2,200 research outputs found
"Studi gregoriani". Recensione a A. TURCO, "La scrittura musicale del canto gregoriano", Verona, 2006
No full textsul metodo gregoriano di A. Turco, di cui si apprezza l'aggiornamento didattico su semiologia, segno e circa gli aspetti modal
Conference The Development of a Digital Cultural Heritage Eco-system / Congresso Lo sviluppo di un eco-sistema digitale del patrimonio culturale
No full textFollowing a twenty-year tradition, March in Ferrara is dedicated to the themes of Restoration and Cultural Heritage: three days of conferences, exhibitions, debates and working tables in an event that precedes the contents of the XXVI Salone del Restauro, dei Musei e delle Imprese Culturali, this year scheduled on September, 18th, 19th and 20th. In the framework of palazzo Tassoni Estense, numerous moments of discussion were proposed on the themes of restoration, architectural heritage, design, research and governance of the territories, with particular attention to the Emilia territory affected by the seismic events of 2012. (read more
Il ruolo del gradiente di pressione venoso epatico nell'era moderna della cirrosi: nuove eziologie e una popolazione target di pazienti da esplorare
No full textI beta-bloccanti non selettivi (NSBB), riducendo la pressione portale (misurata mediante HVPG), possono prevenire le complicazioni della cirrosi. Tuttavia tutti gli studi condotti sinora hanno combinato pazienti con cirrosi compensata e scompensata e sono stati condotti in un’era in cui la maggior parte dei pazienti aveva una cirrosi virus correlata. Oggi la maggior parte dei pazienti ha una cirrosi NASH-correlata, la cui ipertensione portale non sembra essere completamente misurabile con l’HVPG che sembra quindi non essere in grado di predirne lo scompenso.
Obiettivi Primo studio. Per valutare i vantaggi della risposta ai NSBB mediante HVPG separatamente in pazienti con cirrosi compensata e scompensata. Secondo studio. Per valutare la concordanza tra l’HVPG e la misurazione diretta della pressione portale (PP) nei pazienti con cirrosi NASH rispetto a quelli con cirrosi alcoolica o da HCV. Terzo studio. Per esaminare la relazione tra HVPG e lo scompenso epatico nei pazienti con cirrosi NASH confrontati con quelli con cirrosi HCV.
Metodi Primo studio.
Una meta-analisi con dati di pazienti cirrotici inclusi in studi che valutavano gli outcomes in pazienti con risposta all’HVPG vs quelli senza risposta divisi in cirrosi compensata e scompensata. Secondo studio. Studio multicentrico cross-sezionale che include i pazienti con cirrosi NASH trattati con TIPS dal 2010 al 2019, confrontati con due controlli con cirrosi alcolica o da HCV. Terzo studio. Studio multicentrico comprendente i pazienti con cirrosi NASH con una HVPG misurata tra il 2014 e il 2018 confrontati con quelli con cirrosi HCV in termini di eziologia, HVPG e scompenso.
Risultati Primo studio.
Dati da 15 studi (1113 pazienti) in profilassi per il sanguinamento da varici che hanno riportato gli outcomes in HVPG responders vs. non-responders ai NSBB. In pazienti senza ascite, i responders avevano una minore probabilità di sviluppare complicanze dei non-responders (OR 0.35; 95% CI, 0.22–0.56) e di morte/trapianto di fegato (OR 0.50, 95% CI, 0.32–0.78). Nei pazienti con ascite, i responders avevano una minore probabilità di sviluppare complicanze dei non-responders (OR 0.27; 95% CI, 0.16–0.43) e di morte/trapianto di fegato (OR 0.47; 95% CI, 0.29–0.75). Secondo studio. Pazienti con cirrosi NASH scompensata (n=40) confrontati con pazienti con cirrosi scompensata da alcool (n=40) o HCV (n=40). La correlazione tra la pressione bloccata della vena epatica (WHVP) e la PP è eccellente nel gruppo di controllo (R: 0.92; ICC: 0.96; p<0.001). Nel gruppo NASH la correlazione è solo moderata (R: 0.61; ICC: 0.74; p<0.001). All’analisi multivariata, l’eziologia NASH è stata significativamente associata con questa mancata correlazione [OR: 4.03 (95% CI 1.60–10.15); p=0.003]. Terzo studio. I pazienti con cirrosi NASH e HCV avevano una simile età, sesso, CPT e MELD. L’HVPG media era più bassa nel gruppo NASH (13 vs 15 mmHg) invece gli eventi di scompenso e le varici ad alto rischio erano maggiori (32% vs 25% p=0.019 and 32% vs 27%, p=0.103). Il gruppo NASH aveva una HVPG più bassa (17 vs 19mmHg p=0,001) ma una mggiore prevalenza di scompenso per ogni livello di HVPG.
