1,721,134 research outputs found
Antihypertensive effect of spironolactone in essential ,renal and mineralocorticoid hypertension
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What Drives the Lateral Versus Vertical Propagation of Dikes? Insights From Analogue Models
No full textVolcanic eruptions are usually fed by dikes. Understanding how crustal inhomogeneities and topographic loads control the direction (lateral/vertical) and extent (propagation/arrest) of dikes is crucial to forecast the opening of a vent. Many factors, including buoyancy, crustal layering, and topography, may control the vertical or lateral propagation of a dike. To define a hierarchy between these factors, we have conducted analogue models, injecting water (magma analogue) within gelatin (crust analogue). We investigate the effect of crustal layering (both rigidity and density layering), topography, magma inflow rate, and the density ratio between host rock and magma. Based on the experimental observations and scaling considerations, we suggest that rigidity layering (a stiffer layer overlying a weaker one) and topographic gradient favor predominantly lateral dike propagation; inflow rate, density layering, and density ratio play a subordinate role. Conversely, a softer layer overlying a stiffer one favors vertical propagation. Our results highlight the higher efficiency of a stiff layer in driving lateral dike propagation and/or inhibiting vertical propagation with respect to the Level of Neutral Buoyancy proposed by previous studies
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Understanding the origin of magmatic necks: insights from Mt. Etna volcano (Italy) and analogue models
No full textMagmatic necks are commonly found in volcanic areas, and they often exhibit a homogeneous structure with a cylindrical shape and a diameter of up to several hundreds of metres. Their massive and uniform structure poses a space problem for their emplacement in the brittle crust. Here, we use field data and analogue models to investigate how necks may emplace at shallow levels. Field analysis focuses on characterising the geometric, structural and magmatic features of two necks outcropping in the eroded portions of Mt. Etna, Italy. These are homogeneous and massive intrusive bodies, related to a single episode of emplacement at 400–600 m below the paleosurface. We further investigated their possible emplacement mechanism through analogue models, injecting vegetable oil within (a) a flat sand pack and (b) a sand cone. Dikes form with both configurations, erupting to the surface through vents. However, dikes injected within the cone are characterised by a larger thickening at shallow levels, in correspondence with the vent, where a neck-like structure forms. This suggests that the gravitational load imposed by a volcanic edifice provides the most suitable conditions for the development of magmatic neck, as the downslope shear stresses enhance the deformation of the cone slope during shallow dike emplacement promoting shallow dilation and thickening of the dike. Therefore, topography should be a further factor enhancing the development of necks, in addition to those mechanisms previously proposed. Our results are consistent with natural examples of feeder dikes thickening towards the surface and dikes transitioning to necks, supporting the reliability of the proposed conceptual model
The role of anti-core antibody response in the detection of occult hepatitis B virus infection
No full textOccult hepatitis B virus (HBV) infection is characterized by the presence of HBV DNA in serum and/or in the liver of patients negative for hepatitis B surface antigen (HBsAg). Occult infection may impact in several different clinical contexts including the risk of HBV transmission with transfusion or transplantation, and endogenous viral reactivation. The gold standard test for detection of occult infection is the amplification of HBV DNA. However, the serological assay for the long-lasting antibody response to the highly immunogenic HBV core antigen (anti-HBc) represents a qualified candidate as a surrogate for DNA amplification, or for increasing overall sensitivity when assessing the risk of occult hepatitis in peripheral blood. The risk of occult hepatitis associated with anti-HBc seropositivity has been demonstrated extensively, and the presence of antibody response to HBc can be considered a sentinel marker of occult HBV infection. Clin Chem Lab Med 2010; 48: 23-9
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