it arrangements can b* made hy rliltlng Mrs BuehreO at st: B First St. San Joae. Wanted --Work or any kind by tKiy of 1« years. Apply Box 7, Times offle* t-M-lw* Wanted—Man to take uae of iwo 'nrge sunny housekeeping rooms tn evihnnge for some Janllor work In building Km-uirf Bos K, Times of- fli*e. z-ifi-lf . I car service. -Desirable list, rour bath, screen porch. modern conveniences. Apply 530 Cnlvsrsltjr avenue. l-5»-lro*- To LsjI—Thr-ee-room flat, com- - pletely furnished. flepsrste en-! j trance. 310 Emerson str**t. *»-t-tfl For Rent—Corner front room. e windows, aear town. 10-minute R59-Cowper. :-J5-ir' IstASSEURS John O. Varian. Masseur C<)imBCTr1 CirRTATURBg TrewU l.umt-g". sVLsilc-s, Ktc pFicttcing in I-*alo Alto niocc 19a. T<.«*n office. Madi- tniiThniis BWg; :■■'■ ;i- S90K Home office 1044 llrvant street; Shampooing Wan led- II Dt» llltiR -.1 Rgi on who iia* been i k Summer- Jiw-.h ("urtner of l.lvlng*1 ete on hiistne-.* thi* week i- --pending the ugbter, Mrs. ii ad •'Mr■ 11 Hnahieh. ompanled' month* The Regal In the latest type ot under.sliinfj struction. Underslung means Safely Can't turn Turtle con- • 1.121. F. t>. II. Palo Alio. ■VOTF. TIIK IX)W RAKISH 01 T OF IKHIV—A RACV LITTLK ItAHCAL. M'l I l> AN'I» KAKKTV. RVA1TV AMI PHACTI- CAHILITV. VANDERVOORTBROTHERS Phone 41 AND BENEPE STABLES Phone 163 AGENTS AUTOS FOR HIRE PHONE 41 * of thc lioiaii. n Plare* lefi I tup io Ridden ll HanhleEI i. reeelvinf hei father Mr >ir('e> .•Kt.lai r» are holdii g pu Tu --.day and hen (help -OtlNl pport unity to d let i e men ures Me night Iters .>r ihe open forum snd friends K it he red St Ihe liom- J Nielsen. I4"t Cowper last lo din us* the work* of Her hen Spencer Similar nieetlngn will be held every Friday nlgb< at the Nielsen home, and everyone ln- lereeted win lie welrv-me* Mi i I. c Bowie, who haa leren a San Francisco hospltfa retur*f»e< sou tiu>l e paat few week* ha or home ni Kmet hill. ft Chu Mis* Bllsabetl Cramer held I'-irtr en her fifth birthday a I Cramer home. «::, Channlng awi yrsierda> afiemoon The time was pleasantly siasnt by the following. who were present Dorothl lluller- field. Irene and (iladya rook. Ed- wine Jonas Sunda> Pan ll ns-ion. Theltna lh" kiihoill, I>>tan<l l^ong. Robert Swain and Dorothy Cramer Pleasant Thaughta. Uakr v ■' ■ ■'"■- ursts Of plea-sant tbougbta None of us -.et know what fairy pnlmt-a we may build uf is-mitl fat thoughts houses built witnout band*-for our aouls to live lu Itua - Hy tlrn'-t-ta-s cook in. references, position in fountry Addres* Miss Hoi 99 Time* office 2-2ISI*- For Rent—Furnished rooms 3t"*1 rell-j Homer avenue 2-26- ! Wanted- Position by Japanese For Rent—Two or three furnished otiple. ntsn good gardner. wife will' housekeeping room* Apply JfijiSCAliP TREATMKXT, FACIAL r*ak and wait on table Phone 420 Fverett avenue t-tt-Jf TIIKvTMKNT. I! MK WORK. iddres* 54(. Emerson st «.gs.4t«l- f._. „ , --— -mrr C MALCOLM WAD* Nn. 1 M*dUon-Thotte Block. Phone 235X For Rent -Furnished l-ro«mi— " ~~ house. ; bathrwoma. 111 Bryant MRS. U ISLITZER Complateb furniah*d bouse, i rooms] s*-P****loou*' ba'r. waru. moles r* _.*nd bath. 4CT Everett Comer!p Iddie-agedj Cowper gftd EvatwIL *unny Warned -Position by m umin (•>' geneta! house 1 rest c* M , Time* i>m<-e Ad-, -lit' Wanted Position rdener Address Menlo Park flrst-class Fattl. Hoi !-:i-iv- Phunr 6..JK ■1-1-: FOR SALE. Wanted - F1rsl-r-asa wants work by tSe day. Wednesday. Thursday and Saturday r.jC Hamo- phon na street. 2-2S-1 For Sale- -Eggs from selected hen* Royal Plymouth Rock. Rhode Island Red and White l-eghorn. tl lausdress; [*r setting i ii, Plymouth Rork 733 Addison arenu> 2-2S-JW For Wa iled- uphnlsterlng need apply It Sale—Firit-ciaag piano. in A Ki*o.J live boy to learn; excellent condition, at a reduction No cigarette smokers. Address or call st 42» Foreat *ve Itiasor. 