Conclusioni Primo studio. I pazienti con cirrosi con o senza ascite che sono NSBB- HVPG responder hanno un rischio ridotto di eventi e di morte. Secondo studio. Nei pazienti con cirrosi NASH scompensata, WHVP sottostima PP. Terzo studio. I pazienti con cirrosi NASH hanno una maggiore prevalenza di scompenso per ogni valore di HVPG rispetto a quelli con cirrosi HCVBackground Nonselective b-blockers (NSBB), by reducing portal pressure gradient (measured by HVPG), may prevent disease complications. However, all studies carried out so far combined patients with compensated and decompensated cirrhosis and were conducted in an era where the majority of patients had virus related cirrhosis. Nowadays the majority of patients have a NASH-related cirrhosis, but their portal hypertension seems not to be fully captured by HVPG, therefore HVPG may be not able to predict their decompensation.
Objectives First study. To assess the benefits of NSBBs-HVPG response in patients with compensated or decompensated cirrhosis separately. Second study. To evaluate the agreement between HVPG and direct measure of portal pressure gradient (PP) in patients with NASH cirrhosis compared to those with alcohol or HCV-related cirrhosis. Third study. To examine the relationship between HVPG and hepatic decompensation in patients with NASH-cirrhosis compared to those with HCV-related cirrhosis.
Methods First study.
A meta-analysis with data from patients with cirrhosis included in studies that assessed outcomes in HVPG responders and non-responders divided in patients with compensated or decompensated cirrhosis. Second study. Multicenter cross-sectional study including all patients with NASH cirrhosis treated with TIPS from 2010 to 2019, matched with two controls with alcohol or HCV-related cirrhosis. Third study. Multicenter study including all patients with NASH-related cirrhosis with an HVPG measured from 2014 to 2018 compared to those with HCV related-cirrhosis in terms of etiology, HVPG and decompensation.
Results First study.
Data from 15 studies (1113 patients) of prophylaxis of variceal bleeding that had reported on outcomes in HVPG responders vs. non-responders to NSBB. In patients without ascites, responders had lower odds of events than nonresponders (OR 0.35; 95% CI, 0.22–0.56) and death/liver transplant (OR 0.50, 95% CI, 0.32–0.78). In patients with ascites, responders had lower odds of events than nonresponders (OR 0.27; 95% CI, 0.16–0.43) and death/liver transplant (OR 0.47; 95% CI, 0.29–0.75). Second study. Patients with decompensated NASH cirrhosis (n=40) compared with matched patients with decompensated cirrhosis due to alcohol (n=40) or HCV (n=40). Correlation between wedged hepatic venous pressure (WHVP) and portal pressure (PP) was excellent in the control group (R: 0.92; ICC: 0.96; p<0.001). Agreement was only moderate in the NASH group (R: 0.61; ICC: 0.74; p<0.001). At multivariate analysis, NASH etiology was independently associated with this disagreement [OR: 4.03 (95% CI 1.60–10.15); p=0.003]. Third study. Patients with NASH-related and HCV-related cirrhosis had similar age, gender, CPT and MELD. Median HVPG was lower in NASH group (13 vs 15 mmHg) beside rates of clinical decompensation and high-risk varices were higher in NASH group (32% vs 25% p=0.019 and 32% vs 27%, p=0.103). NASH group had lower HVPG (17 vs 19mmHg p=0,001) and higher prevalence of decompensation for any HVPG threshold.
Conclusion First study. Patients with cirrhosis, with or without ascites, who have NSBB induced- HVPG reduction are at lower risk for adverse events or death. Second study. In patients with decompensated NASH cirrhosis, WHVP underestimates PP. Third study. Patients with NASH cirrhosis have higher prevalence of decompensation at any value of HVPG compared to patients with HCV-cirrhosis
The Officina Emilia Initiative:Innovative Local Actions to Support Education and Training Systems
No full textThe issue of the regeneration of skills, in particular in the light engineering industry, is addressed by Officina Emilia (henceforth OE) as a crucial one in order to re-examine the interweaving of education, innovation and local development in the SMEs production systems. The project, aimed at the education and training systems, is designed to enhance the industrial culture in order to strengthen technical and scientific education. First sponsored in 2000 by the University of Modena & Reggio Emilia (Italy), over the last years OE has gathered the support of local actors dealing with the themes of training, culture, and local development. In 2009 it opened its museolaboratorio (“workshop-museum”) in which teaching activities promote an interest in the themes of work, technologies and the socio-economic development of the territory among the students and teachers of schools of all types and levels. The involvement of class groups, of teachers and other visitors takes place through active learning practices that foster motivation and develop a sense of belonging which is likely to lead to a more profitable educational experience, both secondary and tertiary, as well as to contribute to improving career prospects. Officina Emilia proposes innovative action on a local level, allowing for the implementation of effective teaching practices as well as the broadening and consolidation of best practices which might support a society-wide trend towards maintaining a high demand for a better quality of education and the ability to provide it. Ten years after the beginning of the initiative, with this paper we intend to open up the discussion on the various research issues and on the actions undertaken, focusing on the analytical tools and the main critical areas in the further implementation of the Officina Emilia initiative.Analysis of Education; Education Policy; Regional Development Policies; Innovation
Emilia Pardo Bazán and the fight for women’s rights: an analysis of her non-fiction production and of Morriña
No full textopenLa presente tesi si propone di analizzare il ruolo della donna nella Spagna del XIX secolo, un ruolo essenzialmente limitato all’ambiente domestico e che attribuisce alla donna una posizione di sottomissione rispetto alla figura maschile. Nella società spagnola del XIX secolo, la donna non gode degli stessi diritti dell’uomo e l’unica sua aspirazione è il matrimonio. Nel panorama letterario a cavallo tra XIX e XX secolo emerge la figura di Emilia Pardo Bazán, un’autrice che, nel corso della sua vita e della sua produzione letteraria, ha lottato per la difesa dei diritti della donna. L’autrice sostiene la causa femminista e crede fermamente che l’accesso delle donne all’istruzione e al mondo del lavoro consentirebbero il progresso della nazione e permetterebbero inoltre alle stesse di raggiungere l’emancipazione. Il romanzo Morriña (1889) di Emilia Pardo Bazán, attraverso la storia della domestica Esclavitud Lamas, descrive la condizione della donna dell’epoca e i pregiudizi tipici di una società patriarcale.The aim of the present thesis is to analyze the role of the woman in the 19th century Spain, a role mainly limited to the home environment and which attributes to the woman a position of submission to the male figure. In the 19th century Spanish society the woman does not enjoy the same rights as man and her only aspiration is marriage. In the literary scenario between the 19th and the 20th century stands out the figure of Emilia Pardo Bazán, an author who, throughout her life and her literary production, has fought for women’s rights. The author supports the feminist cause and she firmly believes that women’s access to education and work would provide the country’s progress and would help women achieve emancipation. The novel titled Morriña (1889) by Emilia Pardo Bazán, through the history of the maid Esclavitud Lamas, describes the condition of the woman during that time and the prejudices of a patriarchal society
L’impero americano: guerra e decadenza
No full textThe essay examines some recent interpretations of American civilization in terms of empire and decline, and shows that they are constant themes in the European reception of the United States of America.Il saggio prende in esame alcune recenti interpretazioni della civiltà americana in termini di impero e di declino, e mostra che si tratta di costanti nella ricezione europea degli Stati Uniti d’America
Emilia Salvioni
No full textThe headword explains the biography and the contribution of the author Emilia Salvioni to the children's literatur
Emilia Formìggini Santamaria
No full textThe headword explains the biography and the contribution of the author Emilia Formìggini Santamaria to the children's literatur
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