7 research outputs found
Analisis Permintaan Daging Sapi Di Kabupaten Jember
No full textPenelitian ini bertujuan untuk: (1) menganalisis faktor-faktor yang berpengaruh terhadap permintaan daging sapi di Kabupaten Jember, dan (2) menghitung elastisitas daging sapi di Kabupaten Jember karena harga, pendapatan dan elastisitas silang permintaan karena harga barang lain. Penelitian ini menggunakan metode deskriptif dan survei dengan pemilihan daerah dilakukan secara sengaja (purposive method), terpilih Kecamatan Sumbersari, Patrang, Kaliwates, Jelbuk, Mayang, Tempurejo, Ambulu, dan Sumberbaru. Pengambilan sampel dilakukan secara proportioned random sampling sebanyak 72 responden. Metode analisis data menggunakan teori permintaan dan analisis regresi berganda model Cobb-Douglas. Hasil penelitian menyimpulkan bahwa: (1) faktor-faktor yang berpengaruh signifikan terhadap permintaan daging sapi di Kabupaten Jember adalah harga daging sapi, harga ikan, pendapatan rumah tangga, dummy selera dan dummy wilayah penelitian, sedangkan faktor harga daging ayam ras, harga telur, tingkat pendidikan, dan jumlah anggota keluarga berpengaruh tidak nyata terhadap permintaan daging sapi di Kabupaten Jember, (2) elastisitas harga daging sapi sebesar -4,701 menunjukkan daging sapi bersifat elastis, elastisitas silang harga daging ayam, harga telur dan ikan berturut-turut sebesar 3,907; 4,416; 1,311, yang menunjukkan bahwa ketiga barang tersebut merupakan barang substitusi dari daging sapi, elastisitas pendapatan sebesar 0,579 menunjukkan daging sapi merupakan barang normal yaitu barang-barang konsumsi yang jika terjadi kenaikan pendapatan akan menyebabkan permintaan yang bertambah.
Kata kunci: Permintaan, daging sapi, elastisitas permintaan
ANALISIS FORMALISME PADA NOVEL AYAH KARYA ANDREA HIRATA
Get PDFDiscussions about efforts to understand literary works are still being developed today. To understand a work as a whole, there are many aspects that can be observed. One of them is understanding the tools and language used in literary works. Formalism is a school that was born in Russia as a form of opposition to the theoretical approach of previous literary works. According to the school of Formalism, there are two elements that can be studied in literary works related to internal mechanics and the language used in literary works. Internal mechanics examines literary works by looking at the structure and style of language used as a tool in constructing a literary work. Meanwhile, the analysis of the language of literary works is related to the defamiliarization technique used by the author in creating a story. This research uses a qualitative approach with descriptive techniques. In order to collect data, researchers used literature study with content analysis method. Sources of research data were taken from excerpts of sentences contained in the novel Ayah by Andrea Hirata. To perform data analysis, researchers used data triangulation which consisted of data collection, data presentation and drawing conclusions. The results of this study indicate that the novel Ayah by Andrea Hirata contains elements of internal mechanics and good literary language in accordance with the theory of Formalism.
Pelaksanaan Penanaman Nilai Pendidikan Karakter di SMA Bertalenta INS Kayu Tanam Kabupaten Padang Pariaman
Get PDFThis study aims to find out and analyze how the implementation of character education and the factors that influence the implementation of character education in SMA INS Kayu Tanam, Padang Pariaman Regency. This type of research is a qualitative research conducted at SMA INS Kayu Tanam with the research informants being the principal, the assembly of teachers and students or students. The data collection techniques used in this study were observation, interviews and documentation. The results of the research obtained in the field show that: 1) The implementation of character education at SMA INS Kayu Tanam can be said to be good by means of habituation carried out by students while in school and dormitory, 2) The factors that influence the implementation of character education at SMA INS Kayu Tanam can be divided into two groups, namely: a) There are those who are said to be supporting factors which include commitment and good cooperation from all parties in the school environment, both school residents who are within the school environment and parties outside the school such as the surrounding community in the school environment, b. There are what are said to be factors that hinder the implementation of character education in schools including unsupportive links, lack of school funds, lack of intense communication between the school and parents or guardians of students, lack of awareness of students who are rooted in comfort has not been able to adapt to the new environment and the lack of supervision from the school. In this case, the author suggests that the implementation of character education through habituation at SMA INS Kayu Tanam can be further improved so that the expected goals of the school by balancing brain abilities with morals can be realized
ANALYSIS OF DEMAND FOR BEEF DISTRICT OF JEMBER