94.1 Emerson . 2-2tMw* 3-1-lt .1 moved; pslnless I-r-ti... H and 0. '-"•-0 t'nlverwlty Ave. Hour* 10 10 4. Plum* 03*. F.lcctric Needle Operator. Chiropractic nmin-f ihe cause of disssae by relieving impingement« an vita] nerves (hu« re*tor1n-; nnrnial function in diseased pans nnd orcans V. R. BI*AN4THABI>, H. C (■raduatri (lilropnu-tor M.-.ri;'---..i Hot*!. Palo Also. Phone 772V,. And Mount*ln View. Cal, FOR SALE. For Sale—Hatching eggs, Light Itrahmas. 12 per setting; Brown leghorns. 11.50 per selling; Black Minorca*. fl.SO per setting. M. Helium. 349 High street 2-17-lm For Sale Second-hand luml also kindling wood Call form waterworks. 2-25-Iw afONKT TO MtA*. For "Bale—Dressed poultry; sliO: will buy all kinds or poultry. Correspondence lollctted. Phone 344X. E. Lodnr. 4 26 Florence. Fslo AUo 3-14-lm Money to loan on res) estate security. Rodgers «** Smith, attorneys Msdlson-Tbolts building. F. W. Sherman Upholstering and Repairing t.v-7 We hater Si Pslo Alto. Cal. MISCELLANEOUS. l-e-tr For Sale--A garage, sin feet. thoroughly lighted. moved Price 1125 9.",9WaverIey I-J4-3W H. and His Press-*-*, "II..W did you feci at that r.i-.:. <t- ble weddingr* "About s» conspicuous aa my ptckl* 1 -1 ' 1 dish looked among tbe Jeweled ',-.;./•« ,-j.ajlj.i and ropes of rsrarir*- Chicago Bs**ji**| Hsrsld PALO ALTO VACUUM CARPET CLKanim; CO Carpet laying and remodeling S 0 Glbsefl Res 1«7 I.vtton ave Phone t30Y 11-g-tf Taken Tue-dav From Fraternity Hail Is»r etetitng n tnan s gray ivereoal Return lo. 736 For Sale Turkeys and turkey eggs Juse->h (.ockwood. Mountain: View. Tasffo ranch 2-3S-2W* For Sale- A bargain—Chalmers 3fi Rosdstrr. practically new. A-l condition guaranteed. |2,2f<0 car for 1.1100.PaloAltoGarage.Phone333;224£tForSaleAgentleJerseyco325Homeravenue::.ForSalHatchingeggs:8.C.Whiteleghorns,1.1100. Palo Alto Garage. Phone 333; 2-24-£t For Sale -A gentle Jersey co 325 Homer avenue -'-'::.-• For Sal*--Hatching eggs: 8. C. White leghorns, 1..*>0 per setting; "White Hock and Orplnfftons. $S p*r setting: H C. White leghorn baby chicks. 10 rents each F. Hernaiek. Tlos 4M. Palo Alto 3-2fi-lm* For Sale—Milk from teajed Jersey cow, 2.50 a nt. P*"* tn°- not delivered. Address S€9 Channlng. 2*26*1* For Sale Thoroughbred Harred Plymouth Rock and While Minorca cockerels and pullets. Also eggs ror hatching v.ii; deliver to Palo Alto. Mali* Farm, le* Altos. Phone Pslo Alto 1446.R1. 2-2&-»t For Sale or -Trade—Ueauiirur grand piano, almost new. specially- constructed ror ramous singer; cost' Si.""". Will sell at low iii.v or: trade ror automobile. J. this ease*. I 2-tt-gt ' j Free Demonslration all Next Week LIQUID j RADIUM j the New Polish and Disinfectant ; Free Sample to Every * Lady that Calls * A\ak.ets old tt-iinKs shlrie- . with Radium-like- Brilliancy |EAP*LE_&^0. GROCERS * j Masonic Temple Buildin

    Bumblebee catfishes in Colombia: disentangling macro and microevolution in the genus Pseudopimelodus (Siluriformes: Pseudopimelodidae)

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    The Neotropical genus Pseudopimelodus (Siluriformes, Pseudopimelodidae) is the second most widely distributed genus in South America comprising four valid species that inhabit different trans- and cis-Andean rivers. Of the two species recorded in Colombia, P. schultzi is distributed in the Magdalena-Cauca and Caribbean basin and P. bufonius is distributed in the Atrato River basin and Orinoco-Amazon river basins. Several paleogeographic processes resulting from Andean orogeny in northwestern South America may promote genetic diversification in the genus Pseudopimelodus in Colombia. To