1,720,966 research outputs found
Diabetic myonecrosis: imaging findings illustration and literature review
No full textWe illustrate the imaging findings of Diabetes Muscle Infarction (DMI), a rare complication of
longlasting and poorly controlled Diabetes Mellitu
Current Role Of Hepatopancreatoduodenectomy For The Management Of Gallbladder Cancer And Extrahepatic Cholangiocarcinoma: A Systematic Review
Full text linkBACKGROUND Hepatopancreatoduodenectomy (HPD) is the simultaneous combination of hepatic resection, pancreaticoduodenectomy, and resection of the entire extrahepatic biliary system. HPD is not a universally accepted due to high mortality and morbidity rates, as well as to controversial survival benefits. AIM To evaluate the current role of HPD for curative treatment of gallbladder cancer (GC) or extrahepatic cholangiocarcinoma (ECC) invading both the hepatic hilum and the intrapancreatic common bile duct. METHODS A systematic literature search using the PubMed, Web of Science, and Scopus databases was performed to identify studies reporting on HPD, using the following keywords: ‘Hepatopancreaticoduodenectomy’, ‘hepatopancreatoduodenectomy’, ‘hepatopancreatectomy’, ‘pancreaticoduodenectomy’, ‘hepatectomy’, ‘hepatic resection’, ‘liver resection’, ‘Whipple procedure’, ‘bile duct cancer’, ‘gallbladder cancer’, and ‘cholangiocarcinoma’. RESULTS This updated systematic review, focusing on 13 papers published between 2015 and 2020, found that rates of morbidity for HPD have remained high, ranging between 37.0% and 97.4%, while liver failure and pancreatic fistula are the most serious complications. However, perioperative mortality for HPD has decreased compared to initial experiences, and varies between 0% and 26%, although in selected center it is well below 10%. Long term survival outcomes can be achieved in selected patients with R0 resection, although 5–year survival is better for ECC than GC. CONCLUSION The present review supports the role of HPD in patients with GC and ECC with horizontal spread involving the hepatic hilum and the intrapancreatic bile duct, provided that it is performed in centers with high experience in hepatobiliarypancreatic surgery. Extensive use of preoperative portal vein embolization, and preoperative biliary drainage in patients with obstructive jaundice, represent strategies for decreasing the occurrence and severity of postoperative complications. It is advisable to develop internationally-accepted protocols for patient selection, preoperative assessment, operative technique, and perioperative care, in order to better define which patients would benefit from HPD
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Primary epidural lumbo-sacral non Hodgkin Lymphoma (NHL): MRI features and literature review
No full textWe describe RM features of primary epidural NHL and illustrate the most important
differential criteria from extra-dural tumour
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Superficial hemosiderosis of central nervous system (CNS) in cerebral amyloid angiopathy (CAA).
No full textIn this educational exhibit we want to underline the role of this microangiopathic disease
as a potential pathomechanism for superficial hemosiderosis (SS) and to illustrate the
related neuroimaging features in SS of the central nervous system as a new prospective
MR diagnostic marker of CAA
Characterization of focal liver lesions in real time using harmonic imaging with high mechanical index and contrast agent levovist
No full textAppropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
L’Angiopatia cerebrale amiloide correlata all’infiammazione (CAA-IR) alla RM: caso clinico e revisione della letteratura
No full textObiettivi Didattici:
Illustrare gli aspetti RM della CAA-IR, sottotipo della CAA con sintomatologia e terapie specifiche.
Introduzione:
La diagnosi di CAA diviene probabile in anziani normotesi con clinica indicativa ed evidenza RM di
multipli depositi emosiderinici parenchimali. Nei Pazienti con genotipo APOE ?4-?4 è più frequente lo
sviluppo di alterazioni infiammatorie. Riportiamo i reperti diagnostici RM in un caso di un uomo che
ha mostrato successivamente netto miglioramento dopo terapia steroidea.
Tecnica d'esame e/o riscontri all'imaging:
Uomo di 81 aa, con crisi epilettica generalizzata e sindrome cognitiva frontale; proteinoracchia in
assenza di cellule o di positività del liquor a microrganismi (JCV compreso). La RM mostrava aree di
iperintensità in T2 ed ipointensità in T1 della s. bianca periventricolare-sottocorticale degli emisferi
cerebrali, a distribuzione asimmetrica, di aspetto digitato con estensione alla giunzione s. bianca-s.
grigia, in parte con effetto massa, prevalenti in sede frontale sinistra, in assenza di enhancement o
di restrizioni della diffusione ma incremento del segnale ADC. Inoltre la GE T2* mostrava molteplici
depositi emosiderinici sottocorticali in entrambi gli emisferi con risparmio dei nuclei della base e
delle strutture sottotentoriali.
Conclusioni:
Nella valutazione del Pz anziano risulta opportuno tenere alto il sospetto di CAA, sottostimata ed
importante causa di emorragie spontanee cerebrali per il cui rilievo risulta indispensabile l’impiego
della GE T2. In particolare nei casi in cui al riscontro dei tipici microdepositi di emosiderina si associ
un quadro di leucoencefalopatia con coinvolgimento delle fibre ad U è lecito ipotizzare la variante
infiammatoria CAA-IR
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