Get PDFBeff is a kind of foodstuff which relatively expensive, so not every household can buy it every time. This study aimed to: (1) analyze the factors that influence demand of beef at District of Jember, and (2) calculate the elasticity on price and income of demand of beef , also cross-elasticity of demand due on prices of other goods. This study used descriptive methods and surveys with deliberate regional selection (purposive method), selected sub district were Sumbersari, Patrang, Kaliwates, Jelbuk, Mayang, Tempurejo, Ambulu, and Sumberbaru. Sampling was carried out in proportioned random sampling with total of 72 respondents, data obtained from interviews community. Data analysis method used demand theory and Cobb-Douglas model multiple regression analysis. The results of this study concluded that: (1) the factors that significantly influence demand of beef at District of Jember were price of beef and fish , household income, dummy tasts and dummy research area, while the price factor of chicken meat, prices of eggs, education level , while number of family members hae no significant effect on.; (2) beef price elasticity was -4,701 showed that elsticity of beef was elastic, cross elasticity of chicken meat price, price of eggs and fish were 3,907; 4,416; 1,311, which showed that the three items were substitutes of beef, the income elasticity of 0,579 indicates that beef was a normal item, that was consumtion goods, which was in the event of an increasing on income will caused increase demand
PCSK9 Promotes Cardiovascular Diseases: Recent Evidence about Its Association with Platelet Activation-Induced Myocardial Infarction
No full textCardiovascular diseases are the leading cause of death worldwide, with the majority of the cases being heart failure due to myocardial infarction. Research on cardiovascular diseases is currently underway, particularly on atherosclerosis prevention, to reduce the risk of myocardial infarction. Proprotein convertase subtilisin/kexin type 9 (PCSK9) has been reported to play a role in lipid metabolism, by enhancing low-density lipoprotein (LDL) receptor degradation. Therefore, PCSK9 inhibitors have been developed and found to successfully decrease LDL plasma levels. Recent experimental studies have also implicated PCSK9 in platelet activation, having a key role during atherosclerosis progression. Although numerous studies have addressed the role of PCSK9 role in controlling hypercholesterolemia, studies and discussions exploring its involvement in platelet activation are still limited. Hence, here, we address our current understanding of the pathophysiological process involved in atherosclerosis-induced myocardial infarction (MI) through platelet activation and highlight the molecular mechanisms used by PCSK9 in regulating platelet activation. Undoubtedly, a deeper understanding of the relationship between platelet activation and the underlying molecular mechanisms of PCSK9 in the context of MI progression will provide a new strategy for developing drugs that selectively inhibit the most relevant pathways in cardiovascular disease progression
High-Fat Diet Enhances Platelet Activation and Is Associated with Proprotein Convertase Subtilisin Kexin 9: An Animal Study
No full textPlatelet activation and proprotein convertase subtilisin kexin 9 (PCSK9) play pivotal roles in the progression of atherosclerosis to cardiovascular events. It has been reported that hyperlipidemia, a well-documented risk factors for cardiovascular diseases, tends increase platelet activation and PCSK9 expression. However, little is known about this specific mechanism, particularly how nutrition affects platelet activation and PCSK9 levels in hyperlipidemia conditions. This study aimed to assess how a high-fat diet influences platelet activation, its association with PCSK9, and the effects on blood pressure in an animal model. Here, male Wistar rats were divided into four groups, subjected to different high-fat diets for ten weeks with varying nutrient components. The results showed that high-fat diet-induced hypercholesterolemia and hypertriglyceridemia significantly increased the plasma levels of β-thromboglobulin (β-TG), p-selectin, and platelet factor 4 (PF-4). The blood pressure readings were also elevated post high-fat diet induction. Interestingly, the group with the highest percentage of saturated fatty acid and trans-fat exhibited the highest PCSK9 levels, along with the highest increase in plasma cholesterol, triglycerides, and platelet activation parameters. These findings confirm that high-fat diet-induced hypercholesterolemia and hypertriglyceridemia stimulate platelet activity and PCSK9 levels. Moreover, our results suggest that PCSK9, implicated in hypercholesterolemia and hypertriglyceridemia, may synergistically mediate platelet hyperactivity, aligning with clinical studies. Notably, our results highlight the association between a high-fat diet and PCSK9, providing insights for drug discovery targeting platelet activation in atherosclerosis-induced cardiovascular diseases
Recent Update on PCSK9 and Platelet Activation Experimental Research Methods: In Vitro and In Vivo Studies
No full textProprotein convertase subtilisin/kexin type 9 (PCSK9) is a crucial factor in the development and progression of cardiovascular diseases. PCSK9 has been demonstrated to modify LDL plasma levels and increase platelet activation, which promotes atherosclerosis, a defining feature of nearly all cardiovascular diseases. Platelet activation has been shown to promote and maintain the response to atherosclerosis development, from beginning to progression and exacerbation, which can lead to advanced cardiovascular events including myocardial infarction (MI) or death. Research on PCSK9 and platelet activation is currently underway with the main goal of reducing the risk of advanced cardiovascular events by preventing or slowing down atherosclerosis progression. Both in vitro and in vivo studies have been used to explore PCSK9 functions to develop new drugs targeting PCSK9. Finding the most suitable study models that represent the pathological and physiological systems found in humans is very important to achieving the goal. This review aimed to present a current and comprehensive overview of the experimental models that have been used to investigate the role of PCSK9 in platelet activation-induced atherosclerotic cardiovascular diseases
