1,721,176 research outputs found
Google search behavior for status epilepticus.
No full textBackground: Millions of people surf the Internet every day as a source of health-care information looking for materials about symptoms, diagnosis, treatments and their possible adverse effects, or diagnostic procedures. Google is the most popular search engine and is used by patients and physicians to search for online health-related information. This study aimed to evaluate changes in Google search behavior occurring in English-speaking countries over time for the term “status epilepticus” (SE).
Methods: Using Google Trends, data on global search queries for the term SE between the 1st of January 2004 and 31st of December 2014 were analyzed. Search volume numbers over time (downloaded as CSV datasets) were analyzed by applying the “health” category filter.
Results: The research trends for the term SE remained fairly constant over time. The greatest search volume for the term SE was reported in the United States, followed by India, Australia, the United Kingdom, Canada, the Netherlands, Thailand, and Germany. Most terms associated with the search queries were related to SE definition, symptoms, subtypes, and treatment. The volume of searches for some queries (nonconvulsive, focal, and refractory SE; SE definition; SE guidelines; SE symptoms; SE management; SE treatment) was enormously increased over time (search popularity has exceeded a 5000% growth since 2004).
Conclusions: Most people use search engines to look for the term SE to obtain information on its definition, subtypes, and management. The greatest search volume occurred not only in developed countries but also in developing countries where raising awareness about SE still remains a challenging task and where there is reduced public knowledge of epilepsy.
Health information seeking (the extent to which people search for health information online) reflects the health-related information needs of Internet users for a specific disease. Google Trends shows that Internet users have a great demand for information concerning some aspects of SE (definition, subtypes, symptoms, treatment, and guidelines). Policy makers and neurological scientific societies have the responsibility to try to meet these information needs and to better target public information campaigns on SE to the general population
Antiepileptogenesis in humans: disappointing clinical evidence and ways to move forward.
No full textPURPOSE OF REVIEW: Preclinical research in epileptology has been very successful in developing antiseizure drugs (ASDs). Several preclinical proof-of-concept studies have also provided evidence for positive treatment effects of some antiepileptogenic drugs to prevent the development of epilepsy. Disappointingly, all human antiepileptogenesis trials to prevent epilepsy after brain insults have failed, because of several reasons.
RECENT FINDINGS: None of the currently available ASDs have been shown to prevent epilepsy after stroke, traumatic brain injury, or in brain tumours. Retrospective series and post-hoc analyses of randomized controlled trials of patients undergoing combined radiochemotherapy for malignant glioblastoma found an increased survival of patients with valproate, thus suggesting a possible role against the symptoms related to the comorbidity of epilepsy in these patients. Target-oriented treatments such as rapamycin and everolimus are currently under clinical investigation to prevent epilepsy in patients with tuberous sclerosis.
SUMMARY: An orchestrated effort among basic and clinical scientists is needed to develop proper antiepileptogenic drugs, powerful biomarkers, and valid clinical trial designs to bring new treatments on the market that can successfully prevent epilepsy
Lessons from the past: Hyperthermia in status epilepticus in the first descriptions by Désiré-Magloire Bourneville (1840-1909)
No full text[no abstract available
Comparative efficacy of antiseizure medications for the treatment of uncontrolled focal seizures
No full text
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A coleção "Trinka e João": O grande fogo; o dia em que a terra tremeu
Full text linkA ocorrência de desastres naturais pode ser desafiante para crianças e educadores. É descrita uma experiência educativa que utiliza histórias como estratégia para lidar com o stress que estes acontecimentos podem despoletar. Neste âmbito, surge a experiência educativa da coleção ‘Trinka e João’, designadamente com os livros O Grande Fogo e O Dia em que a Terra Tremeu, que visa sensibilizar e capacitar pais e educadores e proporcionar o contacto e a utilização de recursos baseados na evidência e referenciados como boas práticas (APA; NCTSN; SAMHSA). Esta experiência educativa pretende facilitar conversas difíceis, mas importantes, e a prática de estratégias nos distintos contextos educativos. Adotou-se uma metodologia fundamentalmente qualitativa, que permitiu a análise de seis (6) depoimentos de profissionais que utilizaram este recurso em contexto não formal de educação. As histórias infantis, de livre acesso, editadas pela Piplo Productions, com o apoio da Fundação Irving Harris e da Rede de Tratamento de Trauma Precoce da Universidade da Califórnia e do Centro Nacional da Rede Nacional de Stress Traumático Infantil, da Administração de Serviços de Saúde Mental e Abuso de Substâncias, Departamento de Saúde e Serviços Humanos dos EUA, foram traduzidas e adaptadas para português por Magalhães et al. (2021; 2022), por se considerar relevante trazer para o nosso contexto recursos que permitem apoiar pais/educadores, profissionais e as crianças que atravessam momentos de maior desafio.info:eu-repo/semantics/publishedVersio
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
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