32 research outputs found
Search-based multi-vulnerability testing of XML injections in web applications (vol 24, pg 3696, 2019): Search-based multi-vulnerability testing of XML injections in web applications (Empirical Software Engineering, (2019), 10.1007/s10664-019-09707-8)
No full textThe article Search-based multi-vulnerability testing of XML injections in web applications, written by Sadeeq Jan, Annibale Panichella, Andrea Arcuri, and Lionel Briand, was originally published electronically on the publisher’s internet portal (currently SpringerLink) on May 2019 without open access. With the author(s)’ decision to opt for Open Choice the copyright of the article changed on June 2019 toSoftware Engineerin
IMPACT OF AUDIT QUALITY ON EARNING MANAGEMENT: A CASE OF CEMENT INDUSTRY
No full textThe present study aimed to investigate the impact of audit quality (i.e., firm size, auditor tenure, audit committee financial expertise, and client importance) on earnings management in the cement industry firms listed on the Pakistan Stock Exchange. A quantitative and descriptive research design was employed in this study. The population for the study comprised of firms in the cement industry sector listed on the Pakistan Stock Exchange. A total of 14 firms were selected using a convenient sampling technique. Data for the study was collected from 2005 to 2019, covering a 15-year period. The study\u27s findings suggest that organizations should ensure that their auditors possess expertise in the industry they are auditing. This, when combined with the audit committee members\u27 accounting and financial experience, can mitigate earnings management, especially in complex business environments
Green synthesis of catalytic Zinc Oxide nano‐flowers and their bacterial infection therapy
No full textSearch-based Multi-Vulnerability Testing of XML Injections in Web Applications
No full textpeer reviewedModern web applications often interact with internal web services, which are not directly accessible to users. However, malicious user inputs can be used to exploit security vulnerabilities in web services through the application front-ends. Therefore, testing techniques have been proposed to reveal security flaws in the interactions with back-end web services, e.g., XML Injections (XMLi). Given a potentially malicious message between a web application and web services, search-based techniques have been used to find input data to mislead the web application into sending such a message, possibly compromising the target web service. However, state-of-the-art techniques focus on (search for) one single malicious message at a time.
Since, in practice, there can be many different kinds of malicious messages, with only a few of them which can possibly be generated by a given front-end, searching for one single message at a time is ineffective and may not scale. To overcome these limitations, we propose a novel co-evolutionary algorithm (COMIX) that is tailored to our problem and uncover multiple vulnerabilities at the same time. Our experiments show that COMIX outperforms a single-target search approach for XMLi and other multi-target search algorithms originally defined for white-box unit testing.tun
An eco-benign synthesis of AgNPs using aqueous extract of Longan fruit peel: Antiproliferative response against human breast cancer cell line MCF-7, antioxidant and photocatalytic deprivation of methylene blue
No full textFunctionalization of Se-Te Nanorods with Au Nanoparticles for Enhanced Anti-Bacterial and Anti-Cancer Activities
No full textThe use of medical devices for therapeutic and diagnostic purpose is globally increasing; however, bacterial colonization on therapeutic devices can occur, causing severe infections in the human body. It has become an issue for public health. It is necessary to develop a nanomaterial based on photothermal treatment to kill toxic bacterial strains. Appropriately, high photothermal conversion and low-cost powerful photothermal agents have been investigated. Recently, gold nanocomposites have attracted great interest in biological applications. Here, we prepared rod-shaped Se-Te@Au nanocomposites of about 200 nm with uniform shape and surface-coated with gold nanoparticles for the first time showing high anti-bacterial and anti-cancer activities. Se-Te@Au showed proper structural consistency and natural resistance to bacterial and cancer cells. The strong absorption and high photothermal conversion efficacy made it a good photothermal agent material for the photothermal treatment of bacterial and cancer cells. The Se-Te@Au rod showed excellent anti-bacterial efficacy against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus, with highest recorded inhibition zones of 25 ± 2 mm and 22 ± 2 mm, respectively. More than 99% of both types of strains were killed after 5 min with a near-infrared (NIR) laser at the very low concentration of 48 µg/mL. The Se-Te@Au rod’s explosion in HeLa cells was extensively repressed and demonstrated high toxicity at 100 µg/mL for 5 min when subjected to an NIR laser. As a result of its high photothermal characteristics, the exceptional anti-bacterial and anti-cancer effects of the Se-Te@Au rod are considerably better than those of other methods previously published in articles. This study could open a new framework for sterilization applications on the industrial level
Molecular mechanism of tobramycin with human serum albumin for probing binding interactions: multi-spectroscopic and computational approaches
No full textHighlighting novelty: comprehensive in vitro and in silico insights for understanding the novel binding site of TOB with HSA.</p
Understanding microbiota-driven oncogenesis: The role of metabolites in tumorigenesis
No full textSummary: The gut microbiota profoundly influence human health through its composition and metabolic activity, which are shaped by diet and host factors. Disruption of this equilibrium, known as dysbiosis, has been implicated in cancer development. Microbial metabolites act as key mediators connecting the gut microbiome to tumor progression by altering the tumor microenvironment and modulating signaling pathways in tumor and immune cells. This review examines the mechanistic links between the gut microbiota, its metabolites, and tumorigenesis, emphasizing how microbial metabolism of host- and diet-derived compounds affects oncogenic and genotoxic processes in colorectal cancer (CRC). It also explores how dietary and host factors modulate microbial composition and function, influencing cancer susceptibility. Understanding these interconnected processes provides conceptual insight into the microbiota-cancer axis and highlights opportunities for microbiome-targeted interventions in cancer prevention and therapy
Recent Advances in the Surface Functionalization of Nanomaterials for Antimicrobial Applications
No full textInnovations in nanotechnology have had an immense impact on medicine, such as in drug delivery, tissue engineering, and medical devices that combat different pathogens. The pathogens that may cause biofilm-associated nosocomial diseases are multidrug-resistant (MDR) bacteria, such as Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa), Staphylococcus aureus (S. aureus), including both Gram-positive and Gram-negative bacterial species. About 65–80% of infections are caused by biofilm-associated pathogens creating a move in the international community toward developing antimicrobial therapies to eliminate such pathogenic infections. Several nanomaterials (NMs) have been discovered and significantly employed in various antipathogenic therapies. These NMs have unique properties of singlet oxygen production, high absorption of near-infrared irradiation, and reasonable conversion of light to heat. In this review, functionalized NPs that combat different pathogenic infections are introduced. This review highlights NMs that combat infections caused by multidrug-resistant (MDR) and other pathogenic microorganisms. It also highlights the biomedical application of NPs with regard to antipathogenic activities
