117,472 research outputs found
Executive deficits in elderly patients with major unipolar depression
No full textSeveral studies have evaluated executive function in depressed patients, and the results vary from significant impairment relative to controls to virtually intact performances. To better comprehend executive impairment in elderly patients with major unipolar depression, the performance of 21 elderly depressed patients was compared with that of 19 elderly normal controls on executive tasks. The relationships between memory deficits and depression severity and between memory deficits and executive dysfunction were also examined. Depressed patients' performance was significantly worse than that of controls on almost all executive tasks. Their score for logical memory was significantly correlated with that for several executive tasks. Executive performance was also correlated with depression severity. Unipolar depressed patients present executive deficits. Memory failure in these patients may reflect impairment in retrieval processes, which in turn depends on executive function. Executive deficits are associated with depression severity. These results may be useful in the differential diagnosis between depression and early Alzheimer's disease. © 2004 Sage Publications
Neuropsychological examination in dementia.
No full textThe chapter reviews neuropsychological screening and diagnostic tools applied to patients with Alzheimer's disease (AD) and related disorders. The chapter analyzes the tests to be applied to detect and assess deficits in specific cognitive domains and brings home the fact that neuropsychological tests, formal or informal, have always been fundamental for the clinical diagnosis of AD and other dementias. The recent development of pharmacological treatment for AD and other dementias, and the introduction of new therapies in the near future, make the assessment of dementia at its different stages a scientific challenge of significant consequence for public health. It examines that the majority of tests used for screening and diagnosis of dementia show good sensitivity and good specificity in the moderate stage of the disease, but not in the early stage. Therefore, the need for a more solid and theoretical framework for the assessment of dementia is becoming more apparent
Topology-dependent dissociation mode of the O-H bond in monohydroxycoumarins
No full textAll possible monohydroxycoumarin derivatives are modeled using density functional theory computations in order to investigate the role of the hydroxyl group position for the radical-scavenging and antioxidant activity of these compounds. Geometry optimization is performed using the B3LYP functional with the 6-311++G(d,p) basis set. The enthalpy changes are assessed in gas phase and in implicit water using the polarized continuum model. Structure-reactivity patterns are delineated. The most reactive isomers as well as the most probable mechanism of interaction between monohydroxycoumarins and free radicals are outlined. © 2019 American Chemical Society
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Agricultural Academy
No full textAbstract UZUNOVA, E., M. GEORGIEVA, M. NIKOLOVA, S. STUDENKOV and I. TRAYKOV, 2010. Pumpkinseed (Lepomis gibbosus) distribution and abundance in litoral zones of Sand -Pit Lakes. Bulg. J. Agric. Sci., The distribution and abundance of invasive fish species Lepomis gibbosus L. inhabiting littoral zones of sandpit lakes was investigated. The study was carried out during May and June -in active breeding period for pumpkinseeds. The investigated water bodies are located along the Lesnovska River, tributary of Iskar River, Danube drainage basin. The pumpkinseed was observed in all water bodies except Chepintci Lake. The mean abundance of pumpkinseed varied between 0.2 and 24.5 (CPUE). The highest abundance was recorded in Negovan Lake. The mean total length of pumpkinseed was relatively low for all investigated sites and varied between 4.9 and 7.4 cm, corresponding to an average age of 0.7 and 2.09 years respectively. The character of a bottom and density of water vegetation significantly correlated with pumpkinseed abundance
Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?
No full textIn this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The functional locus of intrusions: Encoding or retrieval?
No full textMany current accounts of the origin of intrusions and other confabulatory-like phenomena emphasize the role of a retrieval or postretrieval deficit in these disorders. In the experiments reported herein we examine whether the presence of an interfering task at encoding elicits more intrusions in normal subjects than the presence of an interfering task at retrieval. In Experiment 1, performance in story recall without interference was compared to the performance with an interfering task at retrieval. In Experiment 2, the performance in story recall with an interfering task at encoding was compared to performance in story recall with interference at encoding and retrieval. Results suggest that interference at retrieval has no effect on the accuracy of recall and on intrusions. Interference at encoding compared to interference at encoding and retrieval (Experiment 2) had no effect on the accuracy of recall and on frequency of intrusions. Cross-experiment comparisons suggest that interference at encoding affects both the accuracy of retrieval and the probability of intrusions in recall. These results suggest that encoding processes, more than retrieval processes, have a role in eliciting intrusions
Letter from unknown writer to Jesse L. Boyce
No full textLetter to Jesse L. Boyce from unknown author (possibly Jack) about the investigation into the powder magazine located in the Grand Canyon. Some personal news is included in the letter such as the writer's marriage to the daughter of C.A. Taylor, former Supervisor of Cochise County
- …