test this hypothesis, we conducted phylogenetic analyses based on Bayesian Inference by using a partial sequence of the Nuclear Recombination-Activating gen (rag2) and the subunit 1 Cytochrome C Oxidase gene (COI). Furthermore, two new Pseudopimelodus species from the Magdalena-Cauca River Basin were described here based on osteological and morphometric characters: Pseudopimelodus sp. nov. 1 from Cauca River upper and middle sectors and Magdalena River upper sectors and Pseudopimelodus sp. nov. 2 from Cauca River lower sector and Magdalena River middle and lower sectors. In addition, a set of 13 microsatellites were developed by using next generation sequence technology to assess the genetic diversity and genetic structure of these two new Pseudopimelodus species. Results of Bayesian phylogenetic analyses releaved that the genus Pseudopimelodus in Colombia comprises at least five different, well-delimited evolutionary lineages, the divergence times of which agree with the geological history of northwestern South America. Moreover, microsatellite analyses showed that both new species exhibited high levels of gene flow among sample sites, and high genetic diversity compared to the mean levels of genetic diversity reported for Neotropical Siluriformes. The results obtained in this study are crucial for designing local and regional management strategies for Pseudopimelodus fisheries in Colombia.El género Neotropical Pseudopimelodus es el segundo con la más amplia distribución de la familia Pseudopimelodidae en Sur América y comprende cuatro especies válidas que habitan en diferentes ríos trans y cis-andinos. De estas cuatro especies, dos se encuentran registradas en Colombia: P. schultzi distribuida en las cuencas Magdalena-Cauca y Caribe y P. bufonius en el río Atrato y en las cuencas Amazonas y Orinoco. Diversos procesos paleogeográficos resultantes de la orogenia Andina en Suramérica noroccidental podrían promover la diversificación genética del género Pseudopimelodus en Colombia. Para contrastar esta hipótesis, en este trabajo se realizaron análisis filogenéticos basados en Inferencia Bayesiana usando secuencias parciales del gen nuclear activador de la recombinación (rag2) y de la subunidad 1 del gen de la Citocromo C Oxidasa (COI). Adicionalmente, se realizó la descripción de dos nuevas especies de Pseudopimelodus para la cuenca Magdalena-Cauca mediante el análisis de caracteres osteológicos y morfométricos: Pseudopimelodus sp. nov. 1 presente en la parte media y alta del Río Cauca y parte alta del Río Magdalena y Pseudopimelodus sp. nov. 2 que habita en la parte baja del Río Cauca y parte media y baja del Río Magdalena. Por otro lado, este estudio desarrolló un conjunto de 13 microsatélites utilizando tecnología de secuenciación de próxima generación para evaluar la diversidad y la estructura genética de estas dos nuevas especies de Pseudopimelodus. Los resultados obtenidos mediante Inferencia Bayesiana mostraron que el género Pseudopimelodus en Colombia representan al menos cinco linajes evolutivos bien delimitados, cuyos tiempos de divergencia concuerdan con la historia geológica de Suramérica noroccidental. Además, los análisis obtenidos de los microsatélites mostraron que ambas especies exhiben altos niveles de flujo genético entre los sitios muestreados y alta diversidad genética en comparación con los niveles promedios de diversidad genética reportados para Siluriformes Neotropicales. Los resultados obtenidos en el presente trabajo son de suma importancia para el diseño e implementación de estrategias regionales de manejo de las pesquerías de Pseudopimelodus en ColombiaDoctor en BiotecnologíaDoctorad